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    • 5. 发明专利
    • Enzyme-containing composition, method for producing the same and use thereof
    • 含酶的组合物,其生产方法及其用途
    • JP2010090164A
    • 2010-04-22
    • JP2009294987
    • 2009-12-25
    • 3M Espe Agスリーエム エスペ アーゲー
    • HAEBERLEIN INGOGUGGENBERGER RAINERWEINMANN WOLFGANGKAPPLER OLIVER
    • A61K8/19A61K8/66A61K8/73A61K38/48A61P1/02A61Q11/00
    • A61K38/47A61K38/482A61K38/488A61K38/4886A61K2300/00
    • PROBLEM TO BE SOLVED: To cope with problems requiring a composition for removal of tooth tissue infected with caries by daily practice with a simple and painless method, further a composition for removal of caries without affecting, damaging or at least avoiding healthy tooth materials valuable to be preserved, and further a composition for removal of caries essentially securing no remaining of bacterial residue after treatment of caries, and further requiring a method for treating caries with simple and painless manner. SOLUTION: The composition includes at least one of each of biologically active protease and glycosidase with their activity ratio of 1,000,000:1 to 1:1,000,000 and at least 2 U/mL of the total enzymic activity. The method further relates to the method for production of the composition including such enzymes and a method of removing caries. In addition, the composition relates to use of the composition including one or more enzymes to produce a therapeutic agent for the removal of caries. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:为了解决需要通过简单和无痛方法通过日常实践去除感染龋齿的牙齿组织的组合物的问题,还提供了用于去除龋齿而不影响,损伤或至少避免健康牙齿的组合物 有待保存的材料,以及进一步用于除去龋齿的组合物,基本上确保了龋齿处理后没有残留的细菌残留物,并且还需要一种以简单且无痛的方式治疗龋齿的方法。 解决方案:组合物包含生物活性蛋白酶和糖苷酶各自中的至少一种,其活性比为1,000,000:1-1,000,000,总酶活性为至少2U / mL。 该方法还涉及包含这些酶的组合物的生产方法以及去除龋齿的方法。 此外,该组合物涉及包含一种或多种酶的组合物的使用以产生用于去除龋齿的治疗剂。 版权所有(C)2010,JPO&INPIT
    • 9. 发明专利
    • Dental adhesive composition
    • 牙膏组合物
    • JP2006089484A
    • 2006-04-06
    • JP2005276545
    • 2005-09-22
    • 3M Espe Agスリーエム イーエスピーイー アーゲー
    • THALACKER CHRISTOPHHEUMANN ANDREAS A
    • A61K6/083A61K6/08
    • A61K6/0023A61K6/0017A61K6/0835C08L33/00
    • PROBLEM TO BE SOLVED: To obtain a dental adhesive composition having optimized viscosity and/or rheological kinetics. SOLUTION: A dental composition comprises (a) at least one carboxylic acid-functional polymer, (b) at least one acid derivative substituted with at least one polymerizable ethylenically unsaturated group and having a higher acidity than that of the carboxylic acid-functional polymer (a) and (c) 0.1-10 wt.% of water. The carboxylic acid-functional polymer (a) and the acid derivative (b) are present in at least effective amounts. The dental composition exhibits shear thinning and/or 1.0-20 Pa s viscosity when measured at 0.5-1 s -1 shear rate by using a plate/plate arrangement. Furthermore, the use of the dental composition and a method for preparing a dental adhesive are provided. COPYRIGHT: (C)2006,JPO&NCIPI
    • 待解决的问题:获得具有优化的粘度和/或流变动力学的牙科粘合剂组合物。 解决方案:牙科用组合物包含(a)至少一种羧酸官能聚合物,(b)至少一种被至少一个可聚合的烯键式不饱和基团取代并具有比羧酸官能团聚合物更高的酸度的酸衍生物, 官能聚合物(a)和(c)0.1-10重量%的水。 羧酸官能聚合物(a)和酸衍生物(b)以至少有效量存在。 牙齿组合物通过使用板/板布置在0.5-1s -1剪切速率下测量时显示出剪切变稀和/或1.0-20Pa的粘度。 此外,提供牙科用组合物的使用和牙科粘合剂的制备方法。 版权所有(C)2006,JPO&NCIPI