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1. 发明申请

WO2023031592A1 METHODS FOR DETERMINING AND/OR MONITORING THE HEALTH STATUS OF FISH 审中-公开
公开(公告)号：WO2023031592A1
公开(公告)日：2023-03-09
申请号：PCT/GB2022/052209
申请日：2022-08-30
申请人： WELLFISH DIAGNOSTICS LIMITED
发明人： QUINN, Brian M , BARISIC, Josip , REZVY, Shahadate
IPC分类号： G01N33/68
摘要： The present invention relates to methods for determining the health status of populations of fish and diagnosing conditions or diseases in unhealthy fish. In particular, the present invention relates to blood biomarkers for assessing the health status and diagnosing conditions and diseases in populations of fish.

2. 发明申请

WO2022269269A1 REGULATORY NUCLEIC ACID SEQUENCES 审中-公开
公开(公告)号：WO2022269269A1
公开(公告)日：2022-12-29
申请号：PCT/GB2022/051611
申请日：2022-06-23
申请人： SYNPROMICS LIMITED , ASKLEPIOS BIOPHARMACEUTICAL, INC.
发明人： YANEZ-CUNA, Jorge Omar , IGLESIAS, Juan Manuel , COOPER, Sinclair , ROBERTS, Michael L. , EVRIPIOTI, Antonia
IPC分类号： C12N15/86 , A61K48/00 , A61K48/005 , A61K48/0058 , C12N2750/14143 , C12N2830/008 , C12N2830/15
摘要： The present invention relates to regulatory nucleic acid sequences, in particular muscle- specific promoters, elements thereof, and other such nucleic acid sequences, that are capable of enhancing muscle-specific expression of genes. The invention also relates to expression constructs, vectors and cells comprising such muscle-specific regulatory nucleic acid sequences, and to methods of their use. The regulatory nucleic acid sequences are of particular utility for gene therapy applications, but also find utility in other areas such as bioprocessing and biotechnology.

3. 发明申请

WO2022185046A1 SUB-ZERO PHASE CHANGE MATERIALS WITH MULTIPLE CRYSTALLISATION EVENTS 审中-公开
公开(公告)号：WO2022185046A1
公开(公告)日：2022-09-09
申请号：PCT/GB2022/050541
申请日：2022-03-02
申请人： SUNAMP LIMITED
发明人： ODLING, Gylen , FISHER, Kate , OLIVER, David , BISSELL, Andrew
IPC分类号： C09K5/06
摘要： There is disclosed herein compositions of sub-zero salt-water eutectic phase change materials which exhibit two crystallisation processes on cooling. Furthermore, there is disclosed additives which can be used to alter the phase change transitions of one or more of these crystallisation processes.

4. 发明申请

WO2022013571A1 A MANUFACTURING PROCESS TO ENHANCE SURFACE MOUNT SOLDER PAD JOINT FORMATION VIA A LASER SUBTRACTIVE METHOD 审中-公开
公开(公告)号：WO2022013571A1
公开(公告)日：2022-01-20
申请号：PCT/GB2021/051834
申请日：2021-07-16
申请人： SHAW, Fraser Murray
发明人： SHAW, Fraser Murray
IPC分类号： H05K3/26 , H05K3/34
摘要： The present invention relates to the field of electronic assembly for the manufacture of electronic products such as mobile phones, where electronic components such as resistors and capacitors and microprocessors are joined to a bare circuit board to form a complete electronics device and relates to the preparation of attachment locations on a bare circuit board

5. 发明申请

WO2021191628A1 FORSKOLIN-INDUCIBLE PROMOTERS AND HYPOXIA-INDUCIBLE PROMOTERS 审中-公开
公开(公告)号：WO2021191628A1
公开(公告)日：2021-09-30
申请号：PCT/GB2021/050743
申请日：2021-03-26
申请人： SYNPROMICS LIMITED , ASKLEPIOS BIOPHARMACEUTICAL, INC.
发明人： WHYTESIDE, Graham , TORRANCE, Victoria, Fiona , ROBERTS, Michael, L.
IPC分类号： C12N15/63 , A61K48/00 , C12N15/79 , C12N15/86 , C12N2750/14143 , C12N2750/14152 , C12N2830/002
摘要： The present invention relates to forskolin-inducible and hypoxia-inducible cis-regulatory elements, promoters and vectors, and methods of their use.

6. 发明申请

WO2021148765A1 CONDUIT ANCHOR 审中-公开
公开(公告)号：WO2021148765A1
公开(公告)日：2021-07-29
申请号：PCT/GB2020/053207
申请日：2020-12-14
申请人： ORBITAL MARINE POWER LIMITED
发明人： MILLER, Calum , BYERS, Mark
IPC分类号： E02D27/52 , E21B17/01 , B63B21/04 , E21B17/017 , E21B41/08 , E21B43/0107 , F03B17/06 , F16L1/16 , F16L1/20 , F16L1/201
摘要： Disclosed is conduit anchor, an offshore system comprising a conduit anchor and a method of deployment. The conduit anchor includes a base section adapted for attachment to a conduit, and a conduit guide extending from the base section. In use a dynamic conduit extends along a dynamic conduit pathway range defined by the anchor, via the conduit guide. The conduit guide comprises a convex bend protecting surface region oriented towards the dynamic conduit pathway range which in use protects against over bending of the dynamic conduit.

7. 发明申请

WO2021064357A1 ORAL FILMS AND A METHODS FOR THE MANUFACTURE AND DELIVERY THEREOF 审中-公开
公开(公告)号：WO2021064357A1
公开(公告)日：2021-04-08
申请号：PCT/GB2020/052348
申请日：2020-09-29
申请人： BIOFILM LIMITED
发明人： CULLEN, John Edward , CRICHTON, Robert , LIVINGSTONE, Mark Alexander
IPC分类号： A61K9/00 , A61K9/70 , A61K31/352 , A61K47/32 , A61K47/36 , A61K47/38
摘要： The present invention provides an oral film. The oral film comprises two or more film forming polymers comprising pullulan and at least one further film forming polymer, the two or more film forming polymers present in a total amount of from about 18% to about 80% by weight; a cannabinoid composition present in a total amount of from about 5% to about 60% by weight; water present in an amount of from about 3% to about 15% by weight; each of the foregoing amounts being based on the total weight of the oral film; and wherein the film has a thickness of from about 50 pm to about 500 pm and wherein the cannabinoid oil is present in an amount of at least 0.15 mg per mm3 of film. Methods of providing such an oral film and methods of applying it to an oral or buccal cavity are also provided herein.

8. 发明申请

WO2020245782A1 METHOD OF WETTING LOW SURFACE ENERGY SUBSTRATE AND A SYSTEM THEREFOR 审中-公开
公开(公告)号：WO2020245782A1
公开(公告)日：2020-12-10
申请号：PCT/IB2020/055306
申请日：2020-06-05
申请人： W. L. GORE & ASSOCIATES, INC.
发明人： AGAPOV, Alexander L.
IPC分类号： H01M8/1023 , H01M8/1039 , H01M8/106 , H01M8/1081 , H01M8/1018
摘要： There is provided a method of wetting a low surface energy substrate with a high surface tension liquid comprising at least the steps of providing a low surface energy substrate having a surface energy in the range of from 15 to 45 mN/m, a high surface tension liquid having a surface tension in the range of from greater than 25 to 70 mN/m and a low surface tension fluid having a surface tension in the range of from 10 to 25 mN/m; contacting the low surface energy substrate with the high surface tension liquid; contacting at least one of the low surface energy substrate and the high surface tension liquid with the low surface tension fluid vapour, either before, at the same time as or after the contacting of the low surface energy substrate with the high surface tension liquid; and removing the low surface tension fluid vapour from the low surface energy substrate. The high surface tension liquid can be used as a carrier liquid for a coating material, such as an ion exchange material, to be deposited on the substrate, such as ePTFE, in a method of coating. Also disclosed is a system for such coating methods.

9. 发明申请

WO2020245614A1 SPORTING APPARATUS AND INDUSTRIAL PRODUCTS 审中-公开
公开(公告)号：WO2020245614A1
公开(公告)日：2020-12-10
申请号：PCT/GB2020/051388
申请日：2020-06-08
申请人： MCCUAIG, Ronald
发明人： MCCUAIG, Ronald
IPC分类号： A63B49/08 , A63B53/14 , A63B60/06 , A63B60/14 , A63B60/18
摘要： There is herein described a range of sporting products comprising sucker elements, which can be used in various uses such as on products which require, for example, hand or any other type of grip contact. The grip contact may be with the feet or hands (or any other part of the body). The sporting products that the grips may be used on may comprise rackets (e.g. for tennis/badminton/squash etc.), bats (e.g. cricket/baseball/table-tennis etc.), bicycles, motorcycles, golf clubs, water sports (surfing, windsurfing) etc. The sucker elements may also be included with other sporting product such as on the inside and/or outside of running sock or shoes for example. There is also described a range of industrial products comprising sucker elements which can be used in a range of applications such as on a range of vehicle parts (e.g. bus rails, train rails, boat rails, steering wheels, motorbike handles and foot pegs etc.), industrial machinery (e.g. handles for tools such as drills, pneumatic drills etc.), flooring (e.g. decking on boats and in industrial environments), crockery, bathroom and shower flooring, and surfaces to aid disabled people.

10. 发明申请

WO2020148555A1 LIVER-SPECIFIC INDUCIBLE PROMOTERS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2020148555A1
公开(公告)日：2020-07-23
申请号：PCT/GB2020/050107
申请日：2020-01-20
申请人： SYNPROMICS LIMITED
发明人： ROBERTS, Michael , WHYTESIDE, Graham , BRAE, Anne
IPC分类号： C12N15/79 , A61K48/00 , C12N15/86
摘要： The present invention relates to inducible regulatory elements, promoters and vectors, especially gene therapy vectors, and methods of their use.

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