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    • 4. 发明专利
    • IMPLANTABLE SCAFFOLDS FOR TREATMENT OF SINUSITIS
    • SG11201909621UA
    • 2019-11-28
    • SG11201909621U
    • 2018-04-20
    • 480 BIOMEDICAL INC
    • YOU CHANGCHENGPHAM QUYNHCONCAGH DANNY
    • A61F2/18A61F2/82A61K9/00A61K31/58A61L31/16A61M31/00
    • Title: IMPLANTABLE SCAFFOLDS FOR TREATMENT OF SINUSITIS (57) : This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis. An implant is configured to fit inside of the middle meatus of a human nasal cavity. The implant includes a therapeutic-agent formulation containing a lay- er of over 2000 micrograms of mometasone furoate. The implant releas- es the mometasone furoate for more than 12 weeks. A second implant can also be provided configured to fit inside the middle meatus. The sec- ond implant also includes a therapeutic-agent formulation containing a layer of over 2000 micrograms of mometasone furoate, and releases the mometasone furoate for more than 12 weeks. W O 20 18/ 195 48 4 Al 10 FIG. 1A 14 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 25 October 2018 (25.10.2018) WIPO I PCT omit IIl °nolo mu loom mourn° oimIE (10) International Publication Number WO 2018/195484 Al (51) International Patent Classification: A61F 2/18 (2006.01) A61K 31/58 (2006.01) A61F 2/82 (2013.01) A61L 31/16 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01) (21) International Application Number: PCT/US2018/028655 (22) International Filing Date: 20 April 2018 (20.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 15/492,103 20 April 2017 (20.04.2017) US (71) Applicant: 480 BIOMEDICAL, INC. [US/US]; 480 Ar- senal Street, Watertown, MA 02472 (US). (72) Inventors: YOU, Changcheng; 378 Moonhill Road, Northbridge, MA 01534 (US). PHAM, Quynh; 8 Tuscany Drive, Methuen, MA 01844 (US). CONCAGH, Danny; 7 Lakewood Drive, Medfield, MA 02052 (US). (74) Agent: CARROLL, Peter, G. et al.; Medlen & Carroll, LLP, 1440 Broadway, Suite 1010, Oakland, CA 94612 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))