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1. 外观设计

USD1035200S1 Filter cleaner 有权
公开(公告)号：USD1035200S1
公开(公告)日：2024-07-09
申请号：US29836355
申请日：2022-04-26
申请人： Brad A. English
设计人： Brad A. English
摘要： FIG. 1 is a perspective view of a filter cleaner including six stacked component of decreasing diameters and rounded edges, showing our new design;
FIG. 2 is a front view thereof;
FIG. 3 is a back view thereof;
FIG. 4 is a top view thereof;
FIG. 5 is a bottom view thereof; and,
FIG. 6 is perspective view in an alternate in use configuration.
The broken lines in FIG. 6 are for the purpose of illustrating environmental structure of the filter cleaner, the broken lines form no part of the claimed design.

2. 发明授权

US12019981B2 Method and system for converting literature into a directed graph 有权
公开(公告)号：US12019981B2
公开(公告)日：2024-06-25
申请号：US17344774
申请日：2021-06-10
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人： Mihai Surdeanu , Marco A. Valenzuela Escarcega , Gustave Hahn-Powell , Dane Bell , Thomas Hicks , Enrique Noriega , Clayton Morrison , Rebecca Sharp , Robert Ionut Vacareanu , George Barbosa
IPC分类号： G06F40/211 , G06F3/0482 , G06F16/245 , G06F40/169 , G06F40/253 , G06F40/284 , G06F40/295 , G06F40/30
CPC分类号： G06F40/211 , G06F3/0482 , G06F16/245 , G06F40/169 , G06F40/253 , G06F40/284 , G06F40/295 , G06F40/30
摘要： A machine reading system is described herein that includes a framework in which grammar rules can be developed using a concise language that combines syntax and semantics. The resulting technology thus reduces the development time for new grammars in a new domain. An enormous amount of information appears in the form of natural language across millions of academic papers and other literature sources. For example, in the biological domain, there is a tremendous ongoing effort to extract individual chemical interactions from these texts, but these interactions are only isolated fragments of larger causal mechanisms such as protein signaling pathways. The proposed rule-based event extraction framework can model underlying syntactic representations of events in order to extract signaling pathway fragments. Though application to the biomedical domain is herein described, the framework is domain-independent and is expressive enough to capture most complex events annotated by domain experts.

3. 发明授权

US11965816B2 Use of vibrational spectroscopy for microfluidic liquid measurement 有权
公开(公告)号：US11965816B2
公开(公告)日：2024-04-23
申请号：US17164710
申请日：2021-02-01
申请人： 1087 Systems, Inc.
发明人： Matthias Wagner , John Heanue
IPC分类号： G01N15/14 , B01L3/00 , B07C5/34 , C12N5/071 , G01N15/00 , G01N15/10 , G01N15/1429 , G01N15/1434 , G01N21/17 , G01N21/35 , G01N21/3563 , G01N21/65 , G01N29/24
CPC分类号： G01N15/147 , B01L3/502761 , B07C5/34 , C12N5/0612 , G01N15/14 , G01N15/1427 , G01N15/1429 , G01N15/1434 , G01N15/1436 , G01N15/1459 , G01N15/1475 , G01N15/1484 , G01N21/1702 , G01N21/35 , G01N21/3563 , G01N21/65 , G01N29/2418 , B01L2200/0636 , B01L2200/0652 , B01L2300/0627 , B01L2300/0864 , G01N2015/0065 , G01N2015/1006 , G01N15/1463 , G01N2015/1481 , G01N2015/149 , G01N2015/1493 , G01N2015/1497 , G01N2021/653 , G01N2201/0612
摘要： This disclosure concerns a cytometry system including a handling system that enables presentation of single cells to at least one laser source. The laser source is configured to deliver light to a cell within the cells in order to induce bond vibrations in the cellular DNA. The system further includes a detection facility that detects the signature of the bond vibrations, wherein the bond vibration signature is used to determine the folding or packing of the DNA.

4. 发明授权

US11927590B2 Methods and systems for screening therapeutic compositions for treating age-related macular degeneration 有权
公开(公告)号：US11927590B2
公开(公告)日：2024-03-12
申请号：US17345718
申请日：2021-06-11
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人： Brian S. McKay , Anna G. Figueroa , Nicole R. Congrove
IPC分类号： G01N33/50
CPC分类号： G01N33/5058 , G01N33/502
摘要： Methods and systems for screening therapeutic compositions for the treatment of age-related macular degeneration (AMD) or for the prevention of progression of AMD, wherein retinal pigment epithelium cells (RPE) are cultured and the level of hypoxia-induced exosome release from the RPE cells is subsequently measured. In the present invention, the level of hypoxia-induced exosome release can be correlated with AMD onset and severity.

5. 发明授权

US11851811B2 Artificial leather product and process for producing same 有权
公开(公告)号：US11851811B2
公开(公告)日：2023-12-26
申请号：US17622606
申请日：2020-04-01
申请人： KVADRAT A/S
发明人： Dea Marcela Tuns , Ronni Aakermann Johansen
IPC分类号： D06N3/00 , D06N3/12 , D06N3/14
CPC分类号： D06N3/0011 , D06N3/123 , D06N3/143 , D06N2201/045 , D06N2211/28
摘要： This invention relates to an artificial leather having a laminated structure and a process for producing such product. The artificial leather comprises a non-woven matt formed from bast fibres, more particularly fibres obtained from hemp plants. The fibres in the non-woven matt are impregnated with a polymer, such as a polyester or polyurethane. The artificial leather includes the non-woven matt as a discrete bottom layer in a laminated structure also comprising a discrete intermediate layer of a binder material and a discrete top layer of a polymer coating material.

6. 发明授权

US11840769B2 Guided template based electrokinetic microassembly (TEA) 有权
公开(公告)号：US11840769B2
公开(公告)日：2023-12-12
申请号：US17314708
申请日：2021-05-07
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Lawrence Kulinsky , Tuo Zhou
IPC分类号： C25D1/00 , C25D13/00
CPC分类号： C25D1/006
摘要： The present invention is directed to devices and methods for assembling particulates through the use of non-contact electrokinetic forces applied to polymeric, organic, non-organic, and metallic micro- and nano-particulates in an aqueous solution. The present invention features an electrode comprising a conductive substrate with a layer of photosensitive polymer disposed on it with a plurality of windows etched into the layer. The plurality of windows expose certain portions of the conductive substrate. Applying electric signals to the conductive substrate (e.g. by a function generator) causes materials to attract to only the exposed portions of the conductive substrate. The materials may comprise a plurality of organic, non-organic, and metallic micro- and nano-particulates disposed in an aqueous solution.

7. 发明授权

US11833504B2 Microfluidic label-free isolation and identification of cells using fluorescence lifetime imaging (FLIM) 有权
公开(公告)号：US11833504B2
公开(公告)日：2023-12-05
申请号：US16847305
申请日：2020-04-13
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , PIONEER HI-BRED INTERNATIONAL, INC.
发明人： Abraham P. Lee , Michelle A. Digman , Dohyun Lee , Xuan Li , Ning Ma , Yue Yun
IPC分类号： B01L3/00 , C12N15/10 , C12Q1/02
CPC分类号： B01L3/502761 , B01L3/502715 , C12N15/1003 , C12Q1/02 , B01L2200/0647 , B01L2300/0627 , B01L2300/0816 , B01L2300/0854 , B01L2300/0858 , B01L2300/0864
摘要： Methods and devices for single cell analysis using fluorescence lifetime imaging microscopy (FLIM) are disclosed. The methods utilize microfluidic devices which use traps to immobilize cells for FLIM analysis. The analysed cells may be sorted before or after imaging and may be plant, animal, or bacterial cells. Analysis of the FLIM data may use a phasor plot and may be used to identify a metabolic pattern of the single cells.

8. 发明授权

US11760523B2 Bag emptier device 有权
公开(公告)号：US11760523B2
公开(公告)日：2023-09-19
申请号：US17268556
申请日：2019-08-19
申请人： LOGISTIK WERFRING GMBH
发明人： Marc Werfring , Hans-Joachim Werfring
IPC分类号： B65B69/00 , B25J9/00 , B26D1/06 , B66F9/02 , B65G67/04
CPC分类号： B65B69/0008 , B25J9/0093 , B26D1/06 , B66F9/02 , B65G67/04
摘要： The invention relates to a device for processing dust- and substantially air-tight sacks (1) filled with flowable or free-flowing materials, and for separating the sack material from the sack contents via a collection device (8), wherein the device comprises a sack supply track (4) with a sack removal point (56), a manipulation device (6) with a lifting frame (9) for picking up the filled sacks (1), a sack slitting device (16) for opening the filled sacks (1), a collection device (8) for collecting the sack contents, an empty sack store (12), and an empty pallet store (13).

9. 外观设计

USD995992S1 Brassiere with padding pockets 有权
公开(公告)号：USD995992S1
公开(公告)日：2023-08-22
申请号：US29796257
申请日：2021-06-23
申请人： Katherine Stoltz
设计人： Katherine Stoltz
摘要： FIG. 1 is a front perspective view of a brassiere with padding pockets showing my new design;
FIG. 2 is a back right perspective view thereof showing a right internal pocket opened;
FIG. 3 is a back left perspective view thereof showing a left internal pocket opened;
FIG. 4 is another back right perspective view thereof showing the right internal pocket closed;
FIG. 5 is another back left perspective view thereof showing the left internal pocket closed;
FIG. 6 is a front view thereof;
FIG. 7 is a back view thereof;
FIG. 8 is a right side view thereof;
FIG. 9 is a left side view thereof;
FIG. 10 is a top view thereof;
FIG. 11 is a bottom view thereof; and,
FIG. 12 is another back left perspective view showing the brassiere with padding pockets in use.
The broken lines in FIGS. 1-12 represent portions of the brassiere with padding pockets that form no part of the claimed design.

10. 发明授权

US11690846B2 Folate salts for medical use 有权
公开(公告)号：US11690846B2
公开(公告)日：2023-07-04
申请号：US16651688
申请日：2018-08-29
申请人： APROFOL AG
发明人： Martin Ulmann , Gerd Wiesler , Arthur Bodenmüller , Markus Müller
IPC分类号： A61K31/519 , A61K31/53
CPC分类号： A61K31/519 , A61K31/53
摘要： The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin and phenylethylbiguanidin. The cation is an organic compound with a complementary pharmacological activity.

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