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1. 发明申请

WO2022180374A2 TENSION MONITORING APPARATUS 审中-公开
公开(公告)号：WO2022180374A2
公开(公告)日：2022-09-01
申请号：PCT/GB2022/050457
申请日：2022-02-18
申请人： JR DYNAMICS LIMITED
发明人： LOWRY, Steve , ROSINSKI, Tomasz , ROSINSKI, Krzysztof , ROSINSKI, Jarek
IPC分类号： G01L5/24 , G01L1/22 , G01L1/2218
摘要： Disclosed herein is a tension monitoring apparatus. The apparatus comprises a fixing with a shank which in use is under tension, a strain sensor embedded in the shank of the fixing and configured to generate a strain sensor signal corresponding to tension in the shank. The apparatus further comprises a data processing means configured to receive the strain sensor signal, process the strain sensor signal in accordance with one or more characterising parameters associated with the strain sensor and thereby generate corresponding strain sensor data indicative of a strain to which the shank is subject. Additionally, the apparatus comprises a wireless transmitter for communicating the strain sensor data to a remote receiver, wherein the data processing means and the wireless transmitter are mounted in a module fixed to an end of the fixing.

2. 发明申请

WO2022157499A1 PROTECTED HDAC (HISTONE DEACETYLASE) INHIBITORS 审中-公开
公开(公告)号：WO2022157499A1
公开(公告)日：2022-07-28
申请号：PCT/GB2022/050157
申请日：2022-01-20
申请人： LIGHTOX LIMITED
发明人： WHITING, Andrew , CHISHOLM, David , PUJOL, Alba
IPC分类号： C07D417/14 , C07D409/10 , C07D407/10 , C07D333/24 , A61K31/381 , A61K31/496 , A61P35/00
摘要： The invention relates to protected HDAC inhibitor compounds of formula I, in which Y, Ar1, Ar2, X, R1 and R2 are as defined herein. In aspects, the inventions relates to use of the compounds, and to methods of deprotecting the compounds.

3. 发明申请

WO2022084656A1 INTEGRATED THERMAL CONDITIONING AND PCR IN A MOLECULAR POC DIAGNOSTIC SYSTEM 审中-公开
公开(公告)号：WO2022084656A1
公开(公告)日：2022-04-28
申请号：PCT/GB2021/052667
申请日：2021-10-14
申请人： QUANTUMDX GROUP LIMITED
发明人： JOWSEY, Molly , SELBY, Matthew
IPC分类号： B01L7/00 , B01L3/00 , C12Q1/6844 , C12Q1/70
摘要： The present invention relates to integration of molecular testing methodologies onto point of care (POC) diagnostic devices and systems and methods of molecular testing based on the same. More particularly it relates to microfluidic test cassettes or chips that are received within a POC diagnostic device and which are able to directly test biological samples that have had no or minimal processing to remove PCR inhibitor. The invention allows on-cassette/on- chip processing within the size confines of the cassette/chip by utilising the same heating zone for multiple processing steps.

4. 发明申请

WO2021116699A1 REVERSIBLY INHIBITED BINDING MOLECULES 审中-公开
公开(公告)号：WO2021116699A1
公开(公告)日：2021-06-17
申请号：PCT/GB2020/053183
申请日：2020-12-11
申请人： PRECISION IMMUNOTHERAPEUTICS LIMITED
发明人： SELF, Colin H , COLE, William Gwyn
IPC分类号： C07K16/28 , A61P35/00 , C12N15/115 , A61K39/395
摘要： Reversibly inhibited antibodies are disclosed, suitable for treatment of diseases such as cancer. The reversibly inhibited antibodies are such that they regain their activity on illumination, for example with UV light. Compositions containing such antibodies, methods of preparation of such antibodies and methods of use of such antibodies are also disclosed. The moiety employed to provide reversible inhibition may comprise a hydrophilic polymer such as polyethylene glycol.

5. 发明申请

WO2021032694A1 WALL FIXING 审中-公开
公开(公告)号：WO2021032694A1
公开(公告)日：2021-02-25
申请号：PCT/EP2020/073020
申请日：2020-08-17
申请人： LOADFIX LIMITED
发明人： PECKITT, Darren Ashley
IPC分类号： F16B13/00 , F16B13/12 , F16B21/07
摘要： Disclosed is a wall fixing for securing an item to a cavity wall. The wall fixing comprises a body (101) comprising a body aperture extending between a first end and a second end of the body. The body further comprises a wall plug aligning element (107,108), the wall plug aligning element (107,108) adapted to hold a wall plug on an axis (104) defined by the body aperture.

6. 发明申请

WO2020144454A1 OLIGONUCLEOTIDE DEPOSITION ONTO POLYPROPYLENE SUBSTRATES 审中-公开
公开(公告)号：WO2020144454A1
公开(公告)日：2020-07-16
申请号：PCT/GB2019/053633
申请日：2019-12-19
申请人： QUANTUMDX GROUP LIMITED
发明人： HANNANT, Jennifer , FLEMING, Jodie Leanne
IPC分类号： C12Q1/6834 , C12Q1/6876
摘要： The invention relates to a method of immobilising an oligonucleotide on a polypropylene surface. In embodiments, the invention relates to a method of immobilising labelled ssDNA on a polypropylene surface for use in a hybridisation assay.

7. 发明申请

WO2020128494A1 SYSTEM AND METHOD FOR REUSABLE DIGITAL VIDEO TEMPLATES INCORPORATING CUMULATIVE SEQUENTIAL ITERATION TECHNIQUE IN MUSIC EDUCATION 审中-公开
公开(公告)号：WO2020128494A1
公开(公告)日：2020-06-25
申请号：PCT/GB2019/053638
申请日：2019-12-19
申请人： LEWIS, John Eric
发明人： LEWIS, John Eric
IPC分类号： G09B15/00 , G09B5/06 , G06Q50/20 , G09B15/08
摘要： Disclosed is a method of presenting a media file enabling a user to emulate musical content therein. The media file comprises a plurality of segments, each segment representing a demonstration of at least part of a musical phrase comprising one or more musical notes of a piece of music. The method comprises presenting a first segment of the plurality of segments for emulation by the user. The method further comprises subsequently presenting the first segment followed by a second segment of the plurality of segments for emulation by the user. The method further comprises subsequently presenting the previously presented segments followed by additional segments until all of the plurality of segments have been presented for emulation by the user.

8. 发明申请

WO2020115477A1 METHOD AND APPARATUS FOR MEASURING LIGHT INTENSITY FOR IMAGING 审中-公开
公开(公告)号：WO2020115477A1
公开(公告)日：2020-06-11
申请号：PCT/GB2019/053424
申请日：2019-12-04
申请人： CORTIRIO LIMITED
发明人： BELDON, Patrick John , MACEY, Paul David
IPC分类号： G01J1/44 , G01J1/42 , G01J3/28
摘要： A method of measuring light intensity for imaging using a light detector array comprising a plurality of light detectors, each light detector of the plurality of light detectors arranged to generate an output corresponding to an intensity of incident light. The method comprises, in a first measurement mode: controlling the light detector array to generate a first plurality of output signals, each output signal of the first plurality of output signals generated by one of a plurality of groups of proximate light detectors of the light detector array, each group of proximate light detectors comprising a first light detector and second light detector forming a light detector pair, each output signal of the first plurality of output signals corresponding to a difference between the light intensity detected by the light detectors of the group of proximate light detectors, and generating a light intensity measurement for each group from each received output signal of the first plurality of output signals, the method further comprising, in a second measurement mode: controlling the light detector array to generate a second plurality of output signals, each output signal of the second plurality of output signals generated by one of the light detectors, and generating a light intensity measurement for each light detector from each received output signal of the second plurality of output signals.

9. 发明申请

WO2020048895A1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF 审中-公开
公开(公告)号：WO2020048895A1
公开(公告)日：2020-03-12
申请号：PCT/EP2019/073290
申请日：2019-08-31
申请人： THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN
发明人： EVANS, Rachel , COMBY, Steve
IPC分类号： A61B5/145 , A61B5/1455 , G01P5/00 , G01K11/20 , G01K13/02 , C09D11/50 , C09K11/06 , C09K11/07
摘要： The invention relates to a luminescence-based colorimetric sensor formulation and method of use thereof. The sensor formulation can be used to assess oxygen concentration, particularly in controlled oxygen atmospheres such as food packaging. In embodiments, the invention also relates to sensor-containing laminate films for food packaging, and methods of their preparation.

10. 发明申请

WO2019202294A1 FIXATION DEVICE 审中-公开
公开(公告)号：WO2019202294A1
公开(公告)日：2019-10-24
申请号：PCT/GB2019/050919
申请日：2019-03-29
申请人： SIMON BERRY OPTOMETRIST LTD
发明人： BERRY, Simon
IPC分类号： A61B3/00 , A61B3/113
摘要： The present invention relates to aids or devices with optical elements which include a partially reflective surface, which allow examination or recordal of a patient who is fixated on a visual target, with said examination or recordal occurring along the same axis as the line of sight. The invention also allows for a target more personalised and customised to the patient's needs.

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