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1. 发明申请

WO2012091824A1 METHOD OF TREATING SKIN WITH microRNA MODULATORS 审中-公开
标题翻译：用microRNA调节剂处理皮肤的方法
公开(公告)号：WO2012091824A1
公开(公告)日：2012-07-05
申请号：PCT/US2011/061656
申请日：2011-11-21
申请人： AVON PRODUCTS, INC. , KHUSIAL, Permanan Raaj , SANTHANAM, Uma , LYGA, John W.
发明人： KHUSIAL, Permanan Raaj , SANTHANAM, Uma , LYGA, John W.
IPC分类号： A61K31/33 , A61K31/17 , A61K31/12
CPC分类号： C07C311/17 , A61K8/466 , A61K8/4926 , A61K2800/782 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C12Q1/6883 , C12Q2600/136 , C12Q2600/148 , C12Q2600/158 , C12Q2600/178
摘要： Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microRNA expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific microRNAs and the methods of using active agents identified by the screening protocol in the treatment of skin.
摘要翻译：提供了用于预防，改善或减少皮肤老化迹象的方法，其使用抑制或下调真皮成纤维细胞中的microRNA表达的活性剂，导致皮肤中胶原，弹性蛋白和/或原纤维蛋白的产生增加。还提供了用于筛选针对特定微小RNA的活性的方法以及使用筛选方案鉴定的活性剂治疗皮肤的方法。

2. 发明申请

WO2011156136A1 USE OF ECLIPTA PROSTRATA AND OTHER PPAR-GAMMA INHIBITORS IN COSMETICS AND COMPOSITIONS THEREOF 审中-公开
标题翻译： ECLIPTA PROSTRATA和其他PPAR-GAMMA抑制剂在化妆品及其组合物中的应用
公开(公告)号：WO2011156136A1
公开(公告)日：2011-12-15
申请号：PCT/US2011/037886
申请日：2011-05-25
申请人： AVON PRODUCTS, INC. , HWANG, Cheng, S. , SANTHANAM, Uma , RANDHAWA, Manpreet
发明人： HWANG, Cheng, S. , SANTHANAM, Uma , RANDHAWA, Manpreet
IPC分类号： A61K8/97 , A61K36/28
CPC分类号： A61Q19/06 , A61K8/97 , A61K36/28
摘要： The present invention describes compositions and methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Eclipta prostrata extracts or other anti-lipid agents.
摘要翻译：本发明描述了用于改善皮肤外观的组合物和方法，特别是治疗，改善，预防，延迟和/或改善皮肤脂肪过量积聚和/或产生的一种或多种迹象，例如脂肪团和相关条件通过局部施用包含Eclipta prostrata提取物或其它抗脂质剂的组合物。

3. 发明申请

WO2011082044A1 TOPICAL LIGHTENING COMPOSITION AND USES THEREOF 审中-公开
标题翻译：主题亮点组合物及其用途
公开(公告)号：WO2011082044A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/061688
申请日：2010-12-22
申请人： AVON PRODUCTS, INC. , LYGA, John W. , SANTHANAM, Uma , WELSH, William J.
发明人： LYGA, John W. , SANTHANAM, Uma , WELSH, William J.
IPC分类号： A61K31/74
CPC分类号： A61K31/74 , A61K8/46 , A61Q19/02
摘要： The disclosure relates to novel topical lightening compositions a tyrosinase inhibitor and a vehicle. There is provided a topical lightening composition comprising a 2-substituted-thio-4-substitued-4-oxobutanoic acid, ester or amide tyrosinase inhibitor, and a vehicle. The tyrosinase inhibitors of this disclosure can be used as such or as a pharmaceutically acceptable salt including conventional non-toxic salts which include a metal salt or an alkaline earth metal salt, an ammonium salt, or an organic base salt. The tyrosinase inhibitors of this disclosure can be incorporated into any cosmetically-, dermatologically-, or cosmeticatically- acceptable vehicle or carrier normally used for topical application. The compositions and methods of the disclosure are effective to lighten skin, hair, lips, and/or nails.
摘要翻译：本公开涉及新型局部减轻组合物酪氨酸酶抑制剂和载体。提供了包含2-取代 - 硫代-4-取代-4-氧代丁酸，酯或酰胺酪氨酸酶抑制剂和载体的局部减轻组合物。本公开的酪氨酸酶抑制剂可以原样使用或作为药学上可接受的盐使用，包括常规无毒盐，其包括金属盐或碱土金属盐，铵盐或有机碱盐。本公开的酪氨酸酶抑制剂可以并入通常用于局部应用的任何美容，皮肤病学或化妆品可接受的载体或载体中。本公开的组合物和方法有效地减轻皮肤，头发，嘴唇和/或指甲。

4. 发明申请

WO2011082032A1 COSMETIC POWDER BEAD COMPOSITIONS 审中-公开
标题翻译：化妆粉珠组合物
公开(公告)号：WO2011082032A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/061545
申请日：2010-12-21
申请人： AVON PRODUCTS, INC. , KHAN, Raheel , SLADE, Donald , DAWKINS, Marsha C.
发明人： KHAN, Raheel , SLADE, Donald , DAWKINS, Marsha C.
IPC分类号： A61Q5/12
CPC分类号： A61K8/26 , A61K8/0287 , A61K8/73 , A61K8/731 , A61K8/733 , A61K8/737 , A61K8/8147 , A61K8/8182 , A61K8/86 , A61K8/90 , A61Q1/08 , A61Q1/10 , A61Q1/12
摘要： The present disclosure relates to beads comprising at least one structuring agent and least one powder, a novel process that forms beads of a desired size having the versatility of a loose powder but the convenience of a compact form, and compositions comprising the beads.
摘要翻译：本公开涉及包含至少一种结构化剂和至少一种粉末的珠粒，形成具有松散粉末的通用性但是紧凑形式的方便性的所需尺寸的珠粒和包含珠粒的组合物的新方法。

5. 发明申请

WO2011056547A1 METHODS AND COMPOSITIONS FOR PREVENTING OR REDUCING FRIZZY APPEARANCE OF HAIR 审中-公开
标题翻译：防止或减少头发外露的方法和组合物
公开(公告)号：WO2011056547A1
公开(公告)日：2011-05-12
申请号：PCT/US2010/054051
申请日：2010-10-26
申请人： AVON PRODUCTS, INC. , GARRISON, Mark, S. , ROBINSON, Freda, E. , SANDSTROM, Giovana, A. , BUCKRIDGE, Kenneth, A. , YANG, Sen , LUO, Xiaochun
发明人： GARRISON, Mark, S. , ROBINSON, Freda, E. , SANDSTROM, Giovana, A. , BUCKRIDGE, Kenneth, A. , YANG, Sen , LUO, Xiaochun
IPC分类号： A61K8/06
CPC分类号： A61K8/0241 , A61K8/26 , A61K8/585 , A61K8/8152 , A61K8/891 , A61K8/895 , A61K8/897 , A61K8/898 , A61K2800/413 , A61K2800/623 , A61Q5/06
摘要： Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.
摘要翻译：公开了用于防止或减少包括毛发在内的角蛋白纤维的卷曲外观的组合物和方法，并且通过在头发上形成对来自空气的水蒸气具有抗性的毛发上的涂层来减少特别是在潮湿条件下的飞散的毛发的量或周围环境。组合物包含在化妆品可接受的载体中包含疏水表面改性的氧化物和一种或多种疏水性成膜剂的疏水性颗粒材料的组合。

6. 发明申请

WO2010078181A1 COSMETIC USE OF 1-AROYL-N-(2-OXO-3-PIPERIDINYL)-2-PIPERAZINE CARBOXAMIDES AND RELATED COMPOUNDS 审中-公开
标题翻译： 1-氨基-N-（2-氧代-3-哌啶子基）-2-哌啶羧酸酯及相关化合物的化学应用
公开(公告)号：WO2010078181A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/069372
申请日：2009-12-23
申请人： AVON PRODUCTS, INC. , PTCHELINTSEV, Dmitri, S. , HU, Hong , MENON, Gopinathan, K. , SCHMALENBERG, Kristine , LYGA, John, W.
发明人： PTCHELINTSEV, Dmitri, S. , HU, Hong , MENON, Gopinathan, K. , SCHMALENBERG, Kristine , LYGA, John, W.
IPC分类号： A61K31/497
CPC分类号： A61K31/496 , A61K8/494 , A61Q19/00 , A61Q19/08
摘要： Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
摘要翻译：公开了包含1-芳酰基-N-（2-氧代-3-哌啶基）-2-哌嗪甲酰胺的化妆品组合物和使用这些组合物给皮肤赋予抗衰老益处的方法。据信1-芳酰基-N-（2-氧代-3-哌啶基）-2-哌嗪甲酰胺具有针对涉及皮肤老化的一种或多种生物化学途径的调节活性。

7. 发明申请

WO2008097799A1 MULTI-UNIT COSMETIC APPLICATOR 审中-公开
标题翻译：多单位化妆品应用者
公开(公告)号：WO2008097799A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/052595
申请日：2008-01-31
申请人： AVON PRODUCTS, INC. , PECHKO, Andrew H. , KUREK, John S.
发明人： PECHKO, Andrew H. , KUREK, John S.
IPC分类号： A45D40/02
CPC分类号： A45D40/02 , A45D34/00 , A45D34/04 , A45D34/06 , A45D40/10 , A45D40/24
摘要： A multi-unit cosmetic applicator comprising: a housing body, a first cosmetic unit housed in the housing body, a second cosmetic unit housed in the housing body, an opening in the housing, wherein each cosmetic unit has a means for being independently movable relative to each other from a stored position to an advanced position and back to its stored position.
摘要翻译：一种多单元化妆品涂抹器，包括：壳体，容纳在壳体中的第一化妆品单元，容纳在壳体中的第二化妆品单元，壳体中的开口，其中每个化妆品单元具有用于独立移动的相对从存储位置到提前位置并且返回到其存储位置。

8. 发明申请

WO2008079560A2 COSMETIC COMPOSITION CONTAINING NOVEL FRACTAL PARTICLE BASED GELS HAVING IMPROVED OPTICAL PROPERTIES 审中-公开
标题翻译：包含具有改进的光学性能的新型分形颗粒基凝胶的化妆品组合物
公开(公告)号：WO2008079560A2
公开(公告)日：2008-07-03
申请号：PCT/US2007/085179
申请日：2007-11-20
申请人： AVON PRODUCTS, INC. , BROWN, Steven E. , CURTIS, Ernest S.
发明人： BROWN, Steven E. , CURTIS, Ernest S.
IPC分类号： A61Q19/08 , A61Q1/00 , A61K8/06
CPC分类号： A61K8/042 , A61K8/0275 , A61K8/19 , A61K8/25 , A61K8/26 , A61K8/28 , A61K8/29 , A61K8/345 , A61K8/375 , A61K8/891 , A61K8/894 , A61K2800/26 , A61K2800/262 , A61K2800/412 , A61K2800/413 , A61Q1/02 , B82Y5/00
摘要： A method of instantly reducing the appearance of wrinkles and skin imperfections while smoothing the skin, which comprises applying a cosmetic composition in the form of an oil-in-water emulsion comprising a fractal particle based gel and refractive index matching polymers with respect to at least one of the fractal particles. The composition of the invention provides both optical blurring and skin smoothing effect on the skin.
摘要翻译：一种在平滑皮肤的同时立即减少皱纹和皮肤瑕疵的出现的方法，该方法包括施用水包油乳液形式的化妆品组合物，所述化妆品组合物包含基于分形颗粒的凝胶和折射折射率匹配聚合物相对于至少一个分形颗粒。本发明的组合物对皮肤提供光学模糊和皮肤平滑效果。

9. 发明申请

WO2007070168A2 COSMETIC COMPOSITIONS WITH ENCAPSULATED PIGMENTS AND A METHOD FOR USING 审中-公开
标题翻译：化妆品组合物与封装颜料和使用方法
公开(公告)号：WO2007070168A2
公开(公告)日：2007-06-21
申请号：PCT/US2006/041553
申请日：2006-10-23
申请人： AVON PRODUCTS, INC. , SIMARD, Claude, C. , SHAH, Arvind, N.
发明人： SIMARD, Claude, C. , SHAH, Arvind, N.
IPC分类号： A61K9/00 , A61K8/02
CPC分类号： A61Q1/02 , A61K8/0241 , A61K8/19 , A61K8/25 , A61K8/29 , A61K2800/412 , A61K2800/436 , A61K2800/621 , A61K2800/651 , A61Q3/02
摘要： There is a pigmented cosmetic composition. The composition has a cosmetically acceptable vehicle, a cosmetic active, and a plurality of encapsulated pigment particles. The particles have an encapsulant and an entrapped pigment within the encapsulant. The encapsulant has silicon dioxide and exhibits a refractive index of about 1.4 to about 1.6.
摘要翻译：有着色的化妆品组合物。该组合物具有美容上可接受的载体，美容活性物质和多个包囊颜料颗粒。颗粒在密封剂中具有密封剂和捕获的颜料。密封剂具有二氧化硅并且具有约1.4至约1.6的折射率。

10. 发明申请

WO2006026168A1 IMPROVED TOPICAL SKIN CARE COMPOSITIONS 审中-公开
标题翻译：改进的局部皮肤护理组合物
公开(公告)号：WO2006026168A1
公开(公告)日：2006-03-09
申请号：PCT/US2005/029212
申请日：2005-08-16
申请人： AVON PRODUCTS, INC. , GONZALEZ, Anthony, D. , HUBBARD, Barbara, J. , ANDERSON, Glen , KALAFSKY, Robert, E.
发明人： GONZALEZ, Anthony, D. , HUBBARD, Barbara, J. , ANDERSON, Glen , KALAFSKY, Robert, E.
IPC分类号： A61K8/893
CPC分类号： A61K8/891 , A61K8/25 , A61Q17/00 , A61Q17/02 , A61Q17/04 , A61Q19/00
摘要： A novel combination of silicon resin, amorphous silica and low oil absorbing spherical powder is described which when added to topical skin care compositions containing high concentrations of active agents, improves their aesthetic feel and ease of application.
摘要翻译：描述了硅树脂，无定形二氧化硅和低吸油性球形粉末的新型组合，当加入到含有高浓度活性剂的局部护肤组合物中时，其可提高其美学感觉和易于使用。

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