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1. 发明申请

WO2021053342A1 ION MOBILITY SEPARATION DEVICE 审中-公开
公开(公告)号：WO2021053342A1
公开(公告)日：2021-03-25
申请号：PCT/GB2020/052259
申请日：2020-09-17
申请人： MICROMASS UK LIMITED
发明人： HOYES, John Brian
IPC分类号： G01N27/62
摘要： A method of separating ions according to their ion mobility using an ion mobility separation device including a first section and a second section is disclosed, comprising: urging ions through the first section against a first opposing electric field using a first driving force provided by a first set of time varying voltage(s) or voltage waveform(s); progressively reducing the magnitude of the first opposing electric field and/or progressively increasing the magnitude of the first driving force; and driving ions through the second section against a second opposing electric field using a second drive force provided by a second set of time-varying voltage(s) or voltage waveform(s); wherein the magnitude of the second opposing electric field is progressively reduced and/or the magnitude of the second driving force is progressively increased in tandem with reducing the magnitude of the first opposing electric field and/or increasing the magnitude of the first driving force.

2. 发明申请

WO2017182794A1 TRANSFER TUBE CALIBRATION 审中-公开
标题翻译：转移管校准
公开(公告)号：WO2017182794A1
公开(公告)日：2017-10-26
申请号：PCT/GB2017/051080
申请日：2017-04-19
申请人： MICROMASS UK LIMITED
发明人： JONES, Emrys , PRINGLE, Steven Derek
IPC分类号： H01J49/04 , H01J49/16
CPC分类号： H01J49/0422 , H01J49/0404 , H01J49/16
摘要： Disclosed herein is a method comprising liberating analyte material from a sample and transferring the liberated analyte material towards an inlet of an ion analyser via a sampling or transfer tube (202). The presence of the analyte material is detected at a first position by a detector (203), and this detection may be used to determine a transit time for the analyte material through at least a part of said sampling or transfer tube (202). The detector (203) may be disposed within the sampling or transfer tube (202).
摘要翻译：本文公开了一种方法，其包括从样品中释放分析物材料并且将释放的分析物材料经由采样管或输送管（202）朝向离子分析器的入口转移。通过检测器（203）在第一位置处检测分析物材料的存在，并且可以使用该检测来确定分析物材料通过所述采样管或输送管（202）的至少一部分的通过时间。检测器（203）可以设置在采样管或输送管（202）内。

3. 发明申请

WO2020053576A1 ION FILTERING DEVICES 审中-公开
公开(公告)号：WO2020053576A1
公开(公告)日：2020-03-19
申请号：PCT/GB2019/052526
申请日：2019-09-10
申请人： MICROMASS UK LIMITED
发明人： LANGRIDGE, David J. , WILDGOOSE, Jason Lee , GREEN, Martin Raymond , KENNY, Daniel James , GILES, Kevin , PRINGLE, Steven Derek
IPC分类号： G01N27/62 , H01J49/06 , H01J49/42
摘要： A method of filtering ions according to their ion mobility using a device is disclosed, the method comprising a plurality of electrodes and one or more voltage source(s) arranged and adapted to apply voltages to the plurality of electrodes, the method comprising, generating using the one or more voltage source(s) one or more local separation region(s), wherein ions can be separated within each local separation region according to their ion mobility, and moving each local separation region axially along the device with a certain velocity such that, for each local separation region, ions having a value of their ion mobility falling within a selected range are transmitted axially along the device with that local separation region whereas ions having higher and/or lower ion mobility falling outside that range escape the local separation region, wherein any ions that escape the local separation region(s) are removed from within the device and/ or otherwise kept apart from those ions falling within the selected range(s).

4. 发明申请

WO2018073589A1 DUAL MODE MASS SPECTROMETER 审中-公开
标题翻译：双模式质谱分析仪
公开(公告)号：WO2018073589A1
公开(公告)日：2018-04-26
申请号：PCT/GB2017/053155
申请日：2017-10-18
申请人： MICROMASS UK LIMITED
发明人： BROWN, Jeffery Mark
IPC分类号： H01J49/40
CPC分类号： H01J49/405 , H01J49/0031 , H01J49/0036 , H01J49/406 , H01J49/408
摘要： Disclosed herein is an ion analysis instrument comprising a Time of Flight ("TOF") mass analyser comprising a reflectron. The instrument is operable in at least a first mode and a second mode, wherein in said first mode ions are caused to turn around at a first point in the reflectron and wherein in said second mode ions are caused to turn around at a second point in the reflectron such that the distance travelled by ions within the Time of Flight mass analyser is greater in the second mode than the distance travelled by ions within the Time of Flight mass analyser in the first mode. In this way, the operating modes can be selectively optimised for the analysis of ions of different masses.
摘要翻译：本文公开了包括包含反射器的飞行时间（“TOF”）质量分析仪的离子分析仪器。该仪器可在至少第一模式和第二模式下操作，其中在所述第一模式中，使离子在反射器的第一点处转向，并且其中在所述第二模式中，使离子在第二点处转向反射器使得飞行时间质量分析仪内的离子所行进的距离在第二模式中大于在第一模式中飞行时间质量分析仪内的离子所行进的距离。通过这种方式，可以选择性地优化操作模式，以便分析不同质量的离子。

5. 发明申请

WO2022162403A1 GRAPHICS PROCESSORS 审中-公开
公开(公告)号：WO2022162403A1
公开(公告)日：2022-08-04
申请号：PCT/GB2022/050260
申请日：2022-02-01
申请人： ARM LIMITED
发明人： SIDERIS, Isidoros , OYGARD, Tord Kvestad , KJOLL, Per , RUUD, Ole Magnus
IPC分类号： G06T15/00 , G06T11/40
摘要： There is provided a graphics processor (10) comprising a primitive processing circuit operable to process graphics primitives into respective fragment work items to be rendered by a rendering circuit (22). The primitive processing circuit generates one or more queues (18A, 18B) of fragment work items for rendering that contain fragment work items corresponding to multiple, different sources of fragment work items. The graphics processor (10) is configured to issue fragment work items to the rendering circuit (22) in an interleaved fashion such that rendering of fragment work items from a first source of fragment work items can thereby be interleaved with rendering of fragment work items from a second source of fragment work items.

6. 发明申请

WO2021064403A1 ACOUSTIC PARTICLE MANIPULATION 审中-公开
公开(公告)号：WO2021064403A1
公开(公告)日：2021-04-08
申请号：PCT/GB2020/052404
申请日：2020-10-01
申请人： THE UNIVERSITY OF SUSSEX
发明人： SUBRAMANIAN, Sriram , PLASENCIA, Diego Martinez , HIRAYAMA, Ryuji
IPC分类号： G10K15/00
摘要： Disclosed herein is an apparatus comprising a set of acoustic sources controllable to generate an acoustic trap for suspending one or more particle(s) within the volume of the apparatus. The position of the acoustic trap within the volume of the apparatus is changed to cause a particle suspended within the acoustic trap to move around the volume of the apparatus. In particular, the acoustic field defining the acoustic trap is updated at such a rate that the particle is prevented from reaching a static equilibrium position within the acoustic trap. The apparatus may comprise a display apparatus. However, other non- display applications of such apparatus are also disclosed.

7. 发明申请

WO2021038244A1 MASS SPECTROMETER CALIBRATION 审中-公开
公开(公告)号：WO2021038244A1
公开(公告)日：2021-03-04
申请号：PCT/GB2020/052071
申请日：2020-08-28
申请人： MICROMASS UK LIMITED
发明人： DENNY, Richard
IPC分类号： H01J49/00
摘要： Disclosed herein is a method of processing mass spectral data comprising making direct calibration measurements to determine a calibration shift of the mass spectrometry instrument at a calibration time and determining a set of intrinsic ion species that persist across multiple acquisition periods. The direct calibration measurements are then used together with an expected variation in calibration shift as well as the set of intrinsic ion species to calculate the calibration shift of the mass spectrometry instrument at one or more time point(s) of interest other than the calibration time.

8. 发明申请

WO2020115471A1 BIT PLANE ENCODING OF DATA ARRAYS 审中-公开
公开(公告)号：WO2020115471A1
公开(公告)日：2020-06-11
申请号：PCT/GB2019/053416
申请日：2019-12-03
申请人： ARM LIMITED
发明人： SYMES, Dominic Hugo , HUGOSSON, Sven Ola Johannes
IPC分类号： H04N19/132 , H04N19/169 , H04N19/18 , H04N19/34 , H04N19/46 , H04N19/60 , H04N19/176
摘要： Disclosed herein is a method of encoding an array of data elements comprising transforming the array from the spatial to the frequency domain, representing the frequency domain coefficients as a plurality of bit plane arrays, and encoding the set of frequency domain coefficients as a data packet having a fixed size by encoding the bit plane arrays in a bit plane sequence working from the bit plane array representing the most significant bit downwards until the data packet is full. Each bit plane array is encoded by recursively subdividing the bit plane array into respective sections and subsections down to the individual coefficients and including in the data packet, so long as there is available space, data indicating the locations of any (sub)sections in that bit plane array that for the first time in the bit plane sequence contain one or more coefficient(s) having a non-zero bit value.

9. 发明申请

WO2022084666A1 GRAPHICS PROCESSING SYSTEMS 审中-公开
公开(公告)号：WO2022084666A1
公开(公告)日：2022-04-28
申请号：PCT/GB2021/052695
申请日：2021-10-19
申请人： ARM LIMITED
发明人： KAKARLAPUDI, Sandeep , ENGH-HALSTVEDT, Andreas , LANGTIND, Frank Klaeboe
IPC分类号： G06T11/40 , G06T1/20
摘要： Disclosed herein is a method of operating a graphics processor (10) to process sets of geometry to generate an output. Each set of geometry is associated with lower level geometry (72) including vertex data to be used when rendering the geometry as well a separate higher level representation of the geometry (74). The higher level representations of the geometry (74) can be obtained by the graphics processor (10) independently of the other, lower level geometry and used to determine which sets of geometry should be processed for which regions (81) of the output. Once this determination is made, the regions (81) can be rendered by obtaining and processing the lower level geometry (72) accordingly.

10. 发明申请

WO2021014138A1 DECODING MULTIPLEXED MASS SPECTRAL DATA 审中-公开
公开(公告)号：WO2021014138A1
公开(公告)日：2021-01-28
申请号：PCT/GB2020/051729
申请日：2020-07-20
申请人： MICROMASS UK LIMITED
发明人： DENNY, Richard
IPC分类号： H01J49/00
摘要： There is provided a method of decoding a first data set obtained from a time of flight (ToF) mass analyser operating according to an encoded frequency pulsing (EFP) scheme. The method comprises generating a mock data set based on a model set of ions taking account of the EFP pattern and the flight time distribution of the ions. The model set of ions is then iteratively updated using the first data set to determine a second, decoded data set.

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