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1. 发明申请

WO2023076685A1 COMPOSITIONS AND METHODS OF CONTROLLING PESTS 审中-公开
公开(公告)号：WO2023076685A1
公开(公告)日：2023-05-04
申请号：PCT/US2022/048452
申请日：2022-10-31
申请人： PERTINENT ECO-SOLUTIONS INC.
发明人： HUBER, Scot Kevin , HATTON, Ronald , JACTEL, Bruno , GEIGLE, William
IPC分类号： A01N65/22 , A01N31/00 , A01N65/28
摘要： Described herein are compositions and methods to be used in controlling pests, such as arthropods, nematodes, helminths, insect pests, internal parasites, and external parasites. Such compositions make use of at least a blend of one or more essential oils and, optionally, additional components, such as surfactants, emulsifiers, solvents, additives, and inerts. Compositions can be applied to a variety of locations to control pests or can also be added into feed or foodstuffs to afford internal pest control.

2. 发明申请

WO2019046685A1 METHOD AND SYSTEM FOR TRACKING A PLURALITY OF ANIMALS WITH A PORTABLE COMPUTING DEVICE 审中-公开
公开(公告)号：WO2019046685A1
公开(公告)日：2019-03-07
申请号：PCT/US2018/049030
申请日：2018-08-31
申请人： MERIAL, INC.
发明人： DELIOU, Pierre-Emmanuel
IPC分类号： G06Q10/08 , G06Q50/02
摘要： A computer-implemented method and system for tracking near-field communication (NFC)-enabled animals with a portable computing device (PCD) (i.e. mobile phone) may include providing an NFC-tag comprising memory in which the memory contains a unique identifier. The NFC-tag may be coupled to an animal and then the NFC-tag may be scanned with the PCD. A tag identification server may determine if data from the NFC-tag exists in a database and then transmits an animal production facility identifier and one or more animal records associated with data from the NFC-tag from the tag identification server if the data from the NFC-tag exists in the database. Access to a secure memory area on the portable computing device containing a complete set of animal records for an entire animal facility may be granted if the software identifier matches the animal production facility identifier received from the tag identification server.

3. 发明申请

WO2017189848A1 LASER ABLATION MACHINE FOR LABELING CRYORENICALLY-FROZEN VIALS 审中-公开
标题翻译：激光烧蚀机用于冷冻冷冻标签
公开(公告)号：WO2017189848A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029840
申请日：2017-04-27
申请人： MERIAL, INC.
发明人： BREHM, Andy , FREEMAN, Dennis, Jerome , SCHINDLER, Ed , CAMPBELL, Julie
IPC分类号： A01N1/02 , B41M5/24
摘要： The invention relates to a machine for labeling "blank-labeled" cryogenically-frozen vials or ampoules, which contain heat-labile biological materials, and to which a laser-light sensitive material had been applied prior to freezing. Accordingly, the machine has been designed to maintain the integrity of the biological materials throughout all phases of the labeling process. The machine generally comprises a master control system; a programmable user interface; a frame; cryogenic freezer assemblies, for keeping the vials at the required low temperatures; an infeed assembly, configured to receive and position blank-labeled cryogenic vials; a cryostatic labeling/quality control tunnel, wherein the vials are maintained at the required temperature, labeled by laser ablation, and checked for quality; and, an outfeed assembly. The machine further comprises a means for transporting the vials from the infeed assembly to the tunnel, and from the tunnel to the outfeed assembly. Vials labeled according to the instant disclosure are ultimately manually or automatically loaded into cryogenic shipping containers.
摘要翻译：本发明涉及一种用于标记“空白标记”的机器，包含热不稳定生物材料的低温冷冻小瓶或安瓿，并且在冷冻之前将激光敏感材料施用于其上。因此，该机器设计用于在贴标过程的所有阶段保持生物材料的完整性。该机器通常包括主控制系统; 一个可编程用户界面; 一个框架; 低温冷冻机组件，用于将小瓶保持在所需的低温下; 进料组件，其配置为接收和定位空白标记的低温小瓶; 低温标记/质量控制隧道，其中小瓶保持在需要的温度，通过激光烧蚀标记，并检查质量; 和一个出料组件。该机器还包括用于将小瓶从进料组件输送到隧道并且从隧道输送到出料组件的装置。根据本公开标记的小瓶最终手动或自动加载到低温运输容器中。

4. 发明申请

WO2017091417A1 VETERINARY FORMULATIONS 审中-公开
标题翻译：兽医配方
公开(公告)号：WO2017091417A1
公开(公告)日：2017-06-01
申请号：PCT/US2016/062364
申请日：2016-11-16
申请人： MERIAL, INC.
发明人： JEANNIN, Philippe
IPC分类号： A01N25/02 , A01N25/30 , A01N47/02 , A01N49/00 , A01N43/40 , A01P7/00 , A01P7/02 , A61K31/415
CPC分类号： A01N47/02 , A61K31/415 , A01N25/02 , A01N25/30 , A01N49/00
摘要： The present invention relates to various topical veterinary compositions comprising fipronil, an insect growth regulator, and a veterinarily acceptable carrier.
摘要翻译：本发明涉及包含氟虫腈，昆虫生长调节剂和兽医学可接受的载体的各种局部兽用组合物。

5. 发明申请

WO2016069983A1 PARASITICIDAL COMPOSITION COMPRISING FIPRONIL 审中-公开
标题翻译：包含FIPRONIL的PARASITICIDAL COMPOSITION
公开(公告)号：WO2016069983A1
公开(公告)日：2016-05-06
申请号：PCT/US2015/058207
申请日：2015-10-30
申请人： MERIAL, INC.
发明人： PATE, James , SHUB, Natalya
IPC分类号： A01N43/40 , A01N47/02 , A01N49/00 , A01P7/00
CPC分类号： A61K31/415 , A01N43/40 , A01N47/02 , A01N49/00 , A61K9/0017 , A61K31/215
摘要： The invention provides for spot-on formulations comprising fipronil in a high concentration for the treatment or prophylaxis of parasites of mammals and birds, and in particular, cats, dogs, horses, chickens, sheep and cattle with the aim of ridding these animals of all the parasites commonly encountered by birds and mammals. The invention also provides for effective and lasting destruction of ectoparasites, such as fleas, ticks, itch mites and lice, and of endoparasites, nematodes, such as filariae, and roundworms of the digestive tract of animals and humans.
摘要翻译：本发明提供了包含高浓度氟虫腈的斑点制剂，用于治疗或预防哺乳动物和鸟类，特别是猫，狗，马，鸡，绵羊和牛的寄生虫，目的是消除所有这些动物鸟类和哺乳动物常遇到寄生虫。本发明还提供了有效和持久的破坏外寄生物，例如跳蚤，蜱，螨和虱，以及动物和人的消化道的寄生虫，线虫如丝丝虫和蛔虫。

6. 发明申请

WO2015175672A1 METHODS FOR FREEZE-DRYING AND REHYDRATING BIOLOGICS 审中-公开
标题翻译：冷冻干燥和再生生物学方法
公开(公告)号：WO2015175672A1
公开(公告)日：2015-11-19
申请号：PCT/US2015/030588
申请日：2015-05-13
申请人： MERIAL, INC. , VITAMFERO S.A
发明人： GENIN, Noel Yves Henri Jean , AUDONNET, Jean-Christophe , ROY, Didier , SECHE, Edouard , GERVAIS, Patrick , KHALDI-PLASSART, Samira , USEO, Romain , DE CONINCK, Joëlle
IPC分类号： A01N1/02 , A61K39/002 , A61K9/19
CPC分类号： A61K39/002 , A01N1/02 , A01N1/0221 , A01N1/0278 , A01N1/0284 , A61K9/0019 , A61K9/19 , A61K2039/522 , Y02A50/41 , Y02A50/412
摘要： The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for freeze-drying biological preparations, including peptides, antigens, antibodies, and especially, cells. Importantly, the disclosed methods preserve the viability, infectivity and immunogenicity of cells from the Apicomplexa phylum, the Sarcocystidae family, and in particular, cells from the Toxoplasma genus.
摘要翻译：本发明一般涉及免疫学和疫苗技术领域。更具体地，本发明涉及用于冷冻干燥生物制剂的方法，包括肽，抗原，抗体，特别是细胞。重要的是，所公开的方法保留了Apicomplexa门，Sarcocystidae家族，特别是来自弓形虫属细胞的细胞的活力，感染性和免疫原性。

7. 发明申请

WO2015066277A1 ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS 审中-公开
标题翻译：抗生素和杀虫剂ISOXAZOLINE化合物
公开(公告)号：WO2015066277A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063074
申请日：2014-10-30
申请人： MERIAL LIMITED
发明人： MENG, Charles, Q.
IPC分类号： C07D413/10 , A01N43/50 , A01N43/54 , A01N43/60 , C07D413/12 , A61P33/00
CPC分类号： C07D413/12 , A01N43/80 , C07D413/10 , C07D413/14
摘要： The present invention relates to novel and inventive isoxazoline of formula (I) and salts thereof: wherein wherein variables D 1, D 2 , D 3 , D 4 , D 5 , R 1 , B 1 , B 2 , B 3 , R 2 , R 3 , R 4 , R 5 , R 6 , Y, Z, L, a and b are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
摘要翻译：本发明涉及式（I）的新颖和本发明的异恶唑啉及其盐：其中其中变量D1，D2，D3，D4，D5，R1，B1，B2，B3，R2，R3，R4，R5，R6，Y 这里描述的Z，L，a和b如说明书中所定义。本发明还涉及包含式（I）的异恶唑啉化合物，其制备方法及其用于预防或治疗动物中的寄生虫感染或侵染以及作为农药的杀虫剂和杀虫剂组合物。

8. 发明申请

WO2015051371A3 HAEMOPHILUS PARASUIS VACCINE SEROVAR TYPE FOUR 审中-公开
公开(公告)号：WO2015051371A3
公开(公告)日：2015-04-09
申请号：PCT/US2014/059330
申请日：2014-10-06
申请人： MERIAL LIMITED
发明人： LAWRENCE, Paulraj, Kirubakaran , BEY, Russell, F.
IPC分类号： A61K39/102 , C12R1/21
摘要： The present invention is a Haemophilus parasuis vaccine against serovar type 4 capable of triggering a protective immune response when administered to pigs as a killed vaccine. The present invention is also a method for vaccinating swine against Haemophilus parasuis infection, serovar type 4, by a) clonally propagating one or more cells which are capable of triggering an immune response against Haemophilus parasuis infection, serovar type 4, that protects the pig against Haemophilus parasuis infection, and b) combining an immunologically effective amount of the cells with a veterinarily acceptable carrier in a form suitable for administration as a vaccine to the pig, and c) administering as a killed vaccine. The cell culture is from a pathogenic parent strain.

9. 发明申请

WO2014164697A1 REVERSE GENETICS SCHMALLENBERG VIRUS VACCINE COMPOSITIONS, AND METHODS OF USE THEREOF 审中-公开
标题翻译：逆转录病毒草甘膦疫苗组合物及其使用方法
公开(公告)号：WO2014164697A1
公开(公告)日：2014-10-09
申请号：PCT/US2014/023243
申请日：2014-03-11
申请人： MERIAL LIMITED
发明人： MINKE, Jules, Maarten
IPC分类号： A61K39/12 , C07K14/00 , C12N7/00 , C12N15/86
CPC分类号： C12N7/00 , A61K39/12 , A61K2039/5252 , A61K2039/552 , A61K2039/55505 , A61K2039/55566 , A61K2039/55577 , C12N2760/12021 , C12N2760/12034
摘要： The present invention relates to compositions comprising replication defective Schmallenberg virus vaccines, methods of producing the vaccines, and the administration of such vaccines to animals, including ovines and bovines. The invention further relates to methods for providing long-term protective immunity against Schmallenberg in animals, including ovines and bovines.
摘要翻译：本发明涉及包含复制缺陷型Schmallenberg病毒疫苗的组合物，生产疫苗的方法，以及向动物（包括羊和牛）施用这种疫苗。本发明还涉及在动物中提供对Schmallenberg的长期保护性免疫的方法，包括羊和牛。

10. 发明申请

WO2014121064A1 METHOD FOR TREATING AND CURING LEISHMANIOSIS USING FEXININDAZOLE 审中-公开
标题翻译：使用FEXININDAZO治疗和治愈感冒的方法
公开(公告)号：WO2014121064A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014134
申请日：2014-01-31
申请人： MERIAL LIMITED
发明人： POLLMEIER, Matthias , BLAIR, Jeffrey, Jynn
IPC分类号： A61K31/4164 , A61P33/02
CPC分类号： A61K31/4164
摘要： The present invention encompasses methods of using fexinidazole to treat and eliminate and/or cure L. infantum infections in canines.
摘要翻译：本发明包括使用替硝唑治疗和消除和/或治愈犬科的婴幼儿感染的方法。

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