专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2019019145A 抗癌療法としての正常細胞および腫瘍細胞の小分子ＴＲＡＩＬ遺伝子誘導审中-公开
公开(公告)号：JP2019019145A
公开(公告)日：2019-02-07
申请号：JP2018210558
申请日：2018-11-08
申请人： PENN STATE RES FOUND
发明人： WAFIK S EL-DEIRY , JOSHUA E ALLEN , WU GEN SHENG
IPC分类号： A61K31/519 , A61K31/337 , A61K39/395 , A61K45/00 , A61P35/00 , A61P43/00 , C07D471/14
摘要：【課題】抗癌療法としての正常細胞および腫瘍細胞の小分子TRAIL遺伝子誘導を提供すること。【解決手段】TIC10に関する方法および組成物が本発明の態様に従って記載される。その組成物および方法は、疾患、特に癌の処置を必要とする被験体(ヒト被験体ならびに他の種の被験体を含む)において、そのような疾患を処置する際の有用性を有する。その組成物は、脳腫瘍の処置を必要とする被験体において脳腫瘍を処置する際の有用性を有する。本発明の態様によると、癌を有するかまたは有するリスクがある被験体を処置する方法が提供され、その方法は、薬学的に有効な量のTIC10またはその薬学的に許容され得る塩、水和物もしくは溶媒和物;および薬学的に許容され得るキャリアを投与する工程を包含する。【選択図】なし

2. 发明专利

JPH1066724A ARTIFICIAL HEART ASSEMBLY AND ITS DRIVING METHOD 失效
公开(公告)号：JPH1066724A
公开(公告)日：1998-03-10
申请号：JP32005796
申请日：1996-11-29
申请人： PENN STATE RES FOUND THE
发明人： SNYDER ALAN J
IPC分类号： A61M1/10 , F04B43/09 , F04B49/06
摘要： PROBLEM TO BE SOLVED: To properly apply a brake to a pumping mechanism. SOLUTION: An artificial-heart assembly, which can be a total artificial heart or a ventricle aid device designed to be embedded into a subject, has a pumping mechanism for pumping blood from a blood input conduit to a blood output conduit and a means for reverse driving the pumping mechanism in the opposite direction over a stroke having a length specified by a pair of terminal points. The drive means has a means for comparing the actual speed of the pumping mechanism with braking speed and a means for selectively applying a brake to a motor according to the relative magnitudes of the actual speed and the braking speed.

3. 发明专利

JPH10508288A 失效
公开(公告)号：JPH10508288A
公开(公告)日：1998-08-18
申请号：JP50669496
申请日：1995-07-31
申请人： US HEALTH , ARCH DEV CORP , PENN STATE RES FOUND
IPC分类号： A61K31/505 , A61K31/52 , A61K31/522 , A61K31/53 , A61P35/00 , A61P43/00 , C07D239/46 , C07D239/47 , C07D239/48 , C07D239/50 , C07D251/52 , C07D473/06 , C07D473/18 , C07D473/40 , C07D487/04

4. 发明专利

JP2001100200A REFLECTIVE LIQUID CRYSTAL DISPLAY DEVICE 失效
公开(公告)号：JP2001100200A
公开(公告)日：2001-04-13
申请号：JP2000277765
申请日：2000-09-13
申请人： SAMSUNG SDI CO LTD , PENN STATE RES FOUND
发明人： YU JONGUN , J S PEITERU , KIMU YONJIN , SO SONU
IPC分类号： G02F1/137 , G02F1/1335 , G02F1/1337 , G02F1/1343 , G02F1/141 , G09F9/00
摘要： PROBLEM TO BE SOLVED: To provide a reflective liquid crystal display device utilizing a ferroelectric liquid crystal. SOLUTION: The reflective liquid crystal display device comprises a transparent first substrate with inside and outside surfaces, a polarizing plate with a polarization direction in a first direction attached on the outside surface of the first substrate, a transparent first electrode formed on the inside surface of the first substrate, a first alignment film formed on the first electrode aligning liquid crystal molecules in a second direction, a second substrate placed opposite to the inside surface of the first substrate with inside and outside surfaces, a second electrode formed on the inside surface of the second substrate simultaneously functioning as a reflection plate, a second alignment film formed on the second electrode aligning the liquid crystal molecules in a third direction different from the second direction and a ferroelectric liquid crystal layer injected between the first and second alignment films. In the device, the directions to which the liquid crystal molecules in the ferroelectric liquid crystal layer are oriented twist from the second to the third direction as the molecules go from the first to the second alignment film surface.

5. 发明专利

JPH0881788A METHOD OF PERFORMING CONTROLLED ETCHING OF OXIDE BY GAS PHASE REACTION 失效
公开(公告)号：JPH0881788A
公开(公告)日：1996-03-26
申请号：JP8635995
申请日：1995-03-17
申请人： PENN STATE RES FOUND
发明人： ROBAATO DABURIYU GURANTO , JIYAAJII RUTSUITSURO , KEBIN TORETSUKU
IPC分类号： C30B33/12 , B08B6/00 , C23F1/12 , H01L21/302 , H01L21/311 , H01L21/306

6. 发明公开

KR20180067554A 냉간 소결 세라믹 및 복합물 审中-公开
公开(公告)号：KR20180067554A
公开(公告)日：2018-06-20
申请号：KR20187011458
申请日：2016-09-26
申请人： PENN STATE RES FOUND
发明人： RANDALL CLIVE A , GUO JING , BAKER AMANDA , LANAGAN MICHAEL , GUO HANZHENG
IPC分类号： C04B35/64 , C04B35/622 , C04B35/626 , C04B35/632
CPC分类号： C04B37/006 , B32B18/00 , C04B35/2683 , C04B35/447 , C04B35/453 , C04B35/4682 , C04B35/486 , C04B35/495 , C04B35/5152 , C04B35/6261 , C04B35/6263 , C04B35/6264 , C04B35/62685 , C04B35/634 , C04B35/645 , C04B2235/3201 , C04B2235/3203 , C04B2235/3256 , C04B2235/3258 , C04B2235/3274 , C04B2235/442 , C04B2235/444 , C04B2235/448 , C04B2235/5436 , C04B2235/5445 , C04B2235/5454 , C04B2235/6025 , C04B2235/77 , C04B2237/125 , C04B2237/34
摘要： 물질의저온소결공정은, 입자형태의적어도하나의무기화합물, 예를들어, 세라믹과, 상기무기화합물을부분적으로용해할수 있는용매를조합시켜혼합물을형성하는조합단계; 및상기혼합물에압력및 저온을적용하여상기용매를증발시키고및 상기적어도하나의무기화합물을밀도를높여소결물질을형성하는, 압력및 저온의적용단계를포함한다.

7. 发明申请

WO2016195982A3 HEPATITIS B VIRUS CAPSID ASSEMBLY 审中-公开
标题翻译： HEPATITIS B病毒CAPSID大会
公开(公告)号：WO2016195982A3
公开(公告)日：2017-01-05
申请号：PCT/US2016032691
申请日：2016-05-16
申请人： PENN STATE RES FOUND
发明人： HU JIANMING
IPC分类号： G01N33/576
CPC分类号： C12Q1/706 , C07K14/005 , C12N7/00 , C12N2730/10122 , G01N33/56983 , G01N33/5762 , G01N2333/005 , G01N2500/20
摘要： Cell-free translation and assembly systems allow for HBV capsid assembly under cell-free conditions that also mimic the physiological salt and protein concentrations. These hepatitis virus capsid assembly systems utilize the C-terminal domain (CTD) and N-terminal domain (NTD) of the hepatitis capsid protein in capsid assembly. Uses of the system include the identification of potential new therapeutic strategies and screening of potential therapeutic agents which target these domains and modulate capsid assembly and/or disassembly and other functions of these domains in HBV replication and pathogenesis.
摘要翻译：无细胞翻译和组装系统允许在无细胞条件下也可模拟生理盐和蛋白质浓度的HBV衣壳装配。这些肝炎病毒衣壳装配系统利用衣壳装配中的肝炎衣壳蛋白的C末端结构域（CTD）和N-末端结构域（NTD）。系统的使用包括鉴定潜在的新治疗策略和筛选靶向这些结构域的潜在治疗剂，并调节这些结构域在HBV复制和发病机制中的衣壳装配和/或拆解等功能。

8. 发明申请

WO2015199791A3 SELF-HEALABLE COATINGS AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：自我保护涂料及其制备方法
公开(公告)号：WO2015199791A3
公开(公告)日：2016-04-07
申请号：PCT/US2015025422
申请日：2015-04-10
申请人： PENN STATE RES FOUND
发明人： WANG JING , WONG TAK-SING
IPC分类号： B05D3/12 , B01L3/00 , B05D5/08 , C09D5/16
CPC分类号： C10M107/50 , A01N25/08 , C09D5/00 , C10M105/76 , C10M2227/04
摘要： A robust and self-healing coating has been developed by incorporating a thermally self-healing chemical coating on smooth and/or roughened solid. When the chemically coated solid is combined with a lubricating fluid, the material system is capable to repel a broad range of liquids and solids. The thermally self-healing chemical coating may be applied on various industrial metals, glass and plastics, and has shown exceptionally physical and chemical robustness as compared to state-of-the-art liquid-repellent coatings.
摘要翻译：通过在光滑和/或粗糙的固体上引入热自愈化学涂层，开发出坚固且自愈的涂层。当化学涂覆的固体与润滑流体结合时，材料体系能够排斥广泛的液体和固体。热自愈化学涂层可以应用于各种工业金属，玻璃和塑料，并且与现有技术的防液涂层相比，具有特别的物理和化学稳定性。

9. 发明申请

WO2015006684A3 APPARATUSES AND METHODS FOR MODULATING FLUIDS USING ACOUSTICALLY OSCILLATING SOLID STRUCTURES 审中-公开
标题翻译：使用声振荡固体结构调节流体的装置和方法
公开(公告)号：WO2015006684A3
公开(公告)日：2015-11-12
申请号：PCT/US2014046334
申请日：2014-07-11
申请人： PENN STATE RES FOUND
发明人： HUANG PO-HSUN , HUANG TONY JUN
IPC分类号： B01F11/02
CPC分类号： F04B19/006
摘要： An acoustofluidic apparatus is provided that functions by the generation of microstreaming in fluid produced by the oscillation of oscillatory elements excited by an energy input such as acoustic energy. An acoustofluidic apparatus includes an oscillatory energy field generator in energetic contact with one or more oscillatory elements contained in a fluid passage. Oscillation of the oscillatory elements induces microstreaming in a fluid that can be used to mix laminar flows of differing fluids, as a micropump for the directional movement of fluid through a fluid passage, for the generation of waveforms in a fluid or plurality of fluids or for other purposes.
摘要翻译：提供了一种声学流体装置，其通过在由诸如声能之类的能量输入激发的振荡元件的振荡产生的流体中产生微流体而发挥功能。声流控装置包括与容纳在流体通道中的一个或多个振荡元件能量接触的振荡能量场发生器。振荡元件的振荡在可用于混合不同流体的层流的流体中引起微流化，作为用于流体通过流体通道的定向移动的微型泵，用于在流体或多种流体中产生波形或用于其他目的。

10. 发明申请

WO2015038891A3 FUNCTIONAL PEPTIDE ANALOGS OF PEDF 审中-公开
标题翻译： PEDF的功能肽模拟
公开(公告)号：WO2015038891A3
公开(公告)日：2015-06-04
申请号：PCT/US2014055391
申请日：2014-09-12
申请人： PENN STATE RES FOUND
发明人： TOMBRAN-TINK JOYCE , BARNSTABLE COLIN J
IPC分类号： A61K38/00 , A61K38/16 , A61P9/10 , A61P27/02 , C07K14/515
CPC分类号： C07K14/8121 , A61K9/0048 , A61K38/00 , A61K38/55 , C07K7/08 , C07K16/38 , C07K2317/76 , G01N33/5008 , G01N33/5023
摘要： The invention provides compositions and methods relating to bioactive peptide analogs of PEDF.
摘要翻译：本发明提供了与PEDF的生物活性肽类似物相关的组合物和方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式