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1. 发明申请

WO2003086532A1 IMPLANTABLE MEDICAL LEAD WITH MOVABLE FIXATION 审中-公开
标题翻译：具有可移动固定的可植入医用引线
公开(公告)号：WO2003086532A1
公开(公告)日：2003-10-23
申请号：PCT/US2003/011201
申请日：2003-04-10
申请人： MEDTRONIC, INC.
发明人： TRONNES, Carole, A. , SWOYER, John, M. , GERBER, Martin, T.
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/375
摘要： An implantable intramuscular lead system, such as for use as a gastric lead, and method of use in which electrodes along the lead are imbedded in tissue. First and second anchors are mounted onan elongate lead. At least the second anchor is movable along the length of the lead relative to the first anchor to capture the tissue between the anchors so that the lead is retained in position. The systefacilitates implantation of the lead in tissue, and may be particularly suited for minimally invasive implantation, such as laparoscopically.
摘要翻译：植入式肌内引线系统，例如用作胃引物，以及其中沿着引线的电极嵌入组织中的使用方法。第一和第二锚固件安装在细长的引线上。至少第二锚定件可以相对于第一锚定件沿着导线的长度移动以捕获锚固件之间的组织，使得引线保持就位。有助于植入组织中的铅，并且可以特别适用于微创植入，例如腹腔镜下。

2. 发明申请

WO2003002180A2 CATHETER SYSTEM HAVING DISPOSABLE BALLOON 审中-公开
标题翻译：具有一次性气球的导管系统
公开(公告)号：WO2003002180A2
公开(公告)日：2003-01-09
申请号：PCT/US2002/019922
申请日：2002-06-24
申请人： MEDTRONIC, INC.
发明人： GRECO, Francesco , JORGENSEN, Kenneth , NIELSEN, Marianne , PEDERSEN, Anders , AUNDAL, Knud
IPC分类号： A61M25/00
CPC分类号： A61M25/1029 , A61B5/205 , A61B5/6853 , A61B17/12109 , A61B17/12136 , A61M25/10 , A61M25/1027 , A61M2025/1054
摘要： A disposable balloon catheter and corresponding catheter system are disclosed. In one embodiment, the catheter system comprises several components, such as: (a) an elongated catheter comprising a first outer diameter, a first proximal end and a first distal end; (b) an elongated balloon carrier having a second proximal end, a second distal end and a second outer diameter, the second proximal end of the carrier and the first distal end of the catheter being configured to permit the first distal end of the catheter to matingly engage the second proximal end of the carrier, the second outer diameter of the balloon carrier being similar to the first outer diameter of the catheter; and (c) a disposable balloon formed from an expandable and resilient biocompatible material, the balloon having a lumen disposed between a third proximal end and a third distal end thereof, the lumen having at least a third inside diameter. The second proximal end of the carrier and the first distal end of the catheter are preferably configured to permit the first distal end of the catheter to matingly engage the second proximal end of the carrier. In a preferred embodiment, the second outer diameter of the balloon carrier is similar to the first outer diameter of the catheter such that the second diameter of the carrier and the third diameter of the balloon permit the balloon first to be slideably mounted onto the balloon carrier and second to be slideably moved from the carrier onto the catheter when the second proximal end of the carrier is matingly or otherwise suitably engaged with the first distal end of the catheter.
摘要翻译：公开了一次性气囊导管和相应的导管系统。在一个实施例中，导管系统包括几个部件，例如：（a）细长导管，其包括第一外径，第一近端和第一远端; （b）具有第二近端，第二远端和第二外径的细长囊体载体，载体的第二近端和导管的第一远端被配置为允许导管的第一远端到配合地接合所述载体的所述第二近端，所述囊载体的所述第二外径与所述导管的所述第一外径相似; 和（c）由可膨胀且有弹性的生物相容性材料形成的一次性气囊，所述气囊具有设置在其第三近端和第三远端之间的内腔，所述内腔具有至少第三内径。载体的第二近端和导管的第一远端优选地构造成允许导管的第一远端匹配地接合载体的第二近端。在优选实施例中，气囊载体的第二外径类似于导管的第一外径，使得载体的第二直径和气囊的第三直径允许气囊首先可滑动地安装到气囊载体上并且其次当载体的第二近端与导管的第一远端匹配或以其他方式适当接合时，从载体可滑动地移动到导管上。

3. 发明申请

WO2002087693A3 PRESSURE-MODULATED RATE-RESPONSIVE CARDIAC PACING 审中-公开
公开(公告)号：WO2002087693A3
公开(公告)日：2002-11-07
申请号：PCT/US2002/012962
申请日：2002-04-26
申请人： MEDTRONIC,INC.
发明人： STRUBLE, Chester, L.
IPC分类号： A61N1/365
摘要： Techniques for pacing the heart of a patient as a function of an intra-cardiac pressure make use of a pressure monitor that receives a pressure signal from a pressure sensor in the patient's right ventricle. The pressure monitor estimates the patient's pulmonary artery diastolic pressure. A rate-responsive pacemaker paces the patient's heart as a function of the estimated pulmonary artery diastolic pressure.

4. 发明申请

WO2002058752A3 MEDICAL DEVICE AND METHODS OF USE 审中-公开
公开(公告)号：WO2002058752A3
公开(公告)日：2002-08-01
申请号：PCT/US2001/044435
申请日：2001-11-27
申请人： MEDTRONIC, INC.
发明人： HENDRIKS, Marc
IPC分类号： A61L31/00
摘要： The present invention provides a medical device that includes a carrier and a polynucleotide, where the carrier has a surface that includes a polymer with which the polynucleotide is associated. In another aspect, the present invention provides a medical device that includes a carrier and a cell that expresses an antimicrobial peptide, where the carrier has a surface that includes a polymer with which the cell is associated. The present invention further provides methods of making and using medical devices that include a carrier and a polynucleotide or a cell.0.

5. 发明申请

WO2002045792A3 METHOD AND SYSTEM FOR PREVENTING THE RECURRENCE OF ATRIAL FIBRILLATION BY AN IMPLANTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2002045792A3
公开(公告)日：2002-06-13
申请号：PCT/US2001/046643
申请日：2001-12-04
申请人： MEDTRONIC, INC.
发明人： EVERS, Xander , VAN DER VEEN, Johannes, S.
IPC分类号： A61N1/368
摘要： A method for preventing the recurrence of an atrial fibrillation of a heart is provided. An atrial fibrillation is detected. A set of pacing pulses to increase a rate of the heart to an intervention rate is transmitted to the heart upon the completion of the atrial fibrillation. Finally, the intervention rate is maintained for a predetermined period of time.

6. 发明申请

WO2002087695A1 DIAGNOSTIC FEATURES IN BIATRIAL AND BIVENTRICULAR PACING SYSTEMS 审中-公开
标题翻译：双歧和双歧叉系统的诊断特征
公开(公告)号：WO2002087695A1
公开(公告)日：2002-11-07
申请号：PCT/US2002/009895
申请日：2002-03-29
申请人： MEDTRONIC, INC.
发明人： STRUBLE, Chester, L.
IPC分类号： A61N1/368
CPC分类号： A61N1/368
摘要： A biatrial and/or biventricular pacing system is used in a diagnostic context. By placing a pacing/sensing lead in three or four chambers of the heart, various conduction sequences can be determined and the originating chamber of various arrhythmias can be identified. This information is stored temporarily in the pacemaker until it is extracted for analysis.
摘要翻译：在诊断环境中使用生物学和/或双心室起搏系统。通过将起搏/感测引线放置在心脏的三个或四个腔室中，可以确定各种传导序列，并且可以识别各种心律不齐的发生室。该信息临时存储在起搏器中，直到它被提取用于分析。

7. 发明申请

WO2002087693A2 PRESSURE-MODULATED RATE-RESPONSIVE CARDIAC PACING 审中-公开
标题翻译：压力调节率响应心脏瓣膜
公开(公告)号：WO2002087693A2
公开(公告)日：2002-11-07
申请号：PCT/US2002/012962
申请日：2002-04-26
申请人： MEDTRONIC,INC.
发明人： STRUBLE, Chester, L.
IPC分类号： A61N1/365
CPC分类号： A61N1/36564 , A61N1/3627
摘要： Techniques for pacing the heart of a patient as a function of an intra-cardiac pressure make use of a pressure monitor that receives a pressure signal from a pressure sensor in the patient's right ventricle. The pressure monitor estimates the patient's pulmonary artery diastolic pressure. A rate-responsive pacemaker paces the patient's heart as a function of the estimated pulmonary artery diastolic pressure.
摘要翻译：作为心脏内压力的函数使患者的心脏起搏的技术使用从患者右心室中的压力传感器接收压力信号的压力监视器。压力监测器估计患者的肺动脉舒张压。速率响应性心脏起搏器作为估计的肺动脉舒张压的函数，对患者的心脏起搏。

8. 发明申请

WO2002087438A3 CLOSED LOOP NEUROMODULATION FOR SUPPERSSION OF EPILEPTIC ACTIVITY 审中-公开
公开(公告)号：WO2002087438A3
公开(公告)日：2002-11-07
申请号：PCT/US2002/010995
申请日：2002-04-05
申请人： MEDTRONIC, INC.
发明人： WADMAN, Wytse , GIELEN, Frans, L., H.
IPC分类号： A61B5/0484
摘要： A system and method for predicting the likelihood of occurrence of an impending neurological episode. Electrical stimuli are delivered to a structure of the brain. Response field potentials evoked by the stimuli are sensed. Analysis of these field potentials allows for predictions as to the occurrence of an impending, but not yet occurring, neurological disorder. In one example, a measurement of change in response pulses is used to determine a level of interconnectivity in the structures of the brain. The level of functional interconnectivity is used in predicting the occurrence of the neurological event. An example of such a neurological event includes an epileptic seizure.

9. 发明申请

WO2002068047A2 SYSTEM AND METHOD FOR REMOTE PROGRAMMING OF AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于远程编程的可植入医疗器械的系统和方法
公开(公告)号：WO2002068047A2
公开(公告)日：2002-09-06
申请号：PCT/US2002/001583
申请日：2002-01-17
申请人： MEDTRONIC, INC.
发明人： HALLER, Markus , FEREK-PETRIC, Bozidar , DONDERS, Adrianus, P.
IPC分类号： A61N1/372
CPC分类号： A61N1/37264 , A61B5/0031 , A61N1/08 , A61N1/37211 , A61N1/37282 , G06F8/65 , G06F19/00 , G06F19/3418 , G16H40/40
摘要： A method and corresponding system for updating or installing new software loaded into the memory of an implantable medical device (IMD) implanted within a body of a patient is described. The updated or new software may be installed in the memory of the IMD without the patient having to travel to a clinic or hospital, and may be effected by employing modern telecommunication and Internet techniques in conjunction with a remote computer system.
摘要翻译：描述了一种用于更新或安装加载到植入在患者身体内的可植入医疗装置（IMD）的存储器中的新软件的方法和对应系统。更新的或新的软件可以安装在IMD的存储器中，而不需要病人去诊所或医院，并且可以通过结合远程计算机系统采用现代电信和因特网技术来实现。

10. 发明申请

WO2001052934A1 SYSTEM AND METHOD OF COMMUNICATING BETWEEN AN IMPLANTABLE MEDICAL DEVICE AND A REMOTE COMPUTER SYSTEM OR HEALTH CARE PROVIDER 审中-公开
标题翻译：可移植医疗设备与远程计算机系统或健康护理提供者之间的通信系统和方法
公开(公告)号：WO2001052934A1
公开(公告)日：2001-07-26
申请号：PCT/US2001/001639
申请日：2001-01-18
申请人： MEDTRONIC, INC.
发明人： HALLER, Markus , DONDERS, Andrianus, P. , FEREK-PETRIC, Bozidar
IPC分类号： A61N1/36
CPC分类号： A61N1/37264 , A61B5/0031 , A61N1/37211 , A61N1/37282 , G06F19/00 , G06F19/3418
摘要： A medical information communication system and corresponding methods are described. The system permits monitoring the performance of an implantable medical device (IMD) (14) implanted within a body of a patient, monitoring the health of the patient, or remotely delivering a therapy to the patient through the IMD. The IMD is capable of bi-directional communication with a communication module (100/110), a mobile telephone and/or personal data assistant (PDA) located outside the patient's body. The system may comprise the IMD, the communication module and/or mobile telephone and/or a PDA, a remote computer system (131), and a communication system (120) capable of bi-directional communication, where the communication module, the mobile telephone and/or the PDA are capable of receiving information from the IMD or relaying information thereto.
摘要翻译：描述医疗信息通信系统及相应的方法。该系统允许监测植入在患者身体内的可植入医疗装置（IMD）（14）的性能，监测患者的健康状况，或通过IMD远程传递给患者的治疗。 IMD能够与位于患者体外的通信模块（100/110），移动电话和/或个人数据助理（PDA）进行双向通信。该系统可以包括IMD，通信模块和/或移动电话和/或PDA，远程计算机系统（131）和能够进行双向通信的通信系统（120），其中通信模块，移动电话和/或PDA能够从IMD接收信息或向其传送信息。

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