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1. 发明申请

WO2010124235A1 USE ADIPOSE TISSUE-DERIVED REGENERATIVE CELLS IN THE MODULATION OF INFLAMMATION IN THE PANCREAS AND IN THE KIDNEY 审中-公开
标题翻译：在胰腺和胃肠炎的调节中使用ADIPOSE TISSUE衍生的再生细胞
公开(公告)号：WO2010124235A1
公开(公告)日：2010-10-28
申请号：PCT/US2010/032275
申请日：2010-04-23
申请人： CYTORI THERAPEUTICS, INC. , PINKERNELL, Kai , FENG, Zheng
发明人： PINKERNELL, Kai , FENG, Zheng
IPC分类号： C12N5/077 , C12N5/0775 , A61P1/18
CPC分类号： A61K35/28 , A61K35/12 , C12N5/0653 , C12N5/0667
摘要： Aspects of the present invention relate to the field of medicine, specifically, the effect of adipose tissue and its components on modulating inflammation.
摘要翻译：本发明的方面涉及药物领域，具体地说，涉及脂肪组织及其组分对调节炎症的作用。

2. 发明申请

WO2006137836A2 BACTERIAL VECTOR SYSTEMS 审中-公开
标题翻译：细菌载体系统
公开(公告)号：WO2006137836A2
公开(公告)日：2006-12-28
申请号：PCT/US2005/029263
申请日：2005-08-17
申请人： RESEARCH DEVELOPMENT FOUNDATION , PAYNE, Shelley, M. , DUDLEY, Jacquelin, P. , SELIGER, Stefan, S. , FENG, Zheng, Y.
发明人： PAYNE, Shelley, M. , DUDLEY, Jacquelin, P. , SELIGER, Stefan, S. , FENG, Zheng, Y.
CPC分类号： C12N15/70 , A61K48/0008 , C07K2319/036 , C07K2319/80 , C12N15/62 , C12N15/63
摘要： The present invention provides bacterial vectors and fusion proteins containing a TTSS polypeptide, compositions of such fusion proteins including polynucleotides, and methods of delivering one or more genes into a target cell that involve contacting the cell with a composition that includes such a fusion protein. Compositions and methods of gene delivery that involve a bacterium and a TAT, Antp, or HSV VP22 polypeptide are also disclosed. The invention also concerns methods of delivering one or more genes into a target cell utilizing a bacterium capable of becoming internalized within the cell, wherein the bacterium includes one or more genes targeted for delivery to the cell, a gene encoding an RNA polymerase, and a gene that causes lysis of the bacterium.
摘要翻译：本发明提供了包含TTSS多肽的细菌载体和融合蛋白，包括多核苷酸的这种融合蛋白的组合物，以及将一种或多种基因递送至靶细胞的方法，所述靶细胞涉及使细胞与包含这种融合蛋白的组合物接触。还公开了涉及细菌和TAT，Antp或HSV VP22多肽的基因递送的组合物和方法。本发明还涉及使用能够在细胞中内化的细菌将一种或多种基因递送至靶细胞的方法，其中细菌包括靶向递送至细胞的一种或多种基因，编码RNA聚合酶的基因和引起细菌裂解的基因。

3. 发明申请

WO2006137836A3 BACTERIAL VECTOR SYSTEMS 审中-公开
标题翻译：细菌载体系统
公开(公告)号：WO2006137836A3
公开(公告)日：2007-11-08
申请号：PCT/US2005029263
申请日：2005-08-17
申请人： RES DEV FOUNDATION , PAYNE SHELLEY M , DUDLEY JACQUELIN P , SELIGER STEFAN S , FENG ZHENG Y
发明人： PAYNE SHELLEY M , DUDLEY JACQUELIN P , SELIGER STEFAN S , FENG ZHENG Y
IPC分类号： C12N15/62 , A61K48/00 , C12N15/87
CPC分类号： C12N15/70 , A61K48/0008 , C07K2319/036 , C07K2319/80 , C12N15/62 , C12N15/63
摘要： The present invention provides bacterial vectors and fusion proteins containing a TTSS polypeptide, compositions of such fusion proteins including polynucleotides, and methods of delivering one or more genes into a target cell that involve contacting the cell with a composition that includes such a fusion protein. Compositions and methods of gene delivery that involve a bacterium and a TAT, Antp, or HSV VP22 polypeptide are also disclosed. The invention also concerns methods of delivering one or more genes into a target cell utilizing a bacterium capable of becoming internalized within the cell, wherein the bacterium includes one or more genes targeted for delivery to the cell, a gene encoding an RNA polymerase, and a gene that causes lysis of the bacterium.
摘要翻译：本发明提供了包含TTSS多肽的细菌载体和融合蛋白，包括多核苷酸的这种融合蛋白的组合物，以及将一种或多种基因递送至靶细胞的方法，所述靶细胞涉及使细胞与包含这种融合蛋白的组合物接触。还公开了涉及细菌和TAT，Antp或HSV VP22多肽的基因递送的组合物和方法。本发明还涉及使用能够在细胞中内化的细菌将一种或多种基因递送至靶细胞的方法，其中细菌包括靶向递送至细胞的一种或多种基因，编码RNA聚合酶的基因和引起细菌裂解的基因。

4. 发明授权

US09347947B2 Immunoassays employing non-particulate chemiluminescent reagent 有权
标题翻译：免疫测定采用非微粒化学发光试剂
公开(公告)号：US09347947B2
公开(公告)日：2016-05-24
申请号：US12403299
申请日：2009-03-12
申请人： Pratap Singh , Yi Feng Zheng , Liping Geng , Roland Janzen , Carsten Schelp
发明人： Pratap Singh , Yi Feng Zheng , Liping Geng , Roland Janzen , Carsten Schelp
IPC分类号： G01N21/76 , G01N33/58
CPC分类号： G01N33/78 , G01N33/582 , G01N2333/59
摘要： Methods and reagents are disclosed for conducting assays. Embodiments of the present methods and reagents are concerned with chemiluminescent reagents for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte. The reagent is non-particulate and comprises a binding partner for the analyte and a chemiluminescent composition comprising an olefinic compound and a metal chelate. In embodiments of an assay, a combination is provided that comprises a sample suspected of containing the analyte, a chemiluminescent reagent as described above and a sensitizer reagent capable of generating singlet oxygen. The combination is subjected to conditions for binding of the analyte to the binding partner for the analyte. The sensitizer is activated and the amount of luminescence generated by the chemiluminescent composition is detected wherein the amount of luminescence is related to the amount of the analyte in the sample.
摘要翻译：公开了用于进行测定的方法和试剂。本发明方法和试剂的实施方案涉及用于确定怀疑含有分析物的样品中分析物的存在和/或量的化学发光试剂。试剂是非颗粒的并且包含用于分析物的结合配偶体和包含烯属化合物和金属螯合物的化学发光组合物。在测定的实施方案中，提供了包含疑似含有分析物的样品，如上所述的化学发光试剂和能够产生单线态氧的敏化剂的组合。该组合经受用于将分析物与分析物的结合配偶体结合的条件。敏化剂被激活，并且检测由化学发光组合物产生的发光量，其中发光量与样品中分析物的量相关。

5. 发明授权

US08937985B2 Method for wirelessly transmitting data between a plurality of communication units arranged in a rotating component and rotating component 有权
标题翻译：用于在布置在旋转部件中的多个通信单元和旋转部件之间无线地发送数据的方法
公开(公告)号：US08937985B2
公开(公告)日：2015-01-20
申请号：US13390262
申请日：2010-08-10
申请人： Claus Kupferschmidt , Amina Ayadi-Miessen , Feng Zheng
发明人： Claus Kupferschmidt , Amina Ayadi-Miessen , Feng Zheng
IPC分类号： H04B1/00 , H04B1/719 , H04B1/7183
CPC分类号： H04B1/719 , H04B1/7183
摘要： A method for the wireless transmission of data between at least one communication unit (2) which is arranged in or on a rotatable part (1) and to which at least one sensor (S) and/or actuator is respectively connected, and at least one base communication unit (4) which is arranged in radio reception range outside of the rotatable part is described. Transmission of the data using the ultrawideband radio transmission method (UWB) on a frequency spectrum of more than 500 MHz or a frequency bandwidth of more than 0.2 times the average transmission frequency is proposed.
摘要翻译：一种用于在布置在可旋转部分（1）中或其上的至少一个通信单元（2）和至少一个传感器（S）和/或致动器分别连接到其之间的数据无线传输的方法，并且至少描述了在可旋转部分的无线电接收范围内布置的一个基站通信单元（4）。提出了使用超宽带无线电传输方法（UWB）在超过500MHz的频谱上的数据或频率带宽大于平均传输频率的0.2倍的数据传输。

6. 发明授权

US08652237B2 System and process for capture of H2S from gaseous process streams and process for regeneration of the capture agent 有权
标题翻译：用于从气态工艺流捕获H 2 S的系统和过程以及捕获剂再生的过程
公开(公告)号：US08652237B2
公开(公告)日：2014-02-18
申请号：US12972125
申请日：2010-12-17
申请人： David J. Heldebrant , Phillip K. Koech , James E. Rainbolt , Mark D. Bearden , Feng Zheng
发明人： David J. Heldebrant , Phillip K. Koech , James E. Rainbolt , Mark D. Bearden , Feng Zheng
IPC分类号： B01D53/14
CPC分类号： B01D53/1493 , B01D53/1425 , B01D53/1468 , B01D2252/20484 , B01D2252/20489 , B01D2252/40 , B01D2252/502
摘要： A system and process are disclosed for selective removal and recovery of H2S from a gaseous volume, e.g., from natural gas. Anhydrous organic, sorbents chemically capture H2S gas to form hydrosulfide salts. Regeneration of the capture solvent involves addition of an anti-solvent that releases the captured H2S gas from the capture sorbent. The capture sorbent and anti-solvent are reactivated for reuse, e.g., by simple distillation.
摘要翻译：公开了用于从例如天然气的气体体积选择性地除去和回收H 2 S的系统和方法。无机有机物，吸附剂化学捕获H 2 S气体形成硫氢化物盐。捕获溶剂的再生包括加入从捕获吸附剂释放所捕获的H 2 S气体的抗溶剂。捕获的吸附剂和抗溶剂被再活化以便再利用，例如通过简单的蒸馏。

7. 发明申请

US20130056676A1 SYSTEM AND PROCESS FOR POLARITY SWING ASSISTED REGENERATION OF GAS SELECTIVE CAPTURE LIQUIDS 有权
标题翻译：系统和过程的极地挥发辅助再生气体选择性液体液体
公开(公告)号：US20130056676A1
公开(公告)日：2013-03-07
申请号：US13224680
申请日：2011-09-02
申请人： David J. Heldebrant , Ward E. Tegrotenhuis , Charles J. Freeman , Michael L. Elliott , Phillip K. Koech , Paul H. Humble , Feng Zheng , Jian Zhang
发明人： David J. Heldebrant , Ward E. Tegrotenhuis , Charles J. Freeman , Michael L. Elliott , Phillip K. Koech , Paul H. Humble , Feng Zheng , Jian Zhang
IPC分类号： C01B31/16 , B01J19/00 , C07C277/08
CPC分类号： B01D53/1425 , B01D53/1475 , B01D53/1481 , B01D53/1493 , B01D2252/30 , B01D2257/308 , B01D2258/0233 , B01D2258/0283 , Y02B30/52 , Y02C10/06 , Y02P20/129
摘要： A polarity swing-assisted regeneration (PSAR) process is disclosed for improving the efficiency of releasing gases chemically bound to switchable ionic liquids. Regeneration of the SWIL involves addition of a quantity of non-polar organic compound as an anti-solvent to destabilize the SWIL, which aids in release of the chemically bound gas. The PSAR decreases gas loading of a SWIL at a given temperature and increases the rate of gas release compared to heating in the absence of anti-solvent.
摘要翻译：公开了极性摆动辅助再生（PSAR）方法，用于提高释放与可切换离子液体结合的气体的释放效率。 SWIL的再生包括加入一定量的非极性有机化合物作为抗溶剂以使SWIL稳定化，这有助于化学结合气体的释放。 PSAR在给定温度下降低了SWIL的气体负荷，并且在不存在抗溶剂的情况下，与加热相比，气体释放速率增加。

8. 发明授权

US07842475B2 Stabilization of solid support assay reagents 有权
标题翻译：固体支持测定试剂的稳定化
公开(公告)号：US07842475B2
公开(公告)日：2010-11-30
申请号：US11970658
申请日：2008-01-08
申请人： Yi Feng Zheng , Tie Q. Wei
发明人： Yi Feng Zheng , Tie Q. Wei
IPC分类号： G01N33/53
CPC分类号： G01N33/54353 , C12Q1/6834 , G01N33/54333
摘要： Reagents are disclosed for use in assays for analytes. The reagents are dry assay reagents that may be readily reconstituted for use in the assays. The dry assay reagents comprise a solid support and one or more molecules of a receptor immobilized on the solid support. The receptor comprises one or more binding sites for a ligand. A portion of a total number of the binding sites is bound to a conjugate comprising the ligand linked to a specific binding pair member and a portion of the total number of the binding sites is free. In use in an assay, a combination is provided in an aqueous medium comprising the sample and reagents for detecting the analyte wherein at least one of the reagents comprises the dry assay reagent mentioned above. The combination is incubated under conditions for binding of the analyte to one or more of the reagents. The presence and/or amount of binding of the analyte to one or more of the reagents is detected where the presence and/or amount of the binding is related to the presence and/or amount of the analyte in the sample.
摘要翻译：公开了用于分析物测定的试剂。试剂是可以容易地重构用于测定中的干测定试剂。干测定试剂包含固体支持物和固定在固体支持物上的一个或多个受体分子。受体包含一个或多个配体的结合位点。结合位点总数的一部分与包含与特异性结合对成员连接的配体的缀合物结合，并且结合位点总数的一部分是游离的。在测定中使用时，在包含样品的水性介质和检测分析物的试剂中提供组合，其中至少一种试剂包含上述干试剂。将组合物在分析物与一种或多种试剂结合的条件下孵育。检测分析物与一种或多种试剂结合的存在和/或量，其中结合的存在和/或量与样品中分析物的存在和/或量相关。

9. 发明申请

US20100233725A1 IMMUNOASSAYS EMPLOYING NON-PARTICULATE CHEMILUMINESCENT REAGENT 有权
标题翻译：免费使用非颗粒性发光试剂
公开(公告)号：US20100233725A1
公开(公告)日：2010-09-16
申请号：US12403299
申请日：2009-03-12
申请人： Pratap Singh , Yi Feng Zheng , Liping Geng , Roland Janzen , Carsten Schelp
发明人： Pratap Singh , Yi Feng Zheng , Liping Geng , Roland Janzen , Carsten Schelp
IPC分类号： G01N33/53
CPC分类号： G01N33/78 , G01N33/582 , G01N2333/59
摘要： Methods and reagents are disclosed for conducting assays. Embodiments of the present methods and reagents are concerned with chemiluminescent reagents for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte. The reagent is non-particulate and comprises a binding partner for the analyte and a chemiluminescent composition comprising an olefinic compound and a metal chelate. In embodiments of an assay, a combination is provided that comprises a sample suspected of containing the analyte, a chemiluminescent reagent as described above and a sensitizer reagent capable of generating singlet oxygen. The combination is subjected to conditions for binding of the analyte to the binding partner for the analyte. The sensitizer is activated and the amount of luminescence generated by the chemiluminescent composition is detected wherein the amount of luminescence is related to the amount of the analyte in the sample.
摘要翻译：公开了用于进行测定的方法和试剂。本发明方法和试剂的实施方案涉及用于确定怀疑含有分析物的样品中分析物的存在和/或量的化学发光试剂。试剂是非颗粒的并且包含用于分析物的结合配偶体和包含烯属化合物和金属螯合物的化学发光组合物。在测定的实施方案中，提供了包含疑似含有分析物的样品，如上所述的化学发光试剂和能够产生单线态氧的敏化剂的组合。该组合经受用于将分析物与分析物的结合配偶体结合的条件。敏化剂被激活，并且检测由化学发光组合物产生的发光量，其中发光量与样品中分析物的量相关。

10. 发明申请

US20050106582A1 Compositions and methods utilizing stable reporter cell lines for detection of CREB-dependent signal transduction 审中-公开
标题翻译：使用稳定的报道细胞系检测CREB依赖性信号转导的组合物和方法
公开(公告)号：US20050106582A1
公开(公告)日：2005-05-19
申请号：US10818529
申请日：2004-04-05
申请人： Chao-Feng Zheng
发明人： Chao-Feng Zheng
IPC分类号： C12N5/06 , C12Q1/66 , C12Q1/68
CPC分类号： C12Q1/6897
摘要： A rectangular shape greeting card assembled from a flat sheet of paper, card-stock, cardboard or plastic with a hole, slit or both at the top for hanging and a gift/care package container at the bottom for a gift of any sort that can be hung from any bar, pole, rod, hook, knob or protrusion of any kind or it can be made through the process of injection molding with plastic.
摘要翻译：一张矩形形状的贺卡，由一张平纸，卡片纸，纸板或塑料制成，上面有一个孔，狭缝或两个，用于悬挂，底部还有一个礼物/护理包装容器，可以任何类型的礼物从任何杆，杆，杆，钩，旋钮或任何类型的突起悬挂，或者可以通过塑料注射成型过程制成。

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