专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

CA2865430A1 SYSTEMS AND METHODS FOR DETERMINING CONTAINER CONTENTS, LOCATIONS, AND SURROUNDINGS 未知
公开(公告)号：CA2865430A1
公开(公告)日：2013-08-29
申请号：CA2865430
申请日：2013-02-25
申请人： ADHERETECH INC , TRUSTEES OF THE UNIVERSITY OF ALABAMA FOR AND ON BEHALF OF THE UNIVERSITY OF ALABAMA IN HUNTSVILLE B
发明人： STEIN JOSHUA , LANGHAUSER JOHN , MORENA MICHAEL , JOVANOV EMIL
IPC分类号： A61J1/03 , A61J7/04 , G16H10/60
摘要： Systems and methods are provided for determining whether and/or when a patient is taking his or her medication and, when appropriate, providing reminders and/or alerts to the patient to improve adherence to a medication regimen. In some embodiments, a medication container is provided that includes a capacitance sensor for sensing the contents of the medication container (e.g., pill count or quantity of liquid medication). The capacitance sensor may include interleaved or interdigitated electrodes oriented vertically, horizontally, or angularly (e.g., diagonally) relative to an axis of the medication container. Reminders and/or alerts to the patient may be triggered based at least in part on the contents of the medication container, when a cap of the container was last opened and/or closed, the location of the medication container, and/or the container's surroundings.

2. 发明申请

WO2020037160A3 RAPID DIAGNOSTICS OF MYCOBACTERIA WITH LECTIN CONJUGATED PARTICLES 审中-公开
公开(公告)号：WO2020037160A3
公开(公告)日：2020-02-20
申请号：PCT/US2019/046719
申请日：2019-08-15
申请人： BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, FOR AND ON BEHALF OF THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , JAYAWARDENA, Hapuarachchige, Surangi , RATHNAYAKE, Kavini, Madushika , PATEL, Unnati , SENTELL, Andrew , JOHNSON, James , MUSTAIN, Melinda , DEVARASETTY, Veer Venkata, Naga Manohar
发明人： JAYAWARDENA, Hapuarachchige, Surangi , RATHNAYAKE, Kavini, Madushika , PATEL, Unnati , SENTELL, Andrew , JOHNSON, James , MUSTAIN, Melinda , DEVARASETTY, Veer Venkata, Naga Manohar
IPC分类号： C12N15/11 , C12Q1/68 , G01N33/52
摘要： The present disclosure is generally directed to methods and systems for the rapid detection of mycobacteria in samples using lectin-conjugated silica coated magnetic nanoparticles (SMNPs). In this work, carbohydrates on the cell wall of the mycobacteria serve as binding sites for lectins conjugated on the surface of lectin-conjugated SMNPs. As the target species of mycobacteria bind to lectin-conjugated SMNPs, a precipitate forms, which can be magnetically separated from the bulk test solution to visually indicate the presence of the target species of mycobacteria. The present disclosure is utilized as an inexpensive and rapid point of care system in one embodiment. In another embodiment, the methods and systems are integrated into a lateral flow assay for rapid detection of the target species of mycobacteria. In yet another embodiment, the methods and systems are utilized to create a microfluidic detection device with increased sensitivity to mycobacteria in a sample.

3. 发明申请

WO2020037160A2 RAPID DIAGNOSTICS OF MYCOBACTERIA WITH LECTIN CONJUGATED PARTICLES 审中-公开
公开(公告)号：WO2020037160A2
公开(公告)日：2020-02-20
申请号：PCT/US2019/046719
申请日：2019-08-15
申请人： BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, FOR AND ON BEHALF OF THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , JAYAWARDENA, Hapuarachchige, Surangi , RATHNAYAKE, Kavini, Madushika , PATEL, Unnati , SENTELL, Andrew , JOHNSON, James , MUSTAIN, Melinda , DEVARASETTY, Veer Venkata, Naga Manohar
发明人： JAYAWARDENA, Hapuarachchige, Surangi , RATHNAYAKE, Kavini, Madushika , PATEL, Unnati , SENTELL, Andrew , JOHNSON, James , MUSTAIN, Melinda , DEVARASETTY, Veer Venkata, Naga Manohar
IPC分类号： C12Q1/06
摘要： The present disclosure is generally directed to methods and systems for the rapid detection of mycobacteria in samples using lectin-conjugated silica coated magnetic nanoparticles (SMNPs). In this work, carbohydrates on the cell wall of the mycobacteria serve as binding sites for lectins conjugated on the surface of lectin-conjugated SMNPs. As the target species of mycobacteria bind to lectin-conjugated SMNPs, a precipitate forms, which can be magnetically separated from the bulk test solution to visually indicate the presence of the target species of mycobacteria. The present disclosure is utilized as an inexpensive and rapid point of care system in one embodiment. In another embodiment, the methods and systems are integrated into a lateral flow assay for rapid detection of the target species of mycobacteria. In yet another embodiment, the methods and systems are utilized to create a microfluidic detection device with increased sensitivity to mycobacteria in a sample.

4. 发明申请

WO2013126897A1 SYSTEMS AND METHODS FOR DETERMINING CONTAINER CONTENTS, LOCATIONS, AND SURROUNDINGS 审中-公开
标题翻译：用于确定集装箱内容，位置和环境的系统和方法
公开(公告)号：WO2013126897A1
公开(公告)日：2013-08-29
申请号：PCT/US2013/027664
申请日：2013-02-25
申请人： ADHERETECH INC. , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, FOR AND ON BEHALF OF THE UNIVERSITY OF ALABAMA IN HUNTSVILLE
发明人： STEIN, Joshua , LANGHAUSER, John , MORENA, Michael , JOVANOV, Emil
IPC分类号： A61J1/03 , A61J7/04
CPC分类号： A61J7/0409 , A61J7/0418 , A61J7/0481 , A61J2200/30 , A61J2200/70 , A61J2200/74 , A61J2200/76 , F04C2270/0421 , G06F19/00 , G06F19/3462 , G06Q10/10
摘要： Systems and methods are provided for determining whether and/or when a patient is taking his or her medication and, when appropriate, providing reminders and/or alerts to the patient to improve adherence to a medication regimen. In some embodiments, a medication container is provided that includes a capacitance sensor for sensing the contents of the medication container (e.g., pill count or quantity of liquid medication). The capacitance sensor may include interleaved or interdigitated electrodes oriented vertically, horizontally, or angularly (e.g., diagonally) relative to an axis of the medication container. Reminders and/or alerts to the patient may be triggered based at least in part on the contents of the medication container, when a cap of the container was last opened and/or closed, the location of the medication container, and/or the container's surroundings.
摘要翻译：提供了系统和方法，用于确定患者是否和/或何时服用他或她的药物，并且在适当时向患者提供提醒和/或警报以改善对药物治疗方案的依从性。在一些实施例中，提供了一种药物容器，其包括用于感测药物容器的内容物的电容传感器（例如，药片计数或液体药物的量）。电容传感器可以包括相对于药物容器的轴线垂直，水平或成角度地（例如，对角线）定向的交错或交叉指向的电极。至少部分地基于药物容器的内容触发对患者的提醒和/或警报，当容器的帽最后打开和/或关闭时，药物容器的位置和/或容器的位置环境。

5. 发明申请

WO2006119314A2 METHOD AND DEVICE FOR DETERMINING OXYGEN SATURATION OF HEMOGLOBIN, FOR DETERMINING HEMATOCRIT OF BLOOD, AND/OR FOR DETECTING MACULAR DEGENERATION 审中-公开
标题翻译：用于测定血红蛋白氧气饱和度的方法和装置，用于测定血液中的血红蛋白和/或用于检测黄变性
公开(公告)号：WO2006119314A2
公开(公告)日：2006-11-09
申请号：PCT/US2006/016883
申请日：2006-05-02
申请人： UAB RESEARCH FOUNDATION , THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , HILLMAN, Sharon , DENNINGHOFF, Kurt, R.
发明人： DENNINGHOFF, Kurt, R. , HILLMAN, Lloyd
IPC分类号： G01N33/50
CPC分类号： G01N33/4925 , G01N2021/3144 , G01N2021/3148
摘要： A method and device for accurately determining oxygen saturation of hemoglobin by the measurement of the optical density of a sample, such as a blood vessel, in response to illumination by light having at least three wavelengths (λi, λ2, λ3, ...) within a range of about 460 nm to about 523 nm. The hematocrit of a sample may be determined from optical density measurements at the three or more wavelengths in conjunction with a known path length. The device may be an intravenous or intra-arterial fiber optic catheter used to deliver the interrogating light signal to the blood and to detect the reflected signal. A method and device of determining the thickness of the retinal well using spectroscopic information are also disclosed.
摘要翻译：通过测量诸如血管的样品的光密度来响应于具有至少三个波长（λi，λ2，θ3，...的光）的照明来精确地确定血红蛋白的氧饱和度的方法和装置。 ..）在约460nm至约523nm的范围内。样品的血细胞比容可以通过结合已知的路径长度在三个或更多个波长处的光密度测量来确定。该装置可以是用于将询问光信号传递到血液并检测反射信号的静脉内或动脉内纤维导管。还公开了使用光谱信息确定视网膜的厚度的方法和装置。

6. 发明申请

WO2006085934A2 RAB9 PROTEIN CRYSTAL STRUCTURES AND METHODS FOR IDENTIFYING RAB9 MODULATORS 审中-公开
标题翻译： RAB9蛋白晶体结构和识别RAB9调节剂的方法
公开(公告)号：WO2006085934A2
公开(公告)日：2006-08-17
申请号：PCT/US2005/021191
申请日：2005-06-16
申请人： THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , MEEHAN, Edward, J. , CHEN, Liqing , DIGIAMMARINO, Enrico, L. , HODGE, Thomas, W.
发明人： MEEHAN, Edward, J. , CHEN, Liqing , DIGIAMMARINO, Enrico, L. , HODGE, Thomas, W.
IPC分类号： G01N33/48 , C12N9/12 , G06F19/00
CPC分类号： C12N9/16 , C07K2299/00 , G01N2500/04
摘要： The present invention relates to crystalline Rab9 in complex with either GDP or the GTP analog Guanosine 5'-(β, γ-imido) triphosphate (GppNHp), the three dimensional coordinates and structures of Rab9 in Rab9-GDP and Rab9-GppNHp complexes, and uses thereof for drug design. In particular, the present invention relates to methods for producing Rab9 crystals of sufficient quality to obtain a determination of the three dimensional structure of Rab9 to a high resolution in both its GTP-bound (on/active) and GDP-bound (off/inactive) conformations. The present invention also relates to a computer-readable medium encoded with the three dimensional coordinates of Rab9 in Rab9-GDP and Rab9-GppNHp complexes wherein, using a graphical display software program, the three dimensional coordinates create an electronic file that can be visualized on a computer capable of representing the electronic file as a three dimensional image.
摘要翻译：本发明涉及与GDP或GTP类似物鸟苷5' - （β，β-亚氨基）三磷酸（GppNHp）复合的结晶Rab9，Rab9-GDP和Rab9-GppNHp复合物中Rab9的三维坐标和结构，并将其用于药物设计。特别地，本发明涉及用于生产足够质量的Rab9晶体的方法，以在其GTP结合（开/主动）和GDP-结合（关/非活性）两者中获得Rab9的三维结构确定为高分辨率）构象。本发明还涉及用Rab9-GDP和Rab9-GppNHp复合物中的Rab9的三维坐标编码的计算机可读介质，其中使用图形显示软件程序，三维坐标创建可以在能够将电子文件表示为三维图像的计算机。

7. 发明申请

WO2002063070A1 NICKEL COBALT PHOSPHOROUS LOW STRESS ELECTROPLATING 审中-公开
标题翻译：镍钴钴磷光体低压电镀
公开(公告)号：WO2002063070A1
公开(公告)日：2002-08-15
申请号：PCT/US2001/004296
申请日：2001-02-08
申请人： THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , UNITED STATES GOVERNMENT , ENGELHAUPT, Darell, E. , RAMSEY, Brian, D.
发明人： ENGELHAUPT, Darell, E. , RAMSEY, Brian, D.
IPC分类号： C25D3/16
CPC分类号： C25D3/12 , C25D3/562
摘要： An electrolytic plating process is provided for electrodepositing a nickel or nickel cobalt alloy which contains at least 2 % to 25 % by atomic volume of phosphorous. The process solution contains nickel and optionally cobalt sulfate, hypophosphorous acid or a salt thereof, boric acid or a salt thereof, a monodentate organic acid or a salt thereof, and a multidentate organic acid or a salt thereof. The pH of the plating bath is from about 3.0 to about 4.5. An electroplating process is also provided which includes electroplating from the bath a nickel cobalt phosphorous alloy. This process can achieve a deposit with high microyield of at least about 84 kg/mm 2 (120 ksi) and a density lower than pure nickel of about 8.0 gm/cc. This process can be used to plate a deposit of essentially zero stress at plating temperatures from ambient to 70 °C.
摘要翻译：提供一种电解电镀方法，用于电沉积含有至少2％至25％原子体积的磷的镍或镍钴合金。该工艺溶液含有镍和任选的硫酸钴，次磷酸或其盐，硼酸或其盐，单齿有机酸或其盐，以及多齿有机酸或其盐。电镀浴的pH为约3.0至约4.5。还提供了一种电镀工艺，其中包括从镀浴中电镀镍钴磷合金。该过程可以实现至少约84kg / mm 2（120ksi）的高微量玻璃沉积物和低于约8.0gm / cc的纯镍的密度。该方法可用于在从室温至70℃的电镀温度下对基本上为零的应力沉积。

8. 发明申请

WO2013033665A9 A METHOD OF FACILITATING THE BIOCONVERSION OF CRUDE BIODIESEL-DERIVED GLYCEROL BY MICROORGANISMS 审中-公开
公开(公告)号：WO2013033665A9
公开(公告)日：2013-03-07
申请号：PCT/US2012/053563
申请日：2012-09-01
申请人： THE BOARD OF TRUSTREES OF UNIVERSITY OF ALABAMA, FOR AND ON BEHALF OF THE UNIVERSITY OF ALABAMA, IN HUNTSVILLE , SCHOLZ, Carmen , VENKATARAMANAN, Keerthi, Prasad , BOTHUN, Geoffrey, D.
发明人： SCHOLZ, Carmen , VENKATARAMANAN, Keerthi, Prasad , BOTHUN, Geoffrey, D.
IPC分类号： C07C31/22
摘要： The present disclosure generally pertains to a method of facilitating the bioconversion of glycerol by microorganisms. In one embodiment, biodiesel derived crude glycerol is purified by removing fatty acids through acid precipitation. The fatty acid-free crude glycerol is then utilized as a carbon source for the culture of microorganisms and the production of value added substances. Additionally, the unsaturated fatty acids within the biodiesel-derived crude glycerol are converted to saturated fatty acids, allowing for fermentation behavior similar to that of pure glycerol. Both the cultured microorganisms and the culture media containing the purified crude glycerol may be analyzed for crude glycerol bioconversion products. The disclosure also relates to a method of increasing product yield through the addition of a second carbon source to the microorganism culture media.

9. 发明申请

WO2003035970A1 A METHOD FOR PREPARING A HOMOGENOUS CELLULOSIC PRODUCT FROM CELLULOSIC WASTE MATERIALS 审中-公开
标题翻译：从细胞废物材料制备均匀的细胞产物的方法
公开(公告)号：WO2003035970A1
公开(公告)日：2003-05-01
申请号：PCT/US2001/050049
申请日：2001-10-22
申请人： THE UNIVERSITY OF ALABAMA IN HUNTSVILLE , ELEY, Michael, H.
发明人： ELEY, Michael, H.
IPC分类号： D21C5/02
CPC分类号： D21C5/02 , A61L11/00 , B09B3/0075 , Y02W30/648
摘要： A method for treating diverse pulp and paper materials, including such products contained in municipal solid waste and biohazardous wastes, to produce a homogenous cellulosic product comprises the steps of feeding diverse pulp and paper materials into a vessel, introducing steam into the vessel while agitating the materials, purging the gases from the vessel while agitating the materials, sealing the vessel so that the vessel is pressure tight, saturating the materials with steam at sufficient temperature and pressure to expand the physical and chemical structure of the materials, while agitating the materials, depressurizing the vessel to further enhance the physical and chemical expansion of the materials, and discharging the processed products. Alternatively, the method can be performed without purging the gases, if the temperature in the range of about 140 °C to about 160 °C, and the pressure is in the range of about 275 to 450 kPa. During the optional purging step, during the depressurization step, and during the optional evacuation step, volatile organic compounds and other air pollutants can be captured and treated. The temperature, pressure, and process time is more than sufficient to decontaminate and sterilize biohazardous laboratory and medical wastes.
摘要翻译：用于处理各种纸浆和纸材料的方法，包括城市固体废物和生物危害废物中所含的这些产品，以产生均匀的纤维素产品包括以下步骤：将不同的纸浆和纸材料进料到容器中，将蒸汽引入容器中同时搅拌材料，同时在搅拌材料的同时从容器中清除气体，密封容器，使容器压力紧密，在足够的温度和压力下用蒸汽使材料饱和，以在搅拌材料的同时扩大材料的物理和化学结构，对容器进行减压以进一步增强材料的物理和化学膨胀，并排出加工产品。或者，如果温度在约140℃至约160℃的范围内，并且压力在约275至450kPa的范围内，则可以在不吹扫气体的情况下进行该方法。在可选的清洗步骤期间，在减压步骤期间和在可选的抽空步骤期间，可以捕获并处理挥发性有机化合物和其它空气污染物。温度，压力和加工时间足以对生物危害实验室和医疗废物进行净化和灭菌。

10. 发明申请

WO2020007884A1 DISPOSITIF DE COMPENSATION ELECTRIQUE ACTIVE 审中-公开
公开(公告)号：WO2020007884A1
公开(公告)日：2020-01-09
申请号：PCT/EP2019/067779
申请日：2019-07-02
申请人： ENSEA - ECOLE NATIONALE SUPÉRIEURE DE L'ELECTRONIQUE ET DE SES APPLICATIONS , THE UNIVERSITY OF ALABAMA IN HUNTSVILLE
发明人： ALALI, Mohamad Alaa Eddin , SHTESSEL, Yuri , BARBOT, Jean-Pierre
IPC分类号： H02J3/01 , H02J3/14 , H02J3/18 , H02J3/38 , H02M1/12
摘要： L'invention concerne un dispositif de compensation (7) de courant apte à être connecté, en parallèle, entre un réseau électrique (1) et des charges (2) électriques non linéaires et linéaires, et en aval d'au moins une unité de puissance à génération d'énergie renouvelable (100) couplée à un élément de stockage d'énergie (3), le dispositif de compensation (7) comportant : - une unité de conversion (8) de puissance comportant au moins un onduleur de tension (9) apte à générer un courant alternatif, - une unité de filtrage (10) de sortie, comportant un filtre (11) dimensionné pour bloquer les composantes harmoniques dues à la commutation de l'onduleur (9), - une unité de contrôle-commande (12) comprenant une unité de calcul (25) des courants de référence et un dispositif de pilotage de commutation (21) qui commande la commutation de l'onduleur (9) en fonction de l'identification des courants par l'unité de calcul (25) des courants de référence.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式