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1. 发明申请

WO2008020420A3 COMPOSITIONS COMPRISING CALCIUM CITRATE MALATE AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：包含钙柠檬酸钙的组合物及其制备方法
公开(公告)号：WO2008020420A3
公开(公告)日：2008-08-14
申请号：PCT/IB2007053295
申请日：2007-08-17
申请人： PROCTER & GAMBLE , LUHADIYA ASHOK PREMCHAND , DAKE TIMOTHY WILLIAM , HUDEPOHL GLENN RICHARD , COMPTON DONALD BROWN
发明人： LUHADIYA ASHOK PREMCHAND , DAKE TIMOTHY WILLIAM , HUDEPOHL GLENN RICHARD , COMPTON DONALD BROWN
IPC分类号： A61K9/14 , A61K31/19 , A61K33/06
CPC分类号： A61K33/06 , A61K9/145 , A61K9/1688 , A61K31/19 , C07C59/245 , C07C59/265
摘要： Compositions containing calcium citrate malate wherein the calcium citrate malate exhibits one or more of: a pore area of at least about 30m2/g; a dissolution rate of at least about 95% by weight of the calcium citrate malate in less than about 120 seconds.
摘要翻译：含有柠檬酸苹果酸钙的组合物，其中柠檬酸苹果酸钙显示以下一种或多种：孔面积至少约30m 2 / g; 至少约95重量％的柠檬酸柠檬酸苹果酸酯的溶解速率在小于约120秒内。

2. 发明申请

WO2008020420A2 COMPOSITIONS COMPRISING CALCIUM CITRATE MALATE AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：包含柠檬酸钙柠檬酸酯的组合物及其制备方法
公开(公告)号：WO2008020420A2
公开(公告)日：2008-02-21
申请号：PCT/IB2007/053295
申请日：2007-08-17
申请人： THE PROCTER & GAMBLE COMPANY , LUHADIYA, Ashok, Premchand , DAKE, Timothy, William , HUDEPOHL, Glenn, Richard , COMPTON, Donald, Brown
发明人： LUHADIYA, Ashok, Premchand , DAKE, Timothy, William , HUDEPOHL, Glenn, Richard , COMPTON, Donald, Brown
IPC分类号： A61K9/14 , A61K33/06
CPC分类号： A61K33/06 , A61K9/145 , A61K9/1688 , A61K31/19 , C07C59/245 , C07C59/265
摘要： Compositions containing calcium citrate malate wherein the calcium citrate malate exhibits one or more of: a pore area of at least about 30m2/g; a dissolution rate of at least about 95% by weight of the calcium citrate malate in less than about 120 seconds.
摘要翻译：包含柠檬酸苹果酸钙的组合物，其中柠檬酸苹果酸钙表现出以下一种或多种：至少约30m2 / g的孔隙面积; 至少约95％重量的苹果酸柠檬酸钙在小于约120秒内的溶解速率

3. 发明申请

WO2008020421A3 COMPOSITIONS COMPRISING CALCIUM CITRATE MALATE AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：包含钙柠檬酸钙的组合物及其制备方法
公开(公告)号：WO2008020421A3
公开(公告)日：2008-10-16
申请号：PCT/IB2007053296
申请日：2007-08-17
申请人： PROCTER & GAMBLE , LUHADIYA ASHOK PREMCHAND , DAKE TIMOTHY WILLIAM , HUDEPOHL GLENN RICHARD , COMPTON DONALD BROWN
发明人： LUHADIYA ASHOK PREMCHAND , DAKE TIMOTHY WILLIAM , HUDEPOHL GLENN RICHARD , COMPTON DONALD BROWN
IPC分类号： A61K9/14 , A61K31/19 , A61K33/06
CPC分类号： A61K33/06 , A61K9/1688 , A61K31/19 , A61K31/194 , C07C59/245 , C07C59/265
摘要： A process for producing a calcium citrate malate composition by the steps of: combining a calcium source, a citrate source, a malate source and water to form a calcium citrate malate mixture. The mixture is reacted until reaching a peak temperature of from about 45°C to about 70°C, and then cooled at a rate of from about 1°C/minute to about 4°C/minute to reach a final temperature of less than about 40°C. A calcium citrate malate precipitate is formed and then dried to obtain the calcium citrate malate composition.
摘要翻译：一种通过以下步骤生产柠檬酸柠檬酸苹果酸组合物的方法：将钙源，柠檬酸盐源，苹果酸盐和水混合以形成柠檬酸柠檬酸苹果酸盐混合物。使混合物反应直到达到约45℃至约70℃的峰值温度，然后以约1℃/分钟至约4℃/分钟的速率冷却，达到小于约40°C。形成柠檬酸苹果酸钙沉淀物，然后干燥，得到柠檬酸苹果酸钙组合物。

4. 发明申请

WO2008020421A2 COMPOSITIONS COMPRISING CALCIUM CITRATE MALATE AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：包含钙柠檬酸钙的组合物及其制备方法
公开(公告)号：WO2008020421A2
公开(公告)日：2008-02-21
申请号：PCT/IB2007/053296
申请日：2007-08-17
申请人： THE PROCTER & GAMBLE COMPANY , LUHADIYA, Ashok, Premchand , DAKE, Timothy, William , HUDEPOHL, Glenn, Richard , COMPTON, Donald, Brown
发明人： LUHADIYA, Ashok, Premchand , DAKE, Timothy, William , HUDEPOHL, Glenn, Richard , COMPTON, Donald, Brown
IPC分类号： A61K9/14 , A61K33/06
CPC分类号： A61K33/06 , A61K9/1688 , A61K31/19 , A61K31/194 , C07C59/245 , C07C59/265
摘要： A process for producing a calcium citrate malate composition by the steps of: combining a calcium source, a citrate source, a malate source and water to form a calcium citrate malate mixture. The mixture is reacted until reaching a peak temperature of from about 45°C to about 700C, and then cooled at a rate of from about l°C/minute to about 4°C/minute to reach a final temperature of less than about 400C. A calcium citrate malate precipitate is formed and then dried to obtain the calcium citrate malate composition.
摘要翻译：一种通过以下步骤生产柠檬酸柠檬酸苹果酸组合物的方法：将钙源，柠檬酸盐源，苹果酸盐和水混合以形成柠檬酸柠檬酸苹果酸盐混合物。使混合物反应直到达到约45℃至约70℃的峰值温度，然后以约1℃/分钟至约4℃/分钟的速率冷却至达到小于约40℃的最终温度。形成柠檬酸苹果酸钙沉淀物，然后干燥，得到柠檬酸苹果酸钙组合物。

5. 发明专利

AU1734592A MODULAR RESIDENTIAL AMENITIES 未知
公开(公告)号：AU1734592A
公开(公告)日：1992-12-03
申请号：AU1734592
申请日：1992-06-01
申请人： MALCOLM DONALD BROWN
发明人： MALCOLM DONALD BROWN , MURRAY FRANK DAY
IPC分类号： E04B1/348 , E04H1/00

6. 发明专利

JO1599B THERAPEUTIC AGENTS 未知
公开(公告)号：JO1599B
公开(公告)日：1989-12-16
申请号：JO19891599
申请日：1989-10-05
申请人： BOOTS CO PLC , ROY VICTOR DAVIES , MICHAEL DONALD BROWN , NICHOLAS JOHN HOLMAN
发明人： ROY VICTOR DAVIES , MICHAEL DONALD BROWN , NICHOLAS JOHN HOLMAN
摘要： Quinolone sulphonates of formula I In which R1 is lower alkyl, R2 is lower alkyl, and R3 , R3 and R5 which may be the same or different, are hydrogen, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, halo, halogentated lower alkyl, halogenated lower alkoxy, cyano, phenyl or phenyl substituted by 1 or 2 groups independently selected from lower alkyl, lower alkoxy and halo , have antihypertensive activity Processes for preparing compounds of formula I and pharmaceutical composition containing them are described Compounds of formula I are also indicated for use in the treatment of heart failure and ischaemic heart diseases

7. 发明专利

DE1214489B 未知
公开(公告)号：DE1214489B
公开(公告)日：1966-04-14
申请号：DEB0061708
申请日：1961-03-16
申请人： DONALD BROWN BROWNALL LTD
发明人： WAINWRIGHT HERBERT GEOFFREY
IPC分类号： F16L19/10

8. 发明专利

CA457764A PAPER LIFTING DEVICE FOR CUTTING MACHINES AND THE LIKE 未知
公开(公告)号：CA457764A
公开(公告)日：1949-07-05
申请号：CA457764D
申请人： FISHER DONALD BROWN , BRYCE JAMES
发明人： FISHER DONALD BROWN , BRYCE JAMES

9. 发明专利

GB589799A Improved method of forging solid metal articles 未知
公开(公告)号：GB589799A
公开(公告)日：1947-06-30
申请号：GB2545644
申请日：1946-01-21
申请人： DONALD BROWN
IPC分类号： B21J5/02
摘要： 589,799. Forging-dies. BROWN, D. Jan. 21, 1946, No. 25456/44. [Class 83 (iv)] An article is forged from a billet d in a semi-plastic state within a two part die b, c, the base portion c of which has a cylindrical cavity terminating in a conical part provided with an air vent f continuing said cavity, whereby the metal of the blank is forced to flow by pressure applied by a plunger a so as to fill said cavity completely. The plunger is formed with an air vent e.

10. 发明专利

GB586342A Improvements in wall construction 未知
公开(公告)号：GB586342A
公开(公告)日：1947-03-14
申请号：GB2383744
申请日：1944-11-29
申请人： DONALD BROWN
IPC分类号： E04B1/08
摘要： 586,342. Wall stays. BROWN, D. Nov. 29, 1944, No. 23837. [Classes 20 (ii) and 20 (iv)] In a wall or partition formed of interlocked vertical cavity panels of sheet material, continuous flexible stay members are provided tying anchorages in the foundation to members bearing on the tops of the panels. In the form shown, each stay member comprises a twisted double metal strip a the lower end of which passes round a pin k inserted in a loop c of an anchorage d embedded in concrete j. The upper end projects through a cover plate p bearing on the panel elements g, h, and through a clamp r, which connects the cover plate to a supporting T-beam t, and the stay is tensioned by a wedge u. A wedge may also be provided at the lower ends of the strips a and an alternative form of anchorage is described. The stay member may be of wire. Specification 414,677 is referred to

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