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    • 7. 发明申请
    • A PHARMACEUTICAL COMPOSITION FOR USE IN TREATING OR PREVENTING EITHER ONE OR BOTH OF AN INFLAMMATORY DISEASE AND AN AUTOIMMUNE DISEASE
    • 用于治疗或预防任何一种或两种炎性疾病和自发性疾病的药物组合物
    • WO2014067959A1
    • 2014-05-08
    • PCT/EP2013/072631
    • 2013-10-29
    • SUPPREMOL GMBH
    • BUCKEL, PeterSONDERMANN, PeterTILLMANNS, SaschaBERGER, Ingrid
    • C07K14/735A61K38/17
    • A61K38/177C07K14/70535
    • The present invention relates to a pharmaceutical composition for use in treating or preventing either one or both of an inflammatory disease and an autoimmune disease, wherein the pharmaceutical composition comprises soluble Fcγ receptor (FcγR) as active ingredient; and wherein the pharmaceutical composition is designed for administering a first dose of a therapeutically effective amount of soluble FcγR, followed by a safety period of several weeks, followed by a subsequent treatment cycle of at least two further administrations, wherein said therapeutically effective amount is effective to treat or prevent said disease in said patient. Further the invention relates to a pharmaceutical composition in the form of a multiple-dosage-kit which contains sufficient amounts of administration doses of soluble FcγR for effectively treating or preventing inflammatory diseases and/or autoimmune diseases in a patient.
    • 本发明涉及用于治疗或预防炎性疾病和自身免疫性疾病中的一种或两种的药物组合物,其中所述药物组合物包含可溶性Fcγ受体(FcγR)作为活性成分; 并且其中所述药物组合物被设计用于施用第一剂量的治疗有效量的可溶性FcγR,随后是几周的安全期,随后是至少两次其它给药的随后治疗周期,其中所述治疗有效量是有效的 以治疗或预防所述患者中的所述疾病。 此外,本发明涉及多剂量试剂盒形式的药物组合物,其含有足够量的施用剂量的可溶性FcγR,用于有效治疗或预防患者的炎性疾病和/或自身免疫性疾病。