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1. 发明申请

WO2007094653A1 ADENOVIRUS PARTICLES HAVING A CHIMERIC ADENOVIRUS SPIKE PROTEIN, USE THEREOF AND METHODS FOR PRODUCING SUCH PARTICLES. 审中-公开
标题翻译：具有本发明的ADENOVIRUS SPIKE蛋白的腺病毒颗粒，其用途和用于生产这种颗粒的方法。
公开(公告)号：WO2007094653A1
公开(公告)日：2007-08-23
申请号：PCT/NL2006/000072
申请日：2006-02-13
申请人： VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG , VAN BEUSECHEM, Victor, Willem , SCHAGEN, Frederik, Hubertus, Emanuel
发明人： VAN BEUSECHEM, Victor, Willem , SCHAGEN, Frederik, Hubertus, Emanuel
IPC分类号： C12N15/861 , C12N5/10
CPC分类号： C07K14/005 , C07K2319/73 , C07K2319/74 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10345 , C12N2720/12022 , C12N2720/12034 , C12N2810/6063
摘要： The present invention is concerned with means and methods for producing adenovirus particles comprising a chimeric adenovirus spike protein that essentially lacks a functional knob domain. One aspect of the invention is concerned with a method for producing adenovirus particles comprising providing cells that are permissive for adenovirus replication with an adenovirus vector, with nucleic acid encoding said chimeric adenovirus spike protein and with nucleic acid encoding at least one adenovirus E3 region protein or a functional part, derivative and/or analogue thereof, said method further comprising culturing said permissive cells to allow for at least one replication cycle of said adenovirus virus and harvesting said adenovirus particle.
摘要翻译：本发明涉及用于产生包含基本上缺乏功能性旋钮结构域的嵌合腺病毒尖峰蛋白的腺病毒颗粒的方法和方法。本发明的一个方面涉及用于产生腺病毒颗粒的方法，包括提供允许腺病毒复制的细胞与腺病毒载体，编码所述嵌合腺病毒穗状蛋白的核酸和编码至少一种腺病毒E3区蛋白的核酸或其功能部分，衍生物和/或类似物，所述方法还包括培养所述允许细胞以允许所述腺病毒病毒的至少一个复制循环并收获所述腺病毒颗粒。

2. 发明申请

WO2006088352A1 VENTILATING APPARATUS WITH PRESSURE-DEPENDENTLY REGULATING VALVE 审中-公开
标题翻译：带压力调节阀的通风装置
公开(公告)号：WO2006088352A1
公开(公告)日：2006-08-24
申请号：PCT/NL2005/000142
申请日：2005-02-18
申请人： ALUSTA NATUURLIJKE VENTILATIETECHNIEK B.V. , MEESTER, Andreas, Wilhelmus, Jozef , ZWAAN, Adrianus, Jacobus
发明人： MEESTER, Andreas, Wilhelmus, Jozef , ZWAAN, Adrianus, Jacobus
IPC分类号： F24F11/047
CPC分类号： F24F11/75
摘要： A ventilating apparatus provided with a substantially block-shaped housing (1) with a ventilating channel (2) extending in it, while at least one valve body is present for pressure-dependently regulating the free passage of the ventilating channel, for which purpose the valve body is designed as a body arranged to be substantially freely rotatable about a pivot (9) and provided with at least two closing legs (12, 13) and an initiating leg (14), while one of the closing legs in the initial position extends in and opposite to the flow direction of the ventilating air through the ventilating channel, with respect to which leg a further closing leg and an initiating leg are arranged so as to diverge in a V-shape. The pivot for the valve body, viewed in the flow direction of the air in the ventilating channel, is preferably placed in the outflow mouth area or just behind it.
摘要翻译：一种通风设备，其具有基本上为块状的壳体（1），其具有在其中延伸的通风通道（2），同时存在至少一个阀体，用于压力依赖地调节通风通道的自由通道，为此，阀体被设计为主体，其布置成可围绕枢轴（9）基本上可自由旋转并设置有至少两个闭合腿（12,13）和起始腿（14），而其中一个闭合腿处于初始位置通过通风通道延伸并相对于通风空气的流动方向，相对于哪个腿，另外的关闭腿和起始腿被布置成以V形的方式发散。在通气通道中的空气的流动方向上看到的阀体的枢轴优选地放置在流出口区域中或者恰好在其后面。

3. 发明申请

WO2006080841A1 MEANS AND METHODS FOR IMPROVING THE DEVELOPMENT AND MATURATION OF EGGS AND/OR SPERM IN FISH USING HORMONES PRODUCED BY TRANSPLANTED CELLS 审中-公开
标题翻译：使用由移植细胞产生的细胞来改善鱼和/或鱼的发育和成熟的手段和方法
公开(公告)号：WO2006080841A1
公开(公告)日：2006-08-03
申请号：PCT/NL2006/000043
申请日：2006-01-26
申请人： UNIVERSITEIT LEIDEN , SPAINK, Herman Pieter , VAN DEN THILLART, Guido Everard Elisabeth Johannes Maria , SCHNABEL PERAZA, Denhi
发明人： SPAINK, Herman Pieter , VAN DEN THILLART, Guido Everard Elisabeth Johannes Maria , SCHNABEL PERAZA, Denhi
IPC分类号： C12N15/85 , A01K61/00
CPC分类号： A61K38/24 , A01K67/0271 , A01K2207/12 , A01K2227/40 , A01K2267/02 , C07K14/59 , C07K2319/43
摘要： The invention is concerned with means and methods for improving the development and/or maturation of eggs and/or sperm in fish using hormone administration comprising providing said fish with cells producing said hormone. Preferred hormones are fertility hormones such as luteinizing hormone (LH), follicle stimulating hormone (FSH)or chorionic gonadotropin (CG) or a functional part, derivative and/or analogue thereof.
摘要翻译：本发明涉及用于使用激素给药来改善鱼和/或精子的发育和/或成熟的方法和方法，包括向所述鱼提供产生所述激素的细胞。优选的激素是诸如黄体生成激素（LH），促卵泡激素（FSH）或绒毛膜促性腺激素（CG）或其功能性部分，衍生物和/或类似物的生殖激素。

4. 发明申请

WO2006041277A1 APPARATUS AND METHOD FOR FORMING END PRODUCTS FROM PLASTIC 审中-公开
标题翻译：从塑料制成最终产品的装置和方法
公开(公告)号：WO2006041277A1
公开(公告)日：2006-04-20
申请号：PCT/NL2004/000726
申请日：2004-10-15
申请人： HARDEMAN, Wim, Albertus, Cornelis
发明人： HARDEMAN, Wim, Albertus, Cornelis
IPC分类号： B29B17/00 , B29C45/53 , B29C45/72 , B29C39/38
CPC分类号： B29B17/0026 , Y02W30/62
摘要： An apparatus for forming end products from plastic comprising a plunger (4) for pressing plastic through a shell, wherein the shell extends substantially between a feed chamber (3) and a mold (18), the shell comprising, successively, in feed-through direction, a feed chamber, a heating chamber (10) and a discharge, the discharge being connected with the mold, while in the shell in the heating chamber, preferably, a reduced portion (11) has been provided for increasing pressure on the plastic.
摘要翻译：一种用于从塑料形成最终产品的装置，包括用于将塑料挤压通过壳体的柱塞（4），其中壳体基本上在进料室（3）和模具（18）之间延伸，壳体依次连续地进给方向，进料室，加热室（10）和排出口，排放物与模具连接，而在加热室的壳体中，优选地，已经设置了减小部分（11）以增加塑料上的压力。

5. 发明申请

WO2006028371A1 METHOD AND DEVICE FOR INVERSE MULTIPLEXING OF MULTICAST TRANSMISSION 审中-公开
标题翻译：用于多播传输的反向多路复用的方法和装置
公开(公告)号：WO2006028371A1
公开(公告)日：2006-03-16
申请号：PCT/NL2005/000651
申请日：2005-09-09
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO , LAARHUIS, Jan, Herman
发明人： LAARHUIS, Jan, Herman
IPC分类号： H04L12/18 , H04L12/28 , H04M11/06
CPC分类号： H04L12/18 , H04L1/1685 , H04L12/185 , H04L12/2861
摘要： A stream of multicast messages is forwarded through a network to a plurality of subscriber devices (18). The stream is inverse multiplexed and transmitted distributed over a plurality of communication channels (14). A plurality of inverse demultiplexers (16) is provided, to reassemble a plurality of copies of the stream from the multiplexed streams from the communication channels at different locations. Preferably, the final communication channels to a plurality of subscribers (e.g. telephone lines to different homes) are used as communication channels for said inverse multiplexing and the inversely multiplexed data is communicated locally (17) between the subscribers to enable reassembly of copies of the stream.
摘要翻译：通过网络将多播消息流转发到多个订户设备（18）。该流被反向多路复用，并分布在多个通信信道（14）上。提供了多个反向解复用器（16），以在来自不同位置的来自通信信道的复用流中重组流的多个副本。优选地，到多个用户（例如到不同家庭的电话线）的最终通信信道被用作用于所述反向多路复用的通信信道，并且反向多路复用数据在用户之间在本地（17）被传送以使得能够重新组装流

6. 发明申请

WO2006016814A3 SYSTEM FOR MAKING A BEVERAGE, AS WELL AS A RESTRICTION-ELEMENT AND A PAD EVIDENTLY INTENDED FOR SUCH A SYSTEM, AS WELL AS A METHOD FOR MAKING A BEVERAGE AND USE OF THE SYSTEM FOR MAKING A BEVERAGE 审中-公开
公开(公告)号：WO2006016814A3
公开(公告)日：2006-02-16
申请号：PCT/NL2005/000589
申请日：2005-08-12
申请人： DE N.V. Sara Lee , KOELING, Hendrik, Cornelis , BROUWER, Gustaaf, Frans
发明人： KOELING, Hendrik, Cornelis , BROUWER, Gustaaf, Frans
IPC分类号： A47J31/06
摘要： A system for making a beverage, the system comprising a pad (7) and a holder (6) in which the pad (7) is placed in use, the pad being provided with a chamber in which a product (24) required for making the beverage is situated, the system defining, at least partly, a fluid path, while the fluid path extends, in use, at least through the product (24) in the pad (7), while in use a fluid is introduced into the fluid path under super-atmospheric pressure, wherein the system is designed for assuming two conditions, i.e. a froth condition in which a beverage with a froth layer is produced, and a froth-free condition in which a beverage substantially without froth layer is produced. Also is described a restriction element (15a, 16, 18, 19, 20) and a pad (7) and the use of such a system as a method for making beverage.

7. 发明申请

WO2006009436A1 USE OF SPHINGOLIPIDS FOR PREVENTION AND TREATMENT OF ATHEROSCLEROSIS 审中-公开
标题翻译：用于预防和治疗甲状腺功能亢进症的用途
公开(公告)号：WO2006009436A1
公开(公告)日：2006-01-26
申请号：PCT/NL2005/000518
申请日：2005-07-18
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO , NIEUWENHUIZEN, Willem Ferdinand , EMEIS, Josephus, Jan , HAVEKES, Aloysius, Maria
发明人： NIEUWENHUIZEN, Willem Ferdinand , EMEIS, Josephus, Jan , HAVEKES, Aloysius, Maria
IPC分类号： A61K31/133
CPC分类号： A61K31/133 , A61K31/688
摘要： The present invention is in the field of prevention and treatment of atherosclerosis and atherosclerosis-related clinical conditions. In particular, the present invention relates to the use of sphingolipids, more preferably phytosphingosine, sphingosine, sphinganine, ceramide, cerebroside lyso-sphingomyelin and/or sphingomyelin for prevention and treatment of inflammatory processes associated with atherosclerosis, psoriasis,colitis or auto-immune diseases in a subject.
摘要翻译：本发明涉及动脉粥样硬化和动脉粥样硬化相关临床病症的预防和治疗领域。特别地，本发明涉及鞘脂，更优选植物鞘氨醇，鞘氨醇，鞘氨醇，神经酰胺，脑脊液溶血磷脂和/或鞘磷脂用于预防和治疗与动脉粥样硬化，牛皮癣，结肠炎或自身免疫疾病相关的炎性过程的用途在一个主题

8. 发明申请

WO2005092753A1 APPARATUS AND METHOD FOR STACKING OBJECTS 审中-公开
标题翻译：用于堆叠对象的装置和方法
公开(公告)号：WO2005092753A1
公开(公告)日：2005-10-06
申请号：PCT/NL2005/000221
申请日：2005-03-24
申请人： TRM PATENTEN B.V. , LALESSE, Robert , VAN SCHIJNDEL, Marcel
发明人： LALESSE, Robert , VAN SCHIJNDEL, Marcel
IPC分类号： B65G57/26
CPC分类号： B65G57/26 , B65G2201/025
摘要： An apparatus for stacking objects, provided with positioning means (3) which are designed for ranging the objects (2) in specific, substantially horizontal stacking positions (P), while the apparatus (1) is provided with conveying means (4, 14) desgined for conveying the objects (2) from the positioning means to a stacking area for stacking the objects (2) onto each other, the apparatus (1) being provided with stacking pattern maintaining means (5) which are at least designed for substantially maintaining said stacking patterns (P) during the stacking of each object (2) in the stacking area. The invention further provides a method for stacking objects.
摘要翻译：一种用于堆叠物体的装置，设置有定位装置（3），该定位装置设计成在特定的基本水平的堆叠位置（P）中将物体（2）测距，同时设备（1）设置有输送装置（4,14）设计用于将物体（2）从定位装置输送到用于将物体（2）彼此堆叠的堆叠区域，所述设备（1）设置有堆叠图案保持装置（5），其至少设计成基本上保持在每个物体（2）在堆叠区域堆叠期间的所述堆叠图案（P）。本发明还提供了一种用于堆叠物体的方法。

9. 发明申请

WO2005085608A1 EXHAUST SYSTEM FOR MOTORCYCLES 审中-公开
标题翻译：汽车排气系统
公开(公告)号：WO2005085608A1
公开(公告)日：2005-09-15
申请号：PCT/NL2005/000171
申请日：2005-03-08
申请人： L-SIM B.V. , VAN DER MARK, Nicolaas, Jan, Franciscus
发明人： VAN DER MARK, Nicolaas, Jan, Franciscus
IPC分类号： F01N7/16
CPC分类号： F01N13/16 , F01N13/14
摘要： The invention relates to an exhaust system for motorcycles, which is provided over at least a part of the outer surface with a covering, more in particular a decorative covering, comprising a basic exhaust system of metal, a substantially gas-tight, thermally insulating layer over the exhaust system and an outer layer comprising a glass fibre fabric embedded in a cured synthetic resin.
摘要翻译：本发明涉及一种用于摩托车的排气系统，其在外表面的至少一部分上设置有覆盖物，特别是装饰性覆盖物，其包括金属的基本排气系统，基本上气密的隔热层并且包括嵌入固化的合成树脂中的玻璃纤维织物的外层。

10. 发明申请

WO2005084415A1 SEED PELLETS AND SOILS FOR GROWING PLANTS 审中-公开
标题翻译：种植花粉和土壤用于生长植物
公开(公告)号：WO2005084415A1
公开(公告)日：2005-09-15
申请号：PCT/EP2005/002265
申请日：2005-03-01
申请人： EUROCHEM N.V. , HAVDRA, Jiri , VAN HULLE, Bart, André, Maria
发明人： HAVDRA, Jiri , VAN HULLE, Bart, André, Maria
IPC分类号： A01C1/06
CPC分类号： C05D3/02 , A01C1/06 , A01C21/00 , A01G22/00 , C05D9/00 , C05D9/02 , C05G3/0058
摘要： The invention relates to the field of seed germination and growing of plants. A composition comprising a clay, an inert material, optionally a fibrous material, and a fourth component is provided, characterized in that said fourth component comprises a cation selected from the group consisting of Al, Zr and Ti and an anion selected from the group consisting of oxyhydroxide, oxychloride, nitrate, sulfate, chloride, hydroxide and alkoxide, and wherein the concentration of said fourth component ranges from 0.1 to 70 per cent by weight (w%), preferably 0.5-25 w%, more preferably 1-10 w%, of the total weight of the clay, the inert material, and optionally the fibrous material, together.
摘要翻译：本发明涉及种子发芽和植物生长的领域。提供了包含粘土，惰性材料，任选的纤维材料和第四组分的组合物，其特征在于所述第四组分包含选自Al，Zr和Ti的阳离子和选自以下的阴离子：羟基氧化物，氯氧化物，硝酸盐，硫酸盐，氯化物，氢氧化物和醇盐，其中所述第四组分的浓度为0.1-70重量％（w％），优选0.5-25重量％，更优选1-10w 一起，粘土，惰性材料和任选的纤维材料的总重量的百分比。

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