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1. 发明授权

US12070992B2 Rolling tonneau cover 有权
公开(公告)号：US12070992B2
公开(公告)日：2024-08-27
申请号：US18144571
申请日：2023-05-08
申请人： Leer Group
发明人： Eugene A. Dylewski, II , Christopher David Mattison , John William Bevis, III
IPC分类号： B60J7/14 , B60J7/08 , B60R5/04
CPC分类号： B60J7/141 , B60J7/085 , B60R5/047
摘要： A tonneau cover assembly that selectively covers a truck bed of a truck is provided. The tonneau cover assembly includes a cover and a longitudinally extending rail located adjacent a sidewall of the truck bed. The longitudinally extending rail includes an attachment member. The attachment member extends longitudinally along with the rail and at least a portion of the attachment member is located over a portion of the bed. The cover includes a stiffener located adjacent the attachment member of the longitudinally extending rail.

2. 发明授权

US12070537B2 Membrane and device for treating restless leg syndrome 有权
公开(公告)号：US12070537B2
公开(公告)日：2024-08-27
申请号：US17668480
申请日：2022-02-10
申请人： GAMBRO LUNDIA AB
发明人： Angelito A. Bernardo , Angela Sofia Rivera Florez , Lars-Goran Nilsson , Rafael Mauricio Sanabria Arenas , Alfonso Bunch Barrera
IPC分类号： A61M1/16 , A61K31/197 , A61K31/381 , A61K31/404 , A61P25/00 , B01D61/24 , B01D63/02 , B01D69/02 , B01D69/08 , B01D71/68
CPC分类号： A61M1/16 , A61K31/197 , A61K31/381 , A61K31/404 , A61P25/00 , B01D61/243 , B01D63/02 , B01D69/02 , B01D69/084 , B01D71/68 , B01D2325/04 , B01D2325/20
摘要： The present disclosure relates to a hemodialysis membrane for the treatment of restless leg syndrome (RLS), especially in severe and very severe cases and/or in patients which suffer from kidney failure and already receive hemodialysis. The present disclosure therefore also relates to methods of treating restless leg syndrome. The treatment and method encompasses using a hemodialysis membrane which is characterized in that it comprises at least one hydrophobic polymer and at least one hydrophilic polymer and in that it has a MWRO of between 8.5 and 14.0 kD and a MWCO of between 55 kD and 130 kD.

3. 发明授权

US12067797B2 Product labeling review 有权
公开(公告)号：US12067797B2
公开(公告)日：2024-08-20
申请号：US17408181
申请日：2021-08-20
申请人： PEPSICO, INC.
发明人： Jingting Hui
IPC分类号： G06V30/10 , G06F16/35 , G06F16/38 , G06F40/12 , G06F40/183 , G06V30/413 , G06V30/414
CPC分类号： G06V30/414 , G06F16/35 , G06F16/381 , G06F40/12 , G06F40/183 , G06V30/413 , G06V30/10
摘要： A label processing engine receives, as inputs, raw data representative of a label and baseline data, detects a raw data object within the raw data, classifies the raw data object, and localizes the raw data object within the raw data, detects a baseline data object within the baseline data, classifies the baseline data object, and localizes the baseline data object within the baseline data. The engine recognizes corresponding text within the raw data object and the baseline data object and extracts the corresponding text within the raw data object and the baseline data object, reassembles the corresponding text of the raw data object and the baseline data object into respective lines of text, compares the respective lines of text with one another, and issues a notification based on the comparison.

4. 发明授权

US12065979B2 Distributed electric and hybrid fans for distortion tolerance of turbofan engines 有权
公开(公告)号：US12065979B2
公开(公告)日：2024-08-20
申请号：US18088974
申请日：2022-12-27
申请人： Rolls-Royce North American Technologies Inc. , Rolls-Royce Corporation
发明人： Robert W. Heeter , Daniel E. Molnar, Jr. , Kathryn A. Sontag , Michael G. Meyer
IPC分类号： F02C9/20 , F02C3/06 , F02K3/04 , B64D31/06
CPC分类号： F02C9/20 , F02C3/06 , F02K3/04 , B64D31/06 , F05D2220/32 , F05D2260/60
摘要： A gas turbine engine comprises a primary fan and an engine core. The primary fan is mounted for rotation about an axis of the gas turbine engine to provide thrust. The engine core is coupled to the primary fan and configured to drive the primary fan about the axis to cause the fan to push air to provide thrust for the gas turbine engine.

5. 发明授权

US12065965B1 Rotating detonation augmentors with adjustable throats for gas turbine engines 有权
公开(公告)号：US12065965B1
公开(公告)日：2024-08-20
申请号：US18234340
申请日：2023-08-15
申请人： Rolls-Royce North American Technologies Inc. , Rolls-Royce Corporation
发明人： Victor L. Oechsle , Kenneth M. Pesyna , Bryan H. Lerg , Michael C. Monzella , Zachary A. Rauch , Michael Moser
IPC分类号： F02K3/11 , F02C5/00 , F02K3/02 , F02K3/075 , F23R7/00
CPC分类号： F02C5/00 , F02K3/025 , F02K3/075 , F02K3/11 , F23R7/00
摘要： A gas turbine engine includes a bypass duct and a rotating detonation augmentor. The bypass duct is configured to conduct air through a flow path arranged around an engine core of the gas turbine engine to provide thrust for propelling the gas turbine engine. The rotating detonation augmentor is located in the bypass duct and configured to be selectively operated to detonate fuel and a portion of the air to increase the thrust for propelling the gas turbine engine.

6. 发明授权

US12064632B2 Method and device for feedback control of neural stimulation 有权
公开(公告)号：US12064632B2
公开(公告)日：2024-08-20
申请号：US17818193
申请日：2022-08-08
申请人： Saluda Medical Pty Ltd
发明人： Peter Scott Vallack Single , Dean Michael Karantonis
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36139 , A61N1/0551 , A61N1/36062 , A61N1/36071
摘要： A method of controlling a neural stimulus by use of feedback. The neural stimulus is applied to a neural pathway in order to give rise to an evoked action potential on the neural pathway. The stimulus is defined by at least one stimulus parameter. A neural compound action potential response evoked by the stimulus is measured. From the measured evoked response a feedback variable is derived. A feedback loop is completed by using the feedback variable to control the at least one stimulus parameter value. The feedback loop adaptively compensates for changes in a gain of the feedback loop caused by electrode movement relative to the neural pathway.

7. 发明授权

US12060921B2 Vertical cable railing assembly 有权
公开(公告)号：US12060921B2
公开(公告)日：2024-08-13
申请号：US18452143
申请日：2023-08-18
申请人： Digger Specialties, Inc.
发明人： Loren R. Graber , Wendell J. Miller
IPC分类号： F16G11/12 , E04F11/18
CPC分类号： F16G11/12 , E04F11/1817 , E04F11/1842 , E04F11/1859 , E04F2011/1819
摘要： A railing system is provided that illustratively includes a first rail and a second rail where the first rail is spaced-apart from the second rail. At least one cable that extends between the spaced-apart first and second rails. The at least one cable includes a stop sleeve disposed about the cable and positioned adjacent an end of the at least one cable. A cable tensioner having a body, a bore disposed through the body, and a stop surface is located adjacent an opening in the cable tensioner. An adapter that includes a body and a bore that extends into the body. The body of the adapter forms a surface located in contact with an underside surface of the top panel of the second rail between the first and second sidewalls of the second rail.

8. 发明授权

US12060585B2 Expression of novel cell tags 有权
公开(公告)号：US12060585B2
公开(公告)日：2024-08-13
申请号：US17302514
申请日：2021-05-05
申请人： PRECIGEN, INC.
发明人： Rutul Shah , Peter Emtage , Ramya Yarlagadda
IPC分类号： C12N9/12 , A61K35/17 , A61K39/00 , A61K39/395 , A61P35/00 , C07K14/54 , C07K14/705 , C07K14/71 , C07K14/725 , C07K16/28 , C07K16/32
CPC分类号： C12N9/12 , A61K35/17 , A61K39/3955 , A61P35/00 , C07K14/5443 , C07K14/70503 , C07K14/7051 , C07K14/70521 , C07K14/70578 , C07K14/70592 , C07K14/70596 , C07K14/71 , C07K16/2887 , C07K16/32 , C12Y207/10001 , A61K2039/505 , C07K2317/622 , C07K2317/732 , C07K2317/734 , C07K2319/00 , C07K2319/02 , C07K2319/03 , C07K2319/33
摘要： Disclosed herein are polynucleotides encoding cell tags for use in immunotherapeutic applications, and systems comprising polynucleotide cell tags for regulating the activity of a cell. The compositions, methods and systems described herein provide tools for regulating activity of genetically engineered cells in a subject.

9. 发明授权

US12059356B2 Orthopaedic knee prosthesis having controlled condylar curvature 有权
公开(公告)号：US12059356B2
公开(公告)日：2024-08-13
申请号：US17851373
申请日：2022-06-28
申请人： DEPUY IRELAND UNLIMITED COMPANY
发明人： Joseph G. Wyss , Christel M. Wagner , Dimitri Sokolov , Jordan S. Lee , John L. Williams , Said T. Gomaa , John M. Armacost
IPC分类号： A61F2/38 , A61F2/30
CPC分类号： A61F2/3886 , A61F2/3859 , A61F2/3868 , A61F2002/30116 , A61F2002/30332 , A61F2220/0033 , A61F2230/0006 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179
摘要： An orthopaedic knee prosthesis includes a tibial bearing and a femoral component configured to articulate with the tibial bearing. The femoral component includes a posterior cam configured to contact a spine of the tibial bearing and a condyle surface curved in the sagittal plane. The radius of curvature of the condyle surface decreases gradually between early-flexion and mid-flexion. Additionally, in some embodiments, the radius of curvature of the condyle surface may be increased during mid-flexion.

10. 发明授权

US12059051B2 System and method for designing and manufacturing a protective sports helmet 有权
公开(公告)号：US12059051B2
公开(公告)日：2024-08-13
申请号：US17878190
申请日：2022-08-01
申请人： Riddell, Inc.
发明人： Vittorio Bologna , Murphy Gillogly , Thad M. Ide
IPC分类号： A42C2/00 , A42B3/04 , G06T17/00 , B29L31/48
CPC分类号： A42C2/007 , A42B3/04 , G06T17/00 , B29L2031/4821
摘要： The invention relates to a protective sports helmet purposely designed for a selected group of helmet wearers from amongst a larger population of helmet wearers. A multi-step method for helmet design starts by collecting information from a population of players that may include information about the shape of a player's head and the impacts the player has sustained. This information is then processed to create player population information that is sorted to create categories. Advanced mathematical techniques are utilized to further sort these categories into player groups or data sets based on player attributes. Once the player groups are identified, another multi-step process is utilized to design optimized helmet prototype models for each player group. These optimized helmet prototype models are then further processed into complete helmet models by determining a structural design and chemical composition that is manufacturable and has mechanical properties that are substantially similar to the optimized helmet prototype model. Physical helmet prototypes are then created and tested using a unique helmet standard derived from information associated with each player group. Once the prototypes pass testing, the complete helmet models can be manufactured to create actual stock helmets or stock helmet components for future players whose characteristics and attributes place them within the selected player group.

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