专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

2. 发明公开

EP3036008A4 COMPOSITIONS COMPRISING VITAMIN B12 AND INTRINSIC FACTOR AND METHODS OF USE THEREOF 审中-公开
标题翻译：维生素B12和内在因素及其使用方法的组合物
公开(公告)号：EP3036008A4
公开(公告)日：2017-04-05
申请号：EP14837434
申请日：2014-08-22
申请人： DOYLE ROBERT
发明人： DOYLE ROBERT
IPC分类号： A61K31/714 , A61K51/04 , A61P35/04
CPC分类号： A61K51/0497 , A61K31/714 , A61K47/551 , A61K47/64 , A61K51/0472
摘要： A system for detecting cancer cells that targets the cubilin receptor for the vitamin B12 binding protein, intrinsic factor. A B12 conjugate and intrinsic factor is injected into the blood of a patient. The binding of intrinsic factor to cubilin will allow for receptor-mediated endocytosis and cellular internalization by cancerous cells, thereby allowing for detection via imaging or treatment.

3. 发明公开

EP3468576A1 PEPTIDE DRUG IMPROVEMENT USING VITAMIN B12 AND HAPTOCORRIN BINDING SUBSTRATE CONJUGATES 有权转让
公开(公告)号：EP3468576A1
公开(公告)日：2019-04-17
申请号：EP17783228.4
申请日：2017-04-14
申请人： Doyle, Robert
发明人： Doyle, Robert
IPC分类号： A61K38/02 , A61K38/17

5. 发明公开

EP3036008A1 COMPOSITIONS COMPRISING VITAMIN B12 AND INTRINSIC FACTOR AND METHODS OF USE THEREOF 审中-公开
标题翻译： ZUSAMMENSETZUNGEN MIT维生素B12 UND INTRINSISCHEM FAKTOR UND VERFAHREN ZUR VERWENDUNG DAVON
公开(公告)号：EP3036008A1
公开(公告)日：2016-06-29
申请号：EP14837434.1
申请日：2014-08-22
申请人： Doyle, Robert
发明人： DOYLE, Robert
IPC分类号： A61P35/04
CPC分类号： A61K51/0497 , A61K31/714 , A61K47/551 , A61K47/64 , A61K51/0472
摘要： A system for detecting cancer cells that targets the cubilin receptor for the vitamin B12 binding protein, intrinsic factor. A B12 conjugate and intrinsic factor is injected into the blood of a patient. The binding of intrinsic factor to cubilin will allow for receptor-mediated endocytosis and cellular internalization by cancerous cells, thereby allowing for detection via imaging or treatment.
摘要翻译：用于检测针对维生素B12结合蛋白的立方蛋白受体的癌细胞的系统，内在因素。将B12结合物和固有因子注射到患者的血液中。内在因子与cubilin的结合将允许受体介导的胞吞作用和癌细胞的细胞内化，从而允许通过成像或治疗进行检测。

6. 发明专利

CA2921507A1 COMPOSITIONS COMPRISING VITAMIN B12 AND INTRINSIC FACTOR AND METHODS OF USE THEREOF 未知
公开(公告)号：CA2921507A1
公开(公告)日：2015-02-26
申请号：CA2921507
申请日：2014-08-22
申请人： DOYLE ROBERT
发明人： DOYLE ROBERT
IPC分类号： A61K49/00 , A61K31/714 , A61K47/48 , A61K51/04
摘要： A system for detecting cancer cells that targets the cubilin receptor for the vitamin B12 binding protein, intrinsic factor. A B12 conjugate and intrinsic factor is injected into the blood of a patient. The binding of intrinsic factor to cubilin will allow for receptor-mediated endocytosis and cellular internalization by cancerous cells, thereby allowing for detection via imaging or treatment.

7. 发明专利

GB2416064A Tension mounted frame display 未知
公开(公告)号：GB2416064A
公开(公告)日：2006-01-11
申请号：GB0422952
申请日：2004-10-15
申请人： DOYLE ROBERT , DAY STEVEN
发明人： DAY STEVEN
IPC分类号： G09F15/00
摘要： The invention relates to a graphic display system for supporting a display panel/ banner (13) having an elongate stiffening element (3b) along each of two opposed edges. The system comprises first and second support elements (16), each provided with a recess (30) for receiving a stiffening element (3b). The system further comprises third (1) and fourth (2) support elements, each for locating on an underlying surface/ wall and attaching to a respective first or second support element (16). Attachment is by means of an edge (34) of one element locating in a recess (22) in the other element, the attached elements being then pivotable with respect to each other so as to tension the panel/ banner (13) between each pair of attached elements. It is desired that, when the system is in use, the attached elements lie between the panel/ banner and the underlying surface/ wall, so as to be hidden when the panel (13) is viewed from the front. A method of mounting such a system is also described.

9. 发明专利

CA1102918A ELECTRONIC GAME 未知
公开(公告)号：CA1102918A
公开(公告)日：1981-06-09
申请号：CA296475
申请日：1978-02-08
申请人： DOYLE HOLLY THOMIS , DOYLE ROBERT O , THOMIS WENDL
发明人： DOYLE HOLLY T , DOYLE ROBERT O , THOMIS WENDL
IPC分类号： A63F13/00 , A63F9/02
摘要： Game apparatus comprises a control and display console, and a board marked to represent a plurality of ship and submarine positions. The console provides game initiate means providing a game initiate signal, display light means, and player data input switches for input of signals by the player including challenge signals. The apparatus has a randomness source, data storage registers, and submarine data write means responsive to the game initiate signal and to the randomness source for writing initial covert data into the data storage registers. The apparatus further has range clue comparator means responsive to the stored covert data and to the input data signals for outputting clue signals partially representative of the stored covert data for display on the display light means, and challenge comparator means responsive to the stored covert data and to the player input signals including the challenge signals for outputting a challenge outcome indicating signal for display.

10. 发明专利

CA1101454A GAME APPARATUS 未知
公开(公告)号：CA1101454A
公开(公告)日：1981-05-19
申请号：CA321395
申请日：1979-02-13
申请人： DOYLE HOLLY THOMIS , DOYLE ROBERT O , THOMIS WENDL
发明人： DOYLE HOLLY T , DOYLE ROBERT O , THOMIS WENDL
IPC分类号： A63F3/00 , A63F3/02 , A63F9/00 , A63F9/24
摘要： Two playing boards with a matrix array of apertures are positioned so that one board only is displayed to each player. Electric circuitry including contacts are printed on one side of a flexible sheet which is folded so that contacts face each other adjacent each of the apertures. The circuitry is arranged so that the insertion of plugs into corresponding apertures of the two boards moves the contacts carried on the sheet towards each other to close a circuit energizing an audible signal generator.

你已经成功收藏专利！

检索式保存成功!

IPRDB