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1. 发明专利

JP2012087151A Suspension of loteprednol etabonate and tobramycin for topical ophthalmic use 有权
标题翻译：用于局部OPHTHALMIC使用的休止OL OL E E E E E E
公开(公告)号：JP2012087151A
公开(公告)日：2012-05-10
申请号：JP2012020684
申请日：2012-02-02
申请人： Bausch & Lomb Inc , ボーシュアンドロームインコーポレイティド
发明人： KRISHNAMOORTHY RAMESH
IPC分类号： A61K31/56 , A61K9/00 , A61K9/10 , A61K31/14 , A61K31/573 , A61K31/7036 , A61K31/704 , A61K47/10 , A61K47/18 , A61K47/32 , A61K47/34 , A61P27/02 , A61P27/16 , A61P29/00 , A61P31/04
CPC分类号： A61K9/0043 , A61K9/0048 , A61K31/56 , A61K31/7036 , A61K2300/00
摘要： PROBLEM TO BE SOLVED: To provide formulations for topical use comprising antibiotics in combination with anti-inflammatory steroids for treating ophthalmic infections and attendant inflammation.SOLUTION: There are provided pharmaceutical ophthalmic formulations comprising a pH stabilizing amount of tobramycin and the soft steroid loteprednol etabonate.
摘要翻译：要解决的问题：提供用于局部使用的制剂，其包含与用于治疗眼部感染和伴随的炎症的抗炎类固醇组合的抗生素。提供了包含pH稳定量的妥布霉素和软类固醇百宝布醇酯的药物眼用制剂。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2008245665A Method and apparatus for inserting flexible membrane into eye 审中-公开
标题翻译：将柔性膜插入眼睛的方法和装置
公开(公告)号：JP2008245665A
公开(公告)日：2008-10-16
申请号：JP2006217414
申请日：2006-08-09
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： CICENAS CHRIS , CLARK GEORGE , HEYMAN THOMAS M , SHERWOOD CHARLES
IPC分类号： A61F2/16 , A61F9/007
CPC分类号： A61F2/1678 , A61F2/1675
摘要： PROBLEM TO BE SOLVED: To provide an instrument for inserting a flexible intraocular lens or other flexible membrane into an eye in a controlled state.
SOLUTION: The instrument is for inserting a lens into an eye. The lens includes an optic, a leading loop haptic 16a and a trailing loop haptic. The instrument is provided with a tubular member including a route for leading the lens into the eye, and a haptic guide 125 movable inside the route for partially straightening the leading haptic 16a in the direction of advancement of the lens 12.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于在受控状态下将柔性眼内透镜或其他柔性膜插入眼睛的仪器。
解决方案：仪器用于将镜头插入眼睛。透镜包括光学元件，前导环触觉元件16a和尾部环形触觉元件。该仪器设置有包括用于将透镜引导到眼睛中的路线的管状构件，以及可在该路线内移动的触觉引导件125，用于沿着透镜12的前进方向部分矫正引导触觉部16a。版权所有：（C）2009，JPO＆INPIT

3. 发明专利

JP2008001905A Fluorosilicone hydrogels 审中-公开
标题翻译：氟代硅氢化合物
公开(公告)号：JP2008001905A
公开(公告)日：2008-01-10
申请号：JP2007181558
申请日：2007-07-10
申请人： Bausch & Lomb Inc , ボシュアンドロムインコーポレイテッド
发明人： KUNZLER JAY F , OZARK RICHARD M
IPC分类号： C08G77/385 , C08L83/04 , A61F2/16 , C07F7/18 , C08F20/52 , C08F26/00 , C08F30/08 , C08F220/54 , C08F226/00 , C08F230/08 , C08F290/00 , C08F290/06 , C08F299/08 , C08G77/04 , C08G77/20 , C08G77/22 , C08L83/02 , G02B1/04 , G02C7/04
CPC分类号： C08G77/385 , C08F30/08 , C08G77/045 , G02B1/043 , C08L43/04
摘要： PROBLEM TO BE SOLVED: To make polysiloxane materials having proper material characteristics.
SOLUTION: New fluorosiloxane-containing monomers are disclosed. These are especially useful for preparing biomedical materials such as contact lenses. A fluorosiloxane-containing monomer wherein a hydrogen-having polar fluorinated graft bound to a terminal difluoro-substituted carbon atom, or a side group is bound to a siloxane group in the polysiloxane-containing monomer is disclosed. The fluorinated polysiloxane is dissolved in a hydrophilic comonomer in an extent not needing an additional mixing agent or a solubilizing agent.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：制备具有适当材料特性的聚硅氧烷材料。解决方案：公开了新的含氟硅氧烷的单体。这些对于制备生物医学材料如隐形眼镜是特别有用的。公开了一种含氟硅氧烷的单体，其中具有与末端二氟取代的碳原子结合的氢的极性氟化接枝或侧基与含聚硅氧烷的单体中的硅氧烷基结合。氟化聚硅氧烷以不需要另外的混合剂或增溶剂的程度溶解在亲水共聚单体中。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2013190823A High water content ophthalmic devices 审中-公开
标题翻译：高水含量眼科设备
公开(公告)号：JP2013190823A
公开(公告)日：2013-09-26
申请号：JP2013116868
申请日：2013-06-03
申请人： Bausch & Lomb Inc , ボーシュアンドロームインコーポレイティド
发明人： RICHARD I BLACKWELL JR , JOSEPH C SALAMONE , JAY FRIEDRICH KUNZLER
IPC分类号： G02C7/04 , C08F220/28 , C08F220/36 , C08F220/56 , C08F220/60 , C08F226/00
CPC分类号： G02B1/043
摘要： PROBLEM TO BE SOLVED: To provide high water content ophthalmic devices.SOLUTION: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent. The ophthalmic device has an equilibrium water content of at least about 70 wt. %, and includes an evaporative dehydration barrier layer on the surface thereof. A method for mitigating evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.
摘要翻译：要解决的问题：提供高含水量的眼科装置。解决方案：公开了一种单体混合物的聚合产物，其包含（a）主要量的非含硅氧烷的亲水单体; （b）疏水单体; 和（c）交联剂。眼科装置具有至少约70重量％的平衡含水量。％，并且在其表面上包括蒸发性脱水阻隔层。还公开了一种使用高含水量眼科装置减轻蒸发角膜脱水的方法。

5. 发明专利

JP2010083901A Quinolone carboxylic acid composition and related method of treatment 审中-公开
标题翻译：喹诺酮羧酸组合物及相关治疗方法
公开(公告)号：JP2010083901A
公开(公告)日：2010-04-15
申请号：JP2010005362
申请日：2010-01-13
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： ROY SAMIR , CHANDRASEKARAN SANTOSH KUMAR , IMAMORI KATSUMI , ASAOKA TAKEMITSU , SHIBATA AKIHIRO , TAKAHASHI MASAMI , BOWMAN LYLE M
IPC分类号： A61K31/551 , A61K9/00 , A61K9/14 , A61K31/55 , A61K31/553 , A61K31/554 , A61K47/30 , A61K47/40 , A61P27/02 , A61P31/04
CPC分类号： A61K9/0048 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/554 , Y10S514/912 , Y10S514/954 , Y10S514/964
摘要： PROBLEM TO BE SOLVED: To provide a composition having a broad antibacterial spectrum which is biologically available and excellent in absorbability.
SOLUTION: The invention provides the local-ophthalmic composition comprising a quinolone carboxylic acid derivative. In one embodiment, the composition allows sustained release of the quinolone carboxylic acid derivative. In one embodiment, the composition further comprises a carboxy group-containing polymer. In one embodiment, the carboxy group-containing polymer accounts for about 0.1-6.5 wt.% of the composition based on a total weight of the composition.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供具有生物可获得性和吸收性优异的广谱抗菌谱的组合物。解决方案：本发明提供了包含喹诺酮羧酸衍生物的局部眼用组合物。在一个实施方案中，组合物允许喹诺酮羧酸衍生物的持续释放。在一个实施方案中，组合物还包含含羧基的聚合物。在一个实施方案中，基于组合物的总重量，含羧基的聚合物占组合物的约0.1-6.5重量％。版权所有（C）2010，JPO＆INPIT

6. 发明专利

JP2008304944A Contact lens packaging solution and method for improving comfort of disposable contact lens 有权
标题翻译：接触透镜包装解决方案和改善可替换接触镜的舒适性的方法
公开(公告)号：JP2008304944A
公开(公告)日：2008-12-18
申请号：JP2008230349
申请日：2008-09-08
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： SALPEKAR ANIL , TONGE STEPHEN RONALD
IPC分类号： G02C7/04 , G02C13/00 , A61L12/08
CPC分类号： A61L12/08 , Y10S422/905
摘要： PROBLEM TO BE SOLVED: To provide a new and improved solution for packaging contact lenses, and a method for treating the contact lenses with such a solution to improve the comfort of the lenses while wearing. SOLUTION: The packaging solution contains a certain kind of non-ionic surfactant containing a poly(oxyalkylene) copolymer and having a molecular weight of 4,000 to 30,000. Such a surfactant is retained on the surface of an unused lens for a long period of time, resulting in surface modification that persists in the eye, thereby providing significant improvement in the wetting properties of a fresh contact lens used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于包装隐形眼镜的新的和改进的解决方案，以及用这种解决方案处理隐形眼镜的方法，以提高穿着时镜片的舒适度。解决方案：包装溶液含有一种含有聚（氧化烯）共聚物并具有4000至30,000分子量的非离子表面活性剂。这种表面活性剂长时间保留在未使用的镜片的表面上，导致持续存在眼睛的表面改性，从而显着提高了首次使用的新鲜隐形眼镜的润湿性能，此外镜片插入后几个小时，防止干燥，提高润滑性。版权所有（C）2009，JPO＆INPIT

7. 发明专利

JP2007313346A Device for inserting flexible intraocular lens 有权
标题翻译：用于插入灵活的内窥镜的装置
公开(公告)号：JP2007313346A
公开(公告)日：2007-12-06
申请号：JP2007194311
申请日：2007-07-26
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： FIGUEROA DENNIS ALEXANDER , NIGAM ALOK , HEYMAN THOMAS MICHAEL , OVIATT HENRY W JR
IPC分类号： A61F2/16 , A61F9/007
CPC分类号： A61F2/1678 , A61F2/167 , A61F2/1691
摘要： PROBLEM TO BE SOLVED: To provide a method of packaging an intraocular lens without the need for excess operation of the lens, being systematically uncomplicated, and/or controlling the lens enough when it is inserted into an eye.
SOLUTION: A method of packaging an intraocular lens 12 comprises inserting an intraocular lens into a passage of an inserter 10 adapted to insert the lens into an eye and shipping a container having the inserter with the lens in the passage for distribution to a surgeon for surgical use.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种包含眼内透镜的方法，而不需要透镜的过度操作，系统地不复杂，和/或当其插入眼睛时足以控制透镜。解决方案：包装眼内透镜12的方法包括将眼内透镜插入插入器10的通道中，插入器10适于将透镜插入眼睛并将具有插入器的容器与透镜一起运送在通道中以分配到外科医生用于外科手术。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2007268285A Iris pattern recognition and alignment 审中-公开
标题翻译： IRIS模式识别和对齐
公开(公告)号：JP2007268285A
公开(公告)日：2007-10-18
申请号：JP2007108754
申请日：2007-04-17
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： GROTEHUSMANN ULF , YOUSSEFI GERHARD
IPC分类号： A61B3/10 , A61F9/007 , A61B3/00 , A61B3/11 , A61B3/15 , A61B5/117 , G06K9/00
CPC分类号： G06K9/00604 , A61B3/152 , A61B5/117 , A61B5/1171
摘要： PROBLEM TO BE SOLVED: To provide a device, system, and method for aligning diagnostic and therapeutic eye images associated with the field of laser eye sight correction and laser eye surgery, and in more detail, designed to obtain more accurate operation results and more satisfaction on the part of a patient. SOLUTION: A system 50 as an apparatus for aligning diagnostic and therapeutic eye images of a patient under the absence of consistent eye parameters in a diagnostic evaluation stage or treatment stage and for obtaining the improved result from laser eye sight correction surgery is a diagnosing and therapeutic system for the laser eye surgery comprising a diagnostic portion 52 and a laser treatment portion 54. The diagnostic portion 52 is provided with a diagnostic instrument 40 and a diagnostic processor 56 having a program 58 for screening, correlating, and aligning diagnostic iris images. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于对准与激光眼睛矫正和激光眼睛手术领域相关联的诊断和治疗眼睛图像的装置，系统和方法，并且更详细地，旨在获得更准确的操作结果并且对患者的满意度更高。解决方案：作为用于在诊断评价阶段或治疗阶段中在不存在一致的眼睛参数的情况下对准患者的诊断和治疗眼睛图像以及用于从激光眼睛矫正手术获得改善的结果的装置的系统50是用于激光眼科手术的诊断和治疗系统包括诊断部分52和激光治疗部分54.诊断部分52设置有诊断仪器40和诊断处理器56，其具有用于筛选，相关和校准诊断虹膜的程序58 图片。版权所有（C）2008，JPO＆INPIT

9. 发明专利

JP2007260417A Surgical operation system for providing automatic reconfiguration function 有权
标题翻译：用于提供自动重新配置功能的手术操作系统
公开(公告)号：JP2007260417A
公开(公告)日：2007-10-11
申请号：JP2007127618
申请日：2007-05-14
申请人： Bausch & Lomb Inc , ボシュロムインコーポレイテッド
发明人： BISCH MICHAEL EVREMONDE , COCHRAN BRUCE ROBERT , EBERHARDT CHRISTOPHER MICHAEL , KNIGHT JEFFERY ALAN , RITTER JOHN ALAN
IPC分类号： A61F9/007 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/00 , A61B18/14 , A61B19/00 , A61B19/02 , A61F9/00 , A61G12/00 , A61M1/00 , G02B21/00 , G05G1/30 , G06F19/00 , G08C19/28 , H02H3/12
CPC分类号： G05G1/305 , A61B17/00 , A61B17/3201 , A61B18/00 , A61B18/14 , A61B50/10 , A61B50/13 , A61B50/15 , A61B50/20 , A61B90/30 , A61B90/36 , A61B2017/00017 , A61B2017/0003 , A61B2017/00057 , A61B2017/00154 , A61B2017/00185 , A61B2017/0019 , A61B2017/00199 , A61B2017/00221 , A61B2017/00433 , A61B2017/00482 , A61B2017/00544 , A61B2017/00973 , A61B2017/00977 , A61B2050/155 , A61B2050/185 , A61B2090/3614 , A61B2217/005 , A61B2217/007 , A61F9/00 , A61F9/00736 , A61F9/00745 , A61F9/00763 , A61G12/001 , A61M2205/12 , A61M2205/505 , A61M2205/6081 , G08C19/28 , G16H40/63 , H01H2003/008 , H01H2300/04 , H02H3/12
摘要： PROBLEM TO BE SOLVED: To provide a system to control a plurality of ophthalmology microsurgery apparatuses connected to the system which the users such as ophthalmologists use when performing surgical procedures of the ophthalmology. SOLUTION: This system includes a data communication bus and a user interface 3 connected to the data communication bus. The user interface 3 supplies information to the user and receive information which is representative of a microsurgery apparatus from the user. This system is connected to the microsurgery apparatus, and includes a surgical operation module 13 to control the microsurgery apparatus as a function of at least one of the operating parameters. The surgical operation module 13 is also connected to the data communication bus. The data communication bus provides communication of data representative of the operation parameters between the user interface 3 and the surgical operation module 13. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种系统，用于控制连接到系统的多个眼科显微外科设备，眼科医生等用户在进行眼科的外科手术时使用。解决方案：该系统包括数据通信总线和连接到数据通信总线的用户接口3。用户界面3向用户提供信息并从用户接收代表显微外科手术装置的信息。该系统连接到显微外科设备，并且包括外科手术模块13，用于根据至少一个操作参数来控制显微外科手术装置。外科手术模块13也连接到数据通信总线。数据通信总线提供表示用户界面3和外科手术模块13之间的操作参数的数据的通信。版权所有：（C）2008，JPO＆INPIT

10. 发明专利

JP2004034291A Intraocular lens tumbling treatment method using coated beads 审中-公开
公开(公告)号：JP2004034291A
公开(公告)日：2004-02-05
申请号：JP2003319040
申请日：2003-09-10
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： VALLE MOISES A , YAMADA AKIRA , ROBERT KELLER
IPC分类号： G02C7/04 , A61F2/16 , A61L27/00 , B24B9/06 , B24B13/00 , B24B31/00 , B24B31/14 , B29C37/02 , B29K83/00
CPC分类号： B24B13/0006 , B24B9/06 , B24B13/0025 , B24B31/14
摘要： PROBLEM TO BE SOLVED: To provide a treatment method suitable for removing burrs, sharp-pointed edges and/or unevenness from lenses made of relatively flexible or foldable lens materials. SOLUTION: A treatment method for removing burrs, sharp-pointed edges and/or unevenness from lenses made of flexible or foldable lens materials includes a process for coating a plurality of beads with polishing material such as cerium oxide, zirconium oxide, chromium oxide, ferrous oxide, tin oxide, titanium dioxide, yttrium oxide or kieselguhr, a process for putting coated beads into a tumbler, a process for adding at least one flexible or foldable lens into the tumbler, and a process for tumbling flexible or foldable lenses together with coated beads. COPYRIGHT: (C)2004,JPO

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