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1. 发明授权

US6156299A Topical compositions and methods for treating pseudofolliculitis barbae and ingrown hair 失效
标题翻译：用于治疗假性果皮炎和内向毛的局部组合物和方法
公开(公告)号：US6156299A
公开(公告)日：2000-12-05
申请号：US390605
申请日：1999-09-03
申请人： Steven E. Rosen , Robert Lee Brown
发明人： Steven E. Rosen , Robert Lee Brown
IPC分类号： A61K8/34 , A61K8/36 , A61K8/368 , A61K8/37 , A61K31/60 , A61Q9/02 , A61Q15/00 , A61K7/15
CPC分类号： A61Q15/00 , A61K8/342 , A61K8/345 , A61K8/361 , A61K8/368 , A61K8/37
摘要： Topical compositions and methods are disclosed for the treatment of pseudofolliculitis barbae and ingrown hair. The compositions comprise acetylsalicylic acid, propylene glycol, glycerine, and isopropyl alcohol. The method involves the step of applying the composition to the beard areas of the face after shaving. The acetylsalicylic acid is dissolved in a solvent mixture comprising propylene glycol, glycerine, and isopropyl alcohol. The acetylsalicylic acid is present in the range of between about 5 percent by weight per unit volume of the solvent mixture up to saturation of the solvent mixture. The solvent mixture comprises propylene glycol in the range of about 5 to 15 percent by volume, glycerine in the range of about 1 to 10 percent by volume, and the balance of the volume made up with isopropyl alcohol alone or a solution comprising at least 50 percent by volume of isopropyl alcohol. The isopropyl alcohol can be in a solution with water, methanol, or ethanol, provided that the polarity of the resulting solution is not so high that the acetylsalicylic acid would readily precipitate from the solution at ordinary room temperature ranges.
摘要翻译：公开了局部组合物和方法用于治疗假性果皮炎和内向毛发。组合物包含乙酰水杨酸，丙二醇，甘油和异丙醇。该方法包括在剃须后将组合物施用于面部的胡须区域的步骤。将乙酰水杨酸溶解在包含丙二醇，甘油和异丙醇的溶剂混合物中。乙酰水杨酸的存在量为每单位体积溶剂混合物的约5重量％，直至溶剂混合物饱和。溶剂混合物包含约5至15体积％的丙二醇，约1至10体积％的甘油，以及单独的异丙醇或其至少50重量％的溶液的体积余量异丙醇的体积百分数。异丙醇可以在与水，甲醇或乙醇的溶液中，只要所得溶液的极性不会高到乙酰水杨酸容易在常温常压下从溶液中沉淀出来。

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