专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20040258758A1 Nanoparticulate topiramate formulations 有权
标题翻译：纳米微丸托吡酯配方
公开(公告)号：US20040258758A1
公开(公告)日：2004-12-23
申请号：US10766960
申请日：2004-01-30
申请人： Elan Pharma International, Ltd.
发明人： Evan Gustow , Tuula Ryde , Eugene R. Cooper
IPC分类号： A61K009/14
CPC分类号： A61K31/7048 , A61K9/145 , A61K9/146
摘要： The present invention is directed to nanoparticulate compositions comprising topiramate. The topiramate particles of the composition have an effective average particle size of less than about 2 microns.
摘要翻译：本发明涉及包含托吡酯的纳米颗粒组合物。组合物的托吡酯颗粒具有小于约2微米的有效平均粒度。

2. 发明申请

US20040258757A1 Liquid dosage compositions of stable nanoparticulate active agents 审中-公开
标题翻译：稳定的纳米颗粒活性剂的液体剂量组合物
公开(公告)号：US20040258757A1
公开(公告)日：2004-12-23
申请号：US10619539
申请日：2003-07-16
申请人： Elan Pharma International, Ltd.
发明人： H. William Bosch , Matthew R. Hilborn , Douglas C. Hovey , Laura J. Kline , Robert W. Lee , John D. Pruitt , Niels P. Ryde , Tuula A. Ryde , Shuqian Xu
IPC分类号： A61K009/14
CPC分类号： A61K9/0095 , A61K9/143 , A61K9/145 , A61K9/146 , A61K31/192 , A61K31/57 , A61K31/573 , A61K31/58
摘要： The present invention relates to liquid dosage compositions of stable nanoparticulate active agents. The liquid dosage compositions of the invention include osmotically active crystal growth inhibitors that stabilize the nanoparticulate active agents against crystal and particle size growth of the active agent.
摘要翻译：本发明涉及稳定的纳米颗粒活性剂的液体剂量组合物。本发明的液体剂量组合物包括渗透活性晶体生长抑制剂，其稳定纳米颗粒活性剂以防止活性剂的晶体和粒度增长。

3. 发明申请

US20040156895A1 Solid dosage forms comprising pullulan 审中-公开
标题翻译：包含支链淀粉的固体剂型
公开(公告)号：US20040156895A1
公开(公告)日：2004-08-12
申请号：US10705227
申请日：2003-11-12
申请人： Elan Pharma International Ltd.
发明人： John D. Pruitt , Douglas C. Hovey , Tuula A. Ryde , H. William Bosch , Robert W. Lee
IPC分类号： A61K031/715 , A61K009/20
CPC分类号： A61K9/2095 , A61K9/0056 , A61K9/146 , A61K9/2018 , A61K9/205 , A61K9/2081 , A61K31/00 , A61K31/192
摘要： Disclosed are solid dosage forms of active agents and pullulan. The solid dosage form has a friability of less than about 1%.
摘要翻译：公开了活性剂和支链淀粉的固体剂型。固体剂型具有小于约1％的脆性。

4. 发明申请

US20040141925A1 Novel triamcinolone compositions 审中-公开
标题翻译：新型曲安奈德组合物
公开(公告)号：US20040141925A1
公开(公告)日：2004-07-22
申请号：US10697716
申请日：2003-10-31
申请人： Elan Pharma International Ltd.
发明人： H. William Bosch , Kevin D. Ostrander , Eugene R. Cooper
IPC分类号： A61L009/04 , A61K009/14
CPC分类号： B82Y5/00 , A01N25/12 , A01N25/24 , A01N25/30 , A61K9/145 , A61K9/146 , A61K31/192 , A61K31/57 , A61K31/58 , A61K47/6929
摘要： The invention is directed to nanoparticulate triamcinolone and/or triamcinolone derivative compositions. The triamcinolone or triamcinolone derivative particles of the composition have an effective average particle size of less than about 2 microns.
摘要翻译：本发明涉及纳米颗粒曲安奈德和/或曲安奈德衍生物组合物。组合物的曲安奈德或曲安奈德衍生物颗粒具有小于约2微米的有效平均粒度。

5. 发明申请

US20040058009A1 Nanoparticulate fibrate formulations 有权
标题翻译：纳米颗粒贝特类制剂
公开(公告)号：US20040058009A1
公开(公告)日：2004-03-25
申请号：US10692855
申请日：2003-10-27
申请人： Elan Pharma International, Ltd.
发明人： Tuula Ryde , Evan E. Gustow , Stephen B. Ruddy , Rajeev Jain , Rakesh Patel , Michael John Wilkins
IPC分类号： A61K009/16 , A61K009/50
CPC分类号： A61K31/19 , A61K9/145 , A61K9/146 , A61K9/2077 , A61K31/14 , A61K31/216 , A61K45/06 , Y10T428/29 , A61K2300/00
摘要： The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.
摘要翻译：本发明涉及具有改善的药代动力学特征和降低的进食/禁食变异性的贝特类组合物。组合物的贝特类颗粒具有小于约2000nm的有效平均粒度。

6. 发明授权

US09351902B2 Method and device for scar management 有权
标题翻译：疤痕治疗方法和装置
公开(公告)号：US09351902B2
公开(公告)日：2016-05-31
申请号：US14464443
申请日：2014-08-20
申请人： Elan Pharma International Ltd.
发明人： Jessica Rowen
IPC分类号： A61H15/00 , A61M35/00 , A61H15/02 , A45D34/04 , A61H23/00 , A61K31/695 , A61K31/80
CPC分类号： A61H15/02 , A45D34/041 , A61H15/0092 , A61H23/00 , A61H2015/0064 , A61H2201/105 , A61K8/0216 , A61K8/585 , A61K8/891 , A61K8/892 , A61K8/895 , A61K31/695 , A61K31/80 , A61K2800/596 , A61K2800/874 , A61M35/003 , A61M39/22 , A61M2205/19 , A61Q17/04 , A61Q19/00
摘要： A device for scar management includes an applicator head including a recess having a rotating means therein, a reservoir containing a silicone composition fluidly connected to the applicator head, and a metering valve fluidly connected to the reservoir. The composition has viscosity of 3,000 to 8,000 cps, and consists of a mixture of cyclopentasiloxane, dimethiconol, dimethicone, and dimethicone/vinyl dimethicone crosspolymer. A metered dose of the silicone composition is delivered from the reservoir to the applicator head upon the application of external pressure to the metering valve. The invention also relates to a method for scar management using such device by identifying a target skin area having a wound or scar, contacting the outward surface of the applicator head to the target skin area, massaging the rotating means of the applicator head on the target skin area, and applying the silicone composition to the target skin area via the rotating means.
摘要翻译：一种用于瘢痕管理的装置包括：涂抹器头，包括其中具有旋转装置的凹部，包含流体连接到涂抹头的硅氧烷组合物的储存器和流体连接到储存器的计量阀。该组合物具有3,000至8,000cps的粘度，并且由环戊硅氧烷，聚二甲基硅氧烷醇，聚二甲基硅氧烷和聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物的混合物组成。在对计量阀施加外部压力时，计量剂量的硅氧烷组合物从储存器输送到施用器头部。本发明还涉及一种通过识别具有伤口或疤痕的目标皮肤区域使用这种装置的瘢痕管理方法，其将涂抹器头部的外表面接触到目标皮肤区域，按摩目标上的涂抹器头部的旋转装置皮肤区域，并且经由旋转装置将硅氧烷组合物施加到目标皮肤区域。

7. 发明申请

US20030137067A1 Compositions having a combination of immediate release and controlled release characteristics 有权
标题翻译：具有立即释放和控制释放特征组合的组合物
公开(公告)号：US20030137067A1
公开(公告)日：2003-07-24
申请号：US10268928
申请日：2002-10-11
申请人： Elan Pharma International Ltd.
发明人： Eugene R. Cooper , Stephen B. Ruddy
IPC分类号： A61K009/64 , A61K009/14 , B29B009/00
CPC分类号： A61K9/5084 , A61K9/146
摘要： Disclosed are compositions exhibiting a combination of immediate release and controlled release characteristics. The compositions comprise at least one poorly soluble active ingredient having a nanoparticulate particle size, at least one surface stabilizer adsorbed onto the surface of the nanoparticulate active agent particles, and at least one active ingredient having a microparticulate particle size.
摘要翻译：公开了显示即时释放和控释特征组合的组合物。所述组合物包含至少一种具有纳米颗粒粒度的难溶性活性成分，至少一种吸附在纳米颗粒活性剂颗粒表面上的表面稳定剂和至少一种具有微粒尺寸的活性成分。

8. 发明申请

US20160129231A1 Method and Device for Scar Management 审中-公开
标题翻译：疤痕治疗方法与装置
公开(公告)号：US20160129231A1
公开(公告)日：2016-05-12
申请号：US14996389
申请日：2016-01-15
申请人： Elan Pharma International Ltd.
发明人： Jessica Rowen
IPC分类号： A61M35/00 , A61K8/892 , A61K8/02 , A61Q17/04 , A61Q19/00 , A61K8/891 , A61K8/895
CPC分类号： A61H15/02 , A45D34/041 , A61H15/0092 , A61H23/00 , A61H2015/0064 , A61H2201/105 , A61K8/0216 , A61K8/585 , A61K8/891 , A61K8/892 , A61K8/895 , A61K31/695 , A61K31/80 , A61K2800/596 , A61K2800/874 , A61M35/003 , A61M39/22 , A61M2205/19 , A61Q17/04 , A61Q19/00
摘要： A device for scar management includes an applicator head including a recess having a rotating means therein, a reservoir containing a silicone composition fluidly connected to the applicator head, and a metering valve fluidly connected to the reservoir. The composition has viscosity of 3,000 to 8,000 cps, and consists of a mixture of cyclopentasiloxane, dimethiconol, dimethicone, and dimethicone/vinyl dimethicone crosspolymer. A metered dose of the silicone composition is delivered from the reservoir to the applicator head upon the application of external pressure to the metering valve. The invention also relates to a method for scar management using such device by identifying a target skin area having a wound or scar, contacting the outward surface of the applicator head to the target skin area, massaging the rotating means of the applicator head on the target skin area, and applying the silicone composition to the target skin area via the rotating means.
摘要翻译：一种用于瘢痕管理的装置包括：涂抹器头，包括其中具有旋转装置的凹部，包含流体连接到涂抹头的硅氧烷组合物的储存器和流体连接到储存器的计量阀。该组合物具有3,000至8,000cps的粘度，并且由环戊硅氧烷，聚二甲基硅氧烷醇，聚二甲基硅氧烷和聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物的混合物组成。在对计量阀施加外部压力时，计量剂量的硅氧烷组合物从储存器输送到施用器头部。本发明还涉及一种通过识别具有伤口或疤痕的目标皮肤区域使用这种装置的瘢痕管理方法，其将涂抹器头部的外表面接触到目标皮肤区域，按摩目标上的涂抹器头部的旋转装置皮肤区域，并且经由旋转装置将硅氧烷组合物施加到目标皮肤区域。

9. 发明申请

US20040208833A1 Novel fluticasone formulations 审中-公开
标题翻译：新型氟替卡松配方
公开(公告)号：US20040208833A1
公开(公告)日：2004-10-21
申请号：US10768194
申请日：2004-02-02
申请人： Elan Pharma International Ltd.
发明人： Douglas Hovey , Tuula Ryde , H. William Bosch
IPC分类号： A61L009/04 , A61K009/14 , A61K031/573
CPC分类号： A61K9/0073 , A61K9/145 , A61K9/146
摘要： The present invention is directed to fluticasone compositions comprising fluticasone and at least one surface stabilizer. The fluticasone particles of the composition preferably have an effective average particle size of less than about 2000 nm.
摘要翻译：本发明涉及包含氟替卡松和至少一种表面稳定剂的氟替卡松组合物。组合物的氟替卡松颗粒优选具有小于约2000nm的有效平均粒度。

10. 发明申请

US20040115134A1 Novel nifedipine compositions 审中-公开
标题翻译：新硝苯地平组合物
公开(公告)号：US20040115134A1
公开(公告)日：2004-06-17
申请号：US10712259
申请日：2003-11-14
申请人： Elan Pharma International Ltd.
发明人： Elaine Merisko-Liversidge
IPC分类号： A61L009/04
CPC分类号： A61K9/0056 , A61K9/0007 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/2081 , A61K9/2846 , A61K9/4808 , A61K9/5161 , A61K9/5192
摘要： The present invention is directed to nanoparticulate compositions comprising nifedipine. The nifedipine particles of the composition have an effective average particle size of less than about 2 microns.
摘要翻译：本发明涉及包含硝苯地平的纳米颗粒组合物。组合物的硝苯地平颗粒具有小于约2微米的有效平均粒度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式