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1. 发明申请

WO2005107836A1 QUANTITATIVE CHRONOLOGICAL MEDICAL INFUSION DEVICE 审中-公开
标题翻译：定量CHRONOLOGICAL MEDICAL INFUSION DEVICE
公开(公告)号：WO2005107836A1
公开(公告)日：2005-11-17
申请号：PCT/IB2005/001516
申请日：2005-05-06
申请人： BIONICA INTERNATIONAL NV , GILBERT, Gregory, Ford
发明人： GILBERT, Gregory, Ford
IPC分类号： A61M5/145
CPC分类号： A61M5/14566 , A61M5/1723 , A61M2005/14208 , A61M2205/123 , A61M2205/6018
摘要： The present invention is a medical infusion and aspiration system delivering precisely timed and accurately calculated, adjusted pulsated delivery in high rates of flow delivering an effective profile of pulses tailored to provide momentary spikes of levels of freely available medicines based upon the uptake of the medicine and optimally on real time measurements of the medicine or response of the patient, termed Quantitative Chronological Delivery. The system comprises any pumping mechanism, and optimally a pumping mechanism, and a cassette or cartridge having a reservoir area where the plunger rotates as it advances in reference to the cartridge to provide additional accuracy and overcome the forces of inertia and slip-stick as well as eliminate backlash. Optimally, the systems incorporates an encoded area and an opening for connection to an infusion tube with an in-line sensor area where sampling probes are located. The infusion is adjusted in both amount and duration between pulses to provide quantitatively controlled, chronologically optimized infusion. A motor causes bi-directional pumping to allow for samples to be presented to the sensor area. The system accuracy allows for more concentrated medicines, as a sealed container can eliminate the need for diluting or withdrawing medicine to load a reservoir, and achieves extraordinary accuracy without error correcting software or expensive volumetric measurement and control systems.
摘要翻译：本发明是医疗输液和抽吸系统，其以高流速提供精确定时和精确计算的调节的脉动递送，其提供有效的脉冲轮廓，其基于药物的摄取而定制以提供可免费获得的药物的瞬间尖峰水平，最佳地实时测量患者的药物或反应，称为定量时间递送。该系统包括任何泵送机构，以及最佳的泵送机构，以及具有储存区域的盒或盒，当存储器区域随着其相对于盒的前进而旋转，以提供额外的精度并克服惯性力和滑棒的力作为消除反弹。最佳地，系统包含编码区域和用于连接到具有采样探针所在的在线传感器区域的输液管的开口。在脉冲之间调节输液量和持续时间以提供定量控制的，按时间顺序优化的输液。电动机引起双向泵送，以允许将样品呈现给传感器区域。系统精度允许更集中的药物，因为密封容器可以消除稀释或取出药物以加载储存器的需要，并且在没有误差校正软件或昂贵的体积测量和控制系统的情况下实现非凡的精度。

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