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1. 发明申请

WO2010064150A3 SYSTEMS AND METHODS FOR DETERMING INTRAOCULAR LENS POWER 审中-公开
标题翻译：用于确定内镜镜片功率的系统和方法
公开(公告)号：WO2010064150A3
公开(公告)日：2010-08-26
申请号：PCT/IB2009008074
申请日：2009-04-06
申请人： AMO REGIONAL HOLDINGS , NORRBY SVERKER , BERGMAN ROLF
发明人： NORRBY SVERKER , BERGMAN ROLF
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61B3/0025 , A61B3/103 , A61B3/107
摘要： A system for providing an intraocular lens includes a processor and a computer readable memory. The computer readable memory is configured to communicate with the processor, the memory having stored therein at least one of: one or more ocular dimensions, and at least one predetermined refractive outcome. The memory further includes a sequence of instructions which, when executed by the processor, cause the processor to select an intraocular lens, select a power of an intraocular lens, or provide an intraocular lens. The sequence of instructions includes determining one or more dimensions of an eye. The instructions also include calculating, based on a mathematical relationship, a distance from an apex of a cornea of the eye to an apex or plane of the intraocular lens after insertion into the eye. The instructions further calculating an optical power of the intraocular lens suitable for providing a predetermined refractive outcome. The mathematical relationship includes an axial length of the eye, an anterior chamber depth of the natural crystalline lens, and a corneal radius of the eye, but is independent of a thickness of the natural crystalline lens.
摘要翻译：用于提供眼内透镜的系统包括处理器和计算机可读存储器。计算机可读存储器被配置为与处理器通信，其中存储有存储器中的至少一个：一个或多个眼睛尺寸和至少一个预定折射结果。所述存储器还包括指令序列，当由所述处理器执行时，使所述处理器选择人工晶状体，选择人工晶状体的能量或提供眼内透镜。指令序列包括确定眼睛的一个或多个维度。说明书还包括基于数学关系计算在插入眼睛之后从眼睛的角膜的顶点到眼内透镜的顶点或平面的距离。所述指令还计算适于提供预定屈光结果的眼内透镜的光焦度。数学关系包括眼睛的轴向长度，天然晶状体的前房深度和眼睛的角膜半径，但是与天然晶状体的厚度无关。

2. 发明申请

WO2010064150A2 SYSTEMS AND METHODS FOR DETERMING INTRAOCULAR LENS POWER 审中-公开
标题翻译：确定眼内镜片能量的系统和方法
公开(公告)号：WO2010064150A2
公开(公告)日：2010-06-10
申请号：PCT/IB2009/008074
申请日：2009-04-06
申请人： AMO REGIONAL HOLDINGS , NORRBY, Sverker , BERGMAN, Rolf
发明人： NORRBY, Sverker , BERGMAN, Rolf
IPC分类号： A61F2/16 , A61B3/10
CPC分类号： A61F2/1613 , A61B3/0025 , A61B3/103 , A61B3/107
摘要： A system for providing an intraocular lens includes a processor and a computer readable memory. The computer readable memory is configured to communicate with the processor, the memory having stored therein at least one of: one or more ocular dimensions, and at least one predetermined refractive outcome. The memory further includes a sequence of instructions which, when executed by the processor, cause the processor to select an intraocular lens, select a power of an intraocular lens, or provide an intraocular lens. The sequence of instructions includes determining one or more dimensions of an eye. The instructions also include calculating, based on a mathematical relationship, a distance from an apex of a cornea of the eye to an apex or plane of the intraocular lens after insertion into the eye. The instructions further calculating an optical power of the intraocular lens suitable for providing a predetermined refractive outcome. The mathematical relationship includes an axial length of the eye, an anterior chamber depth of the natural crystalline lens, and a corneal radius of the eye, but is independent of a thickness of the natural crystalline lens.
摘要翻译：用于提供人工晶状体的系统包括处理器和计算机可读存储器。计算机可读存储器被配置为与处理器通信，存储器中存储有以下中的至少一个：一个或多个眼部尺寸以及至少一个预定的屈光结果。存储器还包括一系列指令，所述指令序列在由处理器执行时使处理器选择眼内透镜，选择眼内透镜的光焦度或提供眼内透镜。指令序列包括确定眼睛的一个或多个维度。该说明书还包括基于数学关系计算在插入眼中之后从眼角膜的顶点到眼内晶状体的顶点或平面的距离。该指令进一步计算适合于提供预定屈光结果的眼内透镜的光焦度。数学关系包括眼睛的轴向长度，自然晶状体的前房深度和眼睛的角膜半径，但与天然晶状体的厚度无关。

3. 发明申请

WO2009140080A3 INTRAOCULAR LENS HAVING EXTENDED DEPTH OF FOCUS 审中-公开
标题翻译：具有延伸焦深的眼内透镜
公开(公告)号：WO2009140080A3
公开(公告)日：2009-12-30
申请号：PCT/US2009042449
申请日：2009-04-30
申请人： AMO REGIONAL HOLDINGS , WEEBER HENDRIK A , PIERS PATRICIA A , REISIN CARINA R
发明人： WEEBER HENDRIK A , PIERS PATRICIA A , REISIN CARINA R
IPC分类号： A61F2/16 , G02C7/04
CPC分类号： G02C7/042 , A61F2/15 , A61F2/1618 , A61F2/1654 , G02B27/0075 , G02C7/028 , G02C2202/20
摘要： An ophthalmic lens for providing enhanced or extended depth of focus includes an optic having an aperture disposed about an optical axis. The optic includes a first surface having a first shape and an opposing second surface having a second shape, the first and second surfaces providing, a base power and, in some embodiments an add power. The optic further includes an extended focus mask disposed upon at least one of the first shape and the second shape that is configured to provide the enhanced or extended depth of focus for one or more foci of the optic, as compared to a similar optic not having the extended focus mask.
摘要翻译：提供增强或延伸焦深的眼科透镜包括具有围绕光轴设置的孔的光学器件。光学器件包括具有第一形状的第一表面和具有第二形状的相对的第二表面，第一和第二表面提供基础功率，并且在一些实施例中提供增加的功率。所述光学器件还包括设置在所述第一形状和所述第二形状中的至少一个上的延伸的聚焦面罩，所述延伸的聚焦面罩被配置为为所述光学器件的一个或多个焦点提供增强的或延伸的焦深，扩展的重点掩码。

4. 发明申请

WO2009140080A2 INTRAOCULAR LENS HAVING EXTENDED DEPTH OF FOCUS 审中-公开
标题翻译：具有延长聚焦深度的内窥镜
公开(公告)号：WO2009140080A2
公开(公告)日：2009-11-19
申请号：PCT/US2009/042449
申请日：2009-04-30
申请人： AMO REGIONAL HOLDINGS , WEEBER, Hendrik, A. , PIERS, Patricia, A. , REISIN, Carina, R.
发明人： WEEBER, Hendrik, A. , PIERS, Patricia, A. , REISIN, Carina, R.
IPC分类号： A61F2/16 , G02C7/04
CPC分类号： G02C7/042 , A61F2/15 , A61F2/1618 , A61F2/1654 , G02B27/0075 , G02C7/028 , G02C2202/20
摘要： An ophthalmic lens for providing enhanced or extended depth of focus includes an optic having an aperture disposed about an optical axis. The optic includes a first surface having a first shape and an opposing second surface having a second shape, the first and second surfaces providing, a base power and, in some embodiments an add power. The optic further includes an extended focus mask disposed upon at least one of the first shape and the second shape that is configured to provide the enhanced or extended depth of focus for one or more foci of the optic, as compared to a similar optic not having the extended focus mask.
摘要翻译：用于提供增强或延伸的焦深的眼科镜片包括具有围绕光轴设置的孔的光学元件。光学元件包括具有第一形状的第一表面和具有第二形状的相对的第二表面，所述第一表面和第二表面提供基本能量，并且在一些实施例中提供附加功率。光学元件还包括设置在第一形状和第二形状中的至少一个上的扩展聚焦掩模，其被配置为为光学器件的一个或多个焦点提供增强或扩展的焦深，与不具有扩展对焦掩码。

5. 发明申请

WO2010100523A1 MULTIZONAL LENS WITH EXTENDED DEPTH OF FOCUS 审中-公开
标题翻译：多重镜头深度聚焦
公开(公告)号：WO2010100523A1
公开(公告)日：2010-09-10
申请号：PCT/IB2009/005590
申请日：2009-03-05
申请人： AMO REGIONAL HOLDINGS , BOGAERT, Theophilus
发明人： BOGAERT, Theophilus
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1602 , A61F2/1618 , A61F2/1645
摘要： An intraocular lens for providing enhanced vision includes an optic having a clear aperture having an outer diameter. The optic has opposing first and second surfaces disposed about an optical axis, the first surface including a cross- sectional profile. The optic further includes central and outer zones that fill the entire clear aperture of the optic. The central zone is disposed about the optical axis having an outer diameter, the profile in the vicinity of the central zone having a constant radius of curvature or a radius of curvature that increases with increasing radius from the optical axis. The outer zone is disposed about the central zone, the profile in the outer zone having a base curvature with a base radius of curvature and a center of curvature, the profile in the outer zone characterized in that, as the distance from the optical axis increases, the distance from the center of curvature of the base curvature also increases.
摘要翻译：用于提供增强视力的眼内透镜包括具有具有外径的透明孔的光学元件。光学元件具有围绕光轴设置的相对的第一和第二表面，第一表面包括横截面轮廓。光学元件还包括填充光学元件的整个透明孔径的中心区域和外部区域。中心区域围绕具有外径的光轴设置，中心区域附近的轮廓具有恒定的曲率半径或曲率半径，随着距离光轴的半径的增加而增加。外部区域围绕中心区域设置，外部区域中的轮廓具有基部曲率，其具有基部曲率半径和曲率中心，外部区域中的轮廓特征在于，随着距离光轴的距离增加距离基础曲率的曲率中心的距离也增加。

6. 发明申请

WO2009027438A2 INTRAOCULAR LENS HAVING EXTENDED DEPTH OF FOCUS 审中-公开
标题翻译：具有延伸焦深的眼内透镜
公开(公告)号：WO2009027438A2
公开(公告)日：2009-03-05
申请号：PCT/EP2008/061235
申请日：2008-08-27
申请人： AMO REGIONAL HOLDINGS , WEEBER, Hendrik A. , PIERS, Patricia Ann
发明人： WEEBER, Hendrik A. , PIERS, Patricia Ann
IPC分类号： A61F2/16
CPC分类号： A61F2/1654 , A61F2002/1699 , G02B27/0075
摘要： An intraocular lens is disclosed, which includes a diffractive element with a relatively low add power. The add power may be less than about 2 Diopters, may be less than about 1 Diopter, or may be in the ranges of 0.5 to 2.5 Diopters, or 1.0 lo 2.0 Diopters, or 1.5 to 2.0 Diopters, or 1.0 to 1.5 Diopters. The low-add-power diffractive element increases the depth of the focus of the intraocular lens, for example, compared to a similarly shaped intraocular lens without the diffractive element. In one embodiment, the depth of focus is defined in terms of a threshold MTF value at a particular spaiml frequency. The threshold may be an absolute threshold, such as 0.10, 0.15, 0.17, 0.20, 0.25 or 0.30, or may be a relative threshold, such as a particular percentage of the peak value. The spatial frequency may be 25 line pairs per mm. 50 line pairs per mm. 100 line pairs per mm, or any suitable value.
摘要翻译：公开了一种人工晶状体，其包括具有相对较低的加入力的衍射元件。附加屈光力可以小于约2屈光度，可以小于约1屈光度，或者可以在0.5屈光度到2.5屈光度或1.0屈光度2.0或1.5屈光度到2.0屈光度或1.0到1.5屈光度的范围内。例如，与没有衍射元件的类似形状的人工晶状体相比，低附加功率衍射元件增加了人工晶状体的焦点深度。在一个实施例中，焦点深度根据特定空间频率处的阈值MTF值来定义。阈值可以是绝对阈值，诸如0.10,0.15,0.17,0.20,0.25或0.30，或者可以是相对阈值，诸如峰值的特定百分比。空间频率可以是每毫米25线对。每毫米50线对。每毫米100线对，或任何合适的值。

7. 发明申请

WO2009101202A1 SYSTEM, OPHTHALMIC LENS, AND METHOD FOR EXTENDING DEPTH OF FOCUS 审中-公开
标题翻译：系统，眼科镜片和扩大聚焦深度的方法
公开(公告)号：WO2009101202A1
公开(公告)日：2009-08-20
申请号：PCT/EP2009/051783
申请日：2009-02-16
申请人： AMO REGIONAL HOLDINGS , WEEBER, Hendrik, A. , PIERS, Patricia, Ann , ARTAL, Pablo , MANZANERA, Silvestre
发明人： WEEBER, Hendrik, A. , PIERS, Patricia, Ann , ARTAL, Pablo , MANZANERA, Silvestre
IPC分类号： G02C7/02 , A61F2/16
CPC分类号： A61F2/1637 , A61F2/14 , A61F2/1613 , A61F2/1618 , A61F2/1654 , A61F2/1659 , A61F2240/002 , G02C7/02 , G02C2202/20 , G02C2202/22
摘要： System, ophthalmic lens, and method for extending depth of focus includes an optic having a clear aperture disposed about a central axis. The optic includes a first surface and an opposing second surface. The first and second surfaces are configured to introduce an asymmetric aberration to the eye while maintaining the in-focus visual acuity.
摘要翻译：用于延伸焦深的系统，眼用透镜和方法包括具有围绕中心轴线设置的透明孔的光学元件。光学元件包括第一表面和相对的第二表面。第一和第二表面被配置为在保持对焦视力的同时向眼睛引入不对称像差。

8. 发明申请

WO2007030623A2 BI-MODAL HYALURONATE SOLUTION 审中-公开
标题翻译：双模式透明质酸溶液
公开(公告)号：WO2007030623A2
公开(公告)日：2007-03-15
申请号：PCT/US2006/034864
申请日：2006-09-07
申请人： AMO REGIONAL HOLDINGS , BERGMAN, Rolf , LUNDQVIST, Maria , MANNBERG, Stig , LUNDGREN, Bjorn , SHIMIZU, Robert
发明人： BERGMAN, Rolf , LUNDQVIST, Maria , MANNBERG, Stig , LUNDGREN, Bjorn , SHIMIZU, Robert
IPC分类号： A61K47/36 , A61L31/04 , C08L5/08
CPC分类号： A61K9/0048 , A61K31/717 , A61K31/728 , A61K31/737 , A61K31/785 , A61K47/36
摘要： Formulations and methods for protecting cell layers and tissues exposed to trauma are disclosed. Different molecular mass fractions of the same polymer can be used to better control the physical and chemical properties of the formulation. In this manner the benefits of both fractions, and not just the benefits of the average of the fractions, can be seen in the formulation.
摘要翻译：公开了用于保护暴露于创伤的细胞层和组织的制剂和方法。可以使用相同聚合物的不同分子量级分来更好地控制制剂的物理和化学性质。以这种方式，可以在配方中看到两种馏分的益处，而不仅仅是馏分平均的益处。

9. 发明申请

WO2009027438A3 INTRAOCULAR LENS HAVING EXTENDED DEPTH OF FOCUS 审中-公开
标题翻译：具有延长聚焦深度的内窥镜
公开(公告)号：WO2009027438A3
公开(公告)日：2009-04-16
申请号：PCT/EP2008061235
申请日：2008-08-27
申请人： AMO REGIONAL HOLDINGS , WEEBER HENDRIK A , PIERS PATRICIA ANN
发明人： WEEBER HENDRIK A , PIERS PATRICIA ANN
IPC分类号： A61F2/16
CPC分类号： A61F2/1654 , A61F2002/1699 , G02B27/0075
摘要： An intraocular lens is disclosed, which includes a diffractive element with a relatively low add power. The add power may be less than about 2 Diopters, may be less than about 1 Diopter, or may be in the ranges of 0.5 to 2.5 Diopters, or 1.0 lo 2.0 Diopters, or 1.5 to 2.0 Diopters, or 1.0 to 1.5 Diopters. The low-add-power diffractive element increases the depth of the focus of the intraocular lens, for example, compared to a similarly shaped intraocular lens without the diffractive element. In one embodiment, the depth of focus is defined in terms of a threshold MTF value at a particular spaiml frequency. The threshold may be an absolute threshold, such as 0.10, 0.15, 0.17, 0.20, 0.25 or 0.30, or may be a relative threshold, such as a particular percentage of the peak value. The spatial frequency may be 25 line pairs per mm. 50 line pairs per mm. 100 line pairs per mm, or any suitable value.
摘要翻译：公开了一种眼内透镜，其包括具有相对低的附加功率的衍射元件。附加功率可以小于约2屈光度，可以小于约1屈光度，或者可以在0.5至2.5屈光度范围内，或1.0低2.0屈光度或1.5至2.0屈光度或1.0至1.5屈光度的范围内。例如，与没有衍射元件的类似形状的眼内透镜相比，低附加功率衍射元件增加了眼内透镜的焦点的深度。在一个实施例中，焦点的深度是根据特定的spaiml频率的阈值MTF值定义的。阈值可以是绝对阈值，例如0.10,0.15,0.17,0.20,0.25或0.30，或者可以是相对阈值，例如峰值的特定百分比。空间频率可以是每mm 25个线对。每行50行对。 100线对/ mm或任何合适的值。

10. 发明申请

WO2007030623A3 BI-MODAL HYALURONATE SOLUTION 审中-公开
标题翻译： BI-MODAL HYALURONATE溶液
公开(公告)号：WO2007030623A3
公开(公告)日：2007-07-26
申请号：PCT/US2006034864
申请日：2006-09-07
申请人： AMO REGIONAL HOLDINGS , BERGMAN ROLF , LUNDQVIST MARIA , MANNBERG STIG , LUNDGREN BJORN , SHIMIZU ROBERT
发明人： BERGMAN ROLF , LUNDQVIST MARIA , MANNBERG STIG , LUNDGREN BJORN , SHIMIZU ROBERT
IPC分类号： A61K47/36 , A61L31/04 , C08L5/08
CPC分类号： A61K9/0048 , A61K31/717 , A61K31/728 , A61K31/737 , A61K31/785 , A61K47/36
摘要： Formulations and methods for protecting cell layers and tissues exposed to trauma are disclosed. Different molecular mass fractions of the same polymer can be used to better control the physical and chemical properties of the formulation. In this manner the benefits of both fractions, and not just the benefits of the average of the fractions, can be seen in the formulation.
摘要翻译：公开了用于保护暴露于创伤的细胞层和组织的制剂和方法。可以使用相同聚合物的不同分子量级分来更好地控制制剂的物理和化学性质。以这种方式，在制剂中可以看到两种级分的益处，而不仅仅是平均级分的益处。

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