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1. 发明申请

WO1996005877A1 METHOD OF STERILIZING PREFILLED SYRINGE MEDICINES 审中-公开
标题翻译：灭菌注射液药物灭菌方法
公开(公告)号：WO1996005877A1
公开(公告)日：1996-02-29
申请号：PCT/JP1995001644
申请日：1995-08-21
申请人： EIKEN CHEMICAL CO., LTD. , MATSUMOTO, Yasuyuki , SAITO, Masahiro , MORIKAWA, Junji , TAKANO, Hiroshi
发明人： EIKEN CHEMICAL CO., LTD.
IPC分类号： A61M05/31
CPC分类号： A61L2/06 , A61L2/26 , A61M5/001
摘要： The invention provides a method of sterilizing a chemical and an injector in a prefilled syringe and keeping them in sterilized condition, said method comprising mounting a liquid leakage preventive cap (1) on a tip end of an injector (2) in a prefilled syringe, filled with a chemical and mounting a sliding plug (3) in an opening at a rear end of the injector to prevent liquid leakage of the prefilled syringe, securing the prefilled syringe, which mounts thereto the liquid leakage preventive cap (1) and the sliding plug (3), by means of a securing container (6), sealing the securing container (6), to which the prefilled syringe (2) is fixed, by means of a poromeric and bacteria impermeable nonwoven paper or fabric to sterilize a chemical (5) in the prefilled syringe (2), the prefilled syringe (2) and the securing container at the same time. The securing container (6) is enclosed by a bag-shaped nonwoven paper or fabric (7). Alternatively, the securing container (6) may have an opening, and the opening may be sealed by the nonwoven paper or fabric (11). According to the invention, it is possible to manufacture a prefilled syringe kit readily at low cost in a sterilized manner and keep the sterilized condition.
摘要翻译：本发明提供了一种在预充式注射器中对化学药剂和注射器进行灭菌并将其保持在灭菌状态的方法，所述方法包括将防漏液帽（1）安装在预充式注射器中的注射器（2）的末端上，填充有化学品并将滑动塞（3）安装在喷射器后端的开口中，以防止预填充的注射器的液体泄漏，固定预充式注射器，该注射器安装在防漏液盖（1）上并滑动通过固定容器（6）将塞子（3），借助于通孔和细菌不可渗透的非织造纸或织物将固定的预充式注射器（2）固定到其上的固定容器（6）进行灭菌（5）在预充式注射器（2）中，预充式注射器（2）和固定容器同时进行。固定容器（6）由袋状非织造纸或织物（7）包围。或者，固定容器（6）可以具有开口，并且开口可以被非织造纸或织物（11）密封。根据本发明，可以以无菌方式以低成本容易地制造预填充注射器套件并保持灭菌状态。

2. 发明专利

AU2004280430B2 Primer for detecting Alicyclobacillus 未知
公开(公告)号：AU2004280430B2
公开(公告)日：2008-03-13
申请号：AU2004280430
申请日：2004-10-08
申请人： EIKEN CHEMICAL CO LTD , SAPPORO BREWERIES
发明人： OGAWA MASAHIRO , TSUCHIYA YOUICHI , NAKAKITA YASUKAZU
IPC分类号： C12N15/09 , C12Q1/68
摘要： Primers specific for an Alicyclobacillus spp. are used to amplify specific regions of 16S rDNA gene of the Alicyclobacillus spp., and the presence or absence of the amplified product is confirmed to detect the Alicyclobacillus spp. (especially Alicyclobacillus acidoterrestris).

3. 发明专利

DE3128415C2 未知
公开(公告)号：DE3128415C2
公开(公告)日：1985-05-30
申请号：DE3128415
申请日：1981-07-17
申请人： EIKEN CHEMICAL CO., LTD., TOKIO/TOKYO, JP
发明人： IIDA, TAMOTSU, OYAMA, TOCHIGIN, JP , ENOMOTO, SEIJI, SAITAMA, JP , KIMURA, MICHIYA, OYAMA, TOCHIGI, JP
IPC分类号： C12M1/34 , C12M1/20 , C12Q1/04
摘要： A tray has a cover and a plastics or glass body divided by transverse partitions into cells. Each cell is dived by a barrier with its top lower than the partition into a well for bacterial suspension and a second well. The barrier slope up from the first cell at a low gradient to the barrier top and then falls abruptly as the side of the second well. Each second well pref. has two shallow recesses in its base to hold growth media components. The partitions are pref. 2 mm lower than the peripheral wall and the cover has outwardly diverging vent passages. The arrangement facilitates pouring of suspension and prevents backflow from the second cells.

4. 发明专利

AU2008313042B2 Method of stabilizing hem protein and storage solution therefor 未知
公开(公告)号：AU2008313042B2
公开(公告)日：2014-05-01
申请号：AU2008313042
申请日：2008-10-06
申请人： EIKEN CHEMICAL CO LTD
发明人： SUGO SHIN
IPC分类号： G01N33/531 , G01N1/28 , G01N33/48 , G01N33/72
摘要： [PROBLEMS] To provide a method of stabilizing a hem protein which is effective against the denaturation and degradation of a hem protein typified by hemoglobin and a storage solution therefor. [MEANS FOR SOLVING PROBLEMS] A method of stabilizing a hem protein and a storage solution therefor characterized in that an iminocarboxylic acid or its salt is made to coexist in a sample containing the hem protein, wherein the above-described iminocarboxylic acid is a compound represented by the following general formula (1) wherein R represents a hydrogen atom or a hydroxyl group; and X's represent each a hydrogen atom, an alkali metal or an ammonium group.

5. 发明专利

DE3040005C2 未知
公开(公告)号：DE3040005C2
公开(公告)日：1982-12-30
申请号：DE3040005
申请日：1980-10-23
申请人： EIKEN CHEMICAL CO., LTD., TOKYO, JP
发明人： TERANISHI, HYROYASU, TOYKO, JP
IPC分类号： C12N9/96 , C12Q1/00

6. 发明专利

DE3029149C2 未知
公开(公告)号：DE3029149C2
公开(公告)日：1982-12-09
申请号：DE3029149
申请日：1980-07-31
申请人： EIKEN CHEMICAL CO., LTD., TOKYO, JP
发明人： MASAKI, TOSHIKATSU, NIIZA, SAITAMA, JP , ENOMOTO, SEIJI, SAITAMA, JP , KIMURA, MICHIYA, OYAMA, TOCHIGI, JP
IPC分类号： C12M1/34 , C12M1/18 , C12M1/20 , C12Q1/08
摘要： A tray for identifying isolated microorganisms consisting of a plastic or glass tray body and a transparent cover, the body surface of which has two kinds of hollows for bacterial suspensions. One is formed horizontally across the surface of the tray and the other is composed of number of small wells long and slender, put parallel and rectangular to previous hollow. Each of the small cells communicates over crest barrier to hollow put horizontally. With this tray, microorganisms can be exactly and easily identified.

7. 发明授权

EP2204648B1 METHOD OF STABILIZING HEM PROTEIN AND STORAGE SOLUTION THEREFOR 失效
标题翻译：方法用于稳定血红素蛋白和存储解决方案THEREFOR
公开(公告)号：EP2204648B1
公开(公告)日：2016-11-30
申请号：EP08840474.4
申请日：2008-10-06
申请人： Eiken Chemical Co., Ltd.
发明人： SUGO, Shin
IPC分类号： G01N33/531 , G01N1/28 , G01N33/48 , G01N33/72 , C07C229/00
CPC分类号： G01N33/721 , C07C229/24 , G01N33/80 , Y10T436/108331

8. 发明授权

EP2944959B1 HEMOGLOBIN STABILIZING STORAGE SOLUTION 失效
标题翻译：血红蛋白稳定化存储解决方案
公开(公告)号：EP2944959B1
公开(公告)日：2016-11-30
申请号：EP15174423.2
申请日：2008-10-06
申请人： Eiken Chemical Co., Ltd.
发明人： SUGO, Shin
IPC分类号： G01N33/531 , G01N1/28 , G01N33/48 , G01N33/72 , C07C229/00
CPC分类号： G01N33/721 , C07C229/24 , G01N33/80 , Y10T436/108331

9. 发明公开

EP2204648A1 METHOD OF STABILIZING HEM PROTEIN AND STORAGE SOLUTION THEREFOR 失效
标题翻译： VERFAHREN ZUR STABILISIERUNG VONHÄM-PROTEIN UNDLAGERUNGSLÖSUNGDAFÜR
公开(公告)号：EP2204648A1
公开(公告)日：2010-07-07
申请号：EP08840474.4
申请日：2008-10-06
申请人： Eiken Chemical Co., Ltd.
发明人： SUGO, Shin, c/o Eiken Chemical Co.,Ltd
IPC分类号： G01N33/531 , G01N1/28 , G01N33/48 , G01N33/72
CPC分类号： G01N33/721 , C07C229/24 , G01N33/80 , Y10T436/108331
摘要： There is provided a novel method of stabilizing a heme protein, which is effective against denaturation and degradation of a heme protein such as hemoglobin. A method of stabilizing a heme protein comprises allowing an iminocarboxylic acid or a salt thereof to coexist in a sample containing the heme protein. In the method, the iminocarboxylic acid or a salt thereof is preferably a compound of Formula (1):

in which R is a hydrogen atom or a hydroxy group, and X is a hydrogen atom, an alkali metal, or an ammonium group), or a mixture thereof. A storage solution for a heme protein comprises the iminocarboxylic acid or a salt thereof.
摘要翻译：提供了稳定血红素蛋白质的新方法，其有效地抗血红素蛋白质如血红蛋白的变性和降解。稳定血红素蛋白质的方法包括使亚氨基羧酸或其盐共存在含有血红素蛋白质的样品中。在该方法中，亚氨基羧酸或其盐优选为式（1）的化合物：其中R为氢原子或羟基，X为氢原子，碱金属或铵基团），或其混合物。血红素蛋白质的储存溶液包含亚氨基羧酸或其盐。

10. 发明公开

EP1672081A1 PRIMER FOR DETECTING ALICYCLOBACILLUS 审中-公开
标题翻译： PRIMER ZUM NACHWEIS VON ALICYCLOBACILLUS
公开(公告)号：EP1672081A1
公开(公告)日：2006-06-21
申请号：EP04792227.3
申请日：2004-10-08
申请人： Sapporo Breweries Limited , Eiken Chemical Co., Ltd.
发明人： Nakakita, Yasukazu, Sapporo Breweries Limited , Ogawa, Masahiro, Sapporo Breweries Limited , Tsuchiya, Youichi, Sapporo Breweries Limited
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/6844 , C12Q2600/16
摘要： Primers specific for an Alicyclobacillus spp. are used to amplify specific regions of 16S rDNA gene of the Alicyclobacillus spp., and the presence or absence of the amplified product is confirmed to detect the Alicyclobacillus spp. (especially Alicyclobacillus acidoterrestris).
摘要翻译：对脂环芽孢杆菌属特异性的引物用于扩增脂环酸杆菌属的16S rDNA基因的特异性区域，确认扩增产物的存在或不存在以检测脂环酸杆菌属。（尤其是酸性脂环酸杆菌）。

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