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2. 发明专利

JP2012533869A Multiferroic nanoscale thin film material, magneto-electric coupling in its simple synthesis methods and room temperature 有权
公开(公告)号：JP2012533869A
公开(公告)日：2012-12-27
申请号：JP2012511942
申请日：2010-05-17
申请人：ノースロップグラマンシステムズコーポレイションNorthrop Grumman Systems Corporation , ザリサーチファンデーションオブザシティユニバーシティオブニューヨークThe Research Foundation Of The City University Of New York
发明人：ピリッチ、ロナルド , ヤン、ナン−ロー , スー、カイ , チュー、イー−ウェイ
IPC分类号： H01L29/82 , H01L21/8246 , H01L27/105
CPC分类号： C04B35/26 , B82Y40/00 , C04B35/6264 , C04B2235/3232 , C04B2235/3239 , C04B2235/3244 , C04B2235/3251 , C04B2235/3258 , C04B2235/327 , C04B2235/3275 , C04B2235/3279 , C04B2235/3289 , C04B2235/3298 , C04B2235/443 , C04B2235/768 , C23C18/1216 , H01L43/12
摘要：マルチフェロイック薄膜材料の製造方法。その方法は、マルチフェロイック前駆体溶液を提供する工程、その前駆体溶液をスピンキャスティングしてスピンキャスト膜を製造する工程、およびそのスピンキャスト膜を加熱する工程を有する。前駆体溶液は、ビスマスフェライト膜を製造するために、エチレングリコール中にＢｉ（ＮＯ３）３ｏ５Ｈ２ＯおよびＦｅ（ＮＯ３）３ｏ９Ｈ２Ｏを含有していてもよい。さらに、薄膜は、情報保存のための記憶デバイスを含む様々な技術分野において利用されうる。

3. 发明申请

WO2020234806A1 PEPTIDE IONOGEL COMPOSITION, METHODS AND USES THEREOF 审中-公开
公开(公告)号：WO2020234806A1
公开(公告)日：2020-11-26
申请号：PCT/IB2020/054794
申请日：2020-05-20
申请人： UNIVERSIDADE NOVA DE LISBOA , NOVA.ID.FCT - ASSOCIAÇÃO PARA A INOVAÇÃO E DESENVOLVIMENTO DA FCT , THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
发明人： AFONSO ROQUE, Ana Cecília , MARQUES ESTEVES, Carina Alexandra , VINCENT ULIJN, Rein
IPC分类号： H01B1/12
摘要： The present disclosure relates to an ionogel composition comprising at least one ionic liquid and at least one unprotected tripeptide as a gelator. Discs, films, fibers, spheres, cubes, meshes, channels or patterned structures comprising the ionogel composition are also encompassed. The present disclosure also relates to an article comprising the ionogel composition, the use of the ionogel composition and a method to prepare said ionogel composition.

4. 发明申请

WO2014124208A1 NSAIDs DERIVATIVES AND USES THEREOF 审中-公开
标题翻译： NSAIDs衍生物及其用途
公开(公告)号：WO2014124208A1
公开(公告)日：2014-08-14
申请号：PCT/US2014/015222
申请日：2014-02-07
申请人： THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
发明人： KASHFI, Khosrow , CHATTOPADHYAY, Mitali , KODELA, Ravinder
IPC分类号： A61K31/661
CPC分类号： C07D339/04 , C07F9/09 , C07F9/091 , C07F9/655345 , C07F9/65742
摘要： The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof. Non-steroidal anti-inflammatory drugs (NSAIDs) are prototypical agents for treatment of inflammatory conditions. NSAIDs may also have utility as therapeutic agents against many forms of cancers. However, long-term use of NSAIDs may lead to serious side effects affecting the gastrointestinal and renal systems.
摘要翻译：本发明公开了衍生自NSAIDs的新化合物及其药学上可接受的盐。本发明的其它方面涉及NSAID衍生物在治疗炎性疾病中的应用及其药物组合物。非甾体抗炎药（NSAIDs）是用于治疗炎性疾病的原型药物。 NSAID也可用作治疗剂以抵抗许多形式的癌症。然而，长期使用NSAID可能会导致影响胃肠和肾脏系统的严重副作用。

5. 发明申请

WO2013119552A2 CELLS AND METHODS FOR PRODUCING LUTEIN 审中-公开
标题翻译：用于生产罗廷辛的细胞和方法
公开(公告)号：WO2013119552A2
公开(公告)日：2013-08-15
申请号：PCT/US2013/024746
申请日：2013-02-05
申请人： THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
发明人： WURTZEL, Eleanore, T. , QUINLAN, Rena
IPC分类号： C12P23/00
CPC分类号： C12P23/00 , A23L33/135 , A23L33/145 , C07C403/24 , C12N9/001 , C12N9/0073 , C12N9/0083 , C12N9/1085 , C12N9/90 , C12Y103/05006 , C12Y114/13129 , C12Y114/99045 , C12Y205/01029 , C12Y205/01032 , C12Y505/01018 , C12Y505/01019
摘要： Provided herein are recombinant cells (e.g., recombinant bacteria or plant, insect, mammalian, and yeast cells) containing a nucleic acid encoding a CYP97A protein or a nucleic acid encoding a CYP97B protein; a nucleic acid encoding a CYP97C protein; a nucleic acid encoding a geranylgeranyl pyrophosphate synthase protein; a nucleic acid encoding a phytoene synthase protein; a nucleic acid encoding a phytoene desaturase protein; a nucleic acid encoding a lycopene β-cyclase protein; and a nucleic acid encoding a lycopene ε-cyclase protein. Also provided are methods of producing lutein that include culturing these recombinant cells (e.g., recombinant bacteria and yeast cells), and methods of generating these recombinant cells (e.g., recombinant bacteria and yeast cells). Also provided is lutein produced by these methods, and pharmaceutical compositions, food supplements, food products, and cosmetic compositions that contain lutein produced by these methods.
摘要翻译：本文提供了含有编码CYP97A蛋白的核酸或编码CYP97B蛋白的核酸的重组细胞（例如重组细菌或植物，昆虫，哺乳动物和酵母细胞）编码CYP97C蛋白质的核酸; 编码香叶基香叶基焦磷酸合酶蛋白的核酸; 编码芸苔属合酶蛋白的核酸; 编码八氢番茄红素去饱和酶蛋白的核酸; 编码番茄红素β-环蛋白的核酸; 和编码番茄红素ε-环化酶蛋白质的核酸。还提供了生产包括培养这些重组细胞（例如重组细菌和酵母细胞）的叶黄素的方法以及产生这些重组细胞（例如重组细菌和酵母细胞）的方法。还提供了通过这些方法生产的叶黄素，以及含有通过这些方法生产的叶黄素的药物组合物，食品添加剂，食品和化妆品组合物。

6. 发明申请

WO2012138988A2 ORGANOMETALLIC ANTI-CANCER COMPLEXES 审中-公开
标题翻译： ORGANOMETALLIC抗癌复合物
公开(公告)号：WO2012138988A2
公开(公告)日：2012-10-11
申请号：PCT/US2012/032507
申请日：2012-04-06
申请人： THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK , REDDY, Varattur Dayal
发明人： REDDY, Varattur Dayal
CPC分类号： C07F15/0046 , A61K31/555 , C07F19/00
摘要： An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.
摘要翻译：要求具有含有两个麦芽酚配体的有机金属三钌的抗癌钌络合物。

7. 发明申请

WO2010033726A3 DRUG DELIVERY COMPOSITION COMPRISING A SELF-ASSEMBLED GELATOR 审中-公开
公开(公告)号：WO2010033726A3
公开(公告)日：2010-03-25
申请号：PCT/US2009/057349
申请日：2009-09-17
申请人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , THE CITY UNIVERSITY OF NEW YORK REPRESENTED BY THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK , KARP, Jeffrey M. , VEMULA, Praveen, Kumar , JOHN, George , CRUIKSHANK, Greg
发明人： KARP, Jeffrey M. , VEMULA, Praveen, Kumar , JOHN, George , CRUIKSHANK, Greg
IPC分类号： A61K9/06 , A61K31/167 , A61P23/02 , A61P29/00 , A61K31/405 , A61K31/22 , A61K31/7034
摘要： This invention discloses drug-delivery compositions, methods of making prodrugs, and methods of drug delivery using a self-assembled gelator. The backbone of the gelator can contain a drug or prodrug, such as acetaminophen or salicin. Additional drugs or agents can be encapsulated in the gelator. Enzymatic or hydrolytic cleavage can be used to release the drugs.

8. 发明申请

WO2007069816A1 METHOD OF DETECTING AND SOLVING NETWORK ID CONFLICT 审中-公开
标题翻译：检测和解决网络ID冲突的方法
公开(公告)号：WO2007069816A1
公开(公告)日：2007-06-21
申请号：PCT/KR2006/003607
申请日：2006-09-11
申请人： SAMSUNG ELECTRONICS CO., LTD. , THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
发明人： LEE, Myung-jong , LIU, Yong
IPC分类号： H04L12/413
CPC分类号： H04W8/26 , H04L29/12264 , H04L61/2046 , H04W48/14 , H04W84/18
摘要： A method of detecting and solving a network ID conflict is provided. The method of detecting and solving a network ID conflict includes generating and transmitting a personal area network identifier (PAN ID) report command frame that includes an extended PAN ID, and receiving a PAN ID update command frame in response to the transmitted PAN ID report command frame. According to the method, the PAN ID report command and the PAN ID update command are generated and provided by providing an extended PAN ID (EPID), and thus a network ID conflict can be detected and a new PAN ID is provided to solve the network ID conflict.
摘要翻译：提供了一种检测和解决网络ID冲突的方法。检测和解决网络ID冲突的方法包括生成和发送包括扩展PAN ID的个人区域网络标识符（PAN ID）报告命令帧，以及响应于所发送的PAN ID报告命令接收PAN ID更新命令帧帧。根据该方法，通过提供扩展PAN ID（EPID）来生成和提供PAN ID报告命令和PAN ID更新命令，从而可以检测到网络ID冲突，并提供新的PAN ID以解决网络 ID冲突。

9. 发明申请

WO2005053619A2 CLOZAPINE AND COCAINE EFFECTS ON DOPAMINE AND SEROTONIN RELEASE IN NUCLEUS ACCUMBENS DURING PSYCHOSTIMULANT BEHAVIOR AND WITHDRAWAL 审中-公开
标题翻译：在精神分裂症行为和退缩期间，多巴胺和卡马林对多巴胺和丝氨酸蛋白酶释放的影响
公开(公告)号：WO2005053619A2
公开(公告)日：2005-06-16
申请号：PCT/US2004/040756
申请日：2004-12-06
申请人： THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK , BRODERICK, Patricia, A.
发明人： BRODERICK, Patricia, A.
IPC分类号： A61K
CPC分类号： A61K31/5513 , A61K31/4515 , A61K31/454 , A61K31/519 , A61K31/5415 , A61K31/551
摘要： The present invention provides methods of treating cocaine-induced pyschosis by administering an atypical antipsychotic compound in an amount sufficient to increase serotonin concentration in the nucleus accumbens of a mammal. According to the invention, atypical antipsychotic compounds include, without limitation, clozapine, risperidone, olanzepine, quetiapine, ziprasidone, sertindole, ketanserin, aripiprazole, and haloperidol, flupenthixol, thiroridazine, loxapine, fluspirilense, and sulpliride. The invention further provides methods for microvoltammetric imaging of changes in neurotransmitter concentrations in vivo and in real time comprising contacting the cell, cells, tissue, tissues, or organ of interest with a BRODERICK PROBE® sensor, applying a potential to said BRODERICK PROBE® sensor, and monitoring a temporally and spacially resolved recording using neuromolecular imaging (NMI) and electrochemical circuits such as, for example, voltammetry. In one embodiment of the invention, neuromolecular imaging may be performed before, during or after cocaine administration and/or cocaine-induced psychosis.
摘要翻译：本发明提供了通过施用足以增加哺乳动物伏隔核血清素浓度的量的非典型抗精神病化合物来治疗可卡因诱发的麻痹症的方法。根据本发明，非典型抗精神病药化合物包括但不限于氯氮平，利培酮，奥氮平，喹硫平，齐拉西酮，sertindole，ketanserin，阿立哌唑和氟哌啶醇，氟哌噻吨，噻瑞达嗪，洛沙平，氟哌利嗪和舒利替尼。本发明进一步提供用于在体内和实时的微量伏安成像神经递质浓度变化的方法，包括将感兴趣的细胞，细胞，组织，组织或器官与BRODERICK探针传感器接触，将潜力施加到所述BRODERICK PROBE （R）传感器，以及使用神经分子成像（NMI）和诸如例如伏安法的电化学电路监测时间和空间分辨的记录。在本发明的一个实施方案中，可以在可卡因给药和/或可卡因诱导的精神病之前，期间或之后进行神经分子成像。

10. 发明申请

WO2023034450A1 REAGENTS FOR SITE-SPECIFIC LABELING OF PROTEINS WITH RADIOHALOGENS, AND METHODS OF MAKING AND USING THE SAME 审中-公开
公开(公告)号：WO2023034450A1
公开(公告)日：2023-03-09
申请号：PCT/US2022/042257
申请日：2022-08-31
申请人： DUKE UNIVERSITY , THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
发明人： ZALUTSKY, Michael , FENG, Yutian , VAIDYANATHAN, Ganesan , ZEGLIS, Brian , SARRETT, Samantha
IPC分类号： A61K47/68 , C07D271/113 , A61K51/04 , A61K51/10
摘要： The present disclosure provides, in part, methods for site-specific labeling of proteins/peptides with radiohalogens and compositions resulting from said methods.

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