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1. 发明专利

JP5647936B2 修飾ヌクレオチド及びこれを用いたリアルタイムポリメラーゼ反応有权
标题翻译：修饰的核苷酸和实时聚合酶反应使用相同的
公开(公告)号：JP5647936B2
公开(公告)日：2015-01-07
申请号：JP2011091737
申请日：2011-04-18
申请人：韓国科学技術研究院Korea Institute Of Science And Tecnology , 韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人：大魯安 , 大魯安
IPC分类号： C12Q1/68 , C12N15/09 , G01N21/64
CPC分类号： C07H19/20

3. 发明专利

JP2012006906A Composition containing longan arillus extract or mixed extract including this for prophylaxis or medical treatment of regressive cranial nerve disorders 有权
标题翻译：含有长链球菌提取物或混合提取物的组合物，包括用于预防或治疗复发性神经系统疾病的预防或治疗
公开(公告)号：JP2012006906A
公开(公告)日：2012-01-12
申请号：JP2010249044
申请日：2010-11-05
申请人： Korea Advanced Inst Of Sci Technol , 韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人： YANG HYUN-OK , BAE NA YOUNG , KWON HAK-CHEOL , CHUNG SUNG-KWON , OH MYUNG SOOK
IPC分类号： A61K36/18 , A23L1/30 , A61K36/00 , A61K36/23 , A61K36/48 , A61K36/53 , A61K36/70 , A61K36/71 , A61P21/00 , A61P25/00 , A61P25/16 , A61P25/28
CPC分类号： A61K36/77 , A61K36/31 , A61K36/488 , A61K36/539 , A61K2300/00
摘要： PROBLEM TO BE SOLVED: To provide a pharmaceutical composition and a food composition for the prophylaxis or the medical treatment of regressive cranial nerve disorders.SOLUTION: The pharmaceutical composition and food composition include as an effective component an extract from the longan arillus of an aril of the longan tree of Sapindaceae plant. Preferably, this pharmaceutical composition and food composition still more contain additionally one or more kind extracts selected from the group consisting of angelicae tenuissimae radix and polygalae radix, and moreover contain additionally one or more kind extracts selected from the group consisting of pueraria lobata radix, scutellariae radix, platycodi radix, angelicae dahuricae radix, cimicifugae rhizoma, raphani semen, and acori graminei rhizoma. Preferably, the regressive cranial nerves disorders are selected from the group consisting of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.
摘要翻译：要解决的问题：提供用于预防或治疗回归性颅神经障碍的药物组合物和食物组合物。解决方案：药用组合物和食品组合物包括作为有效成分的来自椴树科植物龙眼树的龙眼菌的提取物。优选地，该药物组合物和食品组合物还含有另外一种或多种提取物，其选自由当归的天竺葵和多鳃根，还含有一种或多种提取物，其选自葛根根，黄芩甘草，桔梗，当归，西葫芦，aph草精和禾本科植物。优选地，回归性颅神经障碍选自阿尔茨海默氏病，帕金森氏病，肌萎缩性侧索硬化和多发性硬化。版权所有（C）2012，JPO＆INPIT

4. 发明专利

JP4632622B2 How to adjust the T- type calcium channel suppression of visceral pain 有权
公开(公告)号：JP4632622B2
公开(公告)日：2011-02-23
申请号：JP2002310392
申请日：2002-10-25
申请人：韓国科学技術研究院
发明人：ダエスーキム , チャンキキム , ヒー−サプシン
IPC分类号： A61K31/4184 , G01N33/50 , A61K31/00 , A61K33/00 , A61K33/24 , A61K45/00 , A61P1/00 , A61P25/00 , A61P25/02 , A61P25/04 , A61P29/00 , A61P43/00 , G01N33/15 , G01N33/68
CPC分类号： A61K31/4184 , A61K31/00 , A61K33/00 , G01N33/6872 , G01N2500/04

5. 发明专利

JP2011033613A Kit and method for detecting antigen based on immunoassay 有权
标题翻译：用于基于免疫测定法检测抗原的试剂盒和方法
公开(公告)号：JP2011033613A
公开(公告)日：2011-02-17
申请号：JP2010103434
申请日：2010-04-28
申请人： Korea Advanced Inst Of Sci Technol , 韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人： AN DAIRO , YANG EUN GYEONG , HAN KI-CHEOL
IPC分类号： G01N33/543 , C12N15/09 , C12Q1/68
CPC分类号： G01N33/542 , G01N33/54306 , G01N2458/10
摘要： PROBLEM TO BE SOLVED: To provide a kit for detecting an antigen containing a capture antibody, a detecting antibody combined with a single stranded DNA oligonucleotide, a single stranded RNA oligonucleotide complementarily lined to the DNA oligonucleotide and marked with a fluorescent material, and an RNA degradative enzyme, and to provide a method of detecting the antigen using the same. SOLUTION: The DNA oligonucleotide marked with both ends marked with a fluorescent material and a fluorescence quenching matter is connected to an antibody to amplify a signal using an enzyme, and the signal amplification is performed using the increase of a fluorescent signal generated by causing an RNase H to cut an RNA using the RNA oligonucleotide and the RNase (i.e., RNase H) complementarily to the DNA oligonucleotide when the target molecule is present. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于检测含有捕获抗体的抗原的试剂盒，与单链DNA寡核苷酸组合的检测抗体，与DNA寡核苷酸互补排列并用荧光材料标记的单链RNA寡核苷酸，和RNA降解酶，并提供使用其进行抗原检测的方法。解决方案：标记有荧光材料的两端标记的DNA寡核苷酸，荧光猝灭物质与抗体连接以使用酶扩增信号，并且使用由当靶分子存在时，使RNA酶H使用RNA寡核苷酸和RNase（即RNA酶H）与DNA寡核苷酸互补切割RNA。版权所有（C）2011，JPO＆INPIT

6. 发明专利

JP4571611B2 Biosensor protein kinase a detection and a kit having the same 有权
公开(公告)号：JP4571611B2
公开(公告)日：2010-10-27
申请号：JP2006318816
申请日：2006-11-27
申请人：韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人：大成尹 , 恩卿楊 , 泰松金 , 基 ▲吉▼ 韓
IPC分类号： G01N33/573 , G01N5/02 , G01N33/483 , G01N33/543 , G01N33/551
CPC分类号： C12Q1/485 , C12Q1/001 , G01N33/54373

7. 发明专利

JP2005068547A Method of fabricating superfine cermet alloy with homogeneous solid solution grain structure 审中-公开
标题翻译：用均匀固体溶液颗粒结构制备超细晶合金的方法
公开(公告)号：JP2005068547A
公开(公告)日：2005-03-17
申请号：JP2003347486
申请日：2003-10-06
申请人： Korea Advanced Inst Of Sci Technol , 韓国科学技術研究院
发明人： SHIM JAE HYEOK , PARK JONG KU , CHO YOUNG WHAN
IPC分类号： B22F7/00 , B22F1/00 , B22F3/14 , C22C1/10 , C22C29/06 , C22C29/10
CPC分类号： B22F1/0044 , C22C1/1084 , C22C29/06
摘要： PROBLEM TO BE SOLVED: To provide a method of fabricating superfine grain cermet alloys, more particularly, a method of fabricating a TiC-base cermet alloy of superfine composite carbide grains with a homogeneous solid solution structure which does not comprise a core-rim structure in the carbide grain.
SOLUTION: The TiC-base cermet alloy of submicron grains with a homogeneous fine structure in the componential face which does not comprise the core-rim structure is fabricated by sintering nanocomposite powder (Ti-TM)C-(Co, Ni)(TM=transition metal) in which Ti-TM composite powder obtained by mechano-chemical synthesis (high energy ball-milling) and metallic Ni-Co are coexistent according to a general method.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：解决的问题：提供一种制造超细晶粒金属陶瓷合金的方法，更具体地，涉及一种制备具有均匀固溶体结构的超细复合碳化物晶粒的TiC基金属陶瓷合金的方法，所述均匀固溶体结构不包括芯 - 边缘结构在碳化物颗粒中。解决方案：通过烧结纳米复合粉末（Ti-TM）C-（Co，Ni）制备不含芯 - 边缘结构的组成面中具有均匀精细结构的亚微米晶粒的TiC基金属陶瓷合金，（TM =过渡金属），其中通过机械化学合成（高能球磨）和金属Ni-Co获得的Ti-TM复合粉末根据一般方法共存。版权所有（C）2005，JPO＆NCIPI

8. 发明专利

JP5380317B2 The magnetic tunnel junction device and a method of manufacturing the same 有权
公开(公告)号：JP5380317B2
公开(公告)日：2014-01-08
申请号：JP2010015152
申请日：2010-01-27
申请人：韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人：一縡愼 , 丙 ▲吉▼ 閔 , 慶浩申
IPC分类号： H01L43/08 , G11B5/39 , H01F10/32 , H01L21/8246 , H01L27/105 , H01L43/10 , H01L43/12
CPC分类号： H01L43/08 , B82Y25/00 , B82Y40/00 , G11C11/161 , H01F10/3254 , H01F10/3268 , H01F41/22 , H01F41/307 , H01L43/12

10. 发明专利

JP2012040000A Modified nucleotide and real-time polymerase reaction using the same 有权
标题翻译：使用相同的改性核和实时聚合反应
公开(公告)号：JP2012040000A
公开(公告)日：2012-03-01
申请号：JP2011091737
申请日：2011-04-18
申请人： Korea Advanced Inst Of Sci Technol , 韓国科学技術研究院Korea Institute Of Science And Tecnology
发明人： AN DAIRO
IPC分类号： C12N15/09 , C12Q1/68
CPC分类号： C07H19/20
摘要： PROBLEM TO BE SOLVED: To provide modified nucleotides and a real-time polymerase reaction using the same.SOLUTION: Nucleotides to which a fluorescent substance is bonded, a composition for the real-time polymerase reaction containing the nucleotides, an analysis kit, and an analysis method are provided. Nucleotides which are one of polymerase reaction substrates are chemically modified to impart a function of generating fluorescent signals in addition to a substrate function. Consequently, since there is no need to produce a probe, it is economical, and the nucleotides are easily applicable to various real-time polymerase reactions such as PCR (polymerase chain (amplification) reaction), RCA (rolling circle amplification) and isothermal polymerization reaction. Further, analytical performance is also excellent compared with conventional methods.
摘要翻译：待解决的问题：提供修饰的核苷酸和使用其的实时聚合酶反应。提供了与荧光物质结合的核苷酸，含有核苷酸的实时聚合酶反应的组合物，分析试剂盒和分析方法。作为聚合酶反应底物之一的核苷酸被化学修饰以赋予除了底物功能之外产生荧光信号的功能。因此，由于不需要生成探针，因此经济，核苷酸容易适用于PCR（聚合酶链式（扩增）反应），RCA（滚动循环扩增），等温聚合等各种实时聚合酶反应反应。此外，与常规方法相比，分析性能也优异。版权所有（C）2012，JPO＆INPIT

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