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1. 发明授权

US4199560A Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility 失效
标题翻译：固体口服药物具有增加的疗效和预定的稳定状态的溶解度
公开(公告)号：US4199560A
公开(公告)日：1980-04-22
申请号：US952932
申请日：1978-10-19
申请人： Laszlo Gyarmati , Istvan Racz , Peter Szentmiklosi , Janos Plachy
发明人： Laszlo Gyarmati , Istvan Racz , Peter Szentmiklosi , Janos Plachy
IPC分类号： A61K9/16 , A61K9/20 , A61K9/22 , A61K9/48 , A61K9/26 , A61K9/54 , A61K33/06
CPC分类号： A61K9/1652 , A61K9/1617 , A61K9/2077 , A61K9/4841
摘要： The present invention relates to a solid oral pharmaceutical preparation with protracted release of the active ingredient consisting of discrete solid granules containing the active ingredient soluble in the stomach and auxiliary agents and of an equally solid external phase surrounding the said granules, whereby the granules forming the internal phase consist of granules prepared from a powder mixture which contains as active ingredient, or in addition to it a non-toxic metal compound, being capable of binding an acid, and being insoluble or but slightly soluble in neutral aqueous medium--particularly bismuth, aluminium or magnesium compound--and auxiliary materials prepared with an aqueous emulsion containing a hydrophobic component and hydrophylic emulsifiers, and the external phase contains a solid, dry, amphoteric gel forming substance in an amount of 1-50 percent w/w related to the total weight of the preparation in admixture with auxiliary agents.The preparation is produced by the wetting of the powder mixture containing the basic metal compound, auxiliary material and in given case additional active ingredient with the aqueous emulsion of the hydrophobic component prepared by applying the hydrophylic emulsifiers then by granulation and admixing the dried granules with the amphoteric gel forming substance, and pressing it into tablets, or filling into capsules.
摘要翻译：本发明涉及具有长时间释放的活性成分的固体口服药物制剂，其由分散的固体颗粒组成，所述固体颗粒含有可溶于胃的活性成分和辅助剂以及围绕所述颗粒的同样固体的外部相，其中颗粒形成内相包含由粉末混合物制成的颗粒，所述粉末混合物含有作为活性成分的粉末混合物，或除此之外，还含有无毒金属化合物，其能够结合酸，并且在中性水性介质（特别是铋）中不溶或略微溶解，铝或镁化合物以及用含有疏水组分和亲水乳化剂的水性乳液制备的辅助材料，并且外相含有与总量相关的1-50％w / w的固体，干燥，两性凝胶形成物质制剂的重量与助剂混合。该制备是通过润湿包含碱性金属化合物，辅助材料的粉末混合物，并且在给定情况下，通过施用亲水性乳化剂制备疏水组分的水性乳液，然后通过造粒和将干燥颗粒与两性凝胶形成物质，并将其压制成片剂或填充到胶囊中。

2. 发明授权

US4006596A Cooling-water supply system with self-adjusting hydraulics 失效
标题翻译：具有自调节液压系统的冷却水供应系统
公开(公告)号：US4006596A
公开(公告)日：1977-02-08
申请号：US642193
申请日：1975-12-18
申请人： Sandor Mikolics , Karoly Ziegler , Viktor Homola
发明人： Sandor Mikolics , Karoly Ziegler , Viktor Homola
IPC分类号： F01K9/00 , F28B11/00 , G05D23/185
CPC分类号： F28B11/00 , F01K9/003 , F28B9/04 , G05D23/185 , Y10T137/86139
摘要： Cooling water is supplied to a load, e.g. a thermal-power station, from a source of water such as a lake or stream susceptible to changes in level. The system comprises a first pump drawing water from the source, a filter arrangement downstream of the first pump, a duct downstream of the filter arrangement and a second pump connected between the duct and the input side of the load. The downstream side of the load, from which the warm water emerges, is passed through a second duct and then preferably through a warm-water level control arrangement before being disposed in a sink or other basin. A connection between the discharge duct and the feed duct is permanently maintained and allows water to flow from the feed duct to the discharge duct or vice versa in dependence upon the relative quantities of liquid displaced by the pump. As a result, the water fed through the second pump can have its temperature adjusted by mixing with warm water automatically.
摘要翻译：冷却水被供给到负载，例如一个热电站，从一个水源，如湖泊或水流易变化的水平。该系统包括从源头抽取水的第一泵，在第一泵下游的过滤器装置，过滤装置下游的管道和连接在管道和负载的输入侧之间的第二泵。负载的下游侧，其中出现温水，通过第二管道，然后优选地通过温水位控制装置，然后将其放置在水槽或其它盆中。排放管道和进料管道之间的连接被永久地保持，并且根据由泵移动的液体的相对量，允许水从进料管道流到排放管道，反之亦然。结果，通过第二泵供水的水可以通过与温水自动混合来调节其温度。

3. 发明授权

US3961895A Process and equipment for the determination of certain components, particularly the carbon dioxide content of gas mixture 失效
标题翻译：测定某些成分的工艺和设备，特别是气体混合物的二氧化碳含量
公开(公告)号：US3961895A
公开(公告)日：1976-06-08
申请号：US559044
申请日：1975-03-17
申请人： Vilmos Frenyo
发明人： Vilmos Frenyo
IPC分类号： G01N27/04 , G01N27/00 , G01N27/02 , G01N27/06 , G01N31/06
CPC分类号： G01N27/021 , Y10T436/204998
摘要： A component of a gaseous mixture, particularly carbon dioxide, can be measured in extremely small quantities or concentrations, by supporting on a solid surface a thin film of a liquid, e.g. an aqueous solution of barium hydroxide, which reacts with the gaseous component so as substantially to alter the electrical resistance of the solution. The electric resistance of the film is measured between electrodes, before and after exposure to the test gas. The test is much more sensitive than if a confined body of liquid were used as the test solution.
摘要翻译：气态混合物，特别是二氧化碳的组分可以以非常小的量或浓度测量，通过在固体表面上支撑液体的薄膜，例如，氢氧化钡的水溶液，其与气体组分反应，以便基本上改变溶液的电阻。在暴露于试验气体之前和之后，在电极之间测量膜的电阻。该测试比使用限定体积的液体作为测试溶液更敏感。

4. 发明授权

US4252556A Method of increasing plant yield with soil conditioners 失效
标题翻译：用土壤调理剂提高植物产量的方法
公开(公告)号：US4252556A
公开(公告)日：1981-02-24
申请号：US49332
申请日：1979-06-18
申请人： Miklos Nadasy , Miklos Kovacs , Marton Kolcsei , Janos Vad , Bela Bartha , Otto Dobozy , Ferenc Mate , Eva Karacsonyi nee Spindler
发明人： Miklos Nadasy , Miklos Kovacs , Marton Kolcsei , Janos Vad , Bela Bartha , Otto Dobozy , Ferenc Mate , Eva Karacsonyi nee Spindler
IPC分类号： A01N37/18 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/42 , A01N37/44 , A01N43/50 , A01N51/00 , C07D213/20 , C07D233/08 , A01N43/40 , A01N43/84
CPC分类号： C07D213/20 , A01N37/18 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/42 , A01N37/44 , A01N43/50 , A01N51/00 , C07D233/08
摘要： A cationactive soil-conditioning composition which comprises one or more active ingredients having the formulae ##STR1## wherein R is a C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl group; R.sub.1 is hydrogen, R.sub.2 is hydrogen, C.sub.2-18 as a linear or branched alkyl, alkenyl, alk-dienyl or C.sub.2-18 -alpha-keto-group, R.sub.3 is a hydrogen; R.sub.3 ' if present is hydrogen or C.sub.1-8 alkyl; X and X' are formiate, acetate, propionate, hydrophosphate, hydroxyl, halogenide or nitrate; R.sub.4 methylene, ethylene, or a polyglycol ether-group; m is a cardinal number from 1-6 and n is an integer from 1-6; R' is C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl; R.sub.5, R.sub.6, R.sub.7 if present, is a hydrogen or taken together two substituents therefrom a CH.dbd.CH--CH.dbd.CH-- group; R.sub.8, F.sub.9, if present, hydrogen or methyl; Y.sub.1 is a --CH.dbd. or oxygen; Y.sub.2 is --NH-- or oxygen; X" is halogenide, acetate, nitrate, sebacate, tartarate, propionate, phosphate, hydrogenphosphate, carbonate, hydrogencarbonate or formiate; m' is a cardinal number from 1-6; m' is an integer from 1-6; R.sub.10 and R.sub.11 are independently from each other hydrogen, ethyl, propyl, oxyethyl, oxypropyl, aminoethyl or aminopropyl-groups; R" is C.sub.9-24 linear or branched alkyl or alkenyl; X'" is nitrate, halogenide, formiate acetate, propionate or butyrate.There is also provided a process for improving the crop-bearing characteristics of soil, in which a composition containing the above active ingredient, is added to soil.
摘要翻译：一种阳离子活性土壤调理组合物，其包含一种或多种具有式（I）或（II）或（III）或（III）的活性成分，其中R是直链或支链的C 10-24烷基，或烷二烯基; R 1为氢，R 2为氢，C2-18为直链或支链烷基，链烯基，二烯基或C2-18-α-酮基，R3为氢; 如果存在R 3'是氢或C 1-8烷基; X和X'是甲酸酯，乙酸酯，丙酸酯，氢磷酸酯，羟基，卤化物或硝酸盐; R4亚甲基，亚乙基或聚乙二醇醚基; m是1-6的基数，n是1-6的整数; R'是C 10-24直链或支链烷基，烯基或烷基 - 二烯基; R5，R6，R7（如果存在）是氢或两个取代基，其中CH = CH-CH = CH-基团; R8，F9，如果存在，氢或甲基; Y1是-CH =或氧; Y2是-NH-或氧; X“是卤化物，乙酸盐，硝酸盐，癸二酸盐，酒石酸盐，丙酸盐，磷酸盐，磷酸氢盐，碳酸盐，碳酸氢盐或甲酸盐; m'是1-6的基数; m'是1-6的整数; R 10和R 11彼此独立地为氢，乙基，丙基，氧乙基，氧丙基，氨基乙基或氨基丙基; R“是C9-24直链或支链烷基或链烯基; 硝酸盐，卤化物，甲酸甲酯，丙酸盐或丁酸盐。还提供了一种改善土壤的作物承载特性的方法，其中含有上述活性成分的组合物被添加到土壤中。

5. 发明授权

US3960724A Process for the separation of natural water-soluble aluminum hydrosilicate organo-complexes 失效
标题翻译：天然水溶硅酸铝有机络合物的分离方法
公开(公告)号：US3960724A
公开(公告)日：1976-06-01
申请号：US472508
申请日：1974-05-22
申请人： Janos Barna
发明人： Janos Barna
IPC分类号： A01N25/10 , C02F1/52 , C02F1/68 , C09C1/40 , C09K17/14 , B01D43/00
CPC分类号： C01B33/42 , A01N25/10 , C01B33/26 , C01B33/40 , C01B33/46 , C02F1/5236 , C02F1/683 , C09C1/405 , C09K17/14 , C01P2004/61 , C01P2006/12
摘要： Peptisable natural aluminum hydrosilicate organo complexes are separated from water-insoluble organic and/or inorganic mineral materials and from natural aluminum hydrosilicate organo complexes that cannot be peptised in water, by milling mineral materials such as clay or brown coal to a size smaller than 60 microns, vigorously mechanically agitating the mixture at 60 to 120.degree. C. so as to dissociate the same to the colloidal state, during which the hydrophilic binding positions of the material are loosened by hydration, and finally separating the thus-formed peptised solution from insoluble material. The solution may be concentrated and the insoluble material itself is useful because of increased calorific value and higher specific surface area. Peptisation may be carried out in the presence of peptising agents such as ammonia-soda, Na.sub.2 CO.sub.3, NaOH, KOH, or cetyl-pyridine-chloride, in an amount up to 5% by weight.
摘要翻译：可溶性天然硅酸铝有机复合物与水不溶性有机和/或无机矿物材料以及天然硅酸铝有机复合物分离，不能通过将矿物材料如粘土或褐煤研磨至小于60微米在60〜120℃下大力机械搅拌该混合物，使其离解为胶体状态，在此期间，通过水合使材料的亲水结合位置松动，最后将由此形成的胶溶溶液与不溶物分离。溶液可以被浓缩，并且不溶性材料本身是有用的，因为增加的热值和较高的比表面积。肽化可以在高达5重量％的量的胶溶剂如氨水，Na 2 CO 3，NaOH，KOH或鲸蜡基 - 吡啶氯化物的存在下进行。

6. 发明授权

US4533470A Apparatus for treating liquids 失效
标题翻译：液体处理装置
公开(公告)号：US4533470A
公开(公告)日：1985-08-06
申请号：US355542
申请日：1982-03-01
申请人： Imre Gyulavari
发明人： Imre Gyulavari
IPC分类号： C02F3/14 , B01D21/00 , C02F3/12 , C02F3/20 , C02F3/16 , C02F3/18
CPC分类号： C02F3/1257 , B01D21/003 , B01D21/0045 , B01D21/02 , B01D21/24 , B01D21/2466 , B01D21/2488 , C02F3/12 , C02F3/20 , B01D2221/02 , Y02W10/15 , Y10S210/926
摘要： The invention relates to an apparatus for the treatment of liquids, in particular for the biological purification of household sewage and/or industrial sewages containing organic contaminations, furtheron for the aeration and/or sedimentation of liquids. In the circular, quadratic or elongated oblong basin receiving the liquid a path recurring in itself is formed by means of one or more partition walls. For moving the liquid in a horizontal and/or horizontal and vertical direction propellers and/or rotors with a horizontal and/or vertical axle are used.For the aeration of the liquid one or more aerators with a horizontal or vertical axle and/or one or more fixed air blowers are applied.In sense of the invention one or more secondary sedimentators in a longitudinal arrangement or with a circular top-view, provided with oblique lamellae, are connected directly to the object or are assembled therewith.
摘要翻译： PCT No.PCT / HU81 / 00027 Sec。 371日期1982年3月1日 102（e）1982年3月1日PCT PCT。1981年6月30日PCT公布。出版物WO82 / 00134 日期1982年1月21日。本发明涉及用于处理液体的设备，特别是用于生物净化家用污水和/或含有机污染物的工业污水，用于液体的通气和/或沉降。在接收液体的圆形，二次或细长椭圆形盆中，本身通过一个或多个分隔壁形成一个重复的路径。为了在水平和/或水平和垂直方向上移动液体，使用具有水平和/或垂直轴的螺旋桨和/或转子。对于液体的曝气，应用具有水平或垂直轴的一个或多个曝气器和/或一个或多个固定鼓风机。在本发明的意义上，具有纵向排列或具有倾斜薄片的圆形顶视图的一个或多个二次沉降器直接连接到物体上或与其组装。

7. 发明授权

US4252555A Method of increasing plant yield with soil conditioners 失效
标题翻译：用土壤调理剂提高植物产量的方法
公开(公告)号：US4252555A
公开(公告)日：1981-02-24
申请号：US49333
申请日：1979-06-18
申请人： Miklos Nadasy , Miklos Kovacs , Marton Kolcsei , Janos Vad , Bela Bartha , Otto Dobozy , Ferenc Mate , Eva Karacsonyi nee Spindler
发明人： Miklos Nadasy , Miklos Kovacs , Marton Kolcsei , Janos Vad , Bela Bartha , Otto Dobozy , Ferenc Mate , Eva Karacsonyi nee Spindler
IPC分类号： A01N37/18 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/42 , A01N37/44 , A01N43/50 , A01N51/00 , C07D213/20 , C07D233/08
CPC分类号： C07D213/20 , A01N37/18 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/42 , A01N37/44 , A01N43/50 , A01N51/00 , C07D233/08
摘要： A cation active soil-conditioning composition which comprises one or more active ingredients having the formulae ##STR1## wherein R is a C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl group; R.sub.1 is hydrogen, R.sub.2 is hydrogen, C.sub.2-18 as a linear or branched alkyl, alkenyl, alk-dienyl or C.sub.2-18 -alpha-keto-group, R.sub.3 is a hydrogen; R.sub.3 ' if present is hydrogen or C.sub.1-8 alkyl; X and X' are formiate, acetate, propionate, hydrophosphate, hydroxyl, halogenide or nitrate; R.sub.4 methylene, ethylene or a polyglycol ether-group; m is a cardinal number from 1-6 and n is an integer from 1-6; R' is C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl; R.sub.5, R.sub.6, R.sub.7 if present, is a hydrogen or taken together two substituents therefrom a CH.dbd.CH--CH.dbd.CH-- group; R.sub.8, R.sub.9, if present, hydrogen or methyl; y.sub.1 is a --CH.dbd. or oxygen; Y.sub.2 is --NH-- or oxygen; X" is halogenide, acetate, nitrate, sebacate, tartarate, propionate, phosphate, hydrogenphosphate, carbonate, hydrogencarbonate or formiate; m' is a cardinal number from 1-6; m' is an integer from 1-6; R.sub.10 and R.sub.11 are independently from each other hydrogen, ethyl, propyl, oxyethyl, oxypropyl, aminoethyl or aminopropyl-groups; R" is C.sub.9-24 linear or branched alkyl or alkenyl; X'" is nitrate, halogenide, formiate acetate, propionate or butyrate.There is also provided a process for improving the crop-bearing characteristics of soil, in which a composition containing the above active ingredient, is added to soil.
摘要翻译：一种阳离子活性土壤调理组合物，其包含一种或多种具有式（I）或（II）或（III）或（III）的活性成分，其中R是C 10-24直链或支链烷基，烯基或烷基 - 二烯基; R 1为氢，R 2为氢，C2-18为直链或支链烷基，链烯基，二烯基或C2-18-α-酮基，R3为氢; 如果存在R 3'是氢或C 1-8烷基; X和X'是甲酸盐，乙酸盐，丙酸盐，氢磷酸盐，羟基，卤化物或硝酸盐; R4亚甲基，乙烯或聚乙二醇醚基; m是1-6的基数，n是1-6的整数; R'是C 10-24直链或支链烷基，烯基或烷基 - 二烯基; R5，R6，R7（如果存在）是氢或两个取代基，其中CH = CH-CH = CH-基团; R8，R9，如果存在，氢或甲基; y1是-CH =或氧; Y2是-NH-或氧; X“是卤化物，乙酸盐，硝酸盐，癸二酸盐，酒石酸盐，丙酸盐，磷酸盐，磷酸氢盐，碳酸盐，碳酸氢盐或甲酸盐; m'是1-6的基数; m'是1-6的整数; R 10和R 11彼此独立地为氢，乙基，丙基，氧乙基，氧丙基，氨基乙基或氨基丙基; R“是C9-24直链或支链烷基或链烯基; 硝酸盐，卤化物，甲酸甲酯，丙酸盐或丁酸盐。还提供了一种改善土壤的作物承载特性的方法，其中含有上述活性成分的组合物被添加到土壤中。

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