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81. 发明申请

US20110016642A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION 有权
标题翻译：包含至少一种无色溶剂/ THIOL前体的染料组合物和使用该组合物的染色方法
公开(公告)号：US20110016642A1
公开(公告)日：2011-01-27
申请号：US12679665
申请日：2008-09-23
申请人： Andrew Greaves , Nicolas Daubresse
发明人： Andrew Greaves , Nicolas Daubresse
IPC分类号： C09B49/00 , C07C237/02 , C07D403/12 , C07D401/12 , A45D34/00
CPC分类号： C09B62/78 , A61K8/411 , A61K8/49 , A61K8/4933 , A61Q5/10
摘要： The present invention relates to the dyeing of keratin materials using two colorless dye precursors, at least one of which contains a disulfide/thiol unit, said precursors reacting together chemically to form the color in situ. The process according to the invention makes it possible in the context of certain variants to solve the problems caused by the color generated during the process, while at the same time not degrading the efficacy of the coloration, and especially of the lightening effect. The colorations obtained are moreover powerful, chromatic, sparingly selective, and fast with respect to external agents such as sunlight, perspiration and especially shampoo.
摘要翻译：本发明涉及使用两种无色染料前体染色角蛋白材料，其中至少一种含有二硫化物/硫醇单元，所述前体通过化学反应一起在原位形成颜色。根据本发明的方法使得在某些变体的上下文中可以解决在该过程期间产生的颜色引起的问题，同时不降低着色的功效，特别是减轻效果。所获得的着色对于诸如阳光，汗水和特别是洗发剂的外部试剂而言是强大的，有色的，谨慎选择的和快速的。

82. 发明申请

US20100095807A1 SEPARATION REAGENT OF PLATINUM GROUP METAL, METHOD FOR SEPARATING AND RECOVERING PLATINUM GROUP METAL, AND AMIDE-CONTAINING TERTIARY AMINE COMPOUND 审中-公开
标题翻译：铂族金属的分离试剂，分离和回收铂族金属的方法，以及含胺的仲胺化合物
公开(公告)号：US20100095807A1
公开(公告)日：2010-04-22
申请号：US12640077
申请日：2009-12-17
申请人： Hirokazu NARITA , Mikiya TANAKA , Kazuko MORISAKU
发明人： Hirokazu NARITA , Mikiya TANAKA , Kazuko MORISAKU
IPC分类号： C22B11/00 , C07C237/02
CPC分类号： C22B11/04 , C22B3/001 , C22B3/0032 , C22B3/10 , C22B11/06 , Y02P10/234
摘要： The present invention provides a novel separation reagent capable of obtaining a high extraction % of rhodium in a chlorine-based acid solution, which has never existed heretofore, and a method for separating and recovering a platinum group metal using the same. An organic phase composed of an amide-containing tertiary amine separation reagent represented by the structural formula shown below is brought into contact with an acid solution containing a platinum group metal, thereby extracting rhodium, platinum and palladium with the organic phase. Among the metals extracted with the organic phase, rhodium is selectively back-extracted with a highly-concentrated hydrochloric acid solution, while palladium and platinum are back-extracted with a highly-concentrated nitric acid solution: wherein at least one of R1, R2 and R3 represents an amide group represented by: R1 to R3 other than the amide group and R4 to R6 represent a group selected from an optionally branched chain hydrocarbon group of 1 to 18 carbon atoms, an alicyclic hydrocarbon group of 1 to 10 carbon atoms, and an aromatic hydrocarbon group of 1 to 14 carbon atoms.
摘要翻译：本发明提供了一种能够在迄今为止从未存在的氯系酸溶液中获得高提取率的铑的新型分离试剂，以及使用该分离试剂的铂族金属的分离和回收方法。将由下述结构式表示的含酰胺的叔胺分离试剂构成的有机相与含有铂族金属的酸溶液接触，由有机相萃取铑，铂和钯。在有机相提取的金属中，用高度浓缩的盐酸溶液选择性地反萃取铑，钯和铂用高浓度硝酸溶液反萃取：其中R1，R2和 R3表示由除酰胺基以外的R1〜R3表示的酰胺基，R4〜R6表示选自1〜18个任意支链的烃基，1〜10个碳原子的脂环族烃基， 1〜14个碳原子的芳香族烃基。

83. 发明申请

US20090325940A1 Substituted 1,2-ethylenediamines, Methods for Preparing Them and Uses Thereof 审中-公开
标题翻译：取代的1,2-乙二胺，其制备方法及用途
公开(公告)号：US20090325940A1
公开(公告)日：2009-12-31
申请号：US12511474
申请日：2009-07-29
申请人： Christian Eickmeier , Stefan Peters , Klaus Fuchs , Niklas Heine , Sandra Handschuh , Cornelia Dorner-Ciossek , Klaus Klinder , Marcus Kostka
发明人： Christian Eickmeier , Stefan Peters , Klaus Fuchs , Niklas Heine , Sandra Handschuh , Cornelia Dorner-Ciossek , Klaus Klinder , Marcus Kostka
IPC分类号： A61K31/54 , A61K31/535 , A61K31/16 , C07D285/16 , C07D265/32 , C07C237/02
CPC分类号： C07K5/06026 , C07K5/06034 , C07K5/06191 , C07K5/0808 , C07K5/0812 , C07K5/0821
摘要： The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R1 to R15, A, B, L, i as well as X1-X4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
摘要翻译：本发明涉及通式（I）的取代的1,2-乙二胺，其中基团R 1至R 15，A，B，L，i以及X 1 -X 4如在说明书和权利要求书中所定义，以及其用于治疗阿尔茨海默病（AD）和类似疾病。

84. 发明申请

US20090281085A1 3-(4-FLUOROPHENYL)-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC ACTIVITY 有权
标题翻译： 3-（4-氟苯基）-3-羟基-2-氨基 - 丙酸和相关化合物具有活性
公开(公告)号：US20090281085A1
公开(公告)日：2009-11-12
申请号：US12364930
申请日：2009-02-03
申请人： Bertrand Leblond , Eric Beausoleil , Thierry Taverne , John E. Donello , Rong Yang , Cédric Chauvignac
发明人： Bertrand Leblond , Eric Beausoleil , Thierry Taverne , John E. Donello , Rong Yang , Cédric Chauvignac
IPC分类号： A61K31/55 , C07D207/04 , A61K31/40 , C07D265/30 , A61K31/5375 , C07D211/60 , A61K31/445 , C07C237/02 , A61K31/165 , C07D223/04 , A61P29/00
CPC分类号： C07D277/04 , C07C229/36 , C07C233/11 , C07C259/06 , C07C271/22 , C07C311/06 , C07D207/10 , C07D207/20 , C07D295/185
摘要： Compounds according to the formula below are disclosed herein: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译：本文公开了根据下式的化合物：还公开了与之相关的治疗方法，组合物和药物。

85. 发明申请

US20070123724A1 Method for preparing curable amide gellant compounds 有权
标题翻译：制备可固化酰胺胶凝剂化合物的方法
公开(公告)号：US20070123724A1
公开(公告)日：2007-05-31
申请号：US11290328
申请日：2005-11-30
申请人： Jennifer Belelie , Adela Goredema , Peter Odell , Eniko Toma
发明人： Jennifer Belelie , Adela Goredema , Peter Odell , Eniko Toma
IPC分类号： C07C237/02
CPC分类号： C07C231/02 , C08G69/26 , C08G69/28 , C09D11/34 , C07C233/34 , C07C233/36
摘要： Disclosed is a process for preparing a compound of the formula wherein R1 is an alkyl group having at least one ethylenic unsaturation, an arylalkyl group having at least one ethylenic unsaturation, or an alkylaryl group having at least one ethylenic unsaturation, R2 and R3 each, independently of the others, are alkylene groups, arylene groups, arylalkylene groups, or alkylarylene groups, and n is an integer representing the number of repeat amide units and is at least 1, said process comprising: (a) reacting a diacid of the formula HOOC—R2—COOH with a diamine of the formula in the absence of a solvent while removing water from the reaction mixture to form an acid-terminated oligoamide intermediate; and (b) reacting the acid-terminated oligoamide intermediate with a monoalcohol of the formula R1—OH in the presence of a coupling agent and a catalyst to form the product.
摘要翻译：公开了一种制备下式化合物的方法，其中R 1是具有至少一个烯属不饱和键的烷基，具有至少一个烯属不饱和键的芳基烷基或具有至少一个烯属不饱和键的烷基芳基烯键式不饱和键，R 2和R 3各自独立地为亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，n为代表重复酰胺单元的数目并且至少为1，所述方法包括：（a）使式Ⅳ的二酸与-in-line-formula description =“In-Line Formulas”end =“lead”→> HOOC-R' 在不存在溶剂的情况下，在从反应混合物中除去水的情况下，使用下式所示的二胺，在线式描述=“In-line Formula”中，以形成酸封端的低聚酰胺中间体; 和（b）使酸封端的低聚酰胺中间体与下式的一元醇反应：式中：=“引入”→R 1 -OH 在偶联剂和催化剂的存在下，<？in-line-formula description =“In-line formula”end =“tail”？>以形成产物。

86. 发明申请

US20070021353A1 Alpha ketoamide compounds as cysteine protease inhibitors 有权
标题翻译： α-酮酰胺化合物作为半胱氨酸蛋白酶抑制剂
公开(公告)号：US20070021353A1
公开(公告)日：2007-01-25
申请号：US11384023
申请日：2006-03-17
申请人： Michael Graupe , John Link , Michael Roepel
发明人： Michael Graupe , John Link , Michael Roepel
IPC分类号： A61K38/04 , C07C237/02
CPC分类号： C07C317/48 , C07C2601/02 , C07D213/32
摘要： The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
摘要翻译：本发明涉及半胱氨酸蛋白酶，特别是组织蛋白酶B，K，L，F和S的抑制剂的化合物，因此可用于治疗由这些蛋白酶介导的疾病。本发明涉及包含这些化合物的药物组合物及其制备方法。

87. 发明申请

US20070010680A1 Carboxamide derivative, processes for producing the same, and detergent composition 有权
标题翻译：羧酰胺衍生物，其制备方法和洗涤剂组合物
公开(公告)号：US20070010680A1
公开(公告)日：2007-01-11
申请号：US11474501
申请日：2006-06-26
申请人： Toshio Yajima , Akiko Kawashima
发明人： Toshio Yajima , Akiko Kawashima
IPC分类号： C07C237/02
CPC分类号： A61Q19/10 , A61K8/42 , A61Q5/02 , C07C233/36 , C11D1/75 , C11D1/90
摘要： To provide: a carboxamide derivative having reduced content of amide ester; a method for producing thereof; and a detergent composition containing the carboxamide derivative and having excellent low-temperature stability. One method for producing a carboxamide derivative is to react carboxamide, produced with a manufacturing method of carboxamide including 0.02% by weight to 0.18% by weight of amide ester, with hydrogen peroxide, wherein the method includes a carboxamide synthesis process to synthesize carboxamide by reacting diamine with fatty acid ester at a molar rate of 1.20 to 1.60. Another method for producing a carboxamide derivative is to react the carboxamide with monohaloalkylcarboxylic acid or a salt thereof. A carboxamide derivative is produced by the method for producing a carboxamide derivative. A detergent composition includes the carboxamide derivative. The carboxamide derivative is preferably amidoamine oxide or amide betaine.
摘要翻译：提供：具有降低的酰胺酯含量的羧酰胺衍生物; 其制造方法; 以及含有该羧酰胺衍生物并具有优异的低温稳定性的洗涤剂组合物。制备羧酰胺衍生物的一种方法是用与过氧化氢一起制备的包含0.02重量％至0.18重量％的酰胺酯的羧酰胺制备方法制得的甲酰胺，其中该方法包括通过使羧酰胺合成方法通过使二胺与脂肪酸酯的摩尔比为1.20至1.60。制备羧酰胺衍生物的另一种方法是使羧酰胺与单卤烷基羧酸或其盐反应。通过制备羧酰胺衍生物的方法制备羧酰胺衍生物。洗涤剂组合物包括甲酰胺衍生物。酰胺衍生物优选为酰氨基胺氧化物或酰胺甜菜碱。

88. 发明申请

US20060281810A1 Novel anthranilic acid derivatives 审中-公开
标题翻译：新型邻氨基苯甲酸衍生物
公开(公告)号：US20060281810A1
公开(公告)日：2006-12-14
申请号：US11451005
申请日：2006-06-12
申请人： Henrietta Dehmlow , Uwe Grether , Nicole Kratochwil , Robert Narquizian , Constantinos Panousis , Jens-Uwe Peters
发明人： Henrietta Dehmlow , Uwe Grether , Nicole Kratochwil , Robert Narquizian , Constantinos Panousis , Jens-Uwe Peters
IPC分类号： A61K31/277 , A61K31/195 , C07C255/60 , C07C237/02
CPC分类号： C07D215/26 , C07C235/56 , C07C255/54 , C07C317/22 , C07D213/643 , C07D213/65 , C07D249/08
摘要： The invention is concerned with novel anthranilic acid derivatives of formula (I) wherein R1 to R14 and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used as medicaments.
摘要翻译：本发明涉及式（I）的新型邻氨基苯甲酸衍生物，其中R 1至R 14和n如说明书和权利要求书中所定义，以及其生理上可接受的盐和酯。这些化合物是HM74A激动剂，可用作药物。

89. 发明申请

US20050192354A1 Method for preparing beta-alaninamides 失效
标题翻译： β-丙氨酰胺制备方法
公开(公告)号：US20050192354A1
公开(公告)日：2005-09-01
申请号：US11102828
申请日：2005-04-11
申请人： Stefan Hildbrand , Thomas Ruppen , Dario Veghini
发明人： Stefan Hildbrand , Thomas Ruppen , Dario Veghini
IPC分类号： C07C231/14 , C07C237/12 , C07C255/19 , C07D207/337 , C07D233/54 , C07D233/60 , C07D233/64 , A61K31/198 , C07C237/02
CPC分类号： C07D233/64 , C07C231/14 , C07C255/19 , Y02P20/55 , C07C237/12
摘要： Cyanoacetamides of the formula: and corresponding salts thereof; Nα-(cyanoacetyl)-L-histidines, of the formula: and salts, tautomers and esters thereof; and Nα-(cyanoacetyl)-3-methyl-L-histidines of the formula: and salts and esters thereof.
摘要翻译：下式的氰基乙酰胺及其相应的盐; N-（氰基乙酰基）-L-组氨酸，具有下式：及其盐，互变异构体和酯; 和Nα - （氰基乙酰基）-3-甲基-L-组氨酸，及其盐和酯。

90. 发明授权

US6165971A Use of amides of polymerized fatty acids as thickeners 失效
标题翻译：使用聚合脂肪酸的酰胺作为增稠剂
公开(公告)号：US6165971A
公开(公告)日：2000-12-26
申请号：US310123
申请日：1999-05-12
申请人： Knut Oppenlander , Michael Zirnstein , Kristin Tiefensee , Gunter Oetter
发明人： Knut Oppenlander , Michael Zirnstein , Kristin Tiefensee , Gunter Oetter
IPC分类号： C07H15/00 , A61K8/00 , A61K8/02 , A61K8/42 , A61K8/60 , A61K8/73 , A61Q5/00 , A61Q5/02 , B01F17/22 , B01F17/52 , B01F17/56 , C07C233/16 , C07C233/30 , C07C233/34 , C07C233/36 , C07C237/02 , C07H15/12 , C08G69/26 , C08G69/34 , C09K3/00 , C11D3/32
CPC分类号： A61K8/42 , A61K2800/48 , A61Q5/02 , A61Q19/10 , C07H13/06
摘要： The present invention relates to the use of amides of polymerized fatty acids as thickeners.Moreover, the invention relates to aqueous compositions comprising these amides as thickeners.
摘要翻译：本发明涉及聚合脂肪酸的酰胺作为增稠剂的用途。此外，本发明涉及包含这些酰胺作为增稠剂的含水组合物。

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