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1. 发明专利

AU2585799A Non-invasive optical measurement of blood hematocrit 未知
公开(公告)号：AU2585799A
公开(公告)日：1999-08-23
申请号：AU2585799
申请日：1999-02-04
申请人： UNIV MASSACHUSETTS , POLESTAR TECHNOLOGIES INC
发明人： SOLLER BABS R , MICHEELS RONALD H
IPC分类号： A61B5/00 , G01N15/06 , G01N21/25

2. 发明申请

WO2008144031A2 MULTILAYERED OPTICAL SENSING PATCH AND RETAINING PLUG THEREFOR 审中-公开
标题翻译：多层光学传感器及其保留插件
公开(公告)号：WO2008144031A2
公开(公告)日：2008-11-27
申请号：PCT/US2008/006383
申请日：2008-05-15
申请人： POLESTAR TECHNOLOGIES, INC. , KANE, James, A.
发明人： KANE, James, A.
IPC分类号： G01N21/75 , G01N21/80
CPC分类号： G01N21/77 , G01N21/6428 , G01N2021/7786
摘要： A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition immobilized on or within the porous polymer substrate membrane. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage.
摘要翻译：提供了用于测量容器内的诸如pH，氧含量等条件的多层光学传感贴片。本发明的多层光学感测贴片由可热封的聚合物基底层和稍后附着于其上的聚合物感测膜组成。聚合物感测膜层由多孔聚合物支撑膜和固定在多孔聚合物基底膜上或其内的光学感测组合物形成。可热封的聚合物基底层能够牢固地结合到生物反应器袋的内层以及多孔聚合物支撑基底层。此外，多孔聚合物支撑膜层为聚合物感测层提供牢固的支撑结构，由此保护其中设置的光学感测组合物不会降解/损坏。

3. 发明申请

WO2013067329A1 METHODS AND SYSTEMS FOR DETECTION AND IDENTIFICATION OF CONCEALED MATERIALS 审中-公开
标题翻译：用于检测和鉴定隐蔽材料的方法和系统
公开(公告)号：WO2013067329A1
公开(公告)日：2013-05-10
申请号：PCT/US2012/063292
申请日：2012-11-02
申请人： POLESTAR TECHNOLOGIES, INC. , KANE, James, A. , SHASHIDHAR, Ranganathan
发明人： KANE, James, A. , SHASHIDHAR, Ranganathan
IPC分类号： G01V3/12 , G01V3/08 , G01V3/38
CPC分类号： G01V5/0016
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation, source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, aftex" processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of pi-ocessed data is compared to a predetermined vector corresponding to a ρχ-edetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括分析子系统，其被配置为处理多个像素化图像，通过用电磁辐射反复照射区域获得的像素化图像的数量，来自多个电磁辐射源的源，每个重复以不同波长执行。像素化图像的数量，“最大”处理，构成从多个像素的每个像素处理的数据的向量。在每个像素处，将加工数据的向量与对应于确定的材料的预定向量进行比较，通过比较确定预定材料的存在。

4. 发明申请

WO2008140473A2 OPTICAL SYSTEM AND METHOD FOR INSPECTION AND CHARACTERIZATION OF LIQUIDS IN VESSELS 审中-公开
标题翻译：光学系统和用于液体检测和表征的方法
公开(公告)号：WO2008140473A2
公开(公告)日：2008-11-20
申请号：PCT/US2007/022656
申请日：2007-10-26
申请人： POLESTAR TECHNOLOGIES, INC. , MICHEELS, Ronald, H. , SHASHIDHAR, Ranganathan , CARPENTER, Karen, K.
发明人： MICHEELS, Ronald, H. , SHASHIDHAR, Ranganathan , CARPENTER, Karen, K.
IPC分类号： G01J3/00 , G01N31/00
CPC分类号： G01N21/359 , G01J3/42 , G01J2003/1213 , G01N21/3577
摘要： A system and method for non-invasively inspecting one or more vessels capable of transmitting IR light containing liquid is provided, which uses a near-infrared (NIR) imaging device in combination with one or two NIR light sources, a diffuser plate, and an optical wavelength selecting means is provided for selecting one or more wavelength bands. In addition, the system may further comprise a computer processing means, a computer database containing known absorbance values, and a computer application, such that the system may compare the collected spectroscopic data to known spectroscopic data, and identify the liquid contained within the inspected vessel. The inspection method of the present invention measures a transmission or reflection image of one or more vessels being inspected at one or more narrow wavelength intervals in the NIR spectral range that corresponds to a peak absorbance wavelength of water, organic liquids, and explosive compositions.
摘要翻译：提供了一种用于非侵入性地检查一个或多个能够透射包含液体的IR光的器皿的系统和方法，其使用近红外（NIR）成像器件与一个或两个NIR光源，扩散板和光波长选择装置，用于选择一个或多个波长带。此外，该系统可以进一步包括计算机处理装置，含有已知吸光度值的计算机数据库和计算机应用程序，使得该系统可以将收集的光谱数据与已知的光谱数据进行比较，并且识别包含在被检查的容器内的液体。本发明的检查方法在NIR光谱范围内的一个或多个窄波长间隔处测量一个或多个被检查的容器的透射或反射图像，其对应于水，有机液体和爆炸性组合物的峰值吸收波长。 / p>

5. 发明申请

WO2009140559A1 MULTILAYERED OPTICAL SENSING PATCH AND RETAINING PLUG THEREFOR 审中-公开
标题翻译：多层光学传感器及其保留插件
公开(公告)号：WO2009140559A1
公开(公告)日：2009-11-19
申请号：PCT/US2009/044048
申请日：2009-05-15
申请人： POLESTAR TECHNOLOGIES, INC. , KANE, James, A.
发明人： KANE, James, A.
IPC分类号： G01N21/75 , G01N21/76 , G01N21/78 , G01N21/80
CPC分类号： G01N21/78 , G01N21/80 , G01N2021/773 , G01N2021/7786
摘要： A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition (comprising a reactive indicator) covalently bonded thereto. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage.
摘要翻译：提供了用于测量容器内的诸如pH，氧含量等条件的多层光学传感贴片。本发明的多层光学感测贴片由可热封的聚合物基底层和稍后附着于其上的聚合物感测膜组成。聚合物感测膜层由多孔聚合物支撑膜和与其共价键合的光学感测组合物（包括反应性指示剂）形成。可热封的聚合物基底层能够牢固地结合到生物反应器袋的内层以及多孔聚合物支撑基底层。此外，多孔聚合物支撑膜层为聚合物感测层提供牢固的支撑结构，由此保护其中设置的光学感测组合物不会降解/损坏。

6. 发明申请

WO2008144031A3 MULTILAYERED OPTICAL SENSING PATCH AND RETAINING PLUG THEREFOR 审中-公开
标题翻译：多层光学传感器及其保留插件
公开(公告)号：WO2008144031A3
公开(公告)日：2009-01-15
申请号：PCT/US2008006383
申请日：2008-05-15
申请人： POLESTAR TECHNOLOGIES INC , KANE JAMES A
发明人： KANE JAMES A
IPC分类号： G01N21/75 , G01N21/80
CPC分类号： G01N21/77 , G01N21/6428 , G01N2021/7786
摘要： A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition immobilized on or within the porous polymer substrate membrane. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage.
摘要翻译：提供了用于测量容器内的诸如pH，氧含量等条件的多层光学传感贴片。本发明的多层光学感测贴片由可热封的聚合物基底层和稍后附着于其上的聚合物感测膜组成。聚合物感测膜层由多孔聚合物支撑膜和固定在多孔聚合物基底膜上或其内的光学感测组合物形成。可热封的聚合物基底层能够牢固地结合到生物反应器袋的内层以及多孔聚合物支撑基底层。此外，多孔聚合物支撑膜层为聚合物感测层提供牢固的支撑结构，由此保护其中设置的光学感测组合物不会降解/损坏。

7. 发明申请

WO2008140473A3 OPTICAL SYSTEM AND METHOD FOR INSPECTION AND CHARACTERIZATION OF LIQUIDS IN VESSELS 审中-公开
标题翻译：用于船舶液体检测和表征的光学系统和方法
公开(公告)号：WO2008140473A3
公开(公告)日：2008-12-31
申请号：PCT/US2007022656
申请日：2007-10-26
申请人： POLESTAR TECHNOLOGIES INC , MICHEELS RONALD H , SHASHIDHAR RANGANATHAN , CARPENTER KAREN K
发明人： MICHEELS RONALD H , SHASHIDHAR RANGANATHAN , CARPENTER KAREN K
IPC分类号： G01N21/00
CPC分类号： G01N21/359 , G01J3/42 , G01J2003/1213 , G01N21/3577
摘要： A system and method for non-invasively inspecting one or more vessels capable of transmitting IR light containing liquid is provided, which uses a near-infrared (NIR) imaging device in combination with one or two NIR light sources, a diffuser plate, and an optical wavelength selecting means is provided for selecting one or more wavelength bands. In addition, the system may further comprise a computer processing means, a computer database containing known absorbance values, and a computer application, such that the system may compare the collected spectroscopic data to known spectroscopic data, and identify the liquid contained within the inspected vessel. The inspection method of the present invention measures a transmission or reflection image of one or more vessels being inspected at one or more narrow wavelength intervals in the NIR spectral range that corresponds to a peak absorbance wavelength of water, organic liquids, and explosive compositions.
摘要翻译：提供了一种用于非侵入性地检查能够发射含有红外光的液体的一个或多个容器的系统和方法，其使用近红外（NIR）成像装置与一个或两个NIR光源，漫射板和提供了用于选择一个或多个波长带的光波长选择装置。此外，该系统还可以包括计算机处理装置，包含已知吸光度值的计算机数据库和计算机应用程序，使得系统可以将收集的光谱数据与已知的光谱数据进行比较，并且识别被检查的容器中所含的液体。本发明的检查方法测量在对应于水，有机液体和炸药组合物的峰值吸收波长的NIR光谱范围内以一个或多个窄波长间隔检查的一个或多个容器的透射或反射图像。

8. 发明公开

EP0874582A1 OPTICAL MEASUREMENT OF TISSUE pH 失效
标题翻译：光学测量生物体组织的pH值
公开(公告)号：EP0874582A1
公开(公告)日：1998-11-04
申请号：EP96943495.0
申请日：1996-11-08
申请人： University of Massachusetts , Polestar Technologies, Inc.
发明人： University of Massachusetts , Polestar Technologies, Inc.
IPC分类号： A61B5
CPC分类号： A61B5/14539 , A61B5/0075 , A61B5/0086
摘要： The invention provides an optical method and apparatus for determining the pH of a tissue (71). The method includes the step of first irradiating the tissue (71) with optical radiation (74). The radiation (74) may first pass through skin covering the tissue (71) of interest, or may irradiate the tissue (71) directly. Radiation reflected (90) from the tissue (71) is then collected to determine a reflection spectrum (step 18). pH is then determined by comparing this spectrum to a mathematical model relating optical properties to pH of the tissue (steps 20 and 22).

9. 发明公开

EP0874582A4 OPTICAL MEASUREMENT OF TISSUE pH 失效
标题翻译：光学测量生物体组织的pH值
公开(公告)号：EP0874582A4
公开(公告)日：1999-01-07
申请号：EP96943495
申请日：1996-11-08
申请人： UNIV MASSACHUSETTS , POLESTAR TECHNOLOGIES INC
发明人： UNIVERSITY OF MASSACHUSETTS , POLESTAR TECHNOLOGIES INC
IPC分类号： A61B5/00 , A61B6/00
CPC分类号： A61B5/14539 , A61B5/0075 , A61B5/0086
摘要： The invention provides an optical method and apparatus for determining the pH of a tissue (71). The method includes the step of first irradiating the tissue (71) with optical radiation (74). The radiation (74) may first pass through skin covering the tissue (71) of interest, or may irradiate the tissue (71) directly. Radiation reflected (90) from the tissue (71) is then collected to determine a reflection spectrum (step 18). pH is then determined by comparing this spectrum to a mathematical model relating optical properties to pH of the tissue (steps 20 and 22).

10. 发明授权

US08685745B2 Multilayered optical sensing patch and retaining plug therefor 有权
标题翻译：多层光学传感贴片及其固定插头
公开(公告)号：US08685745B2
公开(公告)日：2014-04-01
申请号：US13281647
申请日：2011-10-26
申请人： James A. Kane
发明人： James A. Kane
IPC分类号： G01N21/77
CPC分类号： G01N21/77 , G01N31/22 , G01N2021/7786
摘要： A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition (comprising a reactive indicator) covalently bonded thereto. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage.
摘要翻译：提供了用于测量容器内的诸如pH，氧含量等条件的多层光学传感贴片。本发明的多层光学感测贴片由可热封的聚合物基底层和稍后附着于其上的聚合物感测膜组成。聚合物感测膜层由多孔聚合物支撑膜和与其共价键合的光学感测组合物（包括反应性指示剂）形成。可热封的聚合物基底层能够牢固地结合到生物反应器袋的内层以及多孔聚合物支撑基底层。此外，多孔聚合物支撑膜层为聚合物感测层提供牢固的支撑结构，由此保护其中设置的光学感测组合物不会降解/损坏。

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