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1. 发明申请

WO2018102747A1 APPARATUSES, SYSTEMS AND METHODS FOR IMAGING MICRO-OBJECTS 审中-公开
公开(公告)号：WO2018102747A1
公开(公告)日：2018-06-07
申请号：PCT/US2017/064308
申请日：2017-12-01
申请人： BERKELEY LIGHTS, INC.
发明人： LUNDQUIST, Paul , LEBEL, Paul , JESS, Phillip Ronald, Thomas
IPC分类号： B01L3/00 , G01J3/44 , G01N1/40 , G01N21/64 , G02B21/06 , G02B21/36
摘要： The present disclosure relates to an optical apparatus for imaging and/or manipulating micro- objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The first tube lens can be configured to capture the structured light beams transmitted by the structured light modulator. The second tube lens can be configured to transmit image light beams from the dichroic beam splitter to the image sensor. The image sensor can be configured to receive image light beams from the second tube lens. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.

2. 发明申请

WO2017189926A1 ADAPTIVE COMPRESSION THERAPY SYSTEMS AND METHODS 审中-公开
标题翻译：自适应压缩治疗系统和方法
公开(公告)号：WO2017189926A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029971
申请日：2017-04-27
申请人： RADIAL MEDICAL, INC.
发明人： JOHNSON, Eric , FOGARTY, Thomas , LUCATERO, Sylvester , LAROYA, Gilbert , WALL, James , SALINAS, Conrad
IPC分类号： A61F5/01 , A61F5/04 , A61H1/02 , A61H9/00 , A61H15/00
摘要： Systems, devices and methods for providing active and/or passive compression therapy to a body part can include a compression device worn over a compression stocking. The compression device can have a pulley based drive train that is driven by a motor to tighten and loosen compression elements, such as compression straps, in a precise, rapid, and balanced manner. Sensors can be used in the compression device and/or compression stockings to provide feedback to modulate the compression treatment parameters.
摘要翻译：用于向身体部位提供主动和/或被动压缩治疗的系统，设备和方法可以包括穿戴在压缩袜子上的压缩设备。压缩装置可以具有基于滑轮的传动系，该传动系由马达驱动，以精确，快速和平衡的方式收紧和松开诸如压缩带的压缩元件。传感器可用于压缩装置和/或压缩袜中以提供反馈以调节压缩治疗参数。

3. 发明申请

WO2016044739A1 MATRIX IMPLANT 审中-公开
标题翻译： MATRIX植物
公开(公告)号：WO2016044739A1
公开(公告)日：2016-03-24
申请号：PCT/US2015/050966
申请日：2015-09-18
申请人： SI-BONE INC.
发明人： SCHNEIDER, Bret W. , SIMON, Roxanne , LINDSEY, Derek , YERBY, Scott A.
IPC分类号： A61B17/58 , A61F2/30 , A61F5/00
CPC分类号： A61B17/84 , A61B17/7055 , A61F2/44 , A61F2002/2839 , A61F2002/30115 , A61F2002/30149 , A61F2002/30154 , A61F2002/30156 , A61F2002/30171 , A61F2002/30604 , A61F2002/30995 , A61F2002/4495
摘要： Implants for the fusion or fixation of two bone segments are described. For example, the implants can be used for the fusion or fixation of the sacroiliac joint. The implants can have a matrix structure, have a rectilinear cross-sectional area, and have a curvature.
摘要翻译：描述了用于两个骨段的融合或固定的植入物。例如，植入物可用于骶髂关节的融合或固定。植入物可以具有矩阵结构，具有直线横截面积并具有曲率。

4. 发明申请

WO2016044731A1 IMPLANTS FOR BONE FIXATION OR FUSION 审中-公开
标题翻译：用于骨固定或融合的植入物
公开(公告)号：WO2016044731A1
公开(公告)日：2016-03-24
申请号：PCT/US2015/050951
申请日：2015-09-18
申请人： SI-BONE INC.
发明人： REILEY, Mark, A. , SCHNEIDER, Bret, W. , LEUNG, Joanne , SAND, Paul , YERBY, Scott, A.
IPC分类号： A61B17/58 , A61F2/30 , A61F5/00
CPC分类号： A61B17/1757 , A61B17/1604 , A61B17/84 , A61F2/44 , A61F2002/30156 , A61F2002/30171 , A61F2002/30879 , A61F2002/30884 , A61F2002/30995
摘要： Implants for the fusion or fixation of two bone segments are described. For example, the implants can be used for the fusion or fixation of the sacroiliac joint. The implants can include fenestrations, have a rectilinear overall cross-sectional area, and have a curvature. Some implants can also be used to rescue failed implants.
摘要翻译：描述了用于两个骨段的融合或固定的植入物。例如，植入物可用于骶髂关节的融合或固定。植入物可以包括开窗，具有直线整体横截面积，并具有曲率。一些植入物也可用于挽救失败的植入物。

5. 发明申请

WO2015131056A2 WAVEGUIDE-BASED DETECTION SYSTEM WITH SCANNING LIGHT SOURCE 审中-公开
标题翻译：扫描光源的基于波导的检测系统
公开(公告)号：WO2015131056A2
公开(公告)日：2015-09-03
申请号：PCT/US2015/018032
申请日：2015-02-27
申请人： INDX LIFECARE, INC.
发明人： DUER, Reuven
IPC分类号： C12M1/36
CPC分类号： G01N21/6452 , G01N21/6428 , G01N21/645 , G01N33/54373 , G01N2021/6484
摘要： The invention provides methods and devices for generating optical pulses in one or more waveguides using a spatially scanning light source. A detection system, methods of use thereof and kits for detecting a biologically active analyte molecule are also provided. The system includes a scanning light source, a substrate comprising a plurality of waveguides and a plurality of optical sensing sites in optical communication with one or more waveguide of the substrate, a detector that is coupled to and in optical communication with the substrate, and means for spatially translating a light beam emitted from said scanning light source such that the light beam is coupled to and in optical communication with the waveguides of the substrate at some point along its scanning path. The use of a scanning light source allows the coupling of light into the waveguides of the substrate in a simple and cost-effective manner.
摘要翻译：本发明提供了使用空间扫描光源在一个或多个波导中产生光脉冲的方法和设备。还提供了检测系统，其使用方法和用于检测生物活性分析物分子的试剂盒。该系统包括扫描光源，包括与基底的一个或多个波导光学通信的多个波导和多个光学感测位置的基底，耦合到基底并与基底光学连通的检测器，用于在空间上平移从所述扫描光源发射的光束，使得所述光束在沿着其扫描路径的某点处与所述衬底的波导耦合并且与所述衬底的波导光学通信。扫描光源的使用允许以简单和成本有效的方式将光耦合到衬底的波导中。

6. 发明申请

WO2013106713A1 RETRIEVAL SNARE DEVICE AND METHOD 审中-公开
标题翻译：检索设备和方法
公开(公告)号：WO2013106713A1
公开(公告)日：2013-07-18
申请号：PCT/US2013/021241
申请日：2013-01-11
申请人： VOLCANO CORPORATION
发明人： LAROYA, Gilbert , DO, Paul , JOHNSON, Eric
IPC分类号： A61B17/221 , A61B17/22 , A61F2/01
CPC分类号： A61B17/221 , A61F2/01 , A61F2002/011
摘要： The present invention relates generally to devices and methods for retrieving or manipulating objects within a lumen. More specifically, embodiments of the invention relate to devices and methods for retrieving or manipulating medical devices from a body lumen. One embodiment of the present invention provides a novel and improved retrieval snare and method of fabricating and using the same. The snare includes a snare wire, having a distal end and a proximal end, for use in the human anatomy, such as but not limited to blood vessels, pulmonary airways, reproductive anatomy, gastrointestinal anatomy, and organs such as the kidneys or lungs. The device enables a user to capture a foreign object located within the human anatomy, grasp said object in a controlled manner, and retrieve and remove said object from the human anatomy.
摘要翻译：本发明一般涉及用于检索或操纵管腔内的物体的装置和方法。更具体地，本发明的实施例涉及用于从体腔取回或操纵医疗装置的装置和方法。本发明的一个实施例提供了一种新颖和改进的检索圈套及其制造和使用方法。该圈套包括具有远端和近端的圈套，用于人体解剖结构，例如但不限于血管，肺气道，生殖解剖结构，胃肠道解剖结构以及器官如肾或肺。该装置使得用户能够捕获位于人体解剖结构内的异物，以受控的方式掌握所述物体，并从人体解剖结构检索和移除所述物体。

7. 发明申请

WO2013096872A1 FETAL MONITORING DEVICE AND METHODS 审中-公开
标题翻译： FET监测装置及方法
公开(公告)号：WO2013096872A1
公开(公告)日：2013-06-27
申请号：PCT/US2012/071428
申请日：2012-12-21
申请人： LIFEWAVE, INC.
发明人： TUPIN, Joe, Paul, Jr. , TUPIN, Joe, Paul , STEPHANSEN, Stephan, IV
IPC分类号： A61B8/02 , H04B7/24 , G06F19/00
CPC分类号： A61B5/7246 , A61B5/02411 , A61B5/0507 , A61B5/4362 , A61B5/7282 , A61B8/56 , A61B8/565
摘要： Described herein are fetal and/or maternal monitoring devices, systems and methods using UWB medical radar. These devices and systems may include a UWB sensor providing high-resolution and reliable simultaneous monitoring of multiple indicators of fetal and/or maternal health, such as fetal heart rate, fetal heart rate variability, fetal respiration, fetal gross body movement, maternal contractions, maternal heart rate, maternal respiration, and other derivative parameters during virtually all stages of pregnancy and during delivery. The sensor allows novel collection of physiological data using a single sensor or multiple sensors to develop individual and aggregate normal motion indices for use in determining when departure from normal motion index is indicative of fetal or maternal distress.
摘要翻译：这里描述的是使用UWB医疗雷达的胎儿和/或母体监测装置，系统和方法。这些设备和系统可以包括提供高分辨率和可靠的同时监测胎儿和/或母亲健康的多个指标的UWB传感器，例如胎儿心率，胎儿心率变异性，胎儿呼吸，胎儿体重总体运动，母亲收缩，产妇心率，母亲呼吸和其他衍生参数在几乎所有阶段的怀孕和交付期间。传感器允许使用单个传感器或多个传感器来新鲜收集生理数据，以开发个体和聚集的正常运动指数，以用于确定何时离开正常运动指数表示胎儿或母亲的痛苦。

8. 发明申请

WO2013090903A1 CATHETER SECUREMENT DEVICES 审中-公开
标题翻译：导管器保护装置
公开(公告)号：WO2013090903A1
公开(公告)日：2013-06-20
申请号：PCT/US2012/070120
申请日：2012-12-17
申请人： TELEFLEX INCORPORATED
发明人： HYMAN, Daniel , NODA, Wayne, A. , BELL, Stephen, G.
IPC分类号： A61M25/02 , A61F13/02
CPC分类号： A61M25/02 , A61F13/0216 , A61M2025/024 , A61M2025/0253 , A61M2025/0266 , A61M2025/028
摘要： Described herein are catheter securement devices that can be used to secure catheters, catheter hubs and other medical devices to the body of a patient. The catheter securement devices can include an adhesive pad and engagement tabs with downwardly extending posts that can engage the holes in suture tabs located on the catheter hub. Adaptors can be used to provide suture tabs to catheters that lack suture tabs.
摘要翻译：这里描述的是可用于将导管，导管套和其它医疗装置固定到患者身体的导管固定装置。导管固定装置可以包括粘合垫和具有向下延伸的柱的接合突片，其可以接合位于导管座上的缝线接头中的孔。适配器可用于向没有缝合片的导管提供缝线。

9. 发明申请

WO2018191194A1 ENRICHMENT AND IDENTIFICATION OF FETAL MATERIAL 审中-公开
公开(公告)号：WO2018191194A1
公开(公告)日：2018-10-18
申请号：PCT/US2018/026780
申请日：2018-04-10
申请人： RARECYTE, INC.
发明人： CHOW, Jennifer, Christa
IPC分类号： C12N15/10 , C12Q1/68 , G01N1/28 , G01N1/34 , G01N1/40 , G01N33/48 , G01N33/50 , G01N33/52
CPC分类号： G01N33/56966 , C12Q1/6883 , G01N1/4077 , G01N33/74 , G01N2333/705 , G01N2333/71 , G01N2333/988
摘要： This disclosure is directed to a kit and method for retrieving a target material, such as fetal material, from a sample, such as a maternal sample or fraction thereof. An enrichment agent can be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent can be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.

10. 发明申请

WO2014152461A3 SYSTEMS AND METHODS FOR MAKING A LAMINAR VENTRICULAR PARTITIONING DEVICE 审中-公开
标题翻译：用于制造层状心室分隔装置的系统和方法
公开(公告)号：WO2014152461A3
公开(公告)日：2014-09-25
申请号：PCT/US2014/027364
申请日：2014-03-14
申请人： CARDIOKINETIX, INC.
发明人： ALEXANDER, Miles D.
IPC分类号： A61B17/12
摘要： Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components (14) are jointed at a hub (12) to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet (11) into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.
摘要翻译：本文描述了用于将聚合物片材固定到框架结构的肋部件的系统和方法，其中肋部件（14）在轮毂（12）处接合以形成可扩张和可折叠的植入物。通常，该方法可以包括减小框架结构的直径的步骤; 将所述框架结构放置到组装夹具中，其中所述组装夹具被配置为将所述框架结构保持在具有减小的直径的加载构造中; 将聚合物片材（11）放入组装夹具中; 并在压力下加热组件以将片材熔合到框架结构。通常，固定装置可以包括第一和第二台板，该第一和第二台板具有成形部分和围绕台板周边定位的边缘部分，其中成形部分构造成将框架结构的肋部件保持在加载构造中，直径。

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