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1. 实用新型

TWM314595U 身體拉伸裝置失效
简体标题：身体拉伸设备
公开(公告)号：TWM314595U
公开(公告)日：2007-07-01
申请号：TW095218777
申请日：2006-10-24
申请人：陳海倫 HELEN CHEN
发明人：李杰 JAY LEE , 陳海倫 HELEN CHEN
IPC分类号： A61H
摘要：一種身體拉伸裝置，係於一薄型盒內包含一腳跟拉伸結構與一小腿伸展結構，該腳跟拉伸結構具有一滑動腳架和一驅動機構，藉由操作驅動機構來控制滑動腳架滑移的距離，進而拉動固定在滑動腳架上的腳跟以達到身體伸展；該小腿伸展結構具有一對連桿，連桿之間橫設一腳趾限位棍，連桿可由水平轉至垂直位置，此時，腳趾緊靠於限位棍上而腳跟固定在滑動腳架上，腳部形成蹠屈(plantar flexion)樣態，拉伸腳跟便進而拉伸腳跟腱(Achilles tendon)與小腿後肌群；上述盒體主要包含一個兩段式摺疊的盒蓋，盒體大致為一個手提電腦般大小，欲收合時將腳跟拉伸結構與小腿伸展結構放置盒內，蓋上盒蓋後便於收藏與攜帶。
简体摘要：一种身体拉伸设备，系于一薄型盒内包含一脚跟拉伸结构与一小腿伸展结构，该脚跟拉伸结构具有一滑动脚架和一驱动机构，借由操作驱动机构来控制滑动脚架滑移的距离，进而拉动固定在滑动脚架上的脚跟以达到身体伸展；该小腿伸展结构具有一对连杆，连杆之间横设一脚趾限位棍，连杆可由水平转至垂直位置，此时，脚趾紧靠于限位棍上而脚跟固定在滑动脚架上，脚部形成跖屈(plantar flexion)样态，拉伸脚跟便进而拉伸脚跟腱(Achilles tendon)与小腿后肌群；上述盒体主要包含一个两段式折叠的盒盖，盒体大致为一个手提电脑般大小，欲收合时将脚跟拉伸结构与小腿伸展结构放置盒内，盖上盒盖后便于收藏与携带。

2. 发明授权

US09918590B2 Food preparation device 有权
公开(公告)号：US09918590B2
公开(公告)日：2018-03-20
申请号：US14171578
申请日：2014-02-03
申请人： Haidee Chen , Helen Chen
发明人： Haidee Chen , Helen Chen
IPC分类号： A47J43/04 , A47J27/08 , A47J36/32
CPC分类号： A47J43/04 , A47J27/08 , A47J27/0802 , A47J36/32
摘要： A food preparation device or system which includes the following: (i) a base dimensioned to hold food containers and includes a first opening to receive the food containers and a second opening; (ii) an extraction mechanism to extract food items from each container in the base, through the second opening and to a preparation receptacle; (iii) a heating mechanism in the preparation receptacle; and (iv) one or more processors and memory containing instructions that, when executed cause the food preparation device or system to prepare the food items for consumption.

3. 发明授权

US08440643B2 Inhibitors of beta-lactamase 失效
标题翻译： β-内酰胺酶抑制剂
公开(公告)号：US08440643B2
公开(公告)日：2013-05-14
申请号：US12301797
申请日：2007-05-21
申请人： Frank Dininno , Milton L. Hammond , Kevin Dykstra , Seongkon Kim , Qiang Tan , Katherine Young , Jeffrey Donald Hermes , Helen Chen , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Arkadii Vaisburg , Jubrail Rahil , Nafsika Georgopapadakou , Nancy Z. Zhou
发明人： Frank Dininno , Milton L. Hammond , Kevin Dykstra , Seongkon Kim , Qiang Tan , Katherine Young , Jeffrey Donald Hermes , Helen Chen , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Arkadii Vaisburg , Jubrail Rahil , Nafsika Georgopapadakou , Nancy Z. Zhou
IPC分类号： A61K31/675 , A61K31/67 , A61K31/665
CPC分类号： C07F9/655354 , C07F9/65395 , C07F9/6541 , C07F9/6553 , C07F9/6558 , C07F9/6561
摘要： This invention provides novel β-lactamase inhibitors of the aryl- and heteroaryl-sulfonamidomethylphosphonate monoester class having nitrogen-based cations or quarternary ammomium groups. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazimdime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases.
摘要翻译：本发明提供具有氮基阳离子或季铵基团的芳基 - 和杂芳基 - 磺酰氨基甲基膦酸酯单酯类的新型β-内酰胺酶抑制剂。这些化合物抑制三类β-内酰胺酶，并与β-内酰胺类抗生素（如亚胺培南和头孢他啶）的抗菌作用协同作用，因为β-内酰胺酶的存在对通常对β-内酰胺抗生素有抗性的微生物。

4. 发明申请

US20080084951A1 Systems and methods for receiving multiple input, multiple output signals for test and analysis of multiple-input, multiple-output systems 审中-公开
标题翻译：用于接收多输入多输出信号的系统和方法，用于多输入多输出系统的测试和分析
公开(公告)号：US20080084951A1
公开(公告)日：2008-04-10
申请号：US11544421
申请日：2006-10-06
申请人： Helen Chen , Brian J. Avenell , Gordon R. Strachan , Michael C. Lawton
发明人： Helen Chen , Brian J. Avenell , Gordon R. Strachan , Michael C. Lawton
IPC分类号： H04B7/10
CPC分类号： H04B7/04 , H04B17/0087 , H04L1/06
摘要： Systems and methods for receiving MIMO signals for testing and analyzing operation of MIMO communications devices. Examples of systems and/or methods for receiving MIMO signals include a measuring receiver with N RF paths consisting of N downconverters. Each downconverter achieves a frequency shift of the input MIMO signal equal to a shifting frequency of a first intermediate frequency (IF) plus a delta determined by the signal bandwidth multiplied by an integer number between 1 and N. The shifted N MIMO signals are combined to generate one combined analog MIMO signal. An analog to digital converter converts the combined analog MIMO signal to a stream of digital samples where the samples may be tested and analyzed with metrics on signals communicated in a MIMO environment. Example systems and method for receiving MIMO signals may also be implemented as a MIMO channel emulator such that samples generated by the ADC may be upconverted to output copies of the original signals to a receiver DUT, for example.
摘要翻译：用于接收MIMO信号以测试和分析MIMO通信设备的操作的系统和方法。用于接收MIMO信号的系统和/或方法的示例包括具有由N个下变频器组成的N个RF路径的测量接收机。每个下变频器实现输入MIMO信号的频移等于第一中间频率（IF）的移位频率加上由信号带宽乘以1与N之间的整数确定的增量。移位的N个MIMO信号被组合到生成一个组合的模拟MIMO信号。模数转换器将组合的模拟MIMO信号转换成数字样本流，其中样本可以通过在MIMO环境中传送的信号的度量进行测试和分析。用于接收MIMO信号的示例系统和方法也可以被实现为MIMO信道仿真器，使得例如由ADC生成的采样可以被上变频以将原始信号的副本输出到接收机DUT。

5. 发明授权

US6110944A LTA.sub.4, hydrolase inhibitors 失效
标题翻译： LTA4，水解酶抑制剂
公开(公告)号：US6110944A
公开(公告)日：2000-08-29
申请号：US814899
申请日：1997-03-12
申请人： Barbara Baosheng Chen , Helen Chen , Mark Andrew Russell
发明人： Barbara Baosheng Chen , Helen Chen , Mark Andrew Russell
IPC分类号： C07D295/12 , A61K31/155 , A61K31/4164 , A61K31/4184 , A61K31/445 , A61K31/4453 , A61P1/04 , A61P11/06 , A61P17/06 , A61P29/00 , A61P43/00 , C07C255/12 , C07C257/06 , C07C257/14 , C07C259/14 , C07D211/62 , C07D233/10 , C07D233/18 , C07D233/22 , C07D235/12 , C07D295/185 , C07C69/76 , C07D207/04 , C07D211/60
CPC分类号： C07D295/185 , C07C255/12 , C07C257/06 , C07C257/14 , C07D211/62 , C07D233/22 , C07D235/12 , C07C2103/74
摘要： The present invention provides compounds having the structureAr.sub.1 --Q--Ar.sub.2 --O--(CH.sub.2).sub.n --Zand pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
摘要翻译：本发明提供了具有结构式为Ar1-Q-Ar2-O-（CH2）n-Zand及其药学上可接受的盐和立体异构体的化合物，其可用于治疗由LTB4产生介导的炎性疾病，例如牛皮癣，溃疡性结肠炎， IBD和哮喘。

6. 发明授权

US5925654A LTA.sub.4 , hydrolase inhibitors 失效
标题翻译： LTA4水解酶抑制剂
公开(公告)号：US5925654A
公开(公告)日：1999-07-20
申请号：US815696
申请日：1997-03-12
申请人： Barbara Baosheng Chen , Helen Chen , Mark Andrew Russell , Julie Marion Miyashiro , James Malecha , Thomas Dale Penning
发明人： Barbara Baosheng Chen , Helen Chen , Mark Andrew Russell , Julie Marion Miyashiro , James Malecha , Thomas Dale Penning
IPC分类号： C07D295/08 , A61K31/195 , A61K31/40 , A61K31/421 , A61K31/422 , A61K31/426 , A61K31/445 , A61P1/04 , A61P11/06 , A61P17/06 , A61P29/00 , A61P43/00 , C07C229/12 , C07D211/62 , C07D263/32 , C07D277/24 , C07D295/092 , C07D207/08 , C07D207/325
CPC分类号： C07D295/088 , C07C229/12 , C07D211/62 , C07D263/32 , C07D277/24
摘要： The present invention provides compounds having the structure: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
摘要翻译：本发明提供具有以下结构的化合物及其药学上可接受的盐和立体异构体，其可用于治疗由LTB4产生介导的炎性疾病，例如牛皮癣，溃疡性结肠炎，IBD和哮喘。

7. 外观设计

USD798057S1 Tote shell 有权
公开(公告)号：USD798057S1
公开(公告)日：2017-09-26
申请号：US29544581
申请日：2015-11-04
申请人： Jan Hsin Lo , Derek Pei-Hsin Lo , Helen Chen Lo
设计人： Jan Hsin Lo , Derek Pei-Hsin Lo , Helen Chen Lo

8. 发明申请

US20170217918A1 ANTIDIABETIC BICYCLIC COMPOUNDS 审中-公开
公开(公告)号：US20170217918A1
公开(公告)日：2017-08-03
申请号：US15328735
申请日：2015-08-06
申请人： Helen CHEN , Steven L. COLLETTI , Duane MONG , Yan GUO , Michael MILLER , Anilkumar NAIR , Christopher W. PLUMMER , Dong XIAO , De-Yi YANG , Merck Sharp & Dohme Corp.
发明人： Helen Chen , Steven L. Colletti , Duane DeMong , Yan Guo , Michael Miller , Anilkumar Nair , Christopher W. Plummer , Dong Xiao , De-Yi Yang
IPC分类号： C07D311/60 , C07D405/14 , C07D471/08 , C07D487/08 , C07D487/04 , C07D491/107 , C07D413/12 , C07D491/08 , C07D405/10 , C07D491/048
CPC分类号： C07D311/60 , A61K31/366 , A61K31/397 , A61K31/4985 , A61K45/06 , C07D405/10 , C07D405/14 , C07D413/12 , C07D413/14 , C07D451/02 , C07D471/08 , C07D487/04 , C07D487/08 , C07D491/048 , C07D491/08 , C07D491/107 , A61K2300/00
摘要： Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

9. 发明申请

US20150216362A1 SYSTEM AND METHOD FOR OPERATING A FOOD PREPARATION DEVICE 审中-公开
标题翻译：用于操作食品制备装置的系统和方法
公开(公告)号：US20150216362A1
公开(公告)日：2015-08-06
申请号：US14171539
申请日：2014-02-03
申请人： Helen Chen , Haidee Chen
发明人： Haidee Chen , Helen Chen
IPC分类号： A47J44/00
摘要： A food preparation device or system which utilizes pre-packaged food containers to prepare a food item for consumption.
摘要翻译：一种食物制备装置或系统，其利用预先包装的食物容器来制备用于食物的食品。

10. 发明申请

US20100279983A1 NOVEL INHIBITORS OF BETA-LACTAMASE 失效
标题翻译： β-LACTAMASE的新型抑制剂
公开(公告)号：US20100279983A1
公开(公告)日：2010-11-04
申请号：US12301797
申请日：2007-05-21
申请人： Frank Dininno , Milton L. Hammond , Kevin Dykstra , Seongkon Kim , Qiang Tan , Katherine Young , Jeffrey Donald Hermes , Helen Chen , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Arkadii Vaisburg , Jubrail Rahil , Nafsika Georgopapadakou , Nancy Z. Zhou
发明人： Frank Dininno , Milton L. Hammond , Kevin Dykstra , Seongkon Kim , Qiang Tan , Katherine Young , Jeffrey Donald Hermes , Helen Chen , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Arkadii Vaisburg , Jubrail Rahil , Nafsika Georgopapadakou , Nancy Z. Zhou
IPC分类号： A61K31/675 , A61K31/67 , A61K31/665 , C07D409/12 , C07D277/80 , C07D277/36 , C07D333/72 , C07D307/83 , A61P31/04
CPC分类号： C07F9/655354 , C07F9/65395 , C07F9/6541 , C07F9/6553 , C07F9/6558 , C07F9/6561
摘要： This invention provides novel β-lactamase inhibitors of the aryl- and heteroarylsulfonamidomethylphosphonate monoester class having nitrogen-based cations or quarternary ammonium groups. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazidime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. Formula (I) or pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供具有氮基阳离子或季铵基团的芳基 - 和杂芳基磺酰氨基甲基膦酸酯单酯类的新颖的β-内酰胺酶抑制剂。这些化合物抑制三种类型的β-内酰胺酶，并且与通常对β-内酰胺抗生素具有抗性的那些微生物相互作用可促进β-内酰胺类抗生素（如亚胺培南和头孢他啶）对抗生素的抗菌作用。＆bgr;内酰胺酶。式（I）或其药学上可接受的盐。

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