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1. 发明申请

WO2011129684A1 METHOD FOR ESTABLISHING AND PREDICTING RESISTANCE OR RESPONSIVENESS TO CHEMOTHERAPY USING PEPTIDE MASS PROFILE 审中-公开
标题翻译：使用肽质量配置文件建立和预测耐药性或反应性化学疗法的方法
公开(公告)号：WO2011129684A1
公开(公告)日：2011-10-20
申请号：PCT/NL2010/050198
申请日：2010-04-15
申请人： ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM , UMAR, Arzu , FOEKENS, Johannes Albert , LUIDER, Theo, Marten
发明人： UMAR, Arzu , FOEKENS, Johannes Albert , LUIDER, Theo, Marten
IPC分类号： G01N33/574 , G01N33/68
CPC分类号： G01N33/6851 , G01N33/57415
摘要： Title: Method for establishing and predicting resistance or responsiveness to chemotherapy using peptide mass profile Abstract Method to predict responsiveness or resistance to chemotherapy in breast cancer comprising providing an optionally processed sample from a breast cancer patient as a test sample, wherein the sample comprise peptides and/or proteins; subjecting the test sample to MALDI- FT-ICR mass spectrometry to generate mass spectra for individual peptide mass in the sample and to quantify the amount of the individual peptide mass present in the test sample; and comparing the amount of an individual peptide mass present in the test sample with the amount of a corresponding peptide mass in a reference sample, wherein the peptide masses are selected from the peptide masses as identified in table 1 and 2
摘要翻译：标题：使用肽质量分布建立和预测化疗的抗药性或反应性的方法摘要用于预测乳腺癌化疗反应性或耐药性的方法，包括从乳腺癌患者提供任选处理的样品作为测试样品，其中样品包含肽和 /或蛋白质; 使测试样品进行MALDI-FT-ICR质谱以产生样品中单个肽质量的质谱，并定量测试样品中存在的单个肽质量的量; 并将测试样品中存在的单个肽质量与参考样品中相应肽质量的量进行比较，其中肽质量选自表1和表2所示的肽质量

2. 发明申请

WO2011054390A1 METHOD AND SYSTEM FOR FORWARDING A MESSAGE IN A SESSION INITIATION PROTOCOL BASED COMMUNICATIONS NETWORK 审中-公开
标题翻译：基于会话启动协议的通信网络中的消息传递方法和系统
公开(公告)号：WO2011054390A1
公开(公告)日：2011-05-12
申请号：PCT/EP2009/064714
申请日：2009-11-05
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (publ) , DEN HARTOG, Jos , NOLDUS, Rogier August Caspar Joseph
发明人： DEN HARTOG, Jos , NOLDUS, Rogier August Caspar Joseph
IPC分类号： H04L29/08 , H04L29/06
CPC分类号： H04L45/42 , H04L65/1006 , H04L65/1016 , H04L65/1046 , H04L65/1073 , H04L67/327
摘要： Method and system for forwarding a message in a Session Initiation Protocol, SIP, based communications network, to a first and second SIP user equipment of a subscriber via a controller server and one of a plurality of traffic handler servers. The first user equipment may have first capabilities different from second capabilities of the second user equipment. The controller server receives the message; determines which first traffic handler server of the plurality of traffic handler servers is arranged for providing a first service associated with the first capabilities, and which second traffic handler server of the plurality of traffic handler servers is arranged for providing a second service associated with the second capabilities; and forwards the message to the first user equipment via the first traffic handler server, and to the second user equipment via the second traffic handler server.
摘要翻译：用于经由控制器服务器和多个交通处理程序服务器中的一个将在基于SIP的通信网络中的消息转发到用户的第一和第二SIP用户设备的方法和系统。第一用户设备可以具有与第二用户设备的第二能力不同的第一功能。控制器服务器接收消息; 确定多个交通处理服务器中的哪个第一交通处理服务器被安排用于提供与第一能力相关联的第一服务，以及多个交通管理服务器中的哪个第二交通处理服务器被安排用于提供与第二服务相关联的第二服务能力; 并经由第一话务处理服务器将该消息转发给第一用户设备，经由第二话务处理服务器转发给第二用户设备。

3. 发明申请

WO2011031134A1 IMAGE PROCESSING METHOD AND SYSTEM 审中-公开
标题翻译：图像处理方法和系统
公开(公告)号：WO2011031134A1
公开(公告)日：2011-03-17
申请号：PCT/NL2009/050549
申请日：2009-09-14
申请人： ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM , NIESSEN, Wiro Joep , METZ, Cornelis Timotheüs , VAN WALSUM, Theodores , SCHAAP, Michiel
发明人： NIESSEN, Wiro Joep , METZ, Cornelis Timotheüs , VAN WALSUM, Theodores , SCHAAP, Michiel
IPC分类号： G06T7/00 , G06T3/00
CPC分类号： G06T3/0068 , G06T7/344 , G06T7/38 , G06T2207/10076 , G06T2207/10081 , G06T2207/10116 , G06T2207/10124 , G06T2207/30048 , G06T2207/30101
摘要： Registration of two dimensional images with a time dependent three dimensional model of a moving object such as the heart is performed using two transformations. A first transformation, which may involve deformation, maps a three dimensional model of the object for one time point, such as the end- systolic heart phase, to mapped models that match 3D scans of the object for different time points. The first transformation is determined by matching 3D scans with mapped 3D models, typically using large scale structures of the object. Afterwards a stream of 2D images, such as X-ray images of the object, is captured for a series of time points. From this stream, second transformations are determined that map the mapped 3D models to the 2D images. The parameters of the second transformation for an individual time point are determined dependent on the 2D images for a plurality of the time points, to ensure that these parameters map the mapped 3D models for plurality of time points to registered 3D models that define derived 2D image data that match the combination of 2D images for the plurality of time points. Thus, instead of using a single spatial transformation to register the 3D models with a 2D image, registration is performed using a reference 3D model and a combination of a first and second spatial transformation.
摘要翻译：使用两个变换来执行诸如心脏的移动物体的时间依赖三维模型的二维图像的注册。可能涉及变形的第一个变换将对象的三维模型（例如收缩末期心脏相位）映射到与不同时间点的对象的3D扫描匹配的映射模型。通过将3D扫描与映射的3D模型进行匹配来确定第一个变换，通常使用对象的大规模结构。之后，一系列时间点捕获2D图像流，例如对象的X射线图像。从该流中，确定将映射的3D模型映射到2D图像的第二变换。根据多个时间点的2D图像确定各个时间点的第二变换的参数，以确保这些参数将多个时间点的映射3D模型映射到定义导出的2D图像的注册3D模型与多个时间点的2D图像的组合相匹配的数据。因此，不是使用单个空间变换来使用2D图像来注册3D模型，而是使用参考3D模型和第一和第二空间变换的组合来执行注册。

4. 发明申请

WO2011031133A1 METHOD OF ROUTING A CALL TO ONE OF A PLURALITY OF USER EQUIPMENT 审中-公开
标题翻译：呼叫一个多用户设备的方法
公开(公告)号：WO2011031133A1
公开(公告)日：2011-03-17
申请号：PCT/NL2009/050548
申请日：2009-09-11
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) , BOT, Johannes Jan , DEN BROK, Antoine , MAAS, Fedor
发明人： BOT, Johannes Jan , DEN BROK, Antoine , MAAS, Fedor
IPC分类号： H04W40/20
CPC分类号： H04W40/20 , H04W84/045
摘要： Method of routing a call to one of a plurality of user equipment of a UMA/GAN- subscriber in a telecommunications network. The telecommunications network comprises a service control entity. Said service control entity determines whether said UMA/GAN- subscriber is within or outside a home area. The service control entity comprises a first indicator indicating at least one network address of a user equipment comprised by the plurality of user equipment to which the call is to be routed in case the UMA/GAN- subscriber is within the home area, and a second indicator indicating at least one network address of a user equipment comprised by the plurality of user equipment to which the call is to be routed in case the UMA/GAN- subscriber is outside the home area.
摘要翻译：将电话路由到电信网络中的UMA / GAN用户的多个用户设备之一的方法。电信网络包括业务控制实体。所述服务控制实体确定所述UMA / GAN用户是否在家庭区域内或外部。服务控制实体包括第一指示符，其指示在UMA / GAN用户在归属区域内的情况下由呼叫要被路由的多个用户设备所包括的用户设备的至少一个网络地址，以及第二指示符指示器，其指示在UMA / GAN用户在家庭区域之外的情况下呼叫将被路由的多个用户设备所包括的用户设备的至少一个网络地址。

5. 发明申请

WO2011021926A1 REGULATING THE AMINO ACID POOL USED FOR THE ACUTE-PHASE PROTEIN SYNTHESIS 审中-公开
标题翻译：调节用于急性期蛋白质合成的氨基酸池
公开(公告)号：WO2011021926A1
公开(公告)日：2011-02-24
申请号：PCT/NL2009/050506
申请日：2009-08-21
申请人： N.V. NUTRICIA , VAN NORREN, Klaske , PETERS, Johannes Adrianus Cornelis , LANSINK, Mirian
发明人： VAN NORREN, Klaske , PETERS, Johannes Adrianus Cornelis , LANSINK, Mirian
IPC分类号： A23L1/30 , A23L1/305 , A61K31/195 , A61K31/202
CPC分类号： A61K31/202 , A23L33/10 , A23L33/12 , A23L33/17 , A23L33/175 , A23L33/18 , A23V2002/00 , A61K31/198 , A61K2300/00 , A23V2200/324 , A23V2250/0642 , A23V2250/0606 , A23V2250/0616 , A23V2250/0628 , A23V2250/0626 , A23V2250/0654 , A23V2250/1882 , A23V2200/304 , A23V2200/308
摘要： The present invention is directed at a combination of amino acids for use in the therapeutic or prophylactic treatment of an imbalance in acute-phase protein synthesis. In accordance with the invention protein catabolism, associated with acute-phase protein synthesis may be reduced. Further, the invention relates to a specific nutritional composition, comprising a combination of specific amino acids.
摘要翻译：本发明涉及用于治疗或预防性治疗急性期蛋白质合成不平衡的氨基酸的组合。根据本发明，可以减少与急性期蛋白质合成相关的蛋白质分解代谢。此外，本发明涉及特定营养组合物，其包含特定氨基酸的组合。

6. 发明申请

WO2011005098A1 PEPTIDE LIGANDS FOR TARGETING TO THE BLOOD-BRAIN BARRIER 审中-公开
标题翻译：用于靶向血脑屏障的肽配体
公开(公告)号：WO2011005098A1
公开(公告)日：2011-01-13
申请号：PCT/NL2010/050448
申请日：2010-07-12
申请人： ABBOTT HEALTHCARE PRODUCTS B.V. , UNIVERSITEIT LEIDEN , UNIVERSITEIT UTRECHT HOLDING B.V. , VAN ROOY, Inge , HENNINK, Wilhelmus Everhardus , MASTROBATTISTA, Enrico , SCHIFFELERS, Raymond Michel , DINTER-HEIDORN, Heike , BRINKHUIS, Rene Pascal , VAN HEST, Jan , RUTJES, Floris Peter Johannes Theodorus
发明人： VAN ROOY, Inge , HENNINK, Wilhelmus Everhardus , MASTROBATTISTA, Enrico , SCHIFFELERS, Raymond Michel , DINTER-HEIDORN, Heike , BRINKHUIS, Rene Pascal , VAN HEST, Jan , RUTJES, Floris Peter Johannes Theodorus
IPC分类号： C07K7/08 , A61K47/48
CPC分类号： B82Y5/00 , A61K47/66 , A61K47/6911 , A61K47/6915 , C07K7/08 , C07K2319/01
摘要： The present invention relates to peptides comprising defined amino acid sequences, compositions comprising said peptides and a pharmaceutically acceptable substance, use of said peptides as a central nervous system targeting principle in the treatment, prophylaxis or diagnosis of a central nervous system disorders, combinations of said peptides with pharmaceutically acceptable substances, use of said combinations for the treatment, prophylaxis or diagnosis of a central nervous system disorders, a method of delivery of said peptide and of a pharmaceutically acceptable substance and a nucleic acid sequence encoding for said peptide sequence.
摘要翻译：本发明涉及包含确定的氨基酸序列的肽，包含所述肽的组合物和药学上可接受的物质，所述肽用作中枢神经系统靶向原理在治疗，预防或诊断中枢神经系统疾病中的用途，所述具有药学上可接受的物质的肽，所述组合用于治疗，预防或诊断中枢神经系统病症，递送所述肽和药学上可接受的物质的方法以及编码所述肽序列的核酸序列。

7. 发明申请

WO2011005095A1 A METHOD OF ENCAPSULATING A FLEXIBLE OPTOELECTRONIC MULTI-LAYERED STRUCTURE 审中-公开
标题翻译：一种柔性光电多层结构的封装方法
公开(公告)号：WO2011005095A1
公开(公告)日：2011-01-13
申请号：PCT/NL2010/050442
申请日：2010-07-09
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO , KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN DER WEIJER, Peter , VAN MOL, Antonius Maria Bernardus , TANASE, Cristina
发明人： VAN DER WEIJER, Peter , VAN MOL, Antonius Maria Bernardus , TANASE, Cristina
IPC分类号： H01L51/52
CPC分类号： H01L51/5259 , H01L51/5253 , H01L51/5256
摘要： The invention relates to a method of encapsulating a flexible optoelectronic multi-layered structure (6) provided on a polymer substrate (2) comprising the steps of providing the flexible optoelectronic multi-layered structure with one or both a bottom encapsulation stack (B) and a top encapsulation stack (T), wherein the bottom encapsulation stack and the top encapsulation layer comprise a first inorganic layer (4a, 8a) separated from a second inorganic layer (4b, 8b) by a substantially continuous getter layer (5, 8) comprising a metal oxide, the first and the second inorganic layers having an intrinsic water vapour transmission of 1O -5 g.m -2. day -1 or less.
摘要翻译：本发明涉及一种封装设置在聚合物基板（2）上的柔性光电多层结构（6）的方法，包括以下步骤：向柔性光电多层结构提供底部封装叠层（B）和顶部封装堆叠（T），其中底部封装堆叠和顶部封装层包括通过基本上连续的吸气剂层（5,8）与第二无机层（4b，8b）分离的第一无机层（4a，8a）包含金属氧化物，所述第一和第二无机层的固有水蒸气透过率为10-5m2m2·day-1或更低。

8. 发明申请

WO2011002287A1 APPARATUS AND METHOD FOR SEALING OR TYING PRODUCTS 审中-公开
标题翻译：密封或类型产品的装置和方法
公开(公告)号：WO2011002287A1
公开(公告)日：2011-01-06
申请号：PCT/NL2010/050408
申请日：2010-06-29
申请人： DUOSEAL AUTOMATICS B.V. , AARTS, Guido Maurinus Adriana Maria
发明人： AARTS, Guido Maurinus Adriana Maria
IPC分类号： B65B67/06 , B65B51/06 , B65B27/10 , B65B25/02
CPC分类号： B65B51/065 , B65B25/02 , B65B25/023 , B65B27/105 , B65B51/06 , B65B67/06
摘要： Apparatus (1) for sealing flexible bags, comprising a gathering assembly for a neck of the bag including at least a transport means and at least one tape dispenser (3,40), wherein the gathering assembly comprises a star wheel (4) and the tape dispenser comprises a guide for guiding tape from the tape dispenser over part of the star wheel, the transport means extending into or along at least a cell of the star wheel, wherein the star wheel is coupled to the transport means, such that when the transport means is driven, feeding the neck of the bag into a cell of the star wheel, the star wheel is driven intermittently.
摘要翻译：用于密封柔性袋的装置（1），包括用于所述袋的颈部的聚集组件，其包括至少一个输送装置和至少一个胶带分配器（3,40），其中所述聚集组件包括星形轮（4）和胶带分配器包括用于将胶带从胶带分配器引导到星轮的一部分上的引导件，输送装置延伸到星形轮的至少一个单元中或沿其中的至少一个单元，其中星形轮联接到输送装置，使得当运输装置被驱动，将袋子的颈部进入星轮的电池中，星轮间歇地驱动。

9. 发明申请

WO2010151135A1 FLOOR ASSEMBLY 审中-公开
标题翻译：地板总成
公开(公告)号：WO2010151135A1
公开(公告)日：2010-12-29
申请号：PCT/NL2010/050405
申请日：2010-06-28
申请人： INFRA+ B.V. , VAN GROEN, Hendrik Diederik Willem
发明人： VAN GROEN, Hendrik Diederik Willem
IPC分类号： E04B5/10 , E04B5/48
CPC分类号： E04B5/48 , E04B5/10
摘要： The invention relates to a floor assembly provided with at least one plate, and at least two beams connected to the plate and extending parallel to each other. With the aid of the beams, at least two sections can be supported such that with the aid of the two sections, a detachable panel can be supported. Between the two beams, at least one bearing section is attachable, on which bearing section at least the two sections are attachable.
摘要翻译：本发明涉及一种设置有至少一个板的地板组件，以及至少两个梁，其连接到板并且彼此平行地延伸。借助于梁，可以支撑至少两个部分，使得借助于两个部分，可以支撑可拆卸的面板。在两个梁之间，可附接至少一个轴承部分，至少两个部分可承载在该轴承部分上。

10. 发明申请

WO2010151131A3 APPARATUS FOR DETECTING VIABLE MICROORGANISMS OR SPORES IN A SAMPLE AND USE THEREOF. 审中-公开
公开(公告)号：WO2010151131A3
公开(公告)日：2010-12-29
申请号：PCT/NL2010/050398
申请日：2010-06-25
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO , DUISTERWINKEL, Antonie Ellert , SANDTKE, Marijn , KORT, Remco , LEXMOND, Axel Sebastiaan
发明人： DUISTERWINKEL, Antonie Ellert , SANDTKE, Marijn , KORT, Remco , LEXMOND, Axel Sebastiaan
IPC分类号： C12M1/34
摘要： The present invention relates to the field of microbiology, more particular to an apparatus for detecting viable microorganisms or spores in a sample. Provided is an apparatus comprising an inlet for said sample, a sample immobilization area, a container comprising a composition comprising a phototautomeric compound, a light source and a detection unit. Also provided are the use of such an apparatus for detecting at least one viable microorganism in a sample, and the use of such an apparatus for detecting at least one viable spore in a sample.

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