会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS
    • GPR41及其与胰岛素相关性疾病治疗的调节剂
    • WO2006052566A3
    • 2006-10-12
    • PCT/US2005039551
    • 2005-11-01
    • ARENA PHARM INCLEONARD JAMES NCHU ZHI LIANGBRUCE MARC ABOATMAN P DOUGLAS
    • LEONARD JAMES NCHU ZHI LIANGBRUCE MARC ABOATMAN P DOUGLAS
    • A61K49/00G01N33/50
    • G01N33/66G01N2500/04
    • The present invention relates to a method for identifying a glycemic stabilizing compound by: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is modulated, where a modulation in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound. In addition, the invention relates to a method for identifying a glycemic stabilizing compound, comprising: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is increased, wherein an increase in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound. Further, the invention relates to a method for identifying a glycemic stabilizing compound, comprising: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is decreased, wherein a decrease in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound.
    • 本发明涉及通过以下方式鉴定血糖稳定化合物的方法:a)使候选化合物与GPR41接触,以及b)确定是否调节GPR41功能性,其中GPR41官能度的调节指示候选化合物是血糖稳定剂 复合。 此外,本发明涉及一种鉴定血糖稳定化合物的方法,包括:a)使候选化合物与GPR41接触,和b)确定GPR41的功能是否增加,其中GPR41功能的增加指示候选化合物为 血糖稳定化合物。 此外,本发明涉及用于鉴定血糖稳定化合物的方法,其包括:a)使候选化合物与GPR41接触,和b)确定GPR41的功能性是否降低,其中GPR41官能度的降低指示候选化合物为 血糖稳定化合物。