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1. 发明申请

WO2010119069A1 SELECTIVE ION TRANSPORT DEVICE 审中-公开
标题翻译：选择性运输设备
公开(公告)号：WO2010119069A1
公开(公告)日：2010-10-21
申请号：PCT/EP2010/054899
申请日：2010-04-14
申请人： OBOE IPR AB , TYBRANDT, Klas , BERGGREN, Magnus
发明人： TYBRANDT, Klas , BERGGREN, Magnus
IPC分类号： H01L51/05 , G01N33/487
CPC分类号： G01N27/447 , G01N33/48707 , H01L51/05 , H01L51/10
摘要： A device for controlled transport of ions is provided comprising an ion source element (100a) and an ion target element (100b) both conducting ions of a first class e.g. cations, and an ion selective element (101) which conducts ions of a second class e.g. anions. The device further comprises a transport element (102), which receives ions from the ion source element and releases them to the ion target element in response to an electrochemical potential difference provided across the ion transport element. In use a first electrochemical potential is applied to the control element (101), which increases the concentration of ions of said second class, which increased concentration in turn increases the ion transport rate of ions of said first class in the ion transport element (102).
摘要翻译：提供了用于离子的受控输送的装置，其包括离子源元件（100a）和离子目标元件（100b），所述离子源元件和离子目标元件（100b）阳离子和离子选择元素（101），其传导第二级的离子，例如阴离子。该装置还包括传输元件（102），其响应于跨越离子传输元件提供的电化学电势差，从离子源元件接收离子并将其释放到离子目标元件。在使用中，向控制元件（101）施加第一电化学电位，这增加了所述第二类的离子浓度，这增加了浓度，从而增加离子迁移元件（102）中所述第一类离子的离子传输速率）。

2. 发明申请

WO2010072257A1 METHOD, DEVICE AND SYSTEM TO CONTROL ADHESION, GROWTH AND/OR BIOFILM FORMATION OF PROKARYOTIC CELLS 审中-公开
标题翻译：控制粘附，生长和/或生物体形成原核细胞的方法，装置和系统
公开(公告)号：WO2010072257A1
公开(公告)日：2010-07-01
申请号：PCT/EP2008/068217
申请日：2008-12-23
申请人： OBOE IPR AB , RICHTER-DAHLFORS, Agneta , SVENNERSTEN, Karl , BERGGREN, Rolf Magnus , JAGER, Edwin , PERSSON, Kristin , ABDUL, Kader
发明人： RICHTER-DAHLFORS, Agneta , SVENNERSTEN, Karl , BERGGREN, Rolf Magnus , JAGER, Edwin , PERSSON, Kristin , ABDUL, Kader
IPC分类号： C12N11/14 , C12N13/00 , C12M1/42
CPC分类号： C12N13/00 , C08G61/126 , C08L65/00 , C12M23/20 , C12M25/08 , C12N11/14
摘要： A method to control adhesion, growth and/or biofilm formation of prokaryotic cells on a cell interaction surface of an electrochemically active element comprises bringing a medium comp rising prokaryotic cells into direct contact with the cell interaction surface, and providing an activation potential to the electrochemically active element.
摘要翻译：控制电化学活性元件的细胞相互作用表面上的原核细胞的粘附，生长和/或生物膜形成的方法包括使培养基将升高的原核细胞与细胞相互作用表面直接接触，并且向电化学提供活化电位活性元素

3. 发明申请

WO2017157729A1 ION CONDUCTIVE DEVICE WITH CONTROLLED DELIVERY ELECTRODE 审中-公开
标题翻译：带控制输送电极的离子导电装置
公开(公告)号：WO2017157729A1
公开(公告)日：2017-09-21
申请号：PCT/EP2017/055385
申请日：2017-03-08
申请人： OBOE IPR AB
发明人： JONSSON, Amanda , ARBRING SJÖSTRÖM, Theresia , SIMON, Daniel , BERGGREN, Magnus
IPC分类号： A61M5/142 , F04B19/00 , F04B43/04 , H01J37/08 , G01N33/487
CPC分类号： A61N1/306 , A61M5/14276 , A61M2205/04 , A61N1/08 , G01N33/48728
摘要： A device (100) comprising a first electrode (104) provided at or in a source electrolyte (101), and at least one ion conductive channel (103), wherein said first electrolyte (101) is arranged at a first portion (201) of the ion conductive channel (103), and a second electrode (105) provided in a target electrolyte (102), wherein said target electrolyte (102) is arranged at a second portion (202) of the ion conductive channel (103), and wherein said first and second electrodes provides an electrical control of anion flow through the ion conductive channel (103), wherein the device further comprises at least one controlled delivery electrode (114) arranged adjacent to or in the second portion of the ion conductive channel (103), wherein said first and second electrodes further are arranged to provide an electrical control of anion flow through the controlled delivery electrode (114) to the target electrolyte (102), and wherein said controlled delivery electrode (114) is adapted to deliver ions from said ion conductive channel (103) to said target electrolyte (102), and wherein said controlled delivery electrode (114) comprising an electronically and ionically conductive material (107) and an electrical contact (106), wherein said controlled delivery electrode (114) is arranged in ionic contact with, and between, said ion conductive channel (103) and the target electrolyte(102), wherein said electrical contact (106) provides for an electrical control potential (V CDE ) over the controlled delivery electrode (114) to control an ion flow between the controlled delivery electrode (114) and the target electrolyte (102).
摘要翻译：一种装置（100），包括设置在源电解质（101）处或源电解质（101）处或其中的第一电极（104）和至少一个离子传导通道（103），其中所述第一电解质（102）布置在所述离子传导沟道（103）的第一部分（201）处，以及设置在目标电解质（102）中的第二电极（105），其中所述目标电解质（102）离子传导通道（103），并且其中所述第一和第二电极提供通过离子传导通道（103）的阴离子流的电控制，其中所述装置还包括至少一个受控传送电极（114）离子传导通道（103）的第二部分，其中所述第一和第二电极进一步被布置成提供通过受控递送电极（114）到达目标电解质（102）的阴离子流的电控制，并且其中所述受控递送电极（114）是ada 以将离子从所述离子传导通道（103）传送到所述目标电解质（102），并且其中所述受控传送电极（114）包括电子和离子传导材料（107）和电触点（106），其中所述受控传送电极输送电极（114）布置成与所述离子传导通道（103）和所述目标电解质（102）离子接触并且位于所述离子传导通道（103）和所述目标电解质（102）之间，其中所述电接触（106）提供电控制电位（V CDE）（114），以控制受控输送电极（114）和目标电解质（102）之间的离子流。

4. 发明申请

WO2009115103A1 ELECTRICALLY CONTROLLED ION TRANSPORT DEVICE 审中-公开
标题翻译：电控离子传输装置
公开(公告)号：WO2009115103A1
公开(公告)日：2009-09-24
申请号：PCT/EP2008/002288
申请日：2008-03-20
申请人： OBOE IPR AB , BERGGREN, Rolf, Magnus , ISAKSSON, Joakim , JAGER, Edwin , KJÄLL, Peter , NILSSON, David , RICHTER-DAHLFORS, Agneta , SIMON, Daniel, T. , TYBRANDT, Klas , CANLON, Barbara
发明人： BERGGREN, Rolf, Magnus , ISAKSSON, Joakim , JAGER, Edwin , KJÄLL, Peter , NILSSON, David , RICHTER-DAHLFORS, Agneta , SIMON, Daniel, T. , TYBRANDT, Klas , CANLON, Barbara
IPC分类号： A61N1/30
CPC分类号： A61N1/306
摘要： A device for electrically controlled of ions, comprises a first electrolyte; a first electrode, which is arranged in direct or indirect contact with the first electrolyte, an encapsulation; and an ion conductor, which is arranged to receive and/or deliver ions from/to the first electrolyte. The encapsulation is arranged to effectively enclose the first electrolyte, and the ion conductor is arranged to transport ions from/to an outside of the encapsulation.
摘要翻译：一种用于电控离子的装置，包括第一电解质; 布置成与第一电解质直接或间接接触的第一电极，封装; 以及离子导体，该离子导体布置成从/向第一电解质接收和/或传递离子。封装被布置为有效地封闭第一电解质，并且离子导体被布置为将离子传送到封装的外部/传输到封装的外部。

5. 发明申请

WO2011124253A3 A DEVICE COMPRISING A CONDUCTIVE SURFACE AND A CONDUCTIVE POLYMER FOR ADHESION OF CELLS AND TISSUE 审中-公开
标题翻译：包含导电表面的装置和用于粘附细胞和组织的导电聚合物
公开(公告)号：WO2011124253A3
公开(公告)日：2012-05-18
申请号：PCT/EP2010054545
申请日：2010-04-06
申请人： OBOE IPR AB , PERSSON KRISTIN , KARLSSON ROGER , BERGGREN MAGNUS , KONRADSSON PETER , JAGER EDWIN , RICHTER-DAHLFORS AGNETA , SVENNERSTEN KARL
发明人： PERSSON KRISTIN , KARLSSON ROGER , BERGGREN MAGNUS , KONRADSSON PETER , JAGER EDWIN , RICHTER-DAHLFORS AGNETA , SVENNERSTEN KARL
IPC分类号： C12N11/14 , H01M10/14
CPC分类号： C12N13/00 , C08G61/126 , C08G2261/1424 , C08G2261/1452 , C08G2261/3223
摘要： The present disclosure relates to a device comprising a conductive substrate surface (19), at least one layer of a conductive polymer (14) deposited on the surface (19), a first electrolyte (13) arranged in contact with the conductive polymer layer, and a counter electrode (11), arranged in contact with the first electrolyte (13), such that a potential difference can be applied between the conductive substrate (15) and the counter electrode (11). The conductive polymer (14), in a first state, before applying the potential difference, exhibits a first adhesive capacity, wherein the conductive polymer layer (14) is substantially attached to the conductive substrate surface (19). In a second state, subsequent to application of the potential difference, the conductive polymer (14), exhibits a second adhesive capacity, such that at least a portion of the conductive polymer layer (14) is substantially released from the conductive substrate surface (19).
摘要翻译：本公开涉及包括导电基底表面（19），沉积在表面（19）上的至少一层导电聚合物（14），与导电聚合物层接触地布置的第一电解质（13））的器件，以及与所述第一电解质（13）接触地配置的对置电极（11），使得能够在所述导电性基板（15）与所述对置电极（11）之间施加电位差。在施加电位差之前，导电聚合物（14）处于第一状态，呈现出第一粘合能力，其中导电聚合物层（14）基本上附着到导电基底表面（19）上。在第二状态下，在施加电位差之后，导电聚合物（14）表现出第二粘合能力，使得导电聚合物层（14）的至少一部分基本上从导电基底表面（19）释放）。

6. 发明申请

WO2010118754A1 SELECTIVE ION TRANSPORT DEVICE 审中-公开
标题翻译：选择性运输设备
公开(公告)号：WO2010118754A1
公开(公告)日：2010-10-21
申请号：PCT/EP2009/002723
申请日：2009-04-14
申请人： OBOE IPR AB , TYBRANDT, Klas , BERGGREN, Magnus
发明人： TYBRANDT, Klas , BERGGREN, Magnus
IPC分类号： H01L51/05 , G01N33/487
CPC分类号： G01N27/447 , G01N33/48707 , H01L51/05 , H01L51/10
摘要： A device for controlled transport of ions is provided comprising an ion source element (100a) and an ion target element (100b) both conducting ions of a first class e.g. cations, and an ion selective element (101) which conducts ions of a second class e.g. anions, the device further comprises a transport element (102), which received ions from the ion source element and releases them to the ion target element in response to an electrochemical potential difference provided across the ion transport element. In use a first electrochemical potential is applied to the control element (101), which increases the concentration of ions of said second class, which increased concentration in turn increases the ion transport rate of ion of said first class in the ion transport element (102).
摘要翻译：提供了用于离子的受控输送的装置，其包括离子源元件（100a）和离子目标元件（100b），所述离子源元件和离子目标元件（100b）阳离子和离子选择元素（101），其传导第二级的离子，例如阴离子，该装置还包括传输元件（102），其响应于横跨离子传输元件提供的电化学电势差，从离子源元件接收离子并将其释放到离子目标元件。在使用中，向控制元件（101）施加第一电化学电位，其增加了所述第二类的离子浓度，这增加了浓度，从而增加了离子迁移元件（102）中所述第一类离子的离子传输速率）。

7. 发明申请

WO2009072952A1 ELECTRICALLY CONTROLLED ION TRANSPORT DEVICE 审中-公开
标题翻译：电子控制离子传输装置
公开(公告)号：WO2009072952A1
公开(公告)日：2009-06-11
申请号：PCT/SE2008/000682
申请日：2008-12-03
申请人： OBOE IPR AB , BERGGREN, Rolf, Magnus , ISAKSSON, Joakim , JAGER, Edwin , KJÄLL, Peter , NILSSON, David , RICHTER-DAHLFORS, Agneta , SIMON, Daniel, T. , TYBRANDT, Klas
发明人： BERGGREN, Rolf, Magnus , ISAKSSON, Joakim , JAGER, Edwin , KJÄLL, Peter , NILSSON, David , RICHTER-DAHLFORS, Agneta , SIMON, Daniel, T. , TYBRANDT, Klas
IPC分类号： G01N33/487
CPC分类号： G01N33/48728
摘要： The present invention relates to devices for electrically controlled transport of ions between a source and a target electrolyte, comprising: a first source electrode (101) and a first target electrode (104), each capable of conducting ions and electrons, wherein said source electrode is arranged to receive ions from said source electrolyte (102) and said target electrode is arranged to release ions to said target electrolyte (105), and means for retaining one of said source and target electrolytes on the device, which means are arranged such that each electrolyte is in contact with one of said electrodes, and a first ion-conductive channel (103), arranged to receive ions from said source electrode, to release ions to said target electrode and to provide an ionic connection between said source and said target electrodes, wherein said electrodes (101, 104) and said ion-conductive channel are formed of solid or semi-solid materials which are directly or indirectly attached to a support (107), further comprising means for limiting an electronic current between said source and said target electrodes, such that at least after a voltage is applied across said channel a potential difference between said source and target electrodes is maintained, which effects ion transport from said source to said target electrode. The present invention further relates to arrangements of and methods using such devices.
摘要翻译：本发明涉及用于在源极和目标电解质之间电离转移离子的装置，包括：第一源电极（101）和第一靶电极（104），每个能够传导离子和电子，其中所述源电极被布置成从所述源电解质（102）接收离子，并且所述目标电极被布置成将离子释放到所述目标电解质（105），以及用于将所述源电极和目标电解质中的一种保持在所述器件上的装置，每个电解质与所述电极中的一个接触，并且布置成接收来自所述源电极的离子的第一离子传导通道（103）将离子释放到所述目标电极并提供所述源和所述靶之间的离子连接电极，其中所述电极（101,104）和所述离子传导通道由固体或半固体材料形成，所述材料直接或间接附着到支撑体（ 107），还包括用于限制所述源极和所述目标电极之间的电子电流的装置，使得至少在跨所述通道施加电压之后，维持所述源电极和目标电极之间的电位差，这影响从所述源极到所述靶电极。本发明还涉及使用这种装置的方式和方法。

8. 发明申请

WO2018042046A1 ION PUMP WITH HYPERBRANCHED POLYMERS 审中-公开
标题翻译：带有超支化聚合物的离子泵
公开(公告)号：WO2018042046A1
公开(公告)日：2018-03-08
申请号：PCT/EP2017/072169
申请日：2017-09-05
申请人： OBOE IPR AB
发明人： GABRIELSSON, Roger , SANDBERG, Mats , BERGGREN, Magnus , SIMON, Daniel , POXSON, David J. , ABRAHAMSSON, Tobias Freddie
IPC分类号： C08G83/00 , G01N33/487
CPC分类号： A61N1/0444 , C08G83/005 , C08G83/006 , C08J3/24 , C08J3/28 , C08J5/2268 , C08J2300/202
摘要： A device for transport of ions and/or charged molecules between a source and a target electrolyte, comprising: a first electrode provided at or in said source electrolyte, and a second electrode provided at or in said target electrolyte; and wherein said first and second electrodes provides an electrical control of an ion flow, and further comprising means for limiting an electronic current between said source and said target electrodes, such that at least after a voltage is applied a potential difference between said source and target electrodes is maintained, which effects ion transport from said source to said target electrode; wherein the device further comprises an ion- and/or permselective polyelectrolyte for transport ions and/or charged molecules via electrophoresis and functions as an ion-selective membrane; and wherein said polyelectrolyte comprises a cross-linked hyperbranched polymer.
摘要翻译：用于在源电解质和目标电解质之间输送离子和/或带电分子的装置，包括：设置在所述源电解质处或其中的第一电极，以及设置在所述目标处或所述目标处的第二电极电解质; 并且其中所述第一和第二电极提供离子流的电控制，并且还包括用于限制所述源和所述目标电极之间的电子电流的装置，使得至少在施加电压之后，所述源和目标之间的电位差保持电极，其实现从所述源到所述目标电极的离子传输; 其中所述装置进一步包含用于通过电泳转运离子和/或带电分子的离子和/或选择性聚电解质，并用作离子选择性膜; 并且其中所述聚电解质包含交联超支化聚合物。

9. 发明申请

WO2011102789A1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES 审中-公开
标题翻译：作为分子探针的二氢胆碱衍生物
公开(公告)号：WO2011102789A1
公开(公告)日：2011-08-25
申请号：PCT/SE2011/050164
申请日：2011-02-15
申请人： OBOE IPR AB , HERMANSSON, Ola , KONRADSSON, Peter , ÅSLUND, Andreas , ILKHANIZADEH, Shirin , SIMON, Rozalyn , NILSSON, Peter
发明人： HERMANSSON, Ola , KONRADSSON, Peter , ÅSLUND, Andreas , ILKHANIZADEH, Shirin , SIMON, Rozalyn , NILSSON, Peter
IPC分类号： C07D409/14 , A61K49/00 , C12N5/0797 , G01N33/48
CPC分类号： C07D409/14 , A61K49/0021 , A61K49/006
摘要： The present invention relates to oligothiophene derivatives binding specifically to neural stem cells and neural cancer stem cells. More specifically, the invention relates to methods for detecting neural stem cells or neural cancer stem cells using said oligothiophene derivatives in a biological sample, as well as uses and kits relating thereto.
摘要翻译：本发明涉及特异性结合神经干细胞和神经癌干细胞的寡聚噻吩衍生物。更具体地，本发明涉及使用生物样品中的所述低聚噻吩衍生物检测神经干细胞或神经癌干细胞的方法，以及与之相关的用途和试剂盒。

10. 发明申请

WO2009115103A9 ELECTRICALLY CONTROLLED ION TRANSPORT DEVICE 审中-公开
标题翻译：电子控制离子传输装置
公开(公告)号：WO2009115103A9
公开(公告)日：2009-12-30
申请号：PCT/EP2008002288
申请日：2008-03-20
申请人： OBOE IPR AB , BERGGREN ROLF MAGNUS , ISAKSSON JOAKIM , JAGER EDWIN , KJAELL PETER , NILSSON DAVID , RICHTER-DAHLFORS AGNETA , SIMON DANIEL T , TYBRANDT KLAS , CANLON BARBARA
发明人： BERGGREN ROLF MAGNUS , ISAKSSON JOAKIM , JAGER EDWIN , KJAELL PETER , NILSSON DAVID , RICHTER-DAHLFORS AGNETA , SIMON DANIEL T , TYBRANDT KLAS , CANLON BARBARA
IPC分类号： A61N1/30
CPC分类号： A61N1/306
摘要： A device for electrically controlled of ions, comprises a first electrolyte; a first electrode, which is arranged in direct or indirect contact with the first electrolyte, an encapsulation; and an ion conductor, which is arranged to receive and/or deliver ions from/to the first electrolyte. The encapsulation is arranged to effectively enclose the first electrolyte, and the ion conductor is arranged to transport ions from/to an outside of the encapsulation.
摘要翻译：一种用于电离电离的装置，包括第一电解质; 布置成与第一电解质直接或间接接触的第一电极，封装; 以及离子导体，其布置成从第一电解质接收和/或递送离子。布置该封装以有效地包围第一电解质，并且离子导体被布置成将离子从封装的外部输送到外部。

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