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1. 发明公开

EP0863799A2 NOVEL PHOTOCATALYST, PREPARATION THEREFOR AND METHOD FOR PRODUCING HYDROGEN USING THE SAME 失效
标题翻译：新型光催化，生产和制氢的方法一样，
公开(公告)号：EP0863799A2
公开(公告)日：1998-09-16
申请号：EP96932065.0
申请日：1996-09-17
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： PARK, Dae, Chul 6-503 Gongdong Apartment , LIM, Sang, Yun
IPC分类号： B01J27 , B01J35 , C01B3
CPC分类号： B01J35/004 , B01J27/043 , B01J35/002 , C01B3/042 , Y02E60/364
摘要： The present invention relates to a novel photocatalyst for producing hydrogen, harmless to the environment and by which a large quantity of hydrogen is efficiently produced at low temperatures without using any organic promoter, represented by the following formula: Cs(a)H(c)/S(b), wherein 'a' represents a percentage by weight of impregnated Cs on the basis of the weight of a carrier, being limited up to 6.0; 'H' is a promoter selected from Ni, Co and Fe; 'c' represents a percentage by weight of the promoter on the basis of the total weight of Cs and the promoter, being limited up to 50.0; 'S' is the carrier consisting of a zinc sulfide mixture comprising an inorganic compound and zinc sulfide with the molar ratio of zinc: sulfur ranging from 1:0.1 to 1:2.8; and 'b' represents a percentage by weight of the inorganic compound on the basis of the total amount of the ZnS mixture, being limited up to 50. Also, the present invention relates to a method for preparing the photocatalyst and to a method for producing hydrogen using the photocatalyst.

2. 发明公开

EP0845986A1 PHARMACEUTICAL COMPOSITION FOR TREATING CARDIOVASCULAR DISEASES CONTAINING 3-(2,2,2-TRIMETHYLHYDRAZINIUM) PROPIONATE AND GAMMA-BUTYROBETAINE 失效
标题翻译：与心脏GEFÄSSERCRANE注释的处理3-（2,2,2-三甲基肼）丙酸酯和γ-丁基甜菜碱药物组合物
公开(公告)号：EP0845986A1
公开(公告)日：1998-06-10
申请号：EP96927931.0
申请日：1996-08-20
申请人： Kalvinsh, Ivars , Veveris, Maris
发明人： Kalvinsh, Ivars , Veveris, Maris
IPC分类号： A61K9 , A61K31 , A61P9
CPC分类号： A61K31/205 , A61K31/15 , A61K2300/00
摘要： The invention relates to η-butyrobetaine and 3-(2,2,2-trimethylhydrazinium) propionate (Mildronate)-containing pharmaceutical compositions for oral, parenteral, subcutaneous or rectal administration for the treatment of heart-blood vessel diseases of various genesis and localization, blood circulation disturbances, stenocardia, myocardium infarction, arrhythmia, hypertension, myocarditis and low cardiac potency. This composition in the experiments on anaesthetized cats at a dose of 5 mg/kg of η-butyrobetaine + 5 mg/kg of Mildronate, i.v. increases a total blood flow by 18 %, blood pressure and heart rhythm being practically unchanged. The composition arrests adrenaline-induced blood vessel spasms in isolated rabbit ear, in a concentration of 2.0 νM of η-butyrobetaine + 2.0 νM of Mildronate, it decreases reperfusion pressure by 33 %. NO-synthase blocking essentially decreases the composition effect on adrenaline-induced blood vessel spasms. At a dose of 60 mg/kg of η-butyrobetaine + 40 mg/kg of Mildronate, the composition by 70 % declines mouse lethality from CaCl2-induced arrhythmia, and at a dose of 30 mg/kg of η-butyrobetaine + 30 mg/kg of Mildronate, p.o. by 60 % decreases rat lethality from CaCl2-induced arrhythmia. In the prophylactic and therapeutic regimens at a dose of 50 mg/kg of $(g)g-butyrobetaine + 50 mg/kg of Mildronate, the composition in the experiments on rats effectively prevents myocardium from occlusion-reperfusion-induced failures and ventricular fibrillations. In the comparative experiments the claimed composition demonstrates a more potent effect as compared with the known preparation Mildronate and η-butyrobetaine effects if they are applied separately. The composition is notable for a low toxicity and wide interval of therapeutic action safety.

3. 发明公开

EP0839827A1 Novel polyhydro derivatives of tylosine and process for their preparation 失效
标题翻译： Neue Polyhydroderivate von Tylosin und deren Herstellung
公开(公告)号：EP0839827A1
公开(公告)日：1998-05-06
申请号：EP97118553.3
申请日：1997-10-24
申请人： PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo
发明人： Narandja, Amalija , Lopotar, Nevenka
IPC分类号： C07H17/08
CPC分类号： C07H17/08
摘要： The invention relates to 13-hydroxy-tylosine derivatives, novel semisynthetic antibiotics from the class of macrolides, and to a process for the preparation thereof. According to the present invention by a reductive opening of the oxirane ring of tylosine 13-hydroxy compounds are obtained, which are then subjected to a hydrogenation of the double bond and then 13-hydroxy dihydro or tetrahydro compounds are subjected to an oximation reaction or 13-hydroxy oximes are subjected to the hydrogenation of the double bond.
摘要翻译：本发明涉及13-羟基 - 泰乐菌素衍生物，大环内酯类的新型半合成抗生素及其制备方法。根据本发明，得到泰乐菌素13-羟基化合物的环氧乙烷环的还原开口，然后将其进行双键氢化，然后使13-羟基二氢或四氢化合物进行肟化反应或13 - 羟基肟进行双键的氢化。

4. 发明公开

EP0820998A3 Novel coumarin quinolone carboxylic acids and processes for the preparation thereof 失效
标题翻译： Coumarinchinoloncarbonsäure和它们的制备方法
公开(公告)号：EP0820998A3
公开(公告)日：1998-04-29
申请号：EP97112743.6
申请日：1997-07-24
申请人： PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko drustvo
发明人： Trkovnik, Mladen , Ivezic, Zrinka , Kelneric, Zeljko , Polak, Ljerka
IPC分类号： C07D491/052 , C07D491/147 , A61K31/435
CPC分类号： C07D411/04 , C07D491/14
摘要： The present invention relates to novel coumarin quinolone carboxylic acids wherein the pyridone system is fused in 3,4-, 6,7- and 7,8-positions of the coumarin system, of the general formula I
wherein
R 1 R 2 = -NHCH=C(CO 2 R 6 )CO-, R 3 = NO 2 or NH 2 , R 4 = R 5 = H, R 6 = H or C 2 H 5 ; R 1 R 2 = -NHCH=C(CO 2 R 6 )CO-, R 3 = R 4 = H, R 5 = F, R 6 = H or C 2 H 5 ; R 1 R 2 = -CO(CO 2 R 6 )C=CHNH-, R 3 = R 4 = R 5 = H, R 6 = H or C 2 H 5 ; R 1 R 2 = R 3 R 4 = -NHCH=C(CO 2 R 6 )CO-, R 5 = H, R 6 = H or C 2 H 5 ; R 1 = H or OH, R 2 = R 5 = H, R 3 R 4 = -NHCH=C(CO 2 R 6 )CO-, R 6 = H or C 2 H 5 ; R 1 = OH, R 2 = R 3 = H, R 4 R 5 =-CO(CO 2 R 6 )C=CHNH-, R 6 = H or C 2 H 5 ; R 1 = R 5 = H, R 2 = CH 3 or CF 3 , R 3 R 4 = -CO(CO 2 R 6 )C=CHNH-, R 6 = H or C 2 H 5 , as well as pharmaceutically acceptable salts thereof. The object of the invention are also processes for the preparation of novel coumarin quinolone carboxylic acids and the biological action thereof.

5. 发明公开

EP0820998A2 Novel coumarin quinolone carboxylic acids and processes for the preparation thereof 失效
标题翻译：香茅chin ure ure ure ure。。。。。。。。。。。
公开(公告)号：EP0820998A2
公开(公告)日：1998-01-28
申请号：EP97112743.6
申请日：1997-07-24
申请人： PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko drustvo
发明人： Trkovnik, Mladen , Ivezic, Zrinka , Kelneric, Zeljko , Polak, Ljerka
IPC分类号： C07D491/052 , C07D491/147 , A61K31/435
CPC分类号： C07D411/04 , C07D491/14
摘要： The present invention relates to novel coumarin quinolone carboxylic acids wherein the pyridone system is fused in 3,4-, 6,7- and 7,8-positions of the coumarin system, of the general formula I
wherein

R 1 R 2 = -NHCH=C(CO 2 R 6 )CO-, R 3 = NO 2 or NH 2 , R 4 = R 5 = H, R 6 = H or C 2 H 5 ;
R 1 R 2 = -NHCH=C(CO 2 R 6 )CO-, R 3 = R 4 = H, R 5 = F, R 6 = H or C 2 H 5 ;
R 1 R 2 = -CO(CO 2 R 6 )C=CHNH-, R 3 = R 4 = R 5 = H, R 6 = H or C 2 H 5 ;
R 1 R 2 = R 3 R 4 = -NHCH=C(CO 2 R 6 )CO-, R 5 = H, R 6 = H or C 2 H 5 ;
R 1 = H or OH, R 2 = R 5 = H, R 3 R 4 = -NHCH=C(CO 2 R 6 )CO-, R 6 = H or C 2 H 5 ;
R 1 = OH, R 2 = R 3 = H, R 4 R 5 =-CO(CO 2 R 6 )C=CHNH-, R 6 = H or C 2 H 5 ;
R 1 = R 5 = H, R 2 = CH 3 or CF 3 , R 3 R 4 = -CO(CO 2 R 6 )C=CHNH-, R 6 = H or C 2 H 5 ,
as well as pharmaceutically acceptable salts thereof.
The object of the invention are also processes for the preparation of novel coumarin quinolone carboxylic acids and the biological action thereof.
摘要翻译：本发明涉及新颖的香豆素喹诺酮羧酸，其中吡啶酮体系在香豆素体系的3,4,6,7和7,8位融合，通式I 其中R 1， R 2 = -NHCH = C（CO 2 R 6）CO-，R 3 = NO 2或NH 2，R 4 = R 5 = H，R 6 = H或C 2 H 5; R 1 R 2 = -NHCH = C（CO 2 R 6）CO-，R 3 = R 4 = H，R 5 = F，R 6 = H或C 2 H 5; R 1 R 2 = -CO（CO 2 R 6）C = CHNH-，R 3 = R 4 = R 5 = H，R 6 = H或C 2 H 5; R 1 R 2 = R 3 R 4 = -NHCH = C（CO 2 R 6）CO-，R 5 = H，R 6 = H或C 2 H 5; R 1 = H或OH，R 2 = R 5 = H，R 3 R 4 = -NHCH = C（CO 2 R 6）CO-，R 6 = H或 C2H5; R 1 = OH，R 2 = R 3 = H，R 4 R 5 = -CO（CO 2 R 6）C = CHNH-，R 6 = H或C 2 H 5; R 1 = R 5 = H，R 2 = CH 3或CF 3，R 3 R 4 = -CO（CO 2 R 6）C = CHNH-，R 6 = H或 C2H5，以及其药学上可接受的盐。本发明的目的还在于制备新型香豆素喹诺酮羧酸及其生物学作用。

6. 发明公开

EP0817818A1 USE OF SIZED SALTS AS BRIDGING AGENT FOR OIL BASED FLUIDS 失效
标题翻译：时间SALSSPARTIKELN KOLMATIERUNG的粒度分布型油性液体中的应用
公开(公告)号：EP0817818A1
公开(公告)日：1998-01-14
申请号：EP96910544.0
申请日：1996-03-25
申请人： BAKER HUGHES INCORPORATED
发明人： GABRYSCH, Allen , CHESSER, Billy, G.
IPC分类号： C09K8
CPC分类号： C09K8/36 , C09K8/32 , C09K2208/18
摘要： An oil-based fluid system has been discovered using a distribution of salt particle sizes, an oil or water/oil emulsion, a suspending agent for suspending the salt particles in the oil and a filtration control agent. It is important that the salt particles be distributed across a wide size range to effectively prevent filtration or fluid loss into the formation. Since the filter cake particles do not invade the well bore, no high pressure spike occurs during the removal of the filter cake. This high pressure spike indicates damage to the formation and well bore surface, which damage typically reduces overall permeability of the formation. The rheological properties of the fluid allow it to be used in a number of applications where protection of the original permeable formation is desirable. The applications include, but are not limited to, drilling, fracturing and controlling fluid losses during completion operations, such as gravel packing or well bore workovers.

7. 发明公开

EP0783008A3 Coating composition and floor covering including the composition 失效
标题翻译：涂料组合物和含有它们的地板
公开(公告)号：EP0783008A3
公开(公告)日：1998-01-14
申请号：EP96118484.3
申请日：1996-11-18
申请人： Armstrong World Industries, Inc.
发明人： Rosenberry, Angela S. , Rupp, Claude R. , Setthachayanon, Songvit
IPC分类号： C08G18/42 , C08G18/67 , D06N3/14
CPC分类号： C09D175/16 , C08G18/672 , C08G18/6725 , C08G18/7831 , C08G18/7837 , C08G18/792 , C08G18/798 , Y10T428/31551 , C08G18/42
摘要： Floor coverings include a wear layer made from a coat composition including a multifunctional polyurethane (meth)acrylate oligomer. The multifunctional polyurethane is made by reacting a polyisocyanate with a functionality equal or higher than 3, a polyester polyol, and a hydroxyalkyl-(meth)acrylate with a molecular weight of about 116 to about 600. The coating composition preferably includes a reactive (meth)acrylate diluent and a photoinitiator.

8. 发明公开

EP0804946A1 Aerosolbildende Zusammensetzung zum Löschen von Bränden und Verfahren zur Herstellung dieser Zusammensetzung 失效
标题翻译：气溶胶形成组合物灭火和过程本组合物的制备
公开(公告)号：EP0804946A1
公开(公告)日：1997-11-05
申请号：EP97106936.4
申请日：1997-04-25
申请人： R-Amtech International, Inc.
发明人： Kozyrev, Valeriy Nikolaevitch , Yemelyanov, Valeriy Nilovitch , Sidorov, Alexey Ivanovitch , Andreev, Vladimir Andreevitch
IPC分类号： A62D1/06
CPC分类号： A62C5/006 , A62D1/06 , Y10T292/0803
摘要： Die vorliegende Erfindung betrifft eine pyrotechnische, aerosolbildende Zusammensetzung zum Löschen von Bränden in geschlossenen Räumen, enthaltend Kaliumnitrat in einer Menge von 67-72 Masse-%, Phenolformaldehydharz in einer Menge von 8-12 Masse-%, und Dicyandiamid als Rest, wobei die Teilchen des Kaliumnitrats einen mittleren Durchmesser von nicht größer als 25 µm, die des Phenolformaldehydharzes einen mittleren Durchmesser von nicht größer als 100 µm und die des Dicyandiamids einen mittleren Durchmesser von nicht größer als 15 µm besitzen.
Ein weiterer Gegenstand der Erfindung ist ein Verfahren zur Herstellung der Zusammensetzung, die in den üblichen Anlagen gefertigt werden kann, durch Herstellung einer Phenolformaldehydlösung unter Verwendung eines Gemisches von Ethylalkohol mit Aceton in einem Verhältnis von 30-50:70-50 und Vermischen sowie anschließendes Granulieren unter Trocknen bei 20-70°C. Vorzugsweise erfolgt das Trocknen durch Luftumwälzung bei 40°C.
摘要翻译：用于熄灭在封闭的房间火灾烟火，气溶胶形成组合物（I），包含：（A）67-72重量硝酸与不超过25微米的平均粒径（PD）％钾;. （B）8-12％（重量）的苯酚 - 甲醛（PF）树脂具有不超过100微米一个PD。和（C）的双氰胺作为与不超过15微米的PD其余部分。所以声称是生产（Ⅰ）。

9. 发明公开

EP0759457A3 Weather and soiling-resistant silicone-containing coating composition 失效
标题翻译：天气和抗污硅氧烷涂料组合物含有
公开(公告)号：EP0759457A3
公开(公告)日：1997-10-01
申请号：EP96113259.4
申请日：1996-08-19
申请人： SHIN-ETSU CHEMICAL CO., LTD.
发明人： Yamaya, Masaaki, Silicone Denshi Zairyo Gijutsu , Yoshizawa,Masahiro, Silicone Denshi Zairyo Gijutsu
IPC分类号： C08K5/54 , C08L83/04 , C08L101/00
CPC分类号： C09D183/04 , C09D201/00 , C08L83/00
摘要： A coating agent composition comprising:
(A) an organic resin, and (B) a silicone compound represented by the average composition formula (1):
(X) a (Y') b (R 1 ) c SiO (4-a-b-c)/2 (1)
wherein X is a particular functional group containing organic group, Y' is a hydrolyzable group or an admixture of a hydrolyzable group and the silanol group, R 1 is a monovalent hydrocarbon group, a ranges from 0.05 to 0.90, b 0.12 to 1.88, and c 0.10 to 1.00, a + b + c being in the range of 2.02 to 2.67. The amount of the silicon atoms to which said functional group-containing organic group X is bonded is 5 to 90 mol % based on the entire silicon atoms, and the amount of the T unit of R 1 -SiO 3/2 is 10 to 95 mole % based on the entire siloxane units. This composition is useful to form a coating film excellent in weathering resistance, adhesion, stain resistance, scuffing resistance, water resistance and chemical resistance and therefore suitable for protection of articles exposed outdoors.

10. 发明公开

EP0791587A1 Process for the preparation of derivatives of amino-ascorbic acid 失效
标题翻译：制备氨基 - 抗坏血酸衍生物的方法
公开(公告)号：EP0791587A1
公开(公告)日：1997-08-27
申请号：EP97106486.0
申请日：1994-02-04
申请人： PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko drustvo
发明人： Suskovic, Bozidar , Vela, Vanja, Dr. , Buncic, Mira
IPC分类号： C07D307/62 , C07D307/66 , A61K31/34
CPC分类号： A61K31/34 , C07D307/62 , C07D307/66
摘要： The invention relates to a process for the preparation of derivatives of amino-ascorbic acid, their acid and alkali salts.
According to this invention, derivatives of amino-ascorbic acid are prepared by reductive alkylation of amino-ascorbic acid.
摘要翻译：本发明涉及制备氨基 - 抗坏血酸衍生物及其酸和碱盐的方法。根据本发明，通过氨基 - 抗坏血酸的还原烷基化制备氨基 - 抗坏血酸的衍生物。

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