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1. 发明专利

TW200305601A 新穎的矽烷改質之羧酸取代胺及其鹽 NOVEL SILANE MODIFIED CARBOXYLIC ACID SUBSTITUTED AMINES AND SALTS THEREOF 审中-公开
简体标题：新颖的硅烷改质之羧酸取代胺及其盐 NOVEL SILANE MODIFIED CARBOXYLIC ACID SUBSTITUTED AMINES AND SALTS THEREOF
公开(公告)号：TW200305601A
公开(公告)日：2003-11-01
申请号：TW092105210
申请日：2003-03-11
申请人：合衆化學工業股份有限公司 UNITED CHEMICAL TECHNOLOGIES, INC.
发明人：溫妮金 WAYNE KING , 約翰 H 麥克米蘭 JOHN H. MACMILLAN , 麥克 J 泰勒查克 MICHAEL J. TELEPCHAK
IPC分类号： C08L
CPC分类号： C07F7/1836 , C07F7/184 , C07F7/1844
摘要：本發明係提供新穎化合物，其包含矽烷改質之羧酸取代胺及其鹽。本發明之化合物在固定相之狀態下提供多種乙二胺四乙酸及其鹽所需的性質。本發明也係關於提供一種用於合成根據本發明之化合物之方法。
简体摘要：本发明系提供新颖化合物，其包含硅烷改质之羧酸取代胺及其盐。本发明之化合物在固定相之状态下提供多种乙二胺四乙酸及其盐所需的性质。本发明也系关于提供一种用于合成根据本发明之化合物之方法。

2. 发明申请

WO2002102879A3 SUPPORTED ALDEHYDIC SILANES AND METHOD OF MANUFACTURE 审中-公开
公开(公告)号：WO2002102879A3
公开(公告)日：2002-12-27
申请号：PCT/US2002/010028
申请日：2002-03-27
申请人： UNITED CHEMICAL TECHNOLOGIES, INC.
发明人： COYNE, Ann , MACMILLAN, John, H. , TELEPCHAK, Michael, J.
IPC分类号： G01N33/552
摘要： A method for producing a derivatized aldehydic support matrix material includes activating surface hydroxyl groups on the support matrix material and reacting the actived hydroxyl groups with an aldehydic alkoxy sialne. The derivatized aldehydic support matrix material produced is useful for immobilizing bio-molecules in biological applications.

3. 发明申请

WO2003078442A1 NOVEL SILANE MODIFIED CARBOXYLIC ACID SUBSTITUTED AMINES AND SALTS THEREOF 审中-公开
标题翻译：新型硅烷改性羧酸取代的氨基酸及其盐
公开(公告)号：WO2003078442A1
公开(公告)日：2003-09-25
申请号：PCT/US2003/007141
申请日：2003-03-10
申请人： UNITED CHEMICAL TECHNOLOGIES, INC.
发明人： KING, Wayne , MACMILLAN, John, H. , TELEPCHAK, Michael, J.
IPC分类号： C07F7/10
CPC分类号： C07F7/1836 , C07F7/184 , C07F7/1844
摘要： Novel compounds comprising silane modified carboxylic acid substituted amines and salts thereof are provided. The compounds according to the invention provide many of the desirable properties of ethylenediamine tetraacetic acid and its salts in a stationary phase. A process for synthesis of the compounds according to the invention are also provided.
摘要翻译：提供了包含硅烷改性的羧酸取代的胺及其盐的新型化合物。根据本发明的化合物在固定相中提供了乙二胺四乙酸及其盐的许多所需性质。还提供了合成本发明化合物的方法。

4. 发明公开

EP1208106A1 METHOD FOR THE PREPARATION OF AMINOPROPYL OR AMINOALKYL FUNCTIONAL POLYALKYL OR ARYL SILOXANES 审中-公开
标题翻译：用于生产氨丙基或氨基官能聚烷基或芳基硅氧烷
公开(公告)号：EP1208106A1
公开(公告)日：2002-05-29
申请号：EP00961393.6
申请日：2000-08-29
申请人： United Chemical Technologies, Inc.
发明人： MARZINKE, Marla , MACMILLAN, John, H. , AUGUST, Thomas, F. , TELEPCHAK, Michael, J.
IPC分类号： C07F7/08 , C07F7/10
CPC分类号： C08G77/388
摘要： A new method for the preparation of aminopropyl terminated or internal functionalized polyalkyl or aryl siloxanes is described. The method involves readily available commercial starting materials and proceeds under mild conditions in high yield. Purification is facilitated over present commercial procedures and a wider variety of internal functionalized siloxanes may be prepared. The method involves hydrosilation of commercially available alkyl or aryl functional hydrosilicones with allyl amine or other alkenyl or arenyl amine in the presence of platinum(0)divinyltetramethylsiloxane or platinum(0)cyclovinyl complexes.

5. 发明公开

EP1292814A1 MICROCOLUMN FOR USE IN SAMPLE EXTRACTION 审中-公开
标题翻译：微孔用于样品提取
公开(公告)号：EP1292814A1
公开(公告)日：2003-03-19
申请号：EP01939784.3
申请日：2001-05-31
申请人： United Chemical Technologies, Inc.
发明人： AUGUST, Thomas, F. , TELEPCHAK, Michael, J.
IPC分类号： G01N1/00
CPC分类号： G01N1/405 , G01N30/6004
摘要： A housing (10) is described for use in preparing a sample for chemical analysis, the housing having a sample entrance (12), a sample exit (14), and a passageway (16) therebetween; the housing further comprising at least three ridges, the ridges integral with the housing, depending into the passageway, and defining a supporting profile for holding a sorbent retaining member.
摘要翻译：描述了用于制备用于化学分析的样本的外壳（10），外壳具有样本入口（12），样本出口（14）和其间的通道（16）; 所述壳体还包括至少三个隆起部，所述隆起部与所述壳体成一体，并依赖于所述通道并且限定用于保持吸附剂保持构件的支撑轮廓。

6. 发明公开

EP1082214A1 EXTRACTION MATERIAL AND METHOD FOR DETERMINATION OF GAMMA-HYDROXYBUTYRATE 审中-公开
标题翻译： EXTRA TION材料和方法测定的γ-羟
公开(公告)号：EP1082214A1
公开(公告)日：2001-03-14
申请号：EP00901380.6
申请日：2000-01-03
申请人： United Chemical Technologies, Inc.
发明人： KITCHEN, Chester, J. , AUGUST, Thomas, F. , OZANICH, William, L. , TELEPCHAK, Michael, J.
IPC分类号： B32B9/00
CPC分类号： B01J20/103 , B01J20/28004 , B01J20/283 , B01J20/286 , B01J20/3204 , B01J20/3257 , B01J20/3261 , B01J2220/54 , B01J2220/58 , B01J2220/62 , Y10T428/2995
摘要： A treated silica composition particularly useful for solid phase extraction in chemical analysis, the silica having both phenyl and propylsulfonic acid functional groups; a cartridge for extraction which comprises the treated silica; a column for extraction which comprises the treated silica; and a method for solid phase extraction which uses the silica composition. A method for analysis of gamma hydroxybutyric acid is also disclosed which uses the treated silica.

7. 发明授权

US07666686B2 Method for sample preparation by solid phase extraction 有权
标题翻译：固相萃取法制备样品
公开(公告)号：US07666686B2
公开(公告)日：2010-02-23
申请号：US11434270
申请日：2006-05-15
申请人： Donald L. Shelly, Jr. , Phillip Spraker , William L. Ozanich, Jr. , Michael J. Telepchak
发明人： Donald L. Shelly, Jr. , Phillip Spraker , William L. Ozanich, Jr. , Michael J. Telepchak
IPC分类号： G01N1/18
CPC分类号： G01N1/405 , B01D2253/106 , B01D2257/80 , B01J20/103 , B01J20/20 , B01J20/28052 , B01J20/3242 , Y10T436/25375 , Y10T436/255 , Y10T436/25875
摘要： An method for sample preparation using solid phase extraction. Using an apparatus comprising a SPE cartridge and a sorbent-containing gas filter which contains a sorbent and is detachably connected to the SPE cartridge the gas used to dry the SPE cartridge is purified by passage through the gas filter, thereby preventing contamination of the SPE sorbent by airborne contaminants.
摘要翻译：使用固相萃取的样品制备方法。使用包含SPE盒和含吸附剂的气体过滤器的装置，其包含吸附剂并且可拆卸地连接到SPE筒，用于干燥SPE筒的气体通过气体过滤器被净化，从而防止SPE吸附剂的污染由空气污染物。

8. 发明申请

US20030032012A1 Supported aldehydic silanes and method of manufacture 有权
标题翻译：支持醛硅烷和制造方法
公开(公告)号：US20030032012A1
公开(公告)日：2003-02-13
申请号：US09847212
申请日：2001-05-02
申请人： United Chemical Technologies, Inc.
发明人： Ann N. Coyne , John H. MacMillan , Michael J. Telepchak
IPC分类号： C12Q001/68 , C12M001/34 , B05D003/00 , G01N033/543
CPC分类号： C12N11/06 , C12N11/14
摘要： A method for producing a derivatized aldehydic support matrix material includes activating surface hydroxyl groups on the support matrix material and reacting the activated hydroxyl groups with an aldehydic alkoxy silane. The derivatized aldehydic support matrix material produced is useful for immobilizing bio-molecules in biological applications.
摘要翻译：制备衍生的醛类载体基质材料的方法包括活化载体基质材料上的表面羟基并使活化的羟基与醛烷氧基硅烷反应。所生成的衍生的醛基载体基质材料可用于在生物应用中固定生物分子。

9. 发明授权

US6156431A Extraction material comprising treated silica and method for determination of gamma-hydroxybutyrate 有权
标题翻译：包含处理过的二氧化硅的提取材料和γ-羟基丁酸酯的测定方法
公开(公告)号：US6156431A
公开(公告)日：2000-12-05
申请号：US224691
申请日：1999-01-04
申请人： Chester J. Kitchen , Thomas F. August , William L. Ozanich , Michael J. Telepchak
发明人： Chester J. Kitchen , Thomas F. August , William L. Ozanich , Michael J. Telepchak
IPC分类号： B01J20/10 , B01J20/32 , B32B5/16 , B01D24/00 , B01D39/06
CPC分类号： B01J20/103 , B01J20/28004 , B01J20/283 , B01J20/286 , B01J20/3204 , B01J20/3257 , B01J20/3261 , B01J2220/54 , B01J2220/58 , B01J2220/62 , Y10T428/2995
摘要： A treated silica composition particularly useful for solid phase extraction in chemical analysis, the silica having both phenyl and propylsulfonic acid functional groups; a cartridge for extraction which comprises the treated silica; a column for extraction which comprises the treated silica; and a method for solid phase extraction which uses the silica composition. A method for analysis of gamma hydroxybutyric acid is also disclosed which uses the treated silica.
摘要翻译：在化学分析中特别可用于固相萃取的经处理的二氧化硅组合物，具有苯基和丙磺酸官能团的二氧化硅; 用于提取的筒，其包含处理过的二氧化硅; 用于提取的柱，其包含处理过的二氧化硅; 以及使用二氧化硅组合物的固相萃取方法。还公开了用于分析γ-羟基丁酸的方法，其使用经处理的二氧化硅。

10. 发明授权

US07438862B2 Apparatus for simultaneous processing of multiple samples 有权
标题翻译：用于同时处理多个样品的装置
公开(公告)号：US07438862B2
公开(公告)日：2008-10-21
申请号：US10222192
申请日：2002-08-16
申请人： Ann N. Coyne , Michael J. Telepchak , Philip Spraker , Jay Hardee , John A. D'Asaro
发明人： Ann N. Coyne , Michael J. Telepchak , Philip Spraker , Jay Hardee , John A. D'Asaro
IPC分类号： B01L3/00
CPC分类号： B01L3/5025 , B01J2219/00274 , B01L3/50255 , B01L2200/141 , B01L2400/049
摘要： An apparatus is provided for simultaneous processing of multiple fluid samples. The apparatus comprises a multiple well plate for holding a plurality of sample reservoirs for simultaneous processing of multiple samples. The wells are configured in the plate in staggered rows. The well plate is dimensioned to be compatible with a vacuum manifold or positive pressure system either as a stand-alone unit or in conjunction with a separate fluid handling system. The apparatus may further comprise a sample collection plate having the same number of wells as the multiple well plate. The wells in the samples collection plate are arranged in the same staggered configuration as the wells in the well plate and are sized for holding sample collection vials. When the well plate and sample collection plate are assembled in a manifold, the vials in the sample collection plated are aligned directly beneath the sample exits of corresponding sample reservoirs in the well plate.
摘要翻译：提供了用于同时处理多个流体样品的装置。该装置包括用于保持多个样品储存器以用于多个样品的同时处理的多孔板。井在板中以交错排列配置。孔板的尺寸设计为与真空歧管或正压系统兼容，作为独立单元或与单独的流体处理系统结合。该装置还可以包括具有与多孔板相同数量的孔的样品收集板。样品收集板中的孔以与孔板中的孔相同的交错构型布置，并且尺寸适于保持样品采集瓶。当孔板和样品收集板组装在歧管中时，电镀样品中的小瓶直接对准孔板中相应样品储存器的样品出口的正下方。

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