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1. 发明申请

WO2012068273A1 DEVICES AND METHODS FOR FORMING A FISTULA 审中-公开
标题翻译：用于形成FISTULA的装置和方法
公开(公告)号：WO2012068273A1
公开(公告)日：2012-05-24
申请号：PCT/US2011/061026
申请日：2011-11-16
申请人： TVA MEDICAL, INC. , MILLER, Gary, H. , BERMAN, Adam, L. , COHN, William, E. , MESTER, Dana, R. , JELICH, Damian, A.
发明人： MILLER, Gary, H. , BERMAN, Adam, L. , COHN, William, E. , MESTER, Dana, R. , JELICH, Damian, A.
IPC分类号： A61B17/11
CPC分类号： A61B18/1492 , A61B17/320016 , A61B17/320725 , A61B18/16 , A61B2017/00778 , A61B2017/00876 , A61B2017/22095 , A61B2017/320791 , A61B2018/00083 , A61B2018/00107 , A61B2018/00172 , A61B2018/00404 , A61B2018/00577 , A61B2018/00625 , A61B2018/1253 , A61B2018/144 , A61B2090/3925 , A61B2090/3966 , A61M1/3655
摘要： Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements.
摘要翻译：这里描述了用于在两个血管之间形成瘘的装置，系统和方法。通常，系统可以包括可包括瘘形成元件的第一导管。瘘形成元件可以包括一个或多个电极，机械切割元件，激光源或其组合，并且可以用于辅助瘘形成。在一些情况下，系统可以包括第二导管，其可以包括瘘形成元件。一个或多个导管可以包括一个或多个标记，磁性对准元件和/或一个形状变化元件。

2. 发明申请

WO2015138998A1 FISTULA FORMATION DEVICES AND METHODS THEREFOR 审中-公开
标题翻译：晶体形成装置及其方法
公开(公告)号：WO2015138998A1
公开(公告)日：2015-09-17
申请号：PCT/US2015/020604
申请日：2015-03-13
申请人： TVA MEDICAL, INC.
发明人： PATE, Thomas, Diffley
IPC分类号： A61M25/092
CPC分类号： A61M25/0127 , A61B17/11 , A61B18/1492 , A61B2017/00778 , A61B2017/00876 , A61B2018/00345 , A61B2018/00577 , A61B2018/00595 , A61M1/3655
摘要： Described here are devices, systems, and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter and a second catheter, which may comprise one or more fistula-forming elements. The first and second catheters may comprise one or more magnets, which may be used to assist in bringing the first and catheters in closer proximity to facilitate fistula formation. In some variations, the magnet may have a plurality of magnetic domains each characterized by a magnetic flux vector, with the magnetic flux vectors of the magnet passing through a common magnetic origin.
摘要翻译：这里描述了用于在两个血管之间形成瘘的装置，系统和方法。通常，系统可以包括第一导管和第二导管，其可以包括一个或多个瘘形成元件。第一和第二导管可以包括一个或多个磁体，其可以用于帮助使第一和导管更靠近以促进瘘形成。在一些变型中，磁体可以具有多个磁畴，每个磁畴的特征在于磁通矢量，其中磁体的磁通量矢量通过公共磁性原点。

3. 发明申请

WO2022115752A1 SYSTEMS, METHODS, AND CATHETERS FOR ENDOVASCULAR TREATMENT OF A BLOOD VESSEL 审中-公开
公开(公告)号：WO2022115752A1
公开(公告)日：2022-06-02
申请号：PCT/US2021/061118
申请日：2021-11-30
申请人： TVA MEDICAL, INC. , AKERELE-ALE, Oladipo Peter , MOLL, Andrew , PALMER, Alex , PALMER, Olivia R. , PEDE, Stephen , SIMPSON, Breanna
发明人： AKERELE-ALE, Oladipo Peter , MOLL, Andrew , PALMER, Alex , PALMER, Olivia R. , PEDE, Stephen , SIMPSON, Breanna
IPC分类号： A61B8/12 , A61B5/00 , A61B8/00 , A61B18/14 , A61B90/00 , A61M25/10
摘要： Systems, methods, and catheters for endovascular treatment of a blood vessel are disclosed. In one aspect, a catheter for endovascular treatment of a blood vessel. The catheter comprises a housing. The catheter further comprises a treatment portion. The catheter further comprises a fistula forming element. And the catheter further comprises an intravascular ultrasound imaging device.

4. 发明申请

WO2021221607A1 SYSTEMS, METHODS, AND CATHETERS FOR ENDOVASCULAR TREATMENT OF A BLOOD VESSEL 审中-公开
公开(公告)号：WO2021221607A1
公开(公告)日：2021-11-04
申请号：PCT/US2020/030178
申请日：2020-04-28
申请人： TVA MEDICAL, INC.
发明人： AKERELE-ALE, Oladipo Peter , SINGH, Aseem
IPC分类号： A61B17/11 , A61B18/04
摘要： Systems for forming a fistula between two blood vessels are provided. In embodiments, the system may include a catheter having a housing and a treatment portion coupled to the housing. The treatment portion may include a thermoelectric generator comprising an exposed surface exposed outside of the housing and a concealed surface opposite and electrically connected to the exposed surface. The thermoelectric generator may be configured to produce a temperature differential between the exposed surface and the concealed surface when an electric current is applied to one of the exposed surface and the concealed surface thereby producing the temperature differential between the exposed surface and the concealed surface such that the exposed surface is heated to a temperature greater than the concealed surface to weld the two blood vessels together.

5. 发明申请

WO2020242491A1 SYSTEMS, METHODS, AND CATHETERS FOR ENDOVASCULAR TREATMENT OF A BLOOD VESSEL 审中-公开
公开(公告)号：WO2020242491A1
公开(公告)日：2020-12-03
申请号：PCT/US2019/034896
申请日：2019-05-31
申请人： TVA MEDICAL, INC.
发明人： ZHENG, Peng , TESSMER, Alexander W. , COX, Jeremy B. , CHANDUSZKO, Andrzej J. , RANDALL, Michael , PATE, Thomas Diffley
IPC分类号： A61B8/12 , A61B8/08 , A61B8/00
摘要： In one aspect, a system for endovascular treatment of a blood vessel includes a control unit, an ultrasound device, an actuator, and a catheter having a treatment portion. The ultrasound device is communicatively coupled to the control unit. The ultrasound device includes an ultrasound probe having a subject contact surface. The actuator is coupled to the ultrasound probe and is operable to move the subject contact surface of the ultrasound prove relative to a treatment zone of a subject. The control unit is configured to determine a position of the treatment portion of the catheter as the catheter is advanced through the blood vessel, and move the subject contact surface of the ultrasound probe relative to the treatment zone of the subject with the actuator to follow the position of the catheter as the catheter is advanced through the blood vessel.

6. 发明申请

WO2018057095A1 VASCULAR STENT DEVICES AND METHODS 审中-公开
标题翻译：血管支架装置和方法
公开(公告)号：WO2018057095A1
公开(公告)日：2018-03-29
申请号：PCT/US2017/042937
申请日：2017-07-19
申请人： TVA MEDICAL, INC.
发明人： PATE, Thomas D. , COHN, William E.
IPC分类号： A61B17/00 , A61B17/11 , A61B18/00 , A61B18/04
摘要： Described here are devices, systems, and methods for cannulating a vessel. Generally, the method may comprise advancing a stent into a first vessel and deploying the stent in the first vessel to hold open one or more valves. This may permit retrograde blood flow through the blood vessel in peripheral vasculature and aid in cannulation of the blood vessel.
摘要翻译：这里描述的是用于插入血管的装置，系统和方法。通常，该方法可以包括将支架推进到第一容器中并且将支架展开在第一容器中以保持打开的一个或多个瓣膜。这可能允许逆行的血液流过外周脉管系统中的血管并且有助于血管的插管。

7. 发明申请

WO2017124062A1 DEVICES AND METHODS FOR FORMING A FISTULA 审中-公开
标题翻译：用于形成瘘管的装置和方法
公开(公告)号：WO2017124062A1
公开(公告)日：2017-07-20
申请号：PCT/US2017/013613
申请日：2017-01-15
申请人： TVA MEDICAL, INC.
发明人： PATE, Thomas, D. , MESTER, Dana, R. , COHN, William, E. , TETZLAFF, Philip, M.
IPC分类号： A61B18/14 , A61B18/16
CPC分类号： A61B18/1492 , A61B6/12 , A61B6/485 , A61B6/487 , A61B6/504 , A61B18/042 , A61B2017/00876 , A61B2018/00101 , A61B2018/00214 , A61B2018/00345 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/00875 , A61B2018/144 , A61B2090/3966 , A61M25/0108 , A61M25/0127 , A61M25/0662 , A61M39/06 , A61N1/05
摘要： Described here are devices, systems, and methods for forming a fistula between two blood vessels. The systems may comprise a first catheter including a housing and an electrode having a proximal end and a distal end. The proximal end is fixed relative to the housing and the distal end is longitudinally slidable within the housing.
摘要翻译：这里描述的是用于在两个血管之间形成瘘的装置，系统和方法。该系统可以包括第一导管，该第一导管包括壳体和具有近端和远端的电极。近端相对于壳体固定，并且远端在壳体内可纵向滑动。

8. 发明申请

WO2017124059A1 DEVICES AND METHODS FOR ADVANCING A WIRE 审中-公开
标题翻译：用于推进电线的设备和方法
公开(公告)号：WO2017124059A1
公开(公告)日：2017-07-20
申请号：PCT/US2017/013610
申请日：2017-01-15
申请人： TVA MEDICAL, INC.
发明人： COHN, William E. , PATE, Thomas D. , TETZLAFF, Philip M.
IPC分类号： A61M25/00 , A61M25/06 , A61M25/088 , A61M25/09 , A61M25/095
CPC分类号： A61M25/0194 , A61M25/09041 , A61M2025/018 , A61M2025/0197
摘要： Systems and methods for positioning a wire for advancement through a vessel wall, and advancing it through one or more vessel walls, generally include a delivery catheter and an alignment catheter or a receiving catheter, and a guidewire. In some variations, the systems and methods may be used to bypass an occlusion or other barrier that may prevent advancement of a wire or tools through an endoluminal space. In these variations, the systems and methods include a delivery catheter, a bypass catheter, a receiving catheter, and a guidewire. The delivery and receiving catheters each generally include a side aperture, a deflection surface, and an alignment element, and the bypass catheter generally includes two side apertures, two deflectors, and two alignment elements. In some variations, the systems and methods may assist in treatment of a patient suffering from critical limb ischemia.
摘要翻译：用于定位穿过血管壁推进的导丝并将其推进通过一个或多个血管壁的系统和方法通常包括输送导管和对准导管或接收导管以及导丝。在一些变型中，系统和方法可以用于绕过阻塞或其他屏障，其可以防止一个或多个导线通过腔内空间的前进。在这些变型中，系统和方法包括输送导管，旁路导管，接收导管和导丝。递送和接收导管各自通常包括侧孔，偏转表面和对准元件，并且旁路导管通常包括两个侧孔，两个偏转器和两个对准元件。在一些变型中，系统和方法可以帮助治疗患有严重肢体缺血的患者。

9. 发明申请

WO2016033374A1 CRYOLIPOPYSIS DEVICES AND METHODS THEREFOR 审中-公开
公开(公告)号：WO2016033374A1
公开(公告)日：2016-03-03
申请号：PCT/US2015/047274
申请日：2015-08-27
申请人： TVA MEDICAL, INC.
发明人： COHN, William, E. , PATE, Thomas, Diffley , BERMAN, Adam, L.
IPC分类号： A61B18/02
CPC分类号： A61M5/44 , A61M5/14 , A61M5/422
摘要： Described herein are cryolipolysis devices, systems, and methods for facilitating percutaneous access to a target blood vessel by performing cryolipolysis on subcutaneous adipose tissue obscuring the target blood vessel (e.g., a vessel used for hemodialysis treatment). Generally, the devices include a cooling member carrying a coolant that cools a selected portion of adipose tissue overlying the target blood vessel to reduce the selected portion of adipose tissue, thereby forming a depression in the adipose tissue and allowing the target blood vessel closer to the surface of the skin. In some variations, the cooling member is placed subcutaneously to directly cool the selected portion of adipose tissue. In other variations, the cooling member is placed external to the patient to indirectly cool the selected portion of adipose tissue through the skin.
摘要翻译：本文描述的是溶脂分解装置，系统和方法，用于通过对掩盖目标血管（例如，用于血液透析治疗的血管）的皮下脂肪组织进行冷冻脂解来促进经皮进入目标血管。通常，所述装置包括一个冷却部件，该冷却部件承载着冷却所述部分脂肪组织以覆盖目标血管以减少所选择的部分脂肪组织，由此在脂肪组织中形成凹陷，并允许目标血管更靠近皮肤表面。在一些变型中，将冷却构件皮下放置以直接冷却脂肪组织的选定部分。在其它变型中，将冷却构件放置在患者的外部，以通过皮肤间接地冷却脂肪组织的选定部分。

10. 发明申请

WO2022115109A1 CATHETER SYSTEMS WITH BIASING RAILS AND METHODS FOR FORMING FISTULAS 审中-公开
公开(公告)号：WO2022115109A1
公开(公告)日：2022-06-02
申请号：PCT/US2020/062556
申请日：2020-11-30
申请人： TVA MEDICAL, INC.
发明人： AKERELE-ALE, Oladipo Peter , MOLL, Andrew , PALMER, Alex , SIMPSON, Breanna , PALMER, Olivia Ruth
IPC分类号： A61B17/11 , A61M25/00 , A61B18/00
摘要： A system for forming a fistula, including a catheter including a catheter body, an electrode, one or more arrays of magnets, and a plurality of biasing rails. The one or more arrays of magnets are arranged longitudinally along the catheter body. The plurality of biasing rails extend along a length of the catheter body and are configured to radially arch away from the catheter body between a proximal point positioned proximal a first end of at least one array of magnets and a distal point positioned distal to a second end of the at least one array of magnets. The plurality of biasing rails bias the working site and the one or more arrays of magnets against a blood vessel wall. The plurality of biasing rails are joined by a connecting rail that laterally extends between the plurality of biasing rails.

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