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1. 发明申请

WO2022202732A1 CELL CULTURING SYSTEM 审中-公开
公开(公告)号：WO2022202732A1
公开(公告)日：2022-09-29
申请号：PCT/JP2022/012948
申请日：2022-03-22
申请人： TERUMO KABUSHIKI KAISHA , TERUMO BCT, INC.
发明人： IGARASHI, Masatsugu , OHASHI, Hirotaka , GLOOR, Andrew
IPC分类号： C12M1/00 , C12M3/00 , C12M1/12 , C12M1/34 , C12M1/36
摘要： The cell culturing system (10) is equipped with a plurality of processing units (24) that perform culturing of cells, a plurality of reactor installation devices (68) in which the plurality of processing units (24) are capable of being respectively installed, a plurality of connection circuits (26) connected respectively to the plurality of processing units (24), a plurality of circuit control devices (66) which the plurality of connection circuits (26) are capable of being respectively attached to and detached from, and a sensor device (70). The sensor device (70) is used in common with respect to the plurality of processing units (24), in order to measure components of the culture medium guided into the plurality of processing units (24). Each of the plurality of processing units (24) includes a plurality of bioreactors (30).

2. 发明申请

WO2022181448A1 MEDICATION ADMINISTRATION DEVICE 审中-公开
公开(公告)号：WO2022181448A1
公开(公告)日：2022-09-01
申请号：PCT/JP2022/006445
申请日：2022-02-17
申请人： TERUMO KABUSHIKI KAISHA
发明人： MATSUMOTO, Fumiya
IPC分类号： A61M5/20 , A61M5/32 , A61M5/50
摘要： A medication administration device (10) includes a cap (18) detachably disposed at a distal end of a cover sleeve (14). The cap (18) includes outer hooks (150) engageable with engagement holes (120) of the cover sleeve (14) and configured to restrict movement of the cap (18) toward a distal end. A casing (12) has an inner peripheral surface provided with recesses (28) that house the outer hooks (150) when the outer hooks (150) are inclined radially outward. The recesses (28) are disposed closer to the distal end than the outer hooks (150) in a state where the cover sleeve (14) moves toward a proximal end relative to the casing (12).

3. 发明申请

WO2022004624A1 MEDICAL BAG SYSTEM AND CENTRIFUGAL SEPARATION SYSTEM 审中-公开
公开(公告)号：WO2022004624A1
公开(公告)日：2022-01-06
申请号：PCT/JP2021/024274
申请日：2021-06-28
申请人： TERUMO KABUSHIKI KAISHA
发明人： YAMAZAKI, Yuusuke
IPC分类号： A61M1/36 , A61J1/10 , A61M1/0218 , A61M1/3693
摘要： A medical bag system (10) and a centrifugal separation system (136) are equipped with a main bag (46) in which blood is accommodated, a blood plasma bag (48) in which blood plasma is accommodated, a chemical solution bag (50) in which a red blood cell preservative solution is accommodated, and a transfer tube (52) connecting the main bag (46), the blood plasma bag (48), and the chemical solution bag (50). The chemical solution bag (50) includes a port side end portion (58) having a connection port (72) to which the transfer tube (52) is connected, a suspended side end portion (60), which is an end portion opposite to the port side end portion (58), and which is formed with a suspension hole (64) through which a suspension hook (112) is inserted, and further including extension members (66) that project out in a tongue shape from side portions of the suspension hole (64).

4. 发明申请

WO2021161927A1 CELL CULTURING SYSTEM, SENSOR KIT, AND METHOD OF DETERMINING LIFESPAN OF ENZYME SENSOR 审中-公开
公开(公告)号：WO2021161927A1
公开(公告)日：2021-08-19
申请号：PCT/JP2021/004386
申请日：2021-02-05
申请人： TERUMO KABUSHIKI KAISHA
发明人： IGARASHI, Masatsugu
IPC分类号： C12M1/12 , C12M1/00 , C12M1/34 , C12M1/36 , C12Q1/00
摘要： A cell culturing system (22) includes an enzyme sensor (124) that detects a concentration of a predetermined component of a culture medium used for culturing of cells, a sensor flow path (46B2) in which the enzyme sensor (124) is disposed, and a bioreactor (20) that performs culturing of cells while causing the culture medium to flow through the sensor flow path (46B2), and further includes a deterioration index calculation unit (138) that determines a deterioration index of the enzyme sensor (124), based on a detected concentration value of the enzyme sensor (124), and a detection period during which the detected concentration value is detected, and a lifespan determination unit (140) that detects whether or not an integrated value of the deterioration index has reached a threshold value, and thereby determines the lifespan of the enzyme sensor (124).

5. 发明申请

WO2018062211A1 BLOOD BAG SYSTEM AND BLOOD TREATMENT METHOD 审中-公开
标题翻译：血袋系统和血液处理方法
公开(公告)号：WO2018062211A1
公开(公告)日：2018-04-05
申请号：PCT/JP2017/034813
申请日：2017-09-26
申请人： TERUMO KABUSHIKI KAISHA
发明人： IGARASHI, Masatsugu
IPC分类号： A61M1/02
摘要： Provided are a blood bag system and a blood treatment method capable of securely and efficiently obtaining buffy coat having a sufficiently low content rate of platelet poor plasma. In a blood bag system (10) used for a blood treatment method, in a transfer completed state in which whole blood in a first bag (12) is centrifuged to transfer blood plasma to a second bag (14) through a first transfer tube (24) and transfer red cell concentrates to a third bag (16) through a second transfer tube (26), a buffy coat is left in the first bag (12). In the transfer completed state, when a platelet additive solution is transferred from a fourth bag (18) to the first bag (12) on which a centrifugal force acts through a third transfer tube (28), blood plasma in the buffy coat is discharged from the first bag (12).
摘要翻译：本发明提供一种血袋系统和血液处理方法，该血袋系统和血液处理方法能够可靠且有效地获得具有足够低血小板贫血浆含量的血沉棕黄层。在用于血液处理方法的血袋系统（10）中，在第一袋（12）中的全血被离心分离以通过第一输送管（14）将血浆输送到第二袋（14）的输送完成状态 24），并通过第二输送管（26）将红细胞浓缩物输送到第三袋（16）中，在第一袋（12）中留下淡黄层。在传送完成状态下，当血小板添加剂溶液从第四袋（18）转移到通过第三传送管（28）作用离心力的第一袋（12）时，血沉棕黄层中的血浆被排出从第一个包（12）。

6. 发明申请

WO2016199373A1 FLUID PRESSURE CYLINDER 审中-公开
标题翻译：流体压力缸
公开(公告)号：WO2016199373A1
公开(公告)日：2016-12-15
申请号：PCT/JP2016/002635
申请日：2016-06-01
申请人： SMC CORPORATION
发明人： SUZUKI, Yasunaga , FUKUI, Chiaki , YAEGASHI, Makoto
IPC分类号： F15B15/14
CPC分类号： F15B15/1438
摘要： On inner wall surfaces (14b, 16b) of a head cover (14) and a rod cover (16) of a fluid pressure cylinder (10), respective pluralities of first and second spigot pins (36, 80) are installed so as to project out from the inner wall surfaces (14b, 16b). The first and second spigot pins (36, 80) are disposed on circumferences of a predetermined diameter that internally contact or inscribe the cylinder tube (12). In addition, when the cylinder tube (12) is assembled with respect to the head cover (14) and the rod cover (16), by the flange members (38) of the first and second spigot pins (36, 80) inscribing the inner circumferential surface thereof, the cylinder tube (12) is positioned and assembled coaxially with respect to the centers of the head cover (14) and the rod cover (16).
摘要翻译：在头盖（14）的内壁表面（14b，16b）和流体压力缸（10）的杆盖（16）之间安装有多个第一和第二插口销（36,80），以便从内壁表面（14b，16b）突出。第一和第二插口销（36,80）设置在内部接触或内接缸筒（12）的预定直径的周长上。此外，当缸套（12）相对于头盖（14）和杆盖（16）组装时，由第一和第二插销（36,80）的凸缘构件（38,80）缸套（12）的内圆周表面相对于头罩（14）和杆盖（16）的中心同轴地定位和组装。

7. 发明申请

WO2015125841A1 CLAMP APPARATUS 审中-公开
标题翻译：夹钳装置
公开(公告)号：WO2015125841A1
公开(公告)日：2015-08-27
申请号：PCT/JP2015/054505
申请日：2015-02-12
申请人： SMC CORPORATION
发明人： FUKUI, Chiaki , TAKAHASHI, Kazuyoshi , SASAKI, Hideki , KOBAYASHI, Masaharu
IPC分类号： B25B5/08 , B25B5/04 , B25B5/06 , B25B5/12 , B25B5/16
CPC分类号： B25B5/16 , B25B5/064 , B25B5/087
摘要： A clamp apparatus (10) includes a pair of first and second clamp arms (14, 16) supported rotatably on a body (12). The clamp apparatus (10) also includes a manual release mechanism (22) capable of manually releasing a clamped state in the case that an output from a drive unit (18) to the first and second clamp arms (14, 16) is stopped and the clamped state of a workpiece (W) is locked. The manual release mechanism (22) includes a release lever (68) disposed rotatably on a first plate body (26). By an operator operating the release lever (68) to thereby rotate the release lever (68), a block body (52) of a driving force transmission mechanism (20) is pressed and moved upwardly, and pressing forces applied to the first and second clamp arms (14, 16) in widthwise outside directions thereof by a pair of rollers (58a, 58b), are released. Consequently, gripping members (36) of the first and second clamp arms (14, 16) are rotated in directions away from each other to thereby cause an unclamped state.
摘要翻译：夹持装置（10）包括可旋转地支撑在主体（12）上的一对第一和第二夹紧臂（14,16）。夹具装置（10）还包括手动释放机构（22），其能够在从驱动单元（18）到第一和第二夹持臂（14,16）的输出停止的情况下手动释放夹紧状态;以及工件（W）的夹紧状态被锁定。手动释放机构（22）包括可旋转地设置在第一板体（26）上的释放杆（68）。通过操作释放杆（68）的操作者以使释放杆（68）旋转，驱动力传递机构（20）的块体（52）被向上推压并施加到第一和第二通过一对辊（58a，58b）在宽度方向外侧的夹持臂（14,16）被释放。因此，第一和第二夹紧臂（14,16）的夹紧构件（36）沿彼此远离的方向旋转，从而导致松开状态。

8. 发明申请

WO2015008808A1 FUEL CELL MODULE 审中-公开
标题翻译：燃料电池模块
公开(公告)号：WO2015008808A1
公开(公告)日：2015-01-22
申请号：PCT/JP2014/068970
申请日：2014-07-10
申请人： HONDA MOTOR CO., LTD.
发明人： YOSHIMINE, Yuki , OGAWA, Tetsuya
IPC分类号： H01M8/04 , H01M8/06
CPC分类号： H01M8/0618 , H01M8/04022 , H01M8/04074 , H01M8/0625 , H01M8/1246 , H01M2008/1293 , H01M2250/20 , H01M2300/0071 , Y02T90/32
摘要： A fuel cell module (12) includes a fuel cell stack (24) and FC peripheral equipment (38). In the fuel cell module (12), a stress relaxing portion (124) for relaxing heat stress is provided at least along a boundary between a central area and one of outer annular areas or between the outer annular areas. The stress relaxing portion (124) includes a plurality of curved portions including a first curved portion (128a) having the largest radius, and a second curved portion (128b) and a third curved portion (128c) which are formed respectively at both ends of the first curved portion (128a) such that a space lies on the outer side of each of the second and third curved portions (128b, 128c).
摘要翻译：燃料电池模块（12）包括燃料电池堆（24）和FC外围设备（38）。在燃料电池模块（12）中，至少沿着中心区域和一个外部环形区域之间或外部环形区域之间的边界设置用于缓和热应力的应力缓和部分（124）。应力缓和部（124）包括多个弯曲部，其包括具有最大半径的第一弯曲部（128a）和分别形成在第二弯曲部（128a）的两端的第二弯曲部（128b）和第三弯曲部（128c）所述第一弯曲部分（128a）使得空间位于所述第二和第三弯曲部分（128b，128c）中的每一个的外侧。

9. 发明申请

WO2015008807A1 CLAMP APPARATUS 审中-公开
标题翻译：夹钳装置
公开(公告)号：WO2015008807A1
公开(公告)日：2015-01-22
申请号：PCT/JP2014/068969
申请日：2014-07-10
申请人： SMC CORPORATION
发明人： FUKUI, Chiaki , TAKAHASHI, Kazuyoshi , SASAKI, Hideki , KOBAYASHI, Masaharu
IPC分类号： B25B5/00 , B25B5/06
CPC分类号： B25B5/064 , B25B5/003
摘要： A clamp apparatus (10) is equipped with two pairs of first and second clamp arms (14, 16), which are supported rotatably with respect to a body (12) and are disposed mutually in parallel. First and second cam members (56, 64) including respective cam surfaces (58, 66) are provided on ends of the first and second clamp arms (14, 16). The first cam members (56) are pressed by rollers (90) upon lowering of a block body (88a) under a driving action of a first cylinder (36) that makes up a drive unit (18). As a result, the first clamp arms (14) are rotated to assume a clamped state. On the other hand, the second cam members (64) are pressed by rollers (90) upon lowering of a block body (88b) under a driving action of a second cylinder (38) of the drive unit (18), whereby the second clamp arms (16) are rotated to assume a clamped state.
摘要翻译：夹具装置（10）装备有两对第一和第二夹臂（14,16），它们相对于主体（12）可旋转地支撑并且彼此相互平行设置。包括相应的凸轮表面（58,66）的第一和第二凸轮构件（56,64）设置在第一和第二夹紧臂（14,16）的端部上。在构成驱动单元（18）的第一气缸（36）的驱动作用下，第一凸轮构件（56）在块体（88a）下降时由辊（90）按压。结果，第一夹臂（14）旋转以呈现夹紧状态。另一方面，在驱动单元（18）的第二气缸（38）的驱动作用下，在块体（88b）下降时，第二凸轮构件（64）被辊（90）按压，由此第二凸轮构件夹臂（16）旋转以呈现夹紧状态。

10. 发明申请

WO2014171264A1 FUEL CELL MODULE 审中-公开
标题翻译：燃料电池模块
公开(公告)号：WO2014171264A1
公开(公告)日：2014-10-23
申请号：PCT/JP2014/057945
申请日：2014-03-14
申请人： HONDA MOTOR CO., LTD.
发明人： OGAWA, Tetsuya , YOSHIMINE, Yuki
IPC分类号： H01M8/06 , H01M8/04 , F28D7/00
CPC分类号： H01M8/0618 , B01J8/067 , B01J2208/00194 , B01J2208/00212 , B01J2208/00221 , B01J2208/0053 , B01J2208/00716 , C01B3/34 , C01B2203/0233 , C01B2203/066 , C01B2203/0811 , C01B2203/1258 , C01B2203/1288 , C01B2203/141 , F24D2200/19 , F24H1/403 , F24H2240/10 , F28D7/0066 , F28D7/1607 , F28D7/1676 , H01M8/04022 , H01M8/04067 , H01M8/0631 , H01M8/0662 , H01M8/24 , H01M2008/1293 , H01M2250/20 , Y02E60/50 , Y02E60/525 , Y02P20/124 , Y02T90/32
摘要： A fuel cell module (12) includes a first area (R1) where an exhaust gas combustor (52) and a start-up combustor (54) are provided, an annular second area (R2) around the first area (R1) and where a reformer (46) and a heat exchanger (50) are provided, and an annular third area (R3) around the second area (R2) and where an evaporator (48) is provided. Second circumscribed non-uniform-flow suppression plates (116a, 116b) are provided along the minimum circumscribed circles which contact outer surfaces of heat exchange pipes (74) of the heat exchanger (50).
摘要翻译：燃料电池模块（12）包括设置有排气燃烧器（52）和启动燃烧器（54）的第一区域（R1），围绕第一区域（R1）的环形第二区域（R2），并且其中设置有重整器（46）和热交换器（50），以及围绕第二区域（R2）的环形第三区域（R3），并且设置有蒸发器（48）。沿着与热交换器（50）的热交换管（74）的外表面接触的最小外接圆设置第二外接非均匀流动抑制板（116a，116b）。

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