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1. 发明申请

WO2014144029A3 CLINICAL RESPONSE DATA MAPPING 审中-公开
标题翻译：临床反应数据映射
公开(公告)号：WO2014144029A3
公开(公告)日：2015-01-08
申请号：PCT/US2014028264
申请日：2014-03-14
申请人： BOSTON SCIENT NEUROMODULATION
发明人： CHEN DEAN , HOFFER BRIAN JAMES , KOTHANDARAMAN SRIDHAR , LUBENSKY DAVID ARI , LUI MUN POOK , MOFFITT MICHAEL A , VANSICKLE DENNIS ALLEN
IPC分类号： A61N1/372
CPC分类号： A61N1/36132 , A61N1/37235 , A61N1/37241 , A61N1/37247
摘要： A system and method include a processor that, based on at least a subset of stored data of clinical effects of one or more stimulations of anatomical tissue performed using electrodes of an implanted leadwire, generates and outputs at least one graphical marking representing the at least the subset of the stored data. Each of the at least one graphical marking represents a respective portion of the at least the subset of the stored data and is output in association with a respective set of values for each of at least two parameters by which one or more the stimulations were performed. The markings are plotted in a graph defined by axes corresponding to values of respective stimulation parameters. Alternative, the markings are arranged in a column of a tabular report. The markings are two-toned to provide respective information for both therapeutic and adverse side effects.
摘要翻译：系统和方法包括处理器，其基于使用植入的导线的电极执行的解剖组织的一个或多个刺激的临床效应的至少一个子集，生成并输出至少一个表示至少存储数据的子集。所述至少一个图形标记中的每一个表示存储的数据的至少子集的相应部分，并且与针对执行一个或多个刺激的至少两个参数中的每一个的相应的一组值相关联地输出。标记被绘制在由相应于各个刺激参数值的轴定义的图中。替代方案，标记排列在表格报表的列中。标记是双色的，以提供治疗和不良副作用的各种信息。

2. 发明申请

WO2014036079A3 PARAMETER VISUALIZATION, SELECTION, AND ANNOTATION INTERFACE 审中-公开
标题翻译：参数可视化，选择和说明接口
公开(公告)号：WO2014036079A3
公开(公告)日：2014-10-23
申请号：PCT/US2013056981
申请日：2013-08-28
申请人： BOSTON SCIENT NEUROMODULATION
发明人： CARCIERI STEPHEN , CHEN DEAN , MOFFITT MICHAEL A
IPC分类号： A61N1/36 , A61N1/05 , A61N1/372
CPC分类号： A61N1/37247 , A61N1/0534 , A61N1/3605 , A61N1/36082 , A61N1/36185 , A61N1/372 , G06F19/3406 , G16H40/63
摘要： According to an example, a system and method for providing a user interface by which to display and/or control stimulation parameter settings includes a processor displaying a ray at an angle from a predetermined direction, and about a point representing a leadwire, that corresponds to a direction at which an electrical field is produced by respective electrical settings of one or more directional electrodes of the leadwire, and whose ray length corresponds to an electrical amplitude of an electrical parameter of the one or more directional electrodes. According to an example, a system and method for selecting leadwire stimulation parameters includes a processor iteratively performing, for each of a plurality of values for a particular stimulation parameter, each value corresponding to a respective current field: (a) shifting the current field longitudinally and/or rotationally to a respective plurality of locations about the leadwire; and (b) for each of the respective plurality of locations, obtaining clinical effect information regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location; and displaying a graph plotting the clinical effect information against values for the particular stimulation parameter and locations about the leadwire, and/or based on the obtained clinical effect information, identifying an optimal combination of a selected value for the particular stimulation parameter and selected location about the leadwire at which to perform a stimulation using the selected value. According to an example, a system and method for outputting historical stimulation information includes a processor configured to assign individual display regions, e.g., pixels or voxels, (or a larger region) a score based on those volumes of activations (VOA) in which the individual display region had been included and the scores assigned to those VOAs, and display in a display device a map of varying graphical indicia based on the different scores assigned to the elemental display regions.
摘要翻译：根据一个示例，用于提供用于显示和/或控制刺激参数设置的用户界面的系统和方法包括处理器，其以与预定方向成一定角度显示射线，以及关于表示引线的点，其对应于通过引线的一个或多个方向电极的相应电气设置产生电场的方向，并且其射线长度对应于一个或多个定向电极的电参数的电幅度。根据一个示例，用于选择引线刺激参数的系统和方法包括处理器对于特定刺激参数的多个值中的每一个迭代地执行与相应的当前场对应的每个值：（a）纵向移动当前场和/或旋转地到围绕引线的相应多个位置; 和（b）针对相应的多个位置中的每一个，获得关于由相应位置处的相应电流场产生的患者组织的相应刺激的临床效果信息; 并且显示绘制临床效果信息与针对特定刺激参数和关于引线的位置的值的图形，和/或基于获得的临床效果信息，识别特定刺激参数的选定值和所选位置的最佳组合使用所选择的值进行刺激的引线。根据一个示例，用于输出历史刺激信息的系统和方法包括处理器，其被配置为基于那些激活量（VOA）来分配单独的显示区域，例如像素或体素（或更大的区域）分数，其中单独显示区域已被包括，分数分配给这些VOA，并且基于分配给元素显示区域的不同分数，在显示设备中显示不同图形标记的映射。

3. 发明申请

WO2013181519A3 LEADS WITH TIP ELECTRODE FOR ELECTRICAL STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 审中-公开
标题翻译：带尖端电极的引线用于电刺激系统及其制造和使用方法
公开(公告)号：WO2013181519A3
公开(公告)日：2014-03-27
申请号：PCT/US2013043588
申请日：2013-05-31
申请人： BOSTON SCIENT NEUROMODULATION
发明人： PIANCA ANNE MARGARET , HOWARD JOSHUA DALE , ORINSKI WILLIAM GEORGE
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0534 , A61N1/056 , A61N1/0565 , A61N1/3605
摘要： An implantable electrical stimulation lead includes a tip electrode disposed on a distal tip of the lead body. One tip electrode has a base and a separate plug attached to the base. The base defines an interior lumen closed at one end by the plug. Another tip electrode has an electrode body, a stem extending from the electrode body, and shaped retention features extending from the stem. Yet another tip electrode has an electrode body, a stem extending from the electrode body, and a flange disposed on the stem opposite the electrode body. A further tip electrode has an electrode body defining an interior lumen and a plurality of protrusions extending into the interior lumen. Another tip electrode has an electrode body and arms extending from the electrode body. The electrode body defines an interior lumen and the arms extend over an opening to the interior lumen.
摘要翻译：可植入电刺激引线包括设置在引线主体的远端上的尖端电极。一个尖端电极具有底座和附接到基座的单独插头。底座限定了一端通过插头封闭的内腔。另一个尖端电极具有电极体，从电极本体延伸的杆以及从杆延伸的成形保持特征。另一个尖端电极具有电极体，从电极主体延伸的杆和设置在与杆体相对的杆上的凸缘。另一个尖端电极具有限定内腔的电极体和延伸到内腔中的多个突起。另一个尖端电极具有电极体和从电极体延伸的臂。电极体限定内腔，并且臂延伸到内腔内的开口上。

4. 发明申请

WO2014014581A3 CHARGING SYSTEM WITH A BENDABLE SUPPORT FOR AN IMPLANTABLE DEVICE 审中-公开
标题翻译：具有可伸缩装置的可弯曲支撑的充电系统
公开(公告)号：WO2014014581A3
公开(公告)日：2014-03-20
申请号：PCT/US2013045114
申请日：2013-06-11
申请人： BOSTON SCIENT NEUROMODULATION
发明人： LUI MUN POOK , AGHASSIAN DANIEL
IPC分类号： A61N1/378 , H02J7/00
CPC分类号： H02J50/12 , A61N1/3787 , H02J5/005 , H02J7/0042 , H02J7/0052 , H02J7/025
摘要： An external charging system (200) for charging or powering an implantable medical device is disclosed which is self-affixing to the patient without the need for a holding device. The charging system can comprise two modules (210, 215) attached to opposite ends of a flexible member (220). The flexible member is bendable and when bent will firmly hold its position on the patient. The two modules can comprise a coil module (215) containing a charging coil and an electronics module (210) including a user interface and the necessary electronics for activating the charging coil to produce a magnetic charging field. Wires can couple the charging coil in the coil module to the electronics in the electronics module. The entire assembly can be encased in a water proof sleeve (205) having a high-friction surface, which protects the charging system and helps the charging system to adhere to the patient.
摘要翻译：公开了一种用于对可植入医疗装置进行充电或供电的外部充电系统（200），其不需要保持装置就可自行贴附到患者身上。充电系统可以包括附接到柔性构件（220）的相对端的两个模块（210,215）。柔性构件是可弯曲的，并且当弯曲时将牢固地将其位置保持在患者身上。两个模块可以包括包含充电线圈的线圈模块（215）和包括用户接口的电子模块（210）和用于激活充电线圈以产生磁性充电场的必要电子装置。电线可以将线圈模块中的充电线圈耦合到电子模块中的电子装置。整个组件可以被包装在具有高摩擦表面的防水套筒（205）中，这保护充电系统并帮助充电系统粘附到患者身上。

5. 发明申请

WO2014035733A1 SYSTEM AND METHOD FOR CONNECTING DEVICES TO A NEUROSTIMULATOR 审中-公开
标题翻译：将装置连接到神经细胞的系统和方法
公开(公告)号：WO2014035733A1
公开(公告)日：2014-03-06
申请号：PCT/US2013055884
申请日：2013-08-20
申请人： BOSTON SCIENT NEUROMODULATION
发明人： KOTHANDARAMAN SRIDHAR , LUI MUN POOK
IPC分类号： A61N1/372
CPC分类号： A61N1/36185 , A61N1/37247
摘要： A method for defining connections between a plurality of lead bodies and a plurality of output ports of a neurostimulator, and an external control device for performing the method are disclosed. The external control device includes a user interface and control circuitry. The method includes displaying the lead bodies and the output ports of the neurostimulator; selecting a first one of the lead bodies; dragging a connector from the first lead body to a first one of the output ports of the neurostimulator; and dropping the connector onto the first output port of the neurostimulator, thereby defining a connection between the first lead body and the first output port of the neurostimulator. In another embodiment, a method includes defining the connection between the first lead body and the first output port, and graphically displaying the connection between the first lead body and the first output port of the neurostimulator.
摘要翻译：公开了一种用于定义多个引线主体与神经刺激器的多个输出端口之间的连接的方法，以及用于执行该方法的外部控制装置。外部控制装置包括用户界面和控制电路。该方法包括显示神经刺激器的引导体和输出端口; 选择第一个铅体; 将连接器从第一引线体拖动到神经刺激器的输出端口中的第一个; 并将连接器放在神经刺激器的第一输出端口上，由此限定第一引线体与神经刺激器的第一输出端口之间的连接。在另一个实施例中，一种方法包括限定第一引线本体与第一输出端口之间的连接，并以图形方式显示神经刺激器的第一引线主体与第一输出端口之间的连接。

6. 发明申请

WO2012135195A3 COMMUNICATION INTERFACE FOR THERAPEUTIC STIMULATION PROVIDING SYSTEMS 审中-公开
标题翻译：用于治疗性刺激提供系统的通信接口
公开(公告)号：WO2012135195A3
公开(公告)日：2013-06-27
申请号：PCT/US2012030705
申请日：2012-03-27
申请人： BOSTON SCIENT NEUROMODULATION , SPARKS TROY , CARLTON KEITH , KOKONES SCOTT , MOFFITT MICHAEL A
发明人： SPARKS TROY , CARLTON KEITH , KOKONES SCOTT , MOFFITT MICHAEL A
IPC分类号： G06F19/00
CPC分类号： G06T7/0038 , A61B34/25 , A61N1/08 , A61N1/36128 , A61N1/37247 , F04C2270/041 , G06F3/04815 , G06F3/04845 , G06F19/321 , G06F19/3481 , G06K9/4642 , G06K9/6215 , G06K2009/4666 , G06T3/40 , G06T3/4038 , G06T7/0012 , G06T7/30 , G06T7/33 , G06T7/38 , G06T11/003 , G06T11/60 , G06T15/005 , G06T15/08 , G06T19/00 , G06T19/003 , G06T2200/04 , G06T2200/24 , G06T2207/10064 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10092 , G06T2207/30016 , G06T2219/028
摘要： A system and method for communicating patient data for therapeutic stimulation purposes may provide a communication interface for exporting patient data, a communication interface for importing patient data, and a user interface for programming a patient device in response to communication of patient data.
摘要翻译：用于传达用于治疗刺激目的的患者数据的系统和方法可以提供用于导出患者数据的通信接口，用于导入患者数据的通信接口和用于响应于患者数据的通信来编程患者设备的用户界面。

7. 发明申请

WO2012135191A3 SYSTEM AND METHOD FOR LEADWIRE LOCATION 审中-公开
标题翻译：领导地位系统与方法
公开(公告)号：WO2012135191A3
公开(公告)日：2013-06-13
申请号：PCT/US2012030701
申请日：2012-03-27
申请人： BOSTON SCIENT NEUROMODULATION , SPARKS TROY , BLUM DAVID ARTHUR , KOKONES SCOTT , CARLTON KEITH , BOKIL HEMANT SHARAD
发明人： SPARKS TROY , BLUM DAVID ARTHUR , KOKONES SCOTT , CARLTON KEITH , BOKIL HEMANT SHARAD
IPC分类号： G06F19/00
CPC分类号： G06T7/0038 , A61B34/25 , A61N1/08 , A61N1/36128 , A61N1/37247 , F04C2270/041 , G06F3/04815 , G06F3/04845 , G06F19/321 , G06F19/3481 , G06K9/4642 , G06K9/6215 , G06K2009/4666 , G06T3/40 , G06T3/4038 , G06T7/0012 , G06T7/30 , G06T7/33 , G06T7/38 , G06T11/003 , G06T11/60 , G06T15/005 , G06T15/08 , G06T19/00 , G06T19/003 , G06T2200/04 , G06T2200/24 , G06T2207/10064 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10092 , G06T2207/30016 , G06T2219/028
摘要： A system and method for leadwire location may provide for recognition of the leadwire via analysis of a series of two-dimensional images that include representations of the leadwire, and/or determining an orientation of the leadwire with reference to a marker on the leadwire.
摘要翻译：用于引线位置的系统和方法可以通过分析包括引线的表示的一系列二维图像和/或参考引线上的标记来确定引线的取向来提供对引线的识别。

8. 发明申请

WO2012166656A3 COLLECTION OF CLINICAL DATA FOR GRAPHICAL REPRESENTATION AND ANALYSIS 审中-公开
标题翻译：收集用于图形表示和分析的临床数据
公开(公告)号：WO2012166656A3
公开(公告)日：2013-04-11
申请号：PCT/US2012039709
申请日：2012-05-25
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A , REINHOLD JOHN J
发明人： MOFFITT MICHAEL A , REINHOLD JOHN J
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/37247 , A61N1/3615 , A61N1/36185 , A61N1/37235 , A61N1/37241
摘要： An external programmer for use with a neurostimulator. Electrical stimulation energy is serially conveyed into tissue of the patient via different combinations of electrodes implanted within the patient, thereby creating one or more clinical effects for each of the different electrode combinations. An influence of each of the different electrode combinations on the clinical effect (s) is determined. A graphical indication of the one or more clinical effects is generated based on the determined electrode combination influences. A graphical representation of the electrodes is displayed. The graphical indication of the clinical effect (s) is displayed adjacent the graphical electrode representation, such that a user can view an extent to which each of the different electrode combinations influences the clinical effect (s).
摘要翻译：用于神经刺激器的外部程序员。电刺激能量通过植入患者体内的电极的不同组合被顺序地输送到患者的组织中，从而为每个不同的电极组合产生一个或多个临床效果。确定每个不同电极组合对临床效果的影响。基于确定的电极组合影响产生一种或多种临床效果的图形指示。显示电极的图形表示。临床效果的图形指示显示在图形电极表示附近，使得用户可以观察每个不同电极组合影响临床效果的程度。

9. 发明申请

WO2012003131A4 CHARGING SYSTEM FOR AN IMPLANTABLE MEDICAL DEVICE EMPLOYING MAGNETIC AND ELECTRIC FIELDS 审中-公开
标题翻译：使用磁场和电场的可植入医疗装置的充电系统
公开(公告)号：WO2012003131A4
公开(公告)日：2012-04-12
申请号：PCT/US2011041606
申请日：2011-06-23
申请人： BOSTON SCIENT NEUROMODULATION , CHEN JOEY , OZAWA ROBERT , HYUN JOONHO , DRONOV VASILY
发明人： CHEN JOEY , OZAWA ROBERT , HYUN JOONHO , DRONOV VASILY
IPC分类号： A61N1/378 , A61N1/372
CPC分类号： A61N1/37223 , A61N1/3787 , H01Q1/273 , H01Q9/42
摘要： A base station for passively recharging a battery in an implant without patient involvement is disclosed. The base station can be hand held or may comprise equipment configured to be placed at a fixed location, such as under a bed, on or next to a wall, etc. The base station can generate electric and magnetic fields (E- field and B-field) that couple with an antenna and a receiving coil within the implant to generate a charging current for charging the implant's battery. No handling or manipulation on part of the patient is necessary; the implant battery is passively charged whenever the patient is within range of either the magnetic or electric charging fields generated by base station. Charging using the B-field occurs when the IPG is at a relatively short distance from the base station, while charging using the E-field occurs at longer distances. Back telemetry from the implant can inform the base station whether B-field or E-field charging is indicated, and is preferred if possible for its ability to transfer higher amounts of power to the implant.
摘要翻译：公开了用于被动地给植入物中的电池充电而没有患者参与的基站。基站可以是手持式的，或者可以包括被配置为放置在固定位置处的设备，例如在床下面，墙上或旁边等。基站可以产生电场和磁场（E场和B场场），其与植入物内的天线和接收线圈耦合以生成用于给植入物的电池充电的充电电流。部分患者不需要操作或操作; 无论何时患者处于由基站产生的磁场或电荷场的范围内，植入物电池都被动充电。当IPG距离基站相对较短的距离时，使用B场进行充电，而使用电场进行充电的距离较远。植入物的背部遥测可以通知基站是否显示B场或电场充电，并且如果可能的话，由于其向植入物传送更大量的功率的能力，所以是优选的。

10. 发明申请

WO2012003140A3 IMPLANTABLE MEDICAL DEVICE AND CHARGING SYSTEM EMPLOYING ELECTRIC FIELDS 审中-公开
标题翻译：可植入医疗装置和使用电场的充电系统
公开(公告)号：WO2012003140A3
公开(公告)日：2012-03-29
申请号：PCT/US2011041773
申请日：2011-06-24
申请人： BOSTON SCIENT NEUROMODULATION , CHEN JOEY , OZAWA ROBERT , HYUN JOONHO , DRONOV VASILY
发明人： CHEN JOEY , OZAWA ROBERT , HYUN JOONHO , DRONOV VASILY
IPC分类号： A61N1/378 , A61N1/372 , H01Q1/00
CPC分类号： A61N1/37223 , A61N1/3787 , H01Q1/273 , H01Q9/42
摘要： An implantable medical device and external base station system are disclosed. The external base station can provide a passive electric field to power the implant, or to charge its battery. The base station may also power or charge using magnetic fields under certain circumstances. The Implantable medical device may comprise an implantable neurostimulator having a number of electrode leads extending from its body. One or more of the electrode leads can comprise the antenna for receiving the electric field from the base station, and resonance in that antenna can be rectified to provide the power for recharging the battery. Although the E-field provided by the base station does not provide as much power for recharging as does other traditional charging techniques (such as those using magnetic fields), it can occur passively and over longer distances to allow the patent's implant to be recharged when in relative proximity to the base station.
摘要翻译：公开了一种可植入医疗设备和外部基站系统。外部基站可以提供无源电场来为植入物供电或为其电池充电。在某些情况下，基站也可以使用磁场进行供电或充电。可植入医疗装置可以包括具有从其主体延伸的多个电极引线的可植入神经刺激器。一个或多个电极引线可以包括用于接收来自基站的电场的天线，并且可以对该天线中的谐振进行整流以提供用于对电池进行再充电的电力。尽管由基站提供的电场与其他传统充电技术（例如使用磁场的那些技术）不能提供充足的充电电力，但其可以被动地发生并且在更长的距离上发生，以允许专利的植入物在充电时被充电相对靠近基站。

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