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    • 83. 发明授权
    • Multi-branched mannich base corrosion inhibitor and preparation method thereof
    • 多分支甘露糖基腐蚀抑制剂及其制备方法
    • US09493399B2
    • 2016-11-15
    • US14234854
    • 2012-04-27
    • Ling MaLei LiXiangjun KongMalike DilibaiXinping ZhenChunge NiuShengjun Bai
    • Ling MaLei LiXiangjun KongMalike DilibaiXinping ZhenChunge NiuShengjun Bai
    • C07C225/06C10G75/02C23F11/14C07C221/00C07C225/10C07C225/12C07C225/16
    • C07C225/06C07C221/00C07C225/10C07C225/12C07C225/16C10G75/02C23F11/141
    • The present invention relates to a multi-branched Mannich base corrosion inhibitor and the method for preparing thereof. The method comprises (1) adding 3˜7 moles ketone and 3˜7 moles aldehyde to reaction kettle, adjusting pH to 2˜6 with acid, controlling temperature to 20˜50° C. and stirring for 20˜30 mins; (2) adding 1 mole organic polyamine to the reaction kettle under stirring, or adding the pH-adjusted ketone, aldehyde and organic solvent to organic polyamine, controlling temperature to 60˜90° C. and reacting for 1˜3 hrs, and after completion of the reaction, heating the system to 110° C. under nitrogen to remove water; the organic polyamine is organic compound comprising three or more primary amine groups and/or secondary amine groups. The Mannich base corrosion inhibitor of the present invention shows characters of strong adsorption force, high film strength, high film compactness, increase in corrosion inhibition efficiency by at least 2%, and overcomes the disadvantages in prior art of few adsorption centers, single adsorption group and weak adsorption force to metal surfaces.
    • 本发明涉及多支化曼尼希碱缓蚀剂及其制备方法。 该方法包括:(1)向反应釜中加入3〜7摩尔酮和3〜7摩尔醛,用酸调节pH至2〜6,控制温度为20〜50℃,搅拌20〜30分钟; (2)在搅拌下向反应釜中加入1摩尔有机多胺,或将pH调节的酮,醛和有机溶剂加入到有机多胺中,控制温度为60〜90℃,反应1〜3小时后 反应完成,在氮气下将体系加热至110℃以除去水; 有机多胺是包含三个或更多个伯胺基和/或仲胺基团的有机化合物。 本发明的曼尼希碱防腐蚀剂具有吸附力强,膜强度高,膜致密性高,腐蚀抑制效率提高至少2%的特征,克服了少量吸附中心现有技术的缺点,单吸附组 对金属表面的吸附力弱。
    • 86. 发明申请
    • A MULTI-BRANCHED MANNICH BASE CORROSION INHIBITOR AND PREPARATION METHOD THEREOF
    • 多分支曼氏碱腐蚀抑制剂及其制备方法
    • US20140296575A1
    • 2014-10-02
    • US14234854
    • 2012-04-27
    • Ling MaLei LiXiangjun KongMalike DilibaiXinping ZhenChunge NiuShengjun Bai
    • Ling MaLei LiXiangjun KongMalike DilibaiXinping ZhenChunge NiuShengjun Bai
    • C07C225/06C07C225/10C07C221/00C07C225/12C07C225/16
    • C07C225/06C07C221/00C07C225/10C07C225/12C07C225/16C10G75/02C23F11/141
    • The present invention relates to a multi-branched Mannich base corrosion inhibitor and the method for preparing thereof. The method comprises (1) adding 3˜7 moles ketone and 3˜7 moles aldehyde to reaction kettle, adjusting pH to 2˜6 with acid, controlling temperature to 20˜50° C. and stirring for 20˜30 mins; (2) adding 1 mole organic polyamine to the reaction kettle under stirring, or adding the pH-adjusted ketone, aldehyde and organic solvent to organic polyamine, controlling temperature to 60˜90° C. and reacting for 1˜3 hrs, and after completion of the reaction, heating the system to 110° C. under nitrogen to remove water; the organic polyamine is organic compound comprising three or more primary amine groups and/or secondary amine groups. The Mannich base corrosion inhibitor of the present invention shows characters of strong adsorption force, high film strength, high film compactness, increase in corrosion inhibition efficiency by at least 2%, and overcomes the disadvantages in prior art of few adsorption centers, single adsorption group and weak adsorption force to metal surfaces.
    • 本发明涉及多支化曼尼希碱缓蚀剂及其制备方法。 该方法包括:(1)向反应釜中加入3〜7摩尔酮和3〜7摩尔醛,用酸调节pH至2〜6,控制温度为20〜50℃,搅拌20〜30分钟; (2)在搅拌下向反应釜中加入1摩尔有机多胺,或将pH调节的酮,醛和有机溶剂加入到有机多胺中,控制温度为60〜90℃,反应1〜3小时后 反应完成,在氮气下将体系加热至110℃以除去水; 有机多胺是包含三个或更多个伯胺基和/或仲胺基团的有机化合物。 本发明的曼尼希碱防腐蚀剂具有吸附力强,膜强度高,膜致密性高,腐蚀抑制效率提高至少2%的特征,克服了少量吸附中心现有技术的缺点,单吸附组 对金属表面的吸附力弱。
    • 88. 发明授权
    • 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
    • 3 {62-叔丁氧基 - 十氢 - 苯并{8E {9茚
    • US3897460A
    • 1975-07-29
    • US76502368
    • 1968-10-04
    • HOFFMANN LA ROCHE
    • HAJOS ZOLTAN GEORGE
    • C07C225/12C07C49/513C07C49/557C07C49/613C07C49/653C07C49/753C07C61/13C07C62/18C07C62/24C07C62/26C07C62/38C07C67/00C07C225/00C07C233/12C07C301/00C07C303/28C07C309/65C07C317/00C07D317/26C07D317/30C07J1/00C07J75/00C07D13/04
    • C07C309/00C07C45/292C07C45/515C07C45/673C07C45/676C07C45/75C07C61/13C07C62/26C07C62/38C07C2603/16C07D317/26C07D317/30C07C49/443C07C49/517C07C49/513C07C49/753
    • Total synthesis of known progestationally active steroidal materials. The steroids can be synthesized depending on the particular starting reactants selected by employing as intermediates bicyclic compounds of the formula

      WHEREIN M IS AN INTEGER HAVING A VALUE OF 1 TO 2; R4 is hydrogen or lower alkyl; Z is lower alkylenedioxy, CH(OR2) and carbonyl; R8 when taken alone is hydrogen; R9 when taken alone is lower alkoxycarbonyl, aryloxy-carbonyl, lower cycloalkyloxycarbonyl, carbonyl-halide, hydrogen, carboxy, formyl and methylene-X, where X is a leaving group and when taken together are methylene; with the proviso that when Z is carbonyl R8 when taken alone is hydrogen; R8 when taken alone is carbonyl halide, hydrogen, carboxy, formyl and methylene-X where X is a leaving group and when taken together are methylene and R2 is hydrogen, lower alkyl, lower alkoxy-lower alkyl, phenyl-lower alkyl, tetrahydropyranyl, lower alkanoyl, benzoyl, nitrobenzoyl, carboxy-lower alkanoyl, carboxy-benzoyl, trifluoroacetyl and camphorsulfonyl AND REACTING THEM IN THE CASE WHERE R8 and R9 taken together are methylene or R8 is hydrogen and R9 is methylene-X with Beta keto esters and other analogs of the formula

      WHEREIN R8 is selected from the group consisting of

      AND LOWER ALKYL; R7 is lower alkyl; R15 is selected from the group consisting of oxo, lower alkylenedioxy or (hydrogen and lower alkoxy); B is selected from the group consisting of lower alkoxy-carbonylmethylene, lower-aryloxy-carbonyl-methylene, cyanomethylene, lower alkyl sulfinyl-methylene, lower alkyl sulfonyl-methylene, and R25 and R26 are independently selected from the group consisting of hydrogen, hydroxyl and lower alkyl.
    • 已知的促孕活性甾体材料的全合成。 可以根据通过使用作为中间体选择的特定起始反应物来合成类固醇,式中的二环化合物是具有1至2的值的整数; R4是氢或低级烷基; Z是低亚烷基二氧基,CH(OR 2)和羰基; 单独使用时为R8; 当单独使用时,R 9为低级烷氧基羰基,芳氧基羰基,低级环烷氧基羰基,羰基卤化物,氢,羧基,甲酰基和亚甲基-X,其中X为离去基团,并且一起为亚甲基时; 条件是当Z为羰基时,当单独使用时为氢; 当单独使用时,R 8为羰基卤,氢,羧基,甲酰基和亚甲基-X,其中X为离去基团,当一起为亚甲基且R 2为氢时,低级烷基,低级烷氧基 - 低级烷基,苯基 - 低级烷基,四氢吡喃基, 低级烷酰基,苯甲酰基,硝基苯甲酰基,羧基 - 低级烷酰基,羧基 - 苯甲酰基,三氟乙酰基和樟脑磺酰,并反应其中R 8和R 9一起为亚甲基或R8为氢,R9为亚甲基-X,带有β-酮酯等 式WHERE R 8的类似物选自:和低级烷基; R7是低级烷基; R 15选自氧代,低级亚烷基二氧基或(氢和低级烷氧基); B选自低级烷氧基 - 羰基亚甲基,低级 - 芳氧基 - 羰基 - 亚甲基,氰基亚甲基,低级烷基亚磺酰基 - 亚甲基,低级烷基磺酰基 - 亚甲基,R 25和R 26独立地选自氢,羟基 和低级烷基。