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    • 1. 发明授权
    • Method and apparatus for uninterrupted delivery of radiographic dye
    • 射线染料不间断传送的方法和装置
    • US5533978A
    • 1996-07-09
    • US336252
    • 1994-11-07
    • Paul S. Teirstein
    • Paul S. Teirstein
    • A61B6/00A61M5/00A61M5/14A61M5/36A61M5/40A61M5/178
    • A61M5/007A61M5/1412A61M5/40A61M5/365
    • A method and apparatus for injecting radiographic dye during angiography are provided. A deformable holding chamber is interposed between a contrast dye bottle and a syringe manifold. A one-way valve and an integral disconnect/flow-stop are connected between the bottle and the holding chamber. A vent is provided in the holding chamber, with a second one-way valve. Squeezing and releasing the deformable chamber fills the chamber from the bottle. The holding chamber contains a floating baffle which acts as a shut off valve by plugging the chamber outlet if the chamber becomes empty. The syringe is used to withdraw dye from the holding chamber. If dye remains in the bottle after performance of the procedure, the disconnect/flow-stop fitting can be disconnected, and the dye can be saved.
    • 提供了用于在血管造影术期间注射放射线染料的方法和装置。 可变形的保持室插入造影剂瓶和注射器歧管之间。 瓶和保持室之间连接有单向阀和一体式断路器/止回阀。 通气口设置在保持室中,具有第二单向阀。 压缩和释放可变形室将瓶子从瓶中填充。 保持室包含浮动挡板,如果腔室变空,则该浮动挡板用作切断阀。 注射器用于从保持室中抽出染料。 如果在执行程序后染料残留在瓶子中,则断开/止流配件可以断开,并且可以保存染料。
    • 8. 发明授权
    • Irradiation catheter with expandable source
    • 带可扩张源的照射导管
    • US6050930A
    • 2000-04-18
    • US88840
    • 1998-06-02
    • Paul S. Teirstein
    • Paul S. Teirstein
    • A61M36/04A61N5/10A61N5/00
    • A61N5/1002A61N2005/1004
    • A radiation delivery system having an expandable radiation source made of a pliable material. The source body is made of a material such as a foam or sponge, or a fibrous material such as the soft bristles of a pipe cleaner. The spongy or fibrous material is made radioactive by the implantation of a radioactive isotope. The radioactive isotope can be located throughout the pliable source material, or concentrated in a desired region, such as the surface or near-surface region. This compressible radioactive source material, when constrained by a constraining housing or a catheter, has a very low profile. However, when the constraining housing or catheter is withdrawn, the expandable source material expands and fills the surrounding space, such as a blood vessel lumen. In this way, the radioactivity, impregnated in the expandable source material, is brought into direct contact with the vessel wall.
    • 具有由柔韧材料制成的可扩展辐射源的辐射传播系统。 源体由诸如泡沫或海绵的材料或诸如管道清洁器的软毛的纤维材料制成。 海绵状或纤维状材料通过植入放射性同位素而放射性。 放射性同位素可以位于整个柔性源材料中,或者集中在所需区域,例如表面或近表面区域。 这种可压缩放射源材料在被约束壳体或导管约束时具有非常低的轮廓。 然而,当约束壳体或导管被抽出时,可膨胀源材料膨胀并填充周围空间,例如血管内腔。 以这种方式,浸渍在可膨胀源材料中的放射性与容器壁直接接触。
    • 9. 发明授权
    • Method and apparatus for uninterrupted delivery of radiographic dye
    • 射线染料不间断传送的方法和装置
    • US5911708A
    • 1999-06-15
    • US57378
    • 1998-04-08
    • Paul S. Teirstein
    • Paul S. Teirstein
    • A61B6/00A61M5/00A61M5/14A61M5/36A61M5/40A61M5/178
    • A61M5/007A61M5/1412A61M5/40A61M5/365
    • A method and apparatus for injecting radiographic dye during angiography. A deformable holding chamber is interposed between a contrast dye bottle and a syringe manifold. A one-way valve and an integral disconnect/flow-stop are connected between the bottle and the holding chamber. A vent is provided in the holding chamber, which can include a second one-way valve. Squeezing and releasing the deformable chamber fills the chamber from the bottle. The holding chamber contains a floating baffle which acts as a shut off valve by plugging the chamber outlet if the chamber becomes empty. The syringe is used to withdraw dye from the holding chamber. If dye remains in the bottle after performance of the procedure, the disconnect/flow-stop fitting can be disconnected, and the dye can be saved.
    • 用于在血管造影术期间注射放射性染料的方法和装置。 可变形的保持室插入造影剂瓶和注射器歧管之间。 瓶和保持室之间连接有单向阀和一体式断路器/止回阀。 在保持室中设置有可以包括第二单向阀的排气口。 压缩和释放可变形室将瓶子从瓶中填充。 保持室包含浮动挡板,如果腔室变空,则该浮动挡板用作切断阀。 注射器用于从保持室中抽出染料。 如果在执行程序后染料残留在瓶子中,则断开/止流配件可以断开,并且可以保存染料。
    • 10. 发明授权
    • Irradiation catheter and method of use
    • 照射导管及使用方法
    • US5891091A
    • 1999-04-06
    • US643788
    • 1996-05-06
    • Paul S. Teirstein
    • Paul S. Teirstein
    • A61B17/00A61M25/00A61M25/10A61M36/04A61N5/10A61M29/00
    • A61N5/1002A61M25/1002A61M2025/0183A61M2025/1047A61M25/0023A61M25/0029A61M25/0032A61N2005/1003
    • A catheter for use with a radioactive source within the catheter to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter has a guidewire channel formed near its distal end to facilitate use of the catheter as a rapid exchange catheter, allowing insertion of the catheter over a guidewire also used in performance of an angioplasty procedure. The catheter can also have a guidewire channel formed near its proximal end to provide an O-ring sealing surface and to facilitate free guidewire movement. The catheter also has a closed end to retain the radioactive source within the catheter. The catheter can also be provided with a centering balloon or a set of centering wire loops to center the radioactive source radially within the blood vessel.
    • 导管,用于与导管内的放射源一起照射血管选定区域与血管成形术程序相结合,以防止血管区域的再狭窄。 导管具有在其远端附近形成的导丝通道,以便于将导管用作快速交换导管,允许将导管插入也用于执行血管成形术程序的导丝上。 导管还可以具有在其近端附近形成的导丝通道,以提供O形环密封表面并且促进自由导丝运动。 导管还具有封闭端以将放射源保持在导管内。 导管还可以设置有定心球或一组定心线环,以将放射源径向放置在血管内。