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1. 发明申请

WO2009013692A2 MULTIMODALITY MATCHING MEDIUM FOR DIFFUSE OPTICAL TOMOGRAPHY AND ULTRASOUND MEASUREMENTS 审中-公开
标题翻译：用于弥散性光学造影和超声波测量的多功能匹配介质
公开(公告)号：WO2009013692A2
公开(公告)日：2009-01-29
申请号：PCT/IB2008/052910
申请日：2008-07-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN DER MARK, Martinus, B , ENTREKIN, Robert, R. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , VAN DER VAART, Nijs, C.
发明人： VAN DER MARK, Martinus, B , ENTREKIN, Robert, R. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , VAN DER VAART, Nijs, C.
IPC分类号： A61B5/00 , A61B8/08 , A61K49/22 , G01N21/17 , G01N21/47 , G01N21/49 , G01N29/24 , G01N29/28
CPC分类号： A61K49/0002 , A61B5/0035 , A61B5/0091 , A61B5/4312 , A61B8/0825 , A61B8/4272 , A61B8/429 , A61B8/4416 , A61B2562/146 , A61K49/226
摘要： The invention relates to a matching medium that is used to optically couple an optically turbid medium to its surroundings during diffuse optical tomography measurements. Generally, an optical matching medium makes it hard to acoustically couple the turbid medium to its surroundings efficiently. According to the invention, this problem is solved by using a matching medium that matches both the optical and acoustic characteristics of the turbid medium to the optical and acoustic characteristics of the surroundings of the turbid medium. The invention explains how a multimodality matching medium can be obtained that both optically and acoustically couples human tissue to its surroundings.
摘要翻译：本发明涉及一种匹配介质，其用于在漫射光学层析成像测量期间将光学混浊介质光学耦合到其周围环境。通常，光学匹配介质使得难以有效地将混浊介质与其周围环境耦合。根据本发明，通过使用与混浊介质的光学和声学特性匹配的匹配介质与混浊介质周围的光学和声学特性相匹配来解决该问题。本发明解释了如何获得将人体组织光学和声学耦合到其周围环境的多模式匹配介质。

2. 发明申请

WO2005122904A1 A TRANSDUCER UNIT INCORPORATING AN ACOUSTIC COUPLER 审中-公开
标题翻译：一个兼容声学耦合器的变压器单元
公开(公告)号：WO2005122904A1
公开(公告)日：2005-12-29
申请号：PCT/IB2005/051900
申请日：2005-06-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ENTREKIN, Robert
发明人： ENTREKIN, Robert
IPC分类号： A61B8/00
CPC分类号： A61B8/4455 , A61B8/0825 , A61B8/4209 , A61B8/4281
摘要： The present invention relates to a transducer unit for an ultrasonic breast imaging system, in which an acoustic coupler is employed which comprises a frame in which a transducer is mounted. The frame is open at one end, and a surface of the transducer is exposed at the open end. The frame and exposed transducer surface are put under compression against the surface of a compression plate with a gasket, or similar, providing a fluid-tight seal therebetween. A thin layer of acoustic couplant is provided between the transducer surface and the compression plate. The frame defines a chamber around the nonexposed surface of the transducer, the chamber housing an acoustic couplant.
摘要翻译：本发明涉及一种用于超声乳房成像系统的换能器单元，其中采用声耦合器，其包括安装换能器的框架。框架在一端打开，传感器的表面在开口端露出。框架和暴露的换能器表面被压在压缩板的表面上，垫圈或类似物在其间提供流体密封的密封。在传感器表面和压缩板之间提供薄层的声耦合剂。框架围绕换能器的未暴露的表面限定一个腔室，该腔室容纳声学耦合剂。

3. 发明申请

WO2009147620A2 EXTENDED FIELD OF VIEW ULTRASONIC IMAGING WITH A TWO DIMENSIONAL ARRAY PROBE 审中-公开
标题翻译：扩展视野超声波成像与两维阵列探测
公开(公告)号：WO2009147620A2
公开(公告)日：2009-12-10
申请号：PCT/IB2009/052321
申请日：2009-06-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , YOO, Yangmo , JAGO, James , JONG, Jing-Ming , ENTREKIN, Robert , ANDERSON, Martin , OLSSON, Lars, Jonas
发明人： YOO, Yangmo , JAGO, James , JONG, Jing-Ming , ENTREKIN, Robert , ANDERSON, Martin , OLSSON, Lars, Jonas
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/5205 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The display format may be either a 2D EFOV image or a 3D EFOV image.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个取向中获取的一系列图像。显示格式可以是2D EFOV图像或3D EFOV图像。

4. 发明申请

WO2009027890A1 DUAL PATH COLOR DOPPLER IMAGING SYSTEM AND METHOD FOR SIMULTANEOUS INVASIVE DEVICE VISUALIZATION AND VASCULATURE IMAGING 审中-公开
标题翻译：双路彩色多普勒成像系统及同步入侵设备可视化和血管成像的方法
公开(公告)号：WO2009027890A1
公开(公告)日：2009-03-05
申请号：PCT/IB2008/053270
申请日：2008-08-14
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , GAUTHIER, Thomas , CRITON, Aline , BRUCE, Matthew , ENTREKIN, Robert , POWERS, Jeffry, E.
发明人： GAUTHIER, Thomas , CRITON, Aline , BRUCE, Matthew , ENTREKIN, Robert , POWERS, Jeffry, E.
IPC分类号： A61B8/08 , A61B8/06 , G01S15/89 , A61B17/34
CPC分类号： G01S15/8979 , A61B8/06 , A61B8/0833 , A61B8/0841 , A61B8/13 , A61B8/488 , A61B2017/3413 , G01S7/52026 , G01S7/52084
摘要： An ultrasound imaging system (10) is disclosed for creating simultaneous needle and vascular blood flow color Doppler imaging. A B mode image of an anatomical area of interest is created. A first set of Doppler image data optimized for the visualization of vascular blood flow is created along one Doppler image processing path. A second set of Doppler image data optimized for the visualization of a needle or other invasive device is created along another, parallel Doppler image processing path. A color Doppler image is created, and then displayed, by combining some or all of the B mode image, the first Doppler image data and the second Doppler image data based on a plurality of user selectable modes.
摘要翻译：公开了一种用于创建同时针和血管血流彩色多普勒成像的超声成像系统（10）。创建感兴趣的解剖区域的B模式图像。沿着一个多普勒图像处理路径创建针对血管血流可视化优化的第一组多普勒图像数据。沿着另一个并行的多普勒图像处理路径创建针对针或其他侵入性设备的可视化优化的第二组多普勒图像数据。通过基于多个用户可选择模式组合B模式图像，第一多普勒图像数据和第二多普勒图像数据中的一些或全部来创建彩色多普勒图像，然后显示。

5. 发明申请

WO2008146195A3 DEVICE FOR IMAGING AN INTERIOR OF AN OPTICALLY TURBID MEDIUM USING DIFFUSE OPTICAL TOMOGRAPHY AND ULTRASOUND 审中-公开
标题翻译：用于成像使用DIFFUSE OPTICAL TOMOGRAPHY和ULTRASOUND的光学涡卷介质内部的装置
公开(公告)号：WO2008146195A3
公开(公告)日：2009-01-29
申请号：PCT/IB2008051958
申请日：2008-05-19
申请人： KONINKL PHILIPS ELECTRONICS NV , ENTREKIN ROBERT R , VAN DER MARK MARTINUS B , VAN BEEK MICHAEL C , BAKKER LEVINUS P , COMPEN HENDRIKUS A C M , DEHN FRANK , VAN DER VAART NIJS C , DECKERS JACOBUS A J M , SUIJVER JAN F
发明人： ENTREKIN ROBERT R , VAN DER MARK MARTINUS B , VAN BEEK MICHAEL C , BAKKER LEVINUS P , COMPEN HENDRIKUS A C M , DEHN FRANK , VAN DER VAART NIJS C , DECKERS JACOBUS A J M , SUIJVER JAN F
IPC分类号： A61B5/00 , A61B8/08
CPC分类号： A61B5/4312 , A61B5/0073 , A61B5/0091 , A61B8/0825 , A61B8/5238
摘要： The invention relates to a device for imaging the interior of a volume of an object using diffuse optical tomography and ultrasound. According to the invention a volume in which the object is accommodated and into which optical and ultrasound signals are sent is bound by a wall structure comprising entrance and exit positions for both the optical and ultrasound signals. In this way, the object can be positioned relative to the wall structure resulting in a well-defined measurement geometry. The invention improves the comparability of scans of an object that have been made at different points in time as the positioning of the object in a first scan can be precisely reproduced in a further scan relative to the wall structure.
摘要翻译：本发明涉及一种使用漫射光学层析成像和超声波成像物体体积内部的装置。根据本发明，其中容纳物体并且发送光学和超声信号的体积被包括光学和超声信号两者的入射和出射位置的壁结构所约束。以这种方式，物体可以相对于壁结构定位，从而产生明确的测量几何形状。本发明改进了在不同时间点进行的物体的扫描的可比性，因为可以在相对于墙壁结构的进一步扫描中精确地再现第一扫描中的物体的定位。

6. 发明申请

WO2011064688A1 ULTRASONIC SHEAR WAVE IMAGING WITH FOCUSED SCANLINE BEAMFORMING 审中-公开
标题翻译：超声剪切波成像与聚焦扫描光束
公开(公告)号：WO2011064688A1
公开(公告)日：2011-06-03
申请号：PCT/IB2010/055179
申请日：2010-11-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PETERSON, Roy, B. , SHAMDASANI, Vijay , ENTREKIN, Robert, Randall , SHI, Yan , XIE, Hua , ROBERT, Jean-luc
发明人： PETERSON, Roy, B. , SHAMDASANI, Vijay , ENTREKIN, Robert, Randall , SHI, Yan , XIE, Hua , ROBERT, Jean-luc
IPC分类号： G01S7/52 , A61B8/08 , G01N29/34 , G01N29/07
CPC分类号： A61B8/485 , A61B5/0048 , A61B8/08 , A61B8/085 , A61B8/14 , A61B8/463 , A61B8/5223 , G01S7/52022 , G01S7/52042 , G01S7/52071 , G01S7/52095 , G01S15/8984
摘要： An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color- coded and displayed over an anatomical image of the region of interest.
摘要翻译：超声波诊断成像系统通过传递推动脉冲来产生剪切波速度的图像以产生剪切波。多个跟踪线被发送，并且由聚焦波束形成器接收的与推送脉冲位置相邻的回波。跟踪线以时间交织的方式进行采样。处理沿着每个跟踪线获取的回波数据，以确定由沿着跟踪线的点处的剪切波引起的峰组织位移的时间，以及相邻跟踪线的峰值时间，以计算局部剪切波速度。所得到的剪切波速度值的图被颜色编码并显示在感兴趣区域的解剖图像上。

7. 发明申请

WO2009147621A2 EXTENDED FIELD OF VIEW ULTRASONIC IMAGING WITH GUIDED EFOV SCANNING 审中-公开
标题翻译：扩展视野超声波成像与指导EFOV扫描
公开(公告)号：WO2009147621A2
公开(公告)日：2009-12-10
申请号：PCT/IB2009/052322
申请日：2009-06-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , YOO, Yangmo , JAGO, James , JONG, Jing-Ming , ENTREKIN, Robert , OLSSON, Lars, Jonas
发明人： YOO, Yangmo , JAGO, James , JONG, Jing-Ming , ENTREKIN, Robert , OLSSON, Lars, Jonas
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The motion estimates are also used to display a graphic on the display screen which indicates the progress of the scan to the user as the probe is being moved. The progress may be indicated in terms of probe velocity, distance traveled, or the path traversed by the moving probe.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个取向中获取的一系列图像。运动估计还用于在显示屏幕上显示图形，其指示当移动探针时向用户扫描的进展。可以根据探头速度，行进距离或移动探头穿过的路径来指示进度。

8. 发明申请

WO2009010901A1 ULTRASOUND PROBE WITH COUPLED DEGREES OF FREEDOM AND DEVICE COMPRISING SUCH ULTRASOUND PROBE 审中-公开
标题翻译：具有自由联合度的超声波探头和包含这样的超声波探头的装置
公开(公告)号：WO2009010901A1
公开(公告)日：2009-01-22
申请号：PCT/IB2008/052756
申请日：2008-07-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN DER MARK, Martinus, B. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , ENTREKIN, Robert, R.
发明人： VAN DER MARK, Martinus, B. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , ENTREKIN, Robert, R.
IPC分类号： G01S15/89
CPC分类号： G01S15/894 , G01S7/52085 , G01S15/8918 , G01S15/8927
摘要： The invention relates to an ultrasound probe having various degrees of freedom such as the width of the ultrasound beam generated by the probe and translation and rotation of the probe. By coupling the control of one degree of freedom to the control of a further degree of freedom, the ultrasound beam can be made to precisely follow the contours of volumes having various shapes.
摘要翻译：本发明涉及具有各种自由度的超声波探头，例如由探头产生的超声波束的宽度和探头的平移和旋转。通过将一个自由度的控制耦合到另一自由度的控制，可以使超声波束精确地跟随具有各种形状的体积轮廓。

9. 发明申请

WO2006064470A3 METHOD AND APPARATUS FOR AUTOMATICALLY DEVELOPING A HIGH PERFORMANCE CLASSIFIER FOR PRODUCING MEDICALLY MEANINGFUL DESCRIPTORS IN MEDICAL DIAGNOSIS IMAGING 审中-公开
标题翻译：用于自动开发用于在医学诊断成像中生产医学意义描述符的高性能分类器的方法和装置
公开(公告)号：WO2006064470A3
公开(公告)日：2006-10-05
申请号：PCT/IB2005054220
申请日：2005-12-13
申请人： KONINKL PHILIPS ELECTRONICS NV , SCHAFFER JAMES DAVID , ALI WALID , ESHELMAN LARRY J , COHEN-BACRIE CLAUDE , LAGRANGE JEAN-MICHEL , LEVRIER CLAIRE , VILLAIN NICHOLAS , ENTREKIN ROBERT R
发明人： SCHAFFER JAMES DAVID , ALI WALID , ESHELMAN LARRY J , COHEN-BACRIE CLAUDE , LAGRANGE JEAN-MICHEL , LEVRIER CLAIRE , VILLAIN NICHOLAS , ENTREKIN ROBERT R
IPC分类号： G06K9/62
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images are determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid- level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集合。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

10. 发明申请

WO2003093862A1 ULTRASOUND IMAGING SYSTEM WITH A HIGH LATERAL RESOLUTION 审中-公开
标题翻译：超高分辨率超声波成像系统
公开(公告)号：WO2003093862A1
公开(公告)日：2003-11-13
申请号：PCT/IB2003/001587
申请日：2003-04-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LEVRIER, Claire , COHEN-BACRIE, Claude , VILLAIN, Nicolas , LAGRANGE, Jean-Michel , ENTREKIN, Robert
发明人： LEVRIER, Claire , COHEN-BACRIE, Claude , VILLAIN, Nicolas , LAGRANGE, Jean-Michel , ENTREKIN, Robert
IPC分类号： G01S7/52
CPC分类号： G01S7/52049 , G01S15/8977 , G01S15/8995
摘要： The invention relates to an ultrasound imaging system for forming an echographic image of a medium, which system includes a set [REC] of transducer elements [EL] which are operative in a transmission mode and in a reception mode for ultrasound waves, construction means [REB] for constructing echographic signals on the basis of signals [S[1] ... S[N]] received on said transducer elements [EL], display means [DIS] which are coupled to said construction means [REB] in order to display an image of the medium formed by means of the echographic signals. Said construction means [REB] are such that in so-called exclusion zones, in which a coherent reflector is detected and which are determined by determination means [DET], the reception delays [D] are estimated in a manner [INT] other than that [CORR] used for the other zones. The calculation [CAL] of echographic signals is then carried out on the basis of said estimated delays [D[Z],Di[Z]]. The invention enables a correction of phase aberrations and nevertheless offers an excellent lateral resolution, notably in the case of point coherent reflectors.
摘要翻译：本发明涉及一种用于形成介质的回波图像的超声波成像系统，该系统包括以传输模式和超声波接收模式操作的换能器元件[EL]的组[REC]，构造装置[ REB]，用于根据在所述换能器元件[EL]上接收的信号[S [1] ... S [N]]构成回波信号，依次耦合到所述构造装置[REB]的显示装置[DIS] 以显示通过回波信号形成的介质的图像。所述构造装置[REB]使得在所谓的排除区域中，其中检测到相干反射器并且由确定装置[DET]确定，所述接收延迟[D]以除[ [CORR]用于其他区域。然后基于所述估计的延迟[D [Z]，Di [Z]]执行回波成像信号的计算[CAL]。本发明能够校正相位差，并且提供优异的横向分辨率，特别是在点相干反射器的情况下。

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