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1. 发明申请

WO2004067035A1 USE OF AVIAN ANTIBODIES 审中-公开
标题翻译：使用AVIAN抗体
公开(公告)号：WO2004067035A1
公开(公告)日：2004-08-12
申请号：PCT/SE2004/000133
申请日：2004-01-30
申请人： IMMUN SYSTEM I.M.S. AB , LARSSON, Anders , KOLLBERG, Hans
发明人： LARSSON, Anders , KOLLBERG, Hans
IPC分类号： A61K39/395
CPC分类号： C07K16/1228 , A61K2039/505 , C07K2317/11 , C07K2317/23
摘要： The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
摘要翻译：本发明涉及一种治疗和预防新生儿感染特别是肠道感染的新方法，既安全又有效。这是通过使用针对微生物（特别是针对阴沟肠杆菌）的IgY来实现的，所述细菌已经通过用抗原（微生物）超免疫鸟获得，以刺激针对这种微生物产生免疫球蛋白（IgY）。本发明还涉及含有免疫球蛋白或其片段的鸟卵的药物产品，其可与用于预防或治疗新生儿胃肠道感染的其他制剂，营养物或药物同时，分开或顺序使用。

2. 发明申请

US20060134101A1 Use of avian antibodies 审中-公开
标题翻译：使用禽类抗体
公开(公告)号：US20060134101A1
公开(公告)日：2006-06-22
申请号：US10542784
申请日：2004-01-30
申请人： Anders Larsson , Hans Kollberg
发明人： Anders Larsson , Hans Kollberg
IPC分类号： A61K39/395 , A61K9/48 , A61K9/20
CPC分类号： C07K16/1228 , A61K2039/505 , C07K2317/11 , C07K2317/23
摘要： The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
摘要翻译：本发明涉及一种治疗和预防新生儿感染特别是肠道感染的新方法，既安全又有效。这是通过使用针对微生物（特别是针对阴沟肠杆菌）的IgY来实现的，所述细菌已经通过用抗原（微生物）超免疫鸟获得，以刺激针对这种微生物产生免疫球蛋白（IgY）。本发明还涉及含有免疫球蛋白或其片段的鸟卵的药物产品，其可与用于预防或治疗新生儿胃肠道感染的其他制剂，营养物或药物同时，分开或顺序使用。

3. 发明授权

EP1589995B1 USE OF AVIAN ANTIBODIES 有权
标题翻译：使用防鸟抗体的
公开(公告)号：EP1589995B1
公开(公告)日：2007-04-18
申请号：EP04706915.8
申请日：2004-01-30
申请人： Immun System I.M.S. AB
发明人： LARSSON, Anders , KOLLBERG, Hans
IPC分类号： A61K39/395 , C07K16/02 , A61P1/12 , A61P31/00
CPC分类号： C07K16/1228 , A61K2039/505 , C07K2317/11 , C07K2317/23
摘要： The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.

4. 发明公开

EP1589995A1 USE OF AVIAN ANTIBODIES 有权
标题翻译：使用防鸟抗体的
公开(公告)号：EP1589995A1
公开(公告)日：2005-11-02
申请号：EP04706915.8
申请日：2004-01-30
申请人： Immun System I.M.S. AB
发明人： LARSSON, Anders , KOLLBERG, Hans
IPC分类号： A61K39/395 , C07K16/02 , A61P1/12 , A61P31/00
CPC分类号： C07K16/1228 , A61K2039/505 , C07K2317/11 , C07K2317/23
摘要： The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.

5. 发明授权

EP0971741B1 USE OF AVIAN ANTIBODIES 失效
标题翻译： VERWENDUNG VON VOGEL-ANTIKÖRPERN
公开(公告)号：EP0971741B1
公开(公告)日：2004-05-26
申请号：EP98911344.4
申请日：1998-03-20
申请人： Immun System I.M.S. AB
发明人： LARSSON, Anders , KOLLBERG, Hans
IPC分类号： A61K39/40 , C07K16/02
CPC分类号： C07K16/02 , A61K38/00 , C07K16/1214 , Y10S514/851
摘要： The present invention relates to use of avian antibodies and/or antigen binding fragments thereof, for the production of a drug for treatment and/or prevention of respiratory tract infections. The drug is administered through local application at the oral cavity and/or pharynx.
摘要翻译：本发明涉及禽类抗体和/或其抗原结合片段在生产用于治疗和/或预防呼吸道感染的药物中的应用。该药物通过局部应用在口腔和/或咽部施用。

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