会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • USE OF ADRENOMEDULLIN AS A THERAPEUTIC AGENT FOR THE TREATMENT OF EXCESSIVE ANGIOGENESIS
    • 将ADRENOMEDULLIN用作治疗过敏原血症的治疗药物
    • WO2009040029A3
    • 2009-12-17
    • PCT/EP2008007738
    • 2008-09-09
    • MONDOBIOTECH LAB AGBEVEC DORIANCAVALLI FABIOCAVALLI VERABACHER GERALD
    • BEVEC DORIANCAVALLI FABIOCAVALLI VERABACHER GERALD
    • A61K38/12A61K38/22A61P3/00A61P9/00A61P11/00A61P25/28A61P31/00A61P31/22A61P35/00A61P37/00
    • A61K38/2242A23L33/18A23L33/40A23V2002/00A61K38/2235A61K2300/00A23V2200/308A23V2200/318A23V2200/322A23V2200/324A23V2200/326A23V2250/55
    • The present invention is directed to the use of the peptide compound Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-lle-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-lle-Ser-Pro-Gln-Gly-Tyr-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-lle-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-lle-Ser-Pro-Gln-Gly-Tyr-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
    • 本发明涉及肽化合物Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly- THR-CYS-THR-VAL-GLN-赖氨酸-LEU-ALA-他-GLN-LLE-酪氨酸 - 谷氨酰胺,苯丙氨酸,苏氨酸,天冬氨酸 - 赖氨酸 - 天冬氨酸 - 赖氨酸 - 天冬氨酸-ASN-VAL-ALA-Pro的-Arg- Ser-Lys-Lle-Ser-Pro-Gln-Gly-Tyr-NH2作为预防和/或治疗癌症,自身免疫疾病,纤维化疾病,炎性疾病,神经变性疾病,传染病,肺部疾病,心脏 和血管疾病和代谢疾病。 此外,本发明涉及优选形式为冻干物或液体缓冲溶液或人造母乳制剂或含有Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly- 亮 - 精 - 为Ser-Phe - 甘氨酸 - 半胱氨酸 - 精氨酸,苯丙氨酸,甘氨酸,苏氨酸,半胱氨酸,苏氨酸,缬氨酸,谷氨酰胺,赖氨酸,亮氨酸,丙氨酸 - 他-GLN-LLE-酪氨酸 - 谷氨酰胺,苯丙氨酸,苏氨酸,Asp-的 Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-1le-Ser-Pro-Gln-Gly-Tyr-NH 2任选与至少一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂 和/或稀释剂。