专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009018477A3 METHODS OF INHIBITING CALCINEURIN WITH APOE ANALOGS 审中-公开
公开(公告)号：WO2009018477A3
公开(公告)日：2009-02-05
申请号：PCT/US2008/071815
申请日：2008-07-31
申请人： COGNOSCI, INC. , VITEK, Michael P. , LI, Feng-qiao
发明人： VITEK, Michael P. , LI, Feng-qiao
IPC分类号： C07K14/435 , C07K5/103 , A61K38/00
摘要： The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelinaton and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.

2. 发明申请

WO2009018477A2 METHODS OF INHIBITING CALCINEURIN WITH APOE ANALOGS 审中-公开
标题翻译：用阿片类似物抑制钙调素的方法
公开(公告)号：WO2009018477A2
公开(公告)日：2009-02-05
申请号：PCT/US2008071815
申请日：2008-07-31
申请人： COGNOSCI INC , VITEK MICHAEL P , LI FENG-QIAO
发明人： VITEK MICHAEL P , LI FENG-QIAO
IPC分类号： A61K38/10
CPC分类号： A61K38/1709 , C07K14/775
摘要： The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelinaton and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.
摘要翻译：本发明提供了通过使细胞与至少一种ApoE类似物接触来调节细胞中的钙调神经磷酸酶活性的方法。还公开了使用一种或多种ApoE类似物治疗与钙调神经磷酸酶活性相关的各种疾病的方法。特别地，本发明提供减少受试者的脱髓鞘和促进髓鞘再生的方法。还描述了在受试者中治疗脊髓或神经损伤的方法。

3. 发明授权

US07972182B2 Electrical connector with improved contact arrangement 有权
标题翻译：具有改进的接触布置的电连接器
公开(公告)号：US07972182B2
公开(公告)日：2011-07-05
申请号：US12955941
申请日：2010-11-30
申请人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
发明人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
IPC分类号： H01R24/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： An electrical connector has a receiving space (10) and includes an insulative housing (1) and a set of contacts. The insulative housing includes a tongue portion (12) protruding into the receiving space. The tongue portion has a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) defined in a rear region of the mating face and being spaced away from the depressions. The contacts are held in the tongue portion and include a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways and protruding beyond the mating face and into the receiving space, and first tail portions (16) opposite to the first contact portions. The second contacts have stiff second contact portions (25) retained in the depressions and exposed to the receiving space, and second tail portions (28) opposite to the second contact portions. The first and the second tail portions are arranged in only a single row.
摘要翻译：电连接器具有容纳空间（10）并且包括绝缘壳体（1）和一组触点。绝缘壳体包括突出到容纳空间中的舌部分（12）。舌部具有配合面（14），形成在配合面的前部区域中的一组凹部（141）和限定在配合面的后部区域中的一组通道（142）萧条。触点保持在舌部中并且包括一组第一和第二触点（21,22）。第一触点具有可移动地容纳在通道中的弹性第一接触部分（15），并突出超过配合面并进入接收空间，以及与第一接触部分相对的第一尾部（16）。第二触头具有保持在凹部中并暴露于容纳空间的刚性的第二接触部分（25）和与第二接触部分相对的第二尾部（28）。第一尾部和第二尾部仅排列成一排。

4. 发明申请

US20100261385A1 ELECTRICAL CONNECTOR WITH IMPROVED CONTACT ARRANGEMENT 有权
标题翻译：具有改进的触点布置的电气连接器
公开(公告)号：US20100261385A1
公开(公告)日：2010-10-14
申请号：US12825342
申请日：2010-06-29
申请人： QI-SHENG ZHENG , HAO GU , JIA-YONG HE , YU-LONG MAO , FENG QIAO
发明人： QI-SHENG ZHENG , HAO GU , JIA-YONG HE , YU-LONG MAO , FENG QIAO
IPC分类号： H01R13/648 , H01R24/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： An electrical connector for being mounted on a PCB, has a receiving space (10) and includes an insulative housing (1) having a tongue portion (12) being parallel to the PCB, the tongue portion having a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) formed in a rear region of the mating face; and a set of contacts including a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways, first tail portions (16), and first connecting portions (17) extending along the tongue portion. The second contacts have stiff second contact portions (25) received in the depressions, second tail portions (28), and second connecting portions (27) being parallel to the first connecting portions in a height direction of the tongue portion. The second contact portions (27) are located at an inner side of the mating face (14).
摘要翻译：一种用于安装在PCB上的电连接器，具有容纳空间（10）并且包括具有平行于PCB的舌部（12）的绝缘壳体（1），舌部具有配合面（14），形成在配合面的前部区域中的一组凹部（141）和形成在配合面的后部区域中的一组通路（142）以及一组触点，包括一组第一和第二触点（21,22）。第一触点具有可移动地容纳在通道中的弹性第一接触部分（15），第一尾部（16）和沿着舌部延伸的第一连接部分（17）。第二触点具有容纳在凹部中的刚性第二接触部分（25），第二尾部部分（28）和与舌部分的高度方向上的第一连接部分平行的第二连接部分（27）。第二接触部分（27）位于配合面（14）的内侧。

5. 发明授权

US07686656B2 Electrical connector with improved contacts 有权
标题翻译：具有改善触点的电连接器
公开(公告)号：US07686656B2
公开(公告)日：2010-03-30
申请号：US12228355
申请日：2008-08-11
申请人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
发明人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
IPC分类号： H01R24/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： An electrical connector includes an housing having a base portion, a tongue portion extending forwardly from the base portion and a number of passageways, the tongue portion defining a front face, a first side face and a second side face; a metal shell enclosing the tongue portion to define a receiving room therebetween, and defines a top wall, bottom wall and a pair of side walls, a first receiving room being formed between the bottom wall and the first side face; a number of contacts received in the passageways respectively and including a plurality of first contacts and second contacts, the first contacts each defining a first contacting portion, a first soldering portion and a first retaining portion, the second contacts each defining a second contacting portion, a second soldering portion and a second retaining portion. Both the second contacting portions and the first contacting portions are positioned on a same side of the second side face to be exposed to the first receiving room, the first contacting portions extend beyond the first side face.
摘要翻译：电连接器包括具有基部的壳体，从基部向前延伸的舌部和多个通道，舌部限定前表面，第一侧面和第二侧面; 包围所述舌部的金属外壳，以在其间限定接收室，并且限定顶壁，底壁和一对侧壁，在所述底壁和所述第一侧面之间形成第一容纳室; 多个触点分别容纳在通道中并且包括多个第一触点和第二触点，第一触头各限定第一接触部分，第一焊接部分和第一保持部分，第二触头各限定第二接触部分，第二焊接部分和第二保持部分。第二接触部分和第一接触部分都位于第二侧面的暴露于第一接收室的同一侧上，第一接触部分延伸超过第一侧面。

6. 发明申请

US20090315901A1 ELECTRONIC PAPER PANEL IMAGE UPDATE METHOD 审中-公开
标题翻译：电子纸板图像更新方法
公开(公告)号：US20090315901A1
公开(公告)日：2009-12-24
申请号：US12323334
申请日：2008-11-25
申请人： Feng Qiao , Pingfen Lin , Yuming Fang , Yang Zhou , Jingyu Liu
发明人： Feng Qiao , Pingfen Lin , Yuming Fang , Yang Zhou , Jingyu Liu
IPC分类号： G06T1/00
CPC分类号： G09G3/34 , G09G2310/04 , G09G2380/02
摘要： A updating method of images in electronic paper panel includes: divide the screen and image into (N*N) areas and build indexes for them; compare the present image on the display screen with the next image and compute the different areas; according to the computing result, find the uppermost, undermost, leftmost and rightmost different areas and compute the area of the smallest rectangle which includes the different areas; compare the result with the configured threshold and according to this compared result, set up the updating method to display the image. This method effectively reduces the data of updating images and save the power of the electronic paper, especially the power of the electronic paper panel. It can also improve the response time of the electronic paper panel. At the same time, it is easy to be ported to other advanced embedded operating systems. Thus, it could provide an effective method for the products related to the electronic paper.
摘要翻译：电子纸面板中的图像更新方法包括：将屏幕和图像划分为（N * N）个区域，为其构建索引; 将显示屏幕上的当前图像与下一图像进行比较，并计算不同的区域; 根据计算结果，找到最上，下，最左，最右的不同区域，并计算包括不同区域的最小矩形的面积; 将结果与配置的阈值进行比较，并根据此比较结果，设置更新方法来显示图像。该方法有效地减少了更新图像的数据，节省了电子纸的功率，特别是电子纸面板的功率。它还可以提高电子纸面板的响应时间。同时，很容易被移植到其他先进的嵌入式操作系统。因此，它可以为与电子纸相关的产品提供有效的方法。

7. 发明授权

US08629242B2 Methods of inhibiting calcineurin with ApoE analogs 有权
标题翻译：用ApoE类似物抑制钙调神经磷酸酶的方法
公开(公告)号：US08629242B2
公开(公告)日：2014-01-14
申请号：US12671433
申请日：2008-07-31
申请人： Michael P. Vitek , Feng-Qiao Li
发明人： Michael P. Vitek , Feng-Qiao Li
IPC分类号： C07K14/00
CPC分类号： A61K38/1709 , C07K14/775
摘要： The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelination and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.
摘要翻译：本发明提供了通过使细胞与至少一种ApoE类似物接触来调节细胞中的钙调神经磷酸酶活性的方法。还公开了使用一种或多种ApoE类似物治疗与钙调神经磷酸酶活性相关的各种疾病的方法。特别地，本发明提供减少受试者的脱髓鞘和促进髓鞘再生的方法。还描述了在受试者中治疗脊髓或神经损伤的方法。

8. 发明授权

US07744426B2 Electrical connector with improved contact arrangement 有权
标题翻译：具有改进的接触布置的电连接器
公开(公告)号：US07744426B2
公开(公告)日：2010-06-29
申请号：US12228388
申请日：2008-08-11
申请人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
发明人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
IPC分类号： H01R24/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： An electrical connector mounted on a mother PCB includes an insulative tongue portion and a number of contacts held in the insulative tongue portion. The contacts have four conductive contacts and at least one pair of differential contacts for transferring high speed signals. The conductive contacts are adapted for USB 2.0 protocol. The contacts include a plurality of first and second tail portions to be arranged in a single row or at least two rows.
摘要翻译：安装在母板上的电连接器包括绝缘舌部分和保持在绝缘舌部分中的多个触点。触点具有四个导电触点和用于传送高速信号的至少一对差动触点。导电触点适用于USB 2.0协议。触点包括多个第一尾部和第二尾部，以将它们排成一排或至少两排。

9. 发明申请

US20090042450A1 Electrical connector with improved contact arrangement 有权
标题翻译：具有改进接触布置的电连接器
公开(公告)号：US20090042450A1
公开(公告)日：2009-02-12
申请号：US12228388
申请日：2008-08-11
申请人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
发明人： Qi-Sheng Zheng , Hao Gu , Jia-Yong He , Yu-Long Mao , Feng Qiao
IPC分类号： H01R24/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： An electrical connector mounted on a mother PCB includes an insulative tongue portion and a number of contacts held in the insulative tongue portion. The contacts have four conductive contacts and at least one pair of differential contacts for transferring high speed signals. The conductive contacts are adapted for USB 2.0 protocol. The contacts include a plurality of first and second tail portions to be arranged in a single row or at least two rows.
摘要翻译：安装在母板上的电连接器包括绝缘舌部分和保持在绝缘舌部分中的多个触点。触点具有四个导电触点和用于传送高速信号的至少一对差动触点。导电触点适用于USB 2.0协议。触点包括多个第一尾部和第二尾部，以将它们排成一排或至少两排。

10. 发明申请

US20090042448A1 Stacked electrical connector with improved signal transmission 有权
公开(公告)号：US20090042448A1
公开(公告)日：2009-02-12
申请号：US12228390
申请日：2008-08-11
申请人： Jia-Yong He , Qi-Sheng Zheng , Hao Gu , Yu-Long Mao , Feng Qiao
发明人： Jia-Yong He , Qi-Sheng Zheng , Hao Gu , Yu-Long Mao , Feng Qiao
IPC分类号： H01R27/00
CPC分类号： H01R12/712 , H01R13/658 , H01R24/62 , H01R2107/00
摘要： A stacked electrical connector includes a first mating interface. The first mating interface comprises a first receiving space (101) with a first tongue (102). The first tongue (102) has a pair of upper and lower face (1021, 1022). A plurality of first contacts (20) are retained in the first mating interface. The first contacts (20) include a plurality of first elastic contacts (201) and a plurality of first flat contact (202). Each first elastic contact (201) has a securing portion (2011) fixed in the first mating interface (101), an elastic contact portion (2010) extending to the first tongue (102) and a soldering portion (2012). Each first flat contact (202) has a retention portion (2024, 2028) retained in the first mating interface (101), a flat contact portion (2022, 2026) extending to the first tongue (102) and a tail portion (2025, 2029). The flat contact portions (2022, 2026) and the elastic contact portions (2010) are located at a same side of the upper face (1021), and are arranged in two rows along a length direction of the first tongue (102). A second mating interface is stacked with the first mating interface along a thickness direction of the first tongue (102). A plurality of second contacts (21) are retained in the second mating interface.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式