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    • 4. 发明申请
    • DRUG ELUTING SURGICAL SCREW
    • 药物治疗螺杆
    • WO2014028449A1
    • 2014-02-20
    • PCT/US2013/054671
    • 2013-08-13
    • DEPUY SYNTHES PRODUCTS, LLC.SYNTHES GMBH
    • ARMBRUSTER, DavidPANDEY, Anurag
    • A61B17/86
    • A61B17/864A61B17/86A61B17/8605A61B17/8615A61B17/866A61B17/8685A61B2017/00004A61B2017/00889A61B2017/00893
    • The present invention provides a drug eluting surgical screw and a method for manufacturing a drug eluting surgical screw. The drug eluting surgical screw may include a shaft having a threaded portion, a head having a drive recess disposed at a proximal end of the shaft, the drive recess having a reservoir region and a driver engagement region, and at least one or more drug eluting components disposed within the reservoir region of the drive recess in a manner that does not substantially impair a connection between a driver and the surgical screw when the driver is operably disposed within the driver engagement region, each of the at least one or more drug eluting components including a carrier matrix and a therapeutic agent, the therapeutic agent being at least 20 wt% of the drug eluting component prior to any implantation of the drug eluting surgical screw.
    • 本发明提供药物洗脱手术螺钉和药物洗脱手术螺钉的制造方法。 药物洗脱手术螺钉可以包括具有螺纹部分的轴,头部具有设置在轴的近端处的驱动凹部,驱动凹部具有储存区域和驱动器接合区域,以及至少一种或多种药物洗脱 当驱动器可操作地设置在驱动器接合区域内时,所述至少一个或多个药物洗脱组分中的每一个都不会基本上损害驱动器和外科用螺钉之间的连接的方式设置在驱动凹部的储存器区域内的部件 包括载体基质和治疗剂,所述治疗剂在药物洗脱手术螺钉的任何植入之前为药物洗脱组分的至少20重量%。
    • 7. 发明申请
    • SURGICAL DRILL BITS
    • 手术钻头
    • WO2013154686A1
    • 2013-10-17
    • PCT/US2013/027747
    • 2013-02-26
    • DEPUY SYNTHES PRODUCTS, LLC.
    • SCHOUTENS, Robert, J.
    • A61B17/16B23B51/02
    • A61B17/1615A61B17/1617
    • A surgical drill bit (10) can include a body portion (30) that defines a central axis (C) that extends along a first direction. The body portion can be separated along the first direction into a distal cutting segment (70), and a guiding segment (74). The body portion can include a helical flute (78) that winds about the central axis. The helical flute can define a first outer profile along the cutting segment and a second outer profile along the guiding segment, the first outer profile has a first leading edge (90) and a first bearing surface (98) and the second outer profile has a second leading edge (120) and a second bearing surface (128. The first leading edge can be configured to cut into bone and can be spaced from the central axis by a first length (LL1). The second leading edge can be spaced from the central axis by a second length (LL2) that is less than the first length.
    • 手术钻头(10)可以包括限定沿着第一方向延伸的中心轴线(C)的主体部分(30)。 主体部分可以沿着第一方向分离成远侧切割段(70)和引导段(74)。 主体部分可以包括围绕中心轴线卷绕的螺旋槽(78)。 螺旋槽可以沿着切割段限定第一外部轮廓,并且沿着引导段限定第二外部轮廓,第一外部轮廓具有第一前缘(90)和第一支撑表面(98),并且第二外部轮廓具有 第二前缘(120)和第二支承表面(128)。第一前缘可构造成切入骨头并且可以与中心轴线间隔第一长度(LL1),第二前缘可与 中心轴线小于第一长度的第二长度(LL2)。