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1. 发明申请

WO2012041965A1 PROCESS FOR PRODUCING DIALKYLPHOSPHOTRIESTERS OF NUCLEOSIDES BY ENZYMATIC TRANSESTERIFICATION AND DEPROTECTION THEREOF FOR PRODUCING NUCLEOSIDE MONOPHOSPHATES 审中-公开
标题翻译：用于生产核苷酸一磷酸酯的生物转化酶及其保护的生产核苷酸二磷酸酯的方法
公开(公告)号：WO2012041965A1
公开(公告)日：2012-04-05
申请号：PCT/EP2011/066988
申请日：2011-09-29
申请人： UNIVERSIDAD NACIONAL DE QUILMES , IRIBARREN, Claudia, Cristina , IRIBARREN, Adolfo, Marcelo , LEWKOWICZ, Elizabeth, Sandra , DETTORRE, Lucas, Andrés
发明人： IRIBARREN, Adolfo, Marcelo , LEWKOWICZ, Elizabeth, Sandra , DETTORRE, Lucas, Andrés
IPC分类号： C12P19/30 , C12N9/16
CPC分类号： C12P19/30 , C12N9/16 , C12Y301/04001 , C12Y301/08001
摘要： A process for producing nucleotide prodrugs, more particularly, the invention relates to a process for preparing dialkylphosphotnesters of nucleosides by enzymatic transesterification. The invention further describes deprotection processes for producing nucleoside monophosphates from nucleoside dialkylphosphotnesters.
摘要翻译：一种制备核苷酸前药的方法，更具体地说，本发明涉及一种通过酶促酯交换制备核苷二烷基磷光体的方法。本发明还描述了从核苷二烷基磷酸酯生产核苷单磷酸的脱保护方法。

2. 发明申请

WO2010097288A1 METHODS AND DEVICES FOR MANAGING MULTICAST TRAFFIC 审中-公开
标题翻译：用于管理多媒体业务的方法和设备
公开(公告)号：WO2010097288A1
公开(公告)日：2010-09-02
申请号：PCT/EP2010/051576
申请日：2010-02-09
申请人： MEDIA PATENTS, S. L. , FERNÁNDEZ GUTIÉRREZ, Álvaro
发明人： FERNÁNDEZ GUTIÉRREZ, Álvaro
IPC分类号： H04L12/56
CPC分类号： H04L45/00 , H04L12/185 , H04L45/16 , H04L45/54
摘要： A multicast router having one or more downstream network interfaces situated in a data network system between sources that send multicast packets to at least one multicast group address and one or more hosts that request data from the multicast group address and the sources. The multicast router receives ASM (Any Source Multicast) traffic requests and SSM (Source Specific Multicast) traffic requests from the one or more hosts using a host- router multicast routing protocol and stores for a downstream network interface and multicast group address at least one INCLUDE source record containing a non-empty source list derived by the SSM and the ASM traffic requests made by the one or more hosts and/or at least one EXCLUDE source record containing a non-empty Requested source list derived by the SSM and the ASM traffic requests made by the one or more hosts. In an alternative implementation a multicast router is provided that has one or more downstream network interfaces and is situated in a data network system between sources that send multicast packets to at least one multicast group address and multiple hosts that request data from the multicast group address and the sources. The multicast router stores for a each downstream network interface, each multicast group address and each host at least one INCLUDE source record and at least one EXCLUDE source record which are derived from ASM and SSM traffic requests made by the hosts using a host-router multicast routing protocol.
摘要翻译：具有位于数据网络系统中的一个或多个下游网络接口的组播路由器，所述数据网络系统在将多播分组发送到至少一个多播组地址的源和从多播组地址和源请求数据的一个或多个主机之间。多播路由器使用主机路由器组播路由协议接收来自一个或多个主机的ASM（任何源多播）流量请求和SSM（源特定多播）流量请求，并存储下游网络接口和多播组地址至少一个INCLUDE 源记录，其包含由SSM导出的非空源列表以及由一个或多个主机和/或至少一个包含由SSM和ASM流量导出的非空请求源列表的至少一个EXCLUDE源记录所做的ASM流请求一个或多个主机发出的请求。在替代实现中，提供了具有一个或多个下游网络接口并且位于数据网络系统中的数据路由器，所述数据网络系统在向多个组地址发送多播分组的源和从多播组地址请求数据的多个主机之间，以及来源。组播路由器存储每个下游网络接口，每个组播组地址和每个主机至少一个INCLUDE源记录和至少一个EXCUDE源记录，这些记录是从主机使用主机路由器多播从ASM和SSM流量请求中产生的路由协议

3. 发明申请

WO2010086341A1 SOLEPLATE AND IRON COMPRISING SUCH A SOLEPLATE 审中-公开
标题翻译：包括这样一个SOLEPLATE的SOLEPLATE和铁
公开(公告)号：WO2010086341A1
公开(公告)日：2010-08-05
申请号：PCT/EP2010/050953
申请日：2010-01-27
申请人： CELAYA, EMPARANZA Y GALDOS, INTERNACIONAL, S. A. , MADINA AGUIRRE, Aitor
发明人： MADINA AGUIRRE, Aitor
IPC分类号： D06F75/38 , H05B3/26
CPC分类号： D06F75/38
摘要： Soleplate for an iron characterized in that a substrate (2) of the soleplate (15) is made of a magnesium alloy, said alloy also comprising aluminium.
摘要翻译：用于熨斗的底板，其特征在于底板（15）的基板（2）由镁合金制成，所述合金还包括铝。

4. 发明申请

WO2010072611A1 METHODS FOR MANAGING MULTICAST TRAFFIC BETWEEN SOURCES SENDING DATA AND HOSTS REQUESTING DATA AND NETWORK EQUIPMENT USED TO IMPLEMENT THE METHODS 审中-公开
标题翻译：用于管理发送数据和主机数据之间的多媒体业务的方法和用于实现方法的网络设备
公开(公告)号：WO2010072611A1
公开(公告)日：2010-07-01
申请号：PCT/EP2009/067133
申请日：2009-12-15
申请人： MEDIA PATENTS, S. L. , FERNÁNDEZ GUTIÉRREZ, Alvaro
发明人： FERNÁNDEZ GUTIÉRREZ, Alvaro
IPC分类号： H04L12/18
CPC分类号： H04L12/185 , H04L45/02 , H04L45/16
摘要： A device, system and method for controlling the flow of multicast data packets from sources sending data to hosts requesting the data. In one implementation, a router (9) is situated in a data network between sources (12, 13) that send multicast data packets directed to a multicast group and hosts (2, 3) requesting to receive the multicast data packets. The router has one or more network interfaces in the direction of the hosts and stores for each network interface, each multicast group address and each host at least one data record arising from one or more data requests made by the hosts which includes multicast group and source information. The router stores executable instructions to receive messages originating from a host, update the status of the data sources for that host and implement actions.
摘要翻译：一种用于控制来自发送数据到源请求数据的主机的组播数据分组流的设备，系统和方法。在一个实现中，路由器（9）位于数据网络中，源（12,13）之间发送指向多播组的组播数据分组，并且主机（2,3）请求接收多播数据分组。路由器在主机方向上具有一个或多个网络接口，并为每个网络接口存储每个组播组地址，每个主机至少由一个或多个数据请求产生的数据记录，主机包括多播组和源信息。路由器存储可执行指令以接收源自主机的消息，更新该主机的数据源的状态并实施动作。

5. 发明申请

WO2010020606A1 DEVICE FOR USE IN SURGICAL TREATMENT OF FUNNEL CHEST AND METHOD OF TREATMENT 审中-公开
标题翻译：用于手术治疗的手术设备和治疗方法
公开(公告)号：WO2010020606A1
公开(公告)日：2010-02-25
申请号：PCT/EP2009/060605
申请日：2009-08-17
申请人： CORPORACIÓ SANITÀRIA PARC TAULÍ , BARDAJÍ PASCUAL, Carlos
发明人： BARDAJÍ PASCUAL, Carlos
IPC分类号： A61B17/80
CPC分类号： A61B17/8076 , A61B17/8685
摘要： A device (1) for use in the surgical treatment of a patient suffering from funnel chest characterised in that it comprises a plate adapted to be fitted underneath the skin of the patient, and further characterised in that, in use, said plate can be attached to the patient's sternum and the curvature, length and width of the plate being such that the plate extends on both sides of the sternum and on the outside of the patient's thorax and is supported by the ribs to hold up the sternum.
摘要翻译：一种用于手术治疗患有漏斗胸部的患者的装置（1），其特征在于，其包括适于安装在患者皮肤下面的板，其特征还在于，在使用中，所述板可以附接到患者的胸骨，并且板的曲率，长度和宽度使得板在胸骨的两侧和患者的胸部的外侧延伸并且由肋支撑以支撑胸骨。

6. 发明申请

WO2009150233A2 METHOD FOR SENDING DATA PACKETS IN A DATA NETWORK DURING HANDOVER OF A MOBILE NODE 审中-公开
标题翻译：移动移动节点切换期间数据网络中发送数据包的方法
公开(公告)号：WO2009150233A2
公开(公告)日：2009-12-17
申请号：PCT/EP2009/057309
申请日：2009-06-12
申请人： MEDIA PATENTS, S. L. , FERNÁNDEZ GUTIÉRREZ, Álvaro
发明人： FERNÁNDEZ GUTIÉRREZ, Álvaro
IPC分类号： H04L29/12 , H04W36/00
CPC分类号： H04W36/02 , H04L29/1232 , H04L29/12367 , H04L29/12933 , H04L61/2092 , H04L61/2514 , H04L61/6059 , H04L61/6068 , H04W8/26 , H04W36/0011 , H04W80/04
摘要： A method and equipment for transmitting data packets in a data network originating from a mobile node. In one embodiment a method involves the mobile node transmitting immediately after a handover from a first router to a second router data packets having a source address that includes a local level 3 source address in the OSI model.
摘要翻译：一种用于在源自移动节点的数据网络中发送数据分组的方法和设备。在一个实施例中，一种方法涉及移动节点在从第一路由器到第二路由器的切换之后立即发送具有包括OSI模型中的本地级3源地址的源地址的数据分组。

7. 发明申请

WO2009138433A1 INITIATION METHOD FOR ABNORMAL GLOW PLASMA DISCHARGE IN A LIQUID-PHASE MEDIUM AND APPARATUS FOR ITS IMPLEMENTATION 审中-公开
标题翻译：液相色谱法异步玻璃等离子体放电的启动方法及其实现装置
公开(公告)号：WO2009138433A1
公开(公告)日：2009-11-19
申请号：PCT/EP2009/055784
申请日：2009-05-13
申请人： RESEARCH AND INNOVATION INC. , BARLOCCI PENNATI, Anna , ZOLEZZI-GARRETON, Alfredo , ABRAMOV, Oleg , ABRAMOV, Vladimir
发明人： ZOLEZZI-GARRETON, Alfredo , ABRAMOV, Oleg , ABRAMOV, Vladimir
IPC分类号： H05H1/24
CPC分类号： H05H1/2475 , H05H2001/2481
摘要： A method and apparatus for initiating and maintaining an abnormal glow volumetric sonoplasma discharge (VSPD). With certain parameters of the electrical discharge and of the intensity of elastic vibrations, it is possible to initiate VSPD within a cavitating liquid medium. The mechanism for the initiation of VSPD is related to the breakdown of gas phase microchannels formed by growthcavitation bubbles. The method for continuous processing uses elastic vibrations in the frequency range 1 -100 kHz with enough intensity for the development of cavitation phenomena; these vibrations are introduced into the liquid phase working medium, and a source of direct, alternating, high frequency and ultrahigh frequency electric field in liquid provides the initiation and stable glow of VSPD. Resulting VSPD is characterized by volumetric glow in the frequency range of visible light and ultravioletradiation in the entire cavitational-electric field and has a rising volt-ampere characteristic curve.
摘要翻译：一种用于启动和维持异常发光体积超音速放电（VSPD）的方法和装置。通过放电的某些参数和弹性振动的强度，可以在气蚀液体介质内引发VSPD。启动VSPD的机理与由生长气泡形成的气相微通道的破坏有关。连续加工方法采用1〜100kHz频率范围内的弹性振动，具有足够的强度，用于气蚀现象的发展; 这些振动被引入到液相工作介质中，液体中的直接，交替，高频和超高频电场的源提供了VSPD的起始和稳定的发光。所得到的VSPD的特征在于在整个空穴电场中在可见光和紫外线的频率范围内的体积辉光，并且具有上升的伏安特性曲线。

8. 发明申请

WO2009103793A1 A SECURITY OPTICAL FIBER SENSOR 审中-公开
标题翻译：安全光纤传感器
公开(公告)号：WO2009103793A1
公开(公告)日：2009-08-27
申请号：PCT/EP2009/052049
申请日：2009-02-20
申请人： ESCUIN GARCÍA, Jorge
发明人： ESCUIN GARCÍA, Jorge
IPC分类号： G08B13/14
CPC分类号： G08B13/1445 , G08B13/1481 , G08B13/186
摘要： The invention relates to a security sensor (10) comprising a sensing device (21), a coming optical fiber element and a going optical fiber element, the sensing device (21) comprising a housing that receives a first end of the coming element and a first end of the going element. It is characterized in that the first end of the coming element and the first end of the going element in the housing are not aligned, and in that when a light beam enters the housing through the first end of the coming element, at least part of said light beam is reflected within the housing and exits through the first end of the going element.
摘要翻译：本发明涉及一种安全传感器（10），包括感测装置（21），即将来来的光纤元件和走向光纤元件，该感测装置（21）包括容纳即将到来的元件的第一端和元素的第一个结束。其特征在于，未来元件的第一端和壳体中的元件的第一端不对准，并且当光束通过未来元件的第一端进入壳体时，至少部分所述光束在壳体内被反射并且通过去除元件的第一端而离开。

9. 发明申请

WO2009092442A1 TREATMENT OF PORTAL HYPERTENSION AND RELATED CONDITIONS BY COMBINED INHIBITION OF THE VEGF AND PDGF SIGNALLING PATHWAYS 审中-公开
标题翻译：通过组合抑制VEGF和PDGF信号途径治疗门静脉高压和相关情况
公开(公告)号：WO2009092442A1
公开(公告)日：2009-07-30
申请号：PCT/EP2008/050770
申请日：2008-01-23
申请人： UNIVERSIDAD DE BARCELONA , INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER (IDIBAPS) , BOSCH GENOVER, Jaime , FERNÁNDEZ LOBATO, Mercedes
发明人： BOSCH GENOVER, Jaime , FERNÁNDEZ LOBATO, Mercedes
IPC分类号： A61K31/00 , A61K31/436 , A61K31/4412 , A61K31/506 , A61K45/06 , A61P1/16 , A61P9/12
CPC分类号： A61K31/436 , A61K31/44 , A61K31/506 , A61K45/06 , A61K2300/00
摘要： The present invention relates to the treatment and/or prevention of portal hypertension and manifestations related thereof, by the inhibition of both platelet-derived growth factorand vascular endothelial growth factor signalling pathways. Combinations of VEGF and PDGF signalling pathways inhibitors are disclosed for the treatment and/or prevention of portal hypertension, e.g. rapamycin and imatinib, sorafenib.
摘要翻译：本发明涉及通过抑制血小板衍生生长因子和血管内皮生长因子信号传导途径来治疗和/或预防门静脉高压及其相关表现。公开了VEGF和PDGF信号通路抑制剂的组合用于治疗和/或预防门静脉高压，例如，雷帕霉素和伊马替尼，索拉非尼。

10. 发明申请

WO2009087151A9 POLYMORPHIC FORMS OF MOXIFLOXACIN HYDROCHLORIDE AND PROCESSES FOR PREPARATION THEREOF 审中-公开
公开(公告)号：WO2009087151A9
公开(公告)日：2009-07-16
申请号：PCT/EP2009/050089
申请日：2009-01-07
申请人： CHEMO IBÉRICA, S.A. , VENTIMIGLIA, Gianpiero , MAGRONE, Domenico , CASTALDI, Graziano
发明人： VENTIMIGLIA, Gianpiero , MAGRONE, Domenico , CASTALDI, Graziano
IPC分类号： C07D471/04 , A61K31/437 , A61P31/04
摘要： Polymorphic hydrate crystalline forms of Moxifloxacin hydrochloride were found, referred to hereinafter as polymorphic Form α1 and Form α2. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms, to pharmaceutical compositions comprising them, as well as their use.

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