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1. 发明授权

US11169010B2 Method for the calibration of an implantable sensor 有权
公开(公告)号：US11169010B2
公开(公告)日：2021-11-09
申请号：US12509834
申请日：2009-07-27
申请人： Rocco Crivelli , Danillo Roth , Alec Ginggen
发明人： Rocco Crivelli , Danillo Roth , Alec Ginggen
IPC分类号： A61B5/1495 , G01D11/24 , G01D18/00 , A61B5/0215 , G01L19/08 , A61B5/00 , G01L19/14 , G01D5/353
摘要： An implant includes a processor, RF communication circuitry, optical communication circuitry, a power source and a memory, all of which being hermetically sealed within a housing having a transparent window. Sensor readings are transmitted by RF using the RF communication circuitry to a remote reader after receiving interrogation signals from the reader. During calibration of the sensor, corrective coefficients are calculated by comparing actual sensor pressure readings with known pressure readings. The corrective coefficients are transmitted to the memory of the control circuitry using optical communication wherein modulated light is transmitted through the transparent window of the housing to the photo-detector.

2. 发明授权

US08929996B2 Dual power supply switching circuitry for use in a closed system 有权
公开(公告)号：US08929996B2
公开(公告)日：2015-01-06
申请号：US12381436
申请日：2009-03-11
申请人： Alec Ginggen , Rocco Crivelli
发明人： Alec Ginggen , Rocco Crivelli
IPC分类号： A61N1/08 , H02J7/02 , A61N1/378
CPC分类号： H02J7/025 , A61N1/3787 , H02J1/108 , H02J50/20
摘要： Optimal power switching circuitry for use in a closed system such as a TET system including an internal device separated from an external device by a boundary. The internal and external devices being powered by separate power sources. During telemetric communication from the external device to the internal device an external RF energy source is produced. If the power supplied by the external RF energy source produced during communication from the external device to the internal device exceeds that required for powering of the internal device, then the power switching circuitry cuts off power to the internal power source and instead draws power from the external RF energy source thereby conserving power consumed from the internal power source. The power switching circuitry may be implemented using either passive components (e.g., diodes) or active components (e.g., an analog switch).

3. 发明申请

US20140243933A1 Modulation of the Activity of Mitochondria in Brown Adipose Tissue By Photobiomodulation for the Treatment of Obesity 审中-公开
标题翻译：通过光生物调节处理肥胖的棕色脂肪组织中线粒体的活性调节
公开(公告)号：US20140243933A1
公开(公告)日：2014-08-28
申请号：US13775564
申请日：2013-02-25
申请人： Alec Ginggen
发明人： Alec Ginggen
IPC分类号： A61N5/06
CPC分类号： A61N5/0613 , A61N2005/0659 , A61N2005/0662
摘要： A method for treating obesity by activating non-shivering thermogenesis in mitochondria of targeted brown adipose tissue. A photobiomodulation device including one or more light sources is provided. The mitochondria of the targeted brown adipose tissue is photobiomodulated by exposure to light produced by the light source at a wavelength that modulates photoactivity of an electron transport chain and increases proton transfer across a membrane of the mitochondria of the targeted brown adipose tissue towards an intern space of the mitochondria, without increasing production of adenosine triphosphate.
摘要翻译：通过激活目标棕色脂肪组织的线粒体中不发抖的发热来治疗肥胖症的方法。提供了包括一个或多个光源的光生物调制装置。目标棕色脂肪组织的线粒体通过以调节电子传输链的光活性的波长暴露于由光源产生的光而被光生物调节，并且增加穿过靶向棕色脂肪组织的线粒体的膜向实际空间的质子转移的线粒体，而不增加三磷酸腺苷的产生。

4. 发明申请

US20130313916A1 SYSTEM FOR PROTECTING CIRCUITRY IN HIGH-TEMPERATURE ENVIRONMENTS 有权
标题翻译：保护高温环境电路的系统
公开(公告)号：US20130313916A1
公开(公告)日：2013-11-28
申请号：US13873942
申请日：2013-04-30
申请人： Benito Valencia Avila , Alec Ginggen
发明人： Benito Valencia Avila , Alec Ginggen
IPC分类号： H01H37/72
CPC分类号： H01H37/72 , A61L2/07 , A61M1/127 , A61M5/14276 , A61N1/08 , A61N1/37 , Y10T307/773
摘要： An electrical device for performing a particular function includes a system circuit for performing the function, and a dedicated power supply for providing power to the circuit. Both the system circuit and the power supply are hermetically sealed within a housing. The device within the housing is intended to be sterilized using high temperature, reaching a sterilization temperature. According to the invention, the device includes a thermal switch which is electrically connected between the system circuit and the power supply. With the present invention, the electrical components of a device are automatically protected from thermal damage during sterilization.
摘要翻译：用于执行特定功能的电气设备包括用于执行功能的系统电路和用于向电路提供电力的专用电源。系统电路和电源都被密封在壳体内。外壳内的装置应使用高温灭菌，达到灭菌温度。根据本发明，该装置包括电连接在系统电路和电源之间的热开关。利用本发明，在灭菌期间，装置的电气部件被自动保护免受热损伤。

5. 发明申请

US20090239478A1 Power regulation feedback to optimize robustness of wireless transmissions 有权
标题翻译：功率调节反馈以优化无线传输的鲁棒性
公开(公告)号：US20090239478A1
公开(公告)日：2009-09-24
申请号：US12322076
申请日：2009-01-28
申请人： Alec Ginggen , Rocco Crivelli
发明人： Alec Ginggen , Rocco Crivelli
IPC分类号： H04B7/00
CPC分类号： G06K7/0008 , G06K19/0701 , H04B5/0093 , H04B5/02 , Y02D70/42
摘要： A wireless communication system with power regulation feedback for improving the robustness of wireless communication transmissions between a receiver and an active emitter irrespective of the distance separation therebetween. The receiver receives wireless communications and detects a voltage induced therein. A feedback loop provides wireless transmission of power regulation feedback based on the detected voltage. The active emitter generates a power regulated data signal in which at least one of maximum and minimum bit voltage levels of respective logical high and low bits is adjusted based on the induced voltage received via the feedback loop. The RF power level, modulation index, and/or slew rate of a data signal emitted from the active emitter is regulated by adjusting at least one of maximum and minimum bit voltage levels of respective logical high and low bits based on voltage induced in the receiver during a previous communication from the active emitter.
摘要翻译：一种具有功率调节反馈的无线通信系统，用于改善接收机和有源发射器之间的无线通信传输的鲁棒性，而与它们之间的距离间隔无关。接收机接收无线通信并检测其中引起的电压。反馈回路基于检测到的电压提供功率调节反馈的无线传输。有源发射器产生功率调节数据信号，其中基于经由反馈回路接收的感应电压来调整相应的逻辑高电平和低位的最大和最小位电压电平中的至少一个。从有源发射器发射的数据信号的RF功率电平，调制指数和/或转换速率通过基于在接收机中感应的电压调节相应逻辑高位和低位的最大和最小位电压电平中的至少一个来调节在来自有源发射器的先前通信期间。

6. 发明申请

US20090228077A1 Dual power supply switching circuitry for use in a closed system 有权
标题翻译：用于封闭系统的双电源开关电路
公开(公告)号：US20090228077A1
公开(公告)日：2009-09-10
申请号：US12381436
申请日：2009-03-11
申请人： Alec Ginggen , Rocco Crivelli
发明人： Alec Ginggen , Rocco Crivelli
IPC分类号： A61N1/378
CPC分类号： H02J7/025 , A61N1/3787 , H02J1/108 , H02J50/20
摘要： Optimal power switching circuitry for use in a closed system such as a TET system including an internal device separated from an external device by a boundary. The internal and external devices being powered by separate power sources. During telemetric communication from the external device to the internal device an external RF energy source is produced. If the power supplied by the external RF energy source produced during communication from the external device to the internal device exceeds that required for powering of the internal device, then the power switching circuitry cuts off power to the internal power source and instead draws power from the external RF energy source thereby conserving power consumed from the internal power source. The power switching circuitry may be implemented using either passive components (e.g., diodes) or active components (e.g., an analog switch).
摘要翻译：用于诸如TET系统的封闭系统中的最佳功率切换电路，其包括通过边界与外部设备分离的内部设备。内部和外部设备由独立的电源供电。在从外部设备到内部设备的遥测通信期间，产生外部RF能量源。如果在从外部设备到内部设备的通信期间产生的外部RF能量源所提供的功率超过内部设备供电所需的功率，则功率开关电路切断内部电源的电源，从而节省从内部电源消耗的功率。功率开关电路可以使用无源组件（例如，二极管）或有源组件（例如，模拟开关）来实现。

7. 发明申请

US20090210033A1 Implant revision recognition by exchanging the revision data during transmission 有权
标题翻译：通过在传输过程中交换修订数据进行种植体修订识别
公开(公告)号：US20090210033A1
公开(公告)日：2009-08-20
申请号：US12070618
申请日：2008-02-19
申请人： Rocco Crivelli , Alec Ginggen
发明人： Rocco Crivelli , Alec Ginggen
IPC分类号： A61N1/02
CPC分类号： A61N1/37264 , G06F8/65
摘要： A system and method for establishing communication among a control device and an implantable medical device. The implantable medical device transmits to the control device identification information including a unique identification number associated with the implantable medical device and/or a current version of application software currently being utilized by the implantable medical device. Based on the extracted identification information, the control device correlates thereto a version of the application software from among the multiple versions of application software associated with the control device that is compatible with the recognized version of the application software currently being utilized by the implantable medical device.
摘要翻译：一种用于在控制装置和可植入医疗装置之间建立通信的系统和方法。可植入医疗装置向控制装置发送包括与可植入医疗装置相关联的唯一识别号码和/或可植入医疗装置当前使用的当前版本的应用软件的识别信息。基于所提取的识别信息，控制装置将与控制装置相关联的多个版本的应用软件的版本与可植入医疗装置当前正在使用的应用软件的识别版本兼容。

8. 发明授权

US07285296B2 Process for enriching extracts of natural theanine 失效
标题翻译：丰富天然茶氨酸提取物的方法
公开(公告)号：US07285296B2
公开(公告)日：2007-10-23
申请号：US10686910
申请日：2003-10-16
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： A61M5/00 , A61M25/00 , A61B17/08
CPC分类号： A61M27/006
摘要： An adjustable resistance valve for a cerebrospinal fluid shunt system includes an actuator for allowing the selection of the resistance to flow of the valve, a device for selecting at least one passage traversing across the valve, and a resistance system. The resistance system includes a set of passages each defining a different resistance to flow. The passages are disposed in a circle facing the selecting device such as to guide the flow of the cerebrospinal fluid traversing the passage of the selecting device through the selected passage of the resistance system. The actuator enables one to change the relative position of the selecting device with respect to the resistance system by a rotational movement to select the desired resistance of the valve.
摘要翻译：用于脑脊液分流系统的可调节阻力阀包括用于允许选择阀的流动阻力的致动器，用于选择穿过阀的至少一个通道的装置和阻力系统。电阻系统包括一组通道，每个通道限定不同的阻力。通道设置在面向选择装置的圆圈中，以引导通过选择装置的通道的脑脊液的流动通过电阻系统的选定通道。致动器使得能够通过旋转运动来改变选择装置相对于电阻系统的相对位置，以选择阀的期望电阻。

9. 发明申请

US20060246846A1 Power regulation feedback to optimize robustness of wireless transmissions 有权
公开(公告)号：US20060246846A1
公开(公告)日：2006-11-02
申请号：US11116806
申请日：2005-04-27
申请人： Alec Ginggen , Rocco Crivelli
发明人： Alec Ginggen , Rocco Crivelli
IPC分类号： H04B7/00
CPC分类号： G06K7/0008 , G06K19/0701 , H04B5/0093 , H04B5/02 , Y02D70/42
摘要： A wireless communication system with power regulation feedback for improving the robustness of wireless communication transmissions between a receiver and an active emitter irrespective of the distance separation therebetween. The receiver receives wireless communications and detects a voltage induced therein. A feedback loop provides wireless transmission of power regulation feedback based on the detected voltage. The active emitter generates a power regulated data signal in which at least one of maximum and minimum bit voltage levels of respective logical high and low bits is adjusted based on the induced voltage received via the feedback loop. The RF power level, modulation index, and/or slew rate of a data signal emitted from the active emitter is regulated by adjusting at least one of maximum and minimum bit voltage levels of respective logical high and low bits based on voltage induced in the receiver during a previous communication from the active emitter.

10. 发明申请

US20060107148A1 Automatic self-testing of an internal device in a closed system 有权
标题翻译：在封闭系统中对内部设备进行自动自检
公开(公告)号：US20060107148A1
公开(公告)日：2006-05-18
申请号：US10978247
申请日：2004-10-29
申请人： Alec Ginggen , Rocco Crivelli
发明人： Alec Ginggen , Rocco Crivelli
IPC分类号： G01R31/28
CPC分类号： A61N1/3787 , A61M5/14276 , A61M2205/3523 , A61M2205/3561 , A61M2205/3592 , A61M2205/50 , A61M2205/702 , A61M2205/8212 , A61M2205/8243 , A61N1/36142 , A61N1/37217 , A61N1/37241 , A61N1/37276
摘要： A closed system such as a TET system in which self-testing of all components of the implantable medical device whose malfunction could negatively impact on the proper operation of the closed system is automatically and periodically performed without triggering from an external device. In addition, a closed system including automatic, periodic self-testing of the implantable medical device in which, whenever practical, testing of the components is synchronized with telemetric communication of the external device whereby an external RF field generated by the external device is used to supply necessary power to perform self-testing.
摘要翻译：诸如TET系统的封闭系统，其中可自动且周期性地执行其可能对封闭系统的正常操作产生负面影响的可植入医疗装置的所有部件的自检，而不会从外部设备触发。此外，包括可植入医疗装置的自动定期自检的封闭系统，其中，在任何实际情况下，部件的测试与外部装置的遥测通信同步，由外部装置产生的外部RF场用于提供必要的电力进行自我测试。

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