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1. 发明公开

EP3256131A1 ANALOGS OF 3,5-DIHYDROXYPENTANOATE FOR BONE FORMATION 审中-公开
标题翻译： 3,5-二羟基戊酸酯用于骨形成的类似物
公开(公告)号：EP3256131A1
公开(公告)日：2017-12-20
申请号：EP15882260.1
申请日：2015-10-08
申请人： Kaohsiung Medical University , Huang, ALice Y.
发明人： CHEN, Hui-Ting , HSIEH, Kuang-Chan , KAO, Chai-Lin , CHANG, Je-Ken , HO, Mei-Ling
IPC分类号： A61K31/497 , A01N37/00 , A61K38/00 , A61P19/08
CPC分类号： A61K31/505 , A61K31/22 , A61K31/40 , A61K31/4418 , A61K31/47 , A61K38/10
摘要： A method for treating low bone mineral density associated with osteopenia, osteoporosis, and other diseases is disclosed. The method comprises administrating a composition comprising a 3,5-dihydroxypentanoic acid derivative according to Formula I to a mammal. A compound of 3,5-dihydroxypentanoic acid derivative having a structure according to Formula I or Formula II is also disclosed.

2. 发明公开

EP1185187A1 IMPROVEMENT ON OFFSET PEN STRUCTURE 审中-公开
标题翻译：改进结构拱书写工具
公开(公告)号：EP1185187A1
公开(公告)日：2002-03-13
申请号：EP99925614.2
申请日：1999-06-01
申请人： Huang, ALice Y. , Liu, Boa-Shen
发明人： LIU, Boa-Shen
IPC分类号： A46B5/02 , B43K29/10
CPC分类号： B43K23/008 , B43K5/005 , B43K7/005 , B43K21/003 , B43K21/006 , B43K23/004 , B43K27/04 , B43K29/10
摘要： An offset pen has a holding portion (51) and a writing portion (53) interconnected by an intermediate portion (52) such that the holding portion and writing portion have different axes with a vacancy therebetween. The vacancy provides a line of sight on either side of the writing tip (532) during use of the pen.

3. 发明公开

EP2519244A1 EXTRACT OF TOONA SINENSIS FROM SUPERCRITICAL FLUID EXTRACTION FOR TREATING DIABETES AND METABOLIC DISEASES, THE PREPARATION METHOD AND THE USE THEREOF 审中-公开
标题翻译：摘自中国蔬菜树从糖尿病和代谢性疾病和工艺的处理超临界流体及其制造和使用
公开(公告)号：EP2519244A1
公开(公告)日：2012-11-07
申请号：EP10841626.4
申请日：2010-12-28
申请人： Kaohsiung Medical University , Huang, ALice Y.
发明人： LIEN, Pei-Jung , SUN, Chuan-Chia , KUO, Tzu-Chen , YANG, Sheng-Chung , WU, Yang-Chang , CHANG, Fang-Rong , HSIEH, Tusty-Jiuan , TSAI, Yi-Hung , DU, Ying-Chi
IPC分类号： A61K35/00
CPC分类号： A61K36/58 , A23L33/105
摘要： The
Toona sinensis extract of the present invention is prepared using supercritical fluid technique, wherein the method includes steps of: (a) drying the leaves of T.
sinensis ; (b) pulverizing the leaves as particles; and (c) extracting the particles with supercritical carbon dioxide to obtain the T.
sinensis extract. This supercritical T.
sinensis extract not only can decrease blood sugar level, but also promotes lipid degradation, inhibits the formation of huge lipid droplet and improves the metabolic symptoms. Accordingly, the T.
sinensis extract further is able to be prepared as food supplement and pharmaceuticals.

4. 发明公开

EP2519244A4 EXTRACT OF TOONA SINENSIS FROM SUPERCRITICAL FLUID EXTRACTION FOR TREATING DIABETES AND METABOLIC DISEASES, THE PREPARATION METHOD AND THE USE THEREOF 审中-公开
标题翻译：摘自中国蔬菜树从糖尿病和代谢性疾病和工艺的处理超临界流体及其制造和使用
公开(公告)号：EP2519244A4
公开(公告)日：2015-05-13
申请号：EP10841626
申请日：2010-12-28
申请人： UNIV KAOHSIUNG MEDICAL , HUANG ALICE Y
发明人： LIEN PEI-JUNG , SUN CHUAN-CHIA , KUO TZU-CHEN , YANG SHENG-CHUNG , WU YANG-CHANG , CHANG FANG-RONG , HSIEH TUSTY-JIUAN , TSAI YI-HUNG , DU YING-CHI
IPC分类号： A61K35/00 , A23L1/30 , A61K36/00 , A61P3/00
CPC分类号： A61K36/58 , A23L33/105

5. 发明专利

AU2003216150A1 METHOD FOR MANUFACTURING ELECTROCHEMICAL SENSOR AND STRUCTURE THEREOF 未知
公开(公告)号：AU2003216150A1
公开(公告)日：2004-08-30
申请号：AU2003216150
申请日：2003-01-31
申请人： HUANG CHUN MU , HUANG ALICE Y
发明人： HUANG CHUN-MU
IPC分类号： G01N27/327

6. 发明专利

AU2003267970A1 STRUCTURE AND MANUFACTURING METHOD OF DISPOSABLE ELECTROCHEMICAL SENSOR STRIP 未知
公开(公告)号：AU2003267970A1
公开(公告)日：2005-01-28
申请号：AU2003267970
申请日：2003-06-17
申请人： HUANG ALICE Y , HUANG CHUN MU
发明人： HUANG CHUN-MU
IPC分类号： G01N27/30 , G01N33/487 , G01N33/543 , G01N27/327 , G01N27/333
摘要： A disposable electrochemical sensor strip is provided. The sensor strip includes an isolating sheet having at least a through hole, at least a conductive raw material mounted in the through hole, a metal film covered on the conductive raw material to form an electrode which comprises an electrode working surface for processing an electrode action, and an electrode connecting surface, at least a printed conductive film mounted on the isolating sheet and having a connecting terminal for being electrically connected to the electrode connecting surface, and a signal output terminal for outputting a measured signal produced by the electrode action.

7. 发明申请

WO2004070373A1 METHOD FOR MANUFACTURING ELECTROCHEMICAL SENSOR AND STRUCTURE THEREOF 审中-公开
标题翻译：制造电化学传感器及其结构的方法
公开(公告)号：WO2004070373A1
公开(公告)日：2004-08-19
申请号：PCT/US2003/003084
申请日：2003-01-31
申请人： HUANG, Alice, Y. , HUANG, Chun-Mu
发明人： HUANG, Chun-Mu
IPC分类号： G01N27/327
CPC分类号： G01N27/3272 , Y10T29/49002
摘要： A method for manufacturing an electrochemical sensor and a structure thereof are provided. The method includes steps of (a) providing an injection-molding device, (b) providing an isolating substrate (40) having a first recess (50) and a first through hole (41), (c) positing the isolating substrate (40) in the injection-molding device, (d) injecting a conductive plastic material into the injection-molding device for forming a conductive strip (42) disposed in the first recess (50) and including an output terminal and a testing electrode (44) disposed in the first through hole (41), (e) providing a chemical reagent, and (f) positing the chemical reagent on the testing electrode (44) for testing a sample solution.
摘要翻译：提供了一种用于制造电化学传感器的方法及其结构。该方法包括以下步骤：（a）提供注射成型装置，（b）提供具有第一凹部（50）和第一通孔（41）的隔离基底（40），（c）将隔离基底），（d）将导电塑料材料注入到所述注射成型装置中，以形成设置在所述第一凹部（50）中的导电条（42），并且包括输出端子和测试电极（44）设置在第一通孔（41）中，（e）提供化学试剂，和（f）将化学试剂放置在测试电极（44）上以测试样品溶液。

8. 发明申请

WO2016130181A1 ANALOGS OF 3,5-DIHYDROXYPENTANOATE FOR BONE FORMATION 审中-公开
标题翻译：用于骨形成的3,5-二羟基戊酸酯的模拟物
公开(公告)号：WO2016130181A1
公开(公告)日：2016-08-18
申请号：PCT/US2015/054692
申请日：2015-10-08
申请人： KAOHSIUNG MEDICAL UNIVERSITY , HUANG, Alice Y.
发明人： CHEN, Hui-Ting , HSIEH, Kuang-Chan , KAO, Chai-Lin , CHANG, Je-Ken , HO, Mei-Ling
IPC分类号： A61K31/497 , A01N37/00 , A61K38/00 , A61P19/08
CPC分类号： A61K31/505 , A61K31/22 , A61K31/40 , A61K31/4418 , A61K31/47 , A61K38/10
摘要： A method for treating low bone mineral density associated with osteopenia, osteoporosis, and other diseases is disclosed. The method comprises administrating a composition comprising a 3,5-dihydroxypentanoic acid derivative according to Formula I to a mammal. A compound of 3,5-dihydroxypentanoic acid derivative having a structure according to Formula I or Formula II is also disclosed.
摘要翻译：公开了一种治疗与骨质减少，骨质疏松症和其他疾病相关的低骨矿物质密度的方法。该方法包括向哺乳动物施用包含式I的3,5-二羟基戊酸衍生物的组合物。还公开了具有式I或式II结构的3,5-二羟基戊酸衍生物的化合物。

9. 发明申请

WO2008147365A1 COMPOSITION FOR INCREASING INTRACELLULAR NITRIC OXIDE AND METHOD FOR THE SAME 审中-公开
标题翻译：用于增加细胞内氮氧化物的组合物及其方法
公开(公告)号：WO2008147365A1
公开(公告)日：2008-12-04
申请号：PCT/US2007/012977
申请日：2007-06-01
申请人： NATIONAL APPLIED RESEARCH LABORATORIES , TAIPEI MEDICAL UNIVERSITY , HUANG, Alice, Y. , LEUNG, Ting-Kai , HO, Yuan-Soon , SHANG, Huey-Fang , LEE, Yi-Hsuan , LIN, Yung-Sheng , LIN, Ming-Yu , KAO, Jiann-Shiun
发明人： LEUNG, Ting-Kai , HO, Yuan-Soon , SHANG, Huey-Fang , LEE, Yi-Hsuan , LIN, Yung-Sheng , LIN, Ming-Yu , KAO, Jiann-Shiun
IPC分类号： A61K49/00
CPC分类号： A61K41/0057 , A61K41/0019
摘要： A composition and a method for increasing intracellular nitric oxide is provided. The composition comprises a far-infrared ray releasing substance composed mainly of an oxide mineral for releasing a far-infrared ray, wherein the composition promotes generation of the nitric oxide via irradiation of the far-infrared ray from the far-infrared ray releasing substance. In another aspect, the method comprises setting an effective amount of a far-infrared ray releasing substance in a place close to a cell with an appropriate distance, and incubating the far-infrared ray releasing substance with the cell for a specific period, wherein the appropriate distance lies in an irradiation range of the far-infrared ray releasing substance.
摘要翻译：提供了一种用于增加细胞内一氧化氮的组合物和方法。该组合物包括主要由用于释放远红外线的氧化物矿物质组成的远红外线释放物质，其中该组合物通过远红外线释放物质的远红外线照射促进一氧化氮的产生。另一方面，该方法包括在适当距离的细胞附近设置有效量的远红外线释放物质，并将远红外线释放物质与细胞一起培养一段时间，其中适当的距离位于远红外线释放物质的照射范围内。

10. 发明申请

WO2005047877A1 ELECTROCHEMICAL SENSING DEVICE 审中-公开
标题翻译：电化学传感装置
公开(公告)号：WO2005047877A1
公开(公告)日：2005-05-26
申请号：PCT/US2004/036730
申请日：2004-11-04
申请人： BIONIME , HUANG, Alice, Y. , HUANG, Chun-Mu
发明人： HUANG, Chun-Mu
IPC分类号： G01N27/403
CPC分类号： A61B5/14532 , G01N33/48785 , G06F19/00
摘要： An electrochemical sensing device is provided. The electrochemical sensing device includes a main body (11) having a connecting slot (111), a testing holder (14) having a detachable connection to the connecting slot (111) and having a storage component (141), and an electrochemical sensing strip (13) detachably combined with the testing holder (14) for analyzing a sample.
摘要翻译：提供了一种电化学传感装置。电化学感测装置包括具有连接槽（111）的主体（11），具有与连接槽（111）的可拆卸连接并且具有存储部件（141）的测试夹具（14），以及电化学传感条（13）可拆卸地与用于分析样品的测试保持器（14）组合。

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