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81. 发明授权

US09062147B2 Lactide copolymer, a preparation method thereof, and a resin composition including the same 有权
标题翻译：丙交酯共聚物，其制备方法和包含它们的树脂组合物
公开(公告)号：US09062147B2
公开(公告)日：2015-06-23
申请号：US14095647
申请日：2013-12-03
申请人： LG CHEM, LTD.
发明人： Jung-Min Sohn , Seung Young Park , Sung-Cheol Yoon , Do-Yong Shim
IPC分类号： C08G18/42 , C08G18/40 , C08L75/06 , C08L75/08 , C08G18/48 , C08G18/72 , C08G18/79 , C08G63/08 , C08G63/664 , C08G63/685 , C08G63/91 , C08G63/82
CPC分类号： C08G18/428 , C08G18/4009 , C08G18/4072 , C08G18/4244 , C08G18/4252 , C08G18/4266 , C08G18/4286 , C08G18/4887 , C08G18/725 , C08G18/792 , C08G63/08 , C08G63/664 , C08G63/6852 , C08G63/823 , C08G63/912 , C08L75/06 , C08L75/08
摘要： The present invention relates to a lactide copolymer having good flexibility in addition to excellent properties such as mechanical properties and processability and preferably being applicable as a packaging material, a preparation method thereof, and a resin composition including the same. The lactide copolymer includes two or more specific block copolymerized repeating units that the hard segments of polylactide repeating units are connected to both ends of the soft segments of polyether polyol repeating unit, and the block copolymerized repeating units are connected to each other through the intermediation of urethane connecting groups derived from polyvalent isocyanate compound of which the average equivalent of isocyanate group per a molecule is more than 2 and less than 3.
摘要翻译：本发明涉及具有良好的柔韧性的丙交酯共聚物，除了具有优异的性能如机械性能和加工性，并且优选适用于包装材料，其制备方法和包含其的树脂组合物。丙交酯共聚物包括两个或更多个特定的嵌段共聚重复单元，其中聚丙交酯重复单元的硬链段连接到聚醚多元醇重复单元的软链段的两端，并且嵌段共聚重复单元通过以下方式彼此连接：衍生自每分子的异氰酸酯基平均当量大于2且小于3的多价异氰酸酯化合物的氨基甲酸酯连接基团。

82. 发明授权

US08911760B2 Copolymers having polyisobutylene and biodegradable polymer segments 有权
标题翻译：具有聚异丁烯和可生物降解聚合物链段的共聚物
公开(公告)号：US08911760B2
公开(公告)日：2014-12-16
申请号：US12650234
申请日：2009-12-30
申请人： Mark Boden , Marlene C. Schwarz , Frederick H. Strickler , Rudolf Faust , Umaprasana Ojha , Tomoya Higashihara
发明人： Mark Boden , Marlene C. Schwarz , Frederick H. Strickler , Rudolf Faust , Umaprasana Ojha , Tomoya Higashihara
IPC分类号： A61F13/00 , A61K31/74 , C08G63/91 , C08L67/00 , C08G79/02 , C08G63/02 , C08G63/08 , C08G64/00 , C08G64/18 , A61L27/16 , A61L27/54 , A61L27/58 , A61L29/04 , A61L29/14 , A61L29/16 , A61L31/04 , A61L31/14 , A61L31/16 , C08G18/42 , C08G18/62 , C08G18/76 , C08G63/00 , C08G63/06 , C08G64/42 , C08G69/08
CPC分类号： C08F299/04 , A61L27/165 , A61L27/54 , A61L27/58 , A61L29/041 , A61L29/148 , A61L29/16 , A61L31/048 , A61L31/148 , A61L31/16 , A61L2300/00 , C08G18/4266 , C08G18/6204 , C08G18/7671 , C08G63/00 , C08G63/06 , C08G63/912 , C08G64/18 , C08G64/42 , C08G69/08 , C08G2261/126 , C08L53/02
摘要： The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.
摘要翻译：本发明涉及具有一个或多个聚异丁烯链段和一个或多个生物可降解聚合物链段的共聚物，制备这种共聚物的方法，含有这种共聚物的医药制品，以及制备这种医疗制品的方法。根据本发明的某些方面，提供了包含多个聚异丁烯链段和多个可生物降解的聚合物链段的共聚物。根据本发明的某些方面，提供了共聚物，其包含氨基甲酸酯键，脲键，酰胺键，酯键，酸酐键，碳酸酯键，通常描述为“点击”化学键的键，以及两种或更多种类型这样的联系。

83. 发明申请

US20130108821A1 SURGICAL BARRIERS POSSESSING CLINICALLY IMPORTANT ABSORPTION CHARACTERISTICS 审中-公开
标题翻译：临床护理人员临床重要吸收特征
公开(公告)号：US20130108821A1
公开(公告)日：2013-05-02
申请号：US13624101
申请日：2012-09-21
申请人： BVW HOLDING AG
发明人： Hinrich Wiese , Joerg Tessmar , Martina Kessler , Lukas Bluecher , Michael Milbocker
IPC分类号： C08G63/06 , B32B38/04 , B32B3/02 , B32B27/08 , B32B3/26
CPC分类号： C08G63/06 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/148 , A61L31/16 , A61L2300/604 , B32B3/02 , B32B3/266 , B32B27/08 , B32B38/04 , C08G18/12 , C08G18/3203 , C08G18/3234 , C08G18/4018 , C08G18/4266 , C08G18/4277 , C08G18/428 , C08G18/44 , C08G18/48 , C08G18/4833 , C08G18/4854 , C08G18/4887 , C08G18/73 , C08G18/755 , C08G63/66 , C08G63/664 , C08G65/2603 , C08G2230/00 , C08G2261/126 , C08L71/02 , C08L2205/05 , Y10T428/239 , Y10T428/24331 , Y10T428/31554 , C08L75/04 , C08L67/00
摘要： The present disclosure provides copolymers useful in medical devices. For example, the disclosure provides copolymers comprising the polymerization product ester block, ether blocks and diisocyanates. In certain embodiments, the disclosure provides a medical copolymer for implantation comprising ester blocks and ether blocks, wherein: the ester blocks comprise a negative free energy transfer and the ether blocks comprise a positive free energy transfer, the ether and ester blocks are less than 1/10 the length of said copolymer, and, the blocks are distributed such that no domain of contiguous blocks possessing the same polarity of free energy transfer are less than ⅓ of the molecular weight of the copolymer. The disclosure further provides methods of making the aforementioned polymers, and medical devices comprising the polymers.
摘要翻译：本公开提供了可用于医疗装置的共聚物。例如，本公开提供了包含聚合产物酯嵌段，醚嵌段和二异氰酸酯的共聚物。在某些实施方案中，本公开提供了用于植入的医用共聚物，其包含酯嵌段和醚嵌段，其中：酯嵌段包含负自由能转移，并且所述醚嵌段包含正的自由能转移，所述醚和酯嵌段小于1 所述共聚物的长度为10，并且所述嵌段被分布成使得不具有相同极性的自由能转移的连续嵌段的区域小于共聚物分子量的1/3。本公开进一步提供了制备上述聚合物的方法和包含聚合物的医疗装置。

84. 发明申请

US20120178872A1 HYDROPHOBIC POLYMER FOR PRODUCING MEDICAL DEVICES VISIBLE IN MRI 有权
标题翻译：用于生产可见MRI的医疗器械的疏水性聚合物
公开(公告)号：US20120178872A1
公开(公告)日：2012-07-12
申请号：US13382667
申请日：2010-07-07
申请人： Sebastien Blanquer , Jean Coudane , Renaud De Tayrac , Xavier Garric , Vincent Letouzey , Olivier Guillaume
发明人： Sebastien Blanquer , Jean Coudane , Renaud De Tayrac , Xavier Garric , Vincent Letouzey , Olivier Guillaume
IPC分类号： C09D133/08 , C09D5/23 , C09D167/04
CPC分类号： A61L27/50 , A61K49/128 , A61L27/16 , A61L29/041 , A61L29/18 , A61L31/048 , A61L31/18 , C08F8/30 , C08F8/42 , C08F20/14 , C08F20/16 , C08G18/4266 , C08G18/4269 , C08G18/4272 , C08G18/4275 , C08G18/4277 , C08G18/428 , C08G18/4283 , C08G85/002 , C08G85/004 , C08G2230/00 , C08L33/10 , C08F220/18
摘要： The present invention relates to a hydrophobic polymer used in particular to produce and/or coat medical devices, in particular implantable medical devices, that are visible in magnetic resonance imaging, characterized in that it comprises at least one monomer unit on which is grafted a chelating ligand of a paramagnetic ion complexed with such a paramagnetic ion, said monomer unit having at least one carbonyl group, said monomer unit comprising, prior to grafting, at least one hydrogen atom in the a position of said at least one carbonyl group, and said grafting of the chelating ligand taking place in the area of said at least one hydrogen atom in the a position of said at least one carbonyl group.
摘要翻译：本发明涉及特别用于生产和/或涂覆在磁共振成像中可见的医疗装置，特别是可植入医疗装置的疏水性聚合物，其特征在于，其包含至少一个单体单元，其上接枝有螯合物所述单体单元具有至少一个羰基，所述单体单元在接枝之前包含在所述至少一个羰基的一个位置上的至少一个氢原子和所述至少一个羰基的所述单体单元，在所述至少一个羰基的一个位置上在所述至少一个氢原子的区域中发生螯合配体的接枝。

85. 发明申请

US20090177226A1 Bioabsorbable Surgical Compositions 审中-公开
标题翻译：生物可吸收外科组合物
公开(公告)号：US20090177226A1
公开(公告)日：2009-07-09
申请号：US12351492
申请日：2009-01-09
申请人： Jon Reinprecht , Nadya Belcheva , Ahmad Robert Hadba , Ferass Abuzaina
发明人： Jon Reinprecht , Nadya Belcheva , Ahmad Robert Hadba , Ferass Abuzaina
IPC分类号： A61B17/03 , A61L24/08
CPC分类号： C08G18/4252 , A61L24/0042 , A61L24/043 , A61L24/046 , C08G18/10 , C08G18/4266 , C08G63/672 , C08G63/6856 , C08G63/916 , C08G2190/00 , C08G2230/00 , C09J175/06 , C08L71/02 , C08G18/42
摘要： Compounds are provided which can form bioabsorbable compositions useful as adhesives or sealants for medical/surgical applications.
摘要翻译：可以提供可形成用作医疗/外科应用的粘合剂或密封剂的生物可吸收组合物的化合物。

86. 发明授权

US06372876B1 Use of polyurethanes which are soluble or dispersible in water as aids in cosmetic and pharmaceutical compositions, and polyurethanes which contain polylactic acid polyols as copolymerized units 失效
标题翻译：使用可溶于水或分散于水中的聚氨酯作为化妆品和药物组合物的助剂，以及含有聚乳酸多元醇作为共聚单元的聚氨酯
公开(公告)号：US06372876B1
公开(公告)日：2002-04-16
申请号：US08367327
申请日：1995-01-24
申请人： Son Nguyen Kim , Axel Sanner , Karin Sperling-Vietmeier
发明人： Son Nguyen Kim , Axel Sanner , Karin Sperling-Vietmeier
IPC分类号： C08G1830
CPC分类号： C08G18/0819 , A61K8/87 , A61K9/2031 , A61K9/2853 , A61Q5/06 , C08G18/4266 , C08G18/428 , C08G18/4283 , C08G18/6659 , C08G2170/80 , C09J175/06 , Y10S424/01
摘要： The use of polyurethanes which are—soluble or dispersible in water and are composed of a) at least one compound which contains two or more active hydrogens per molecule, b) at least one diol containing acid groups or salt groups and c) at least one diisocyanate with a glass transition temperature of at least 15° C. and acid numbers of from 12 to 150 or the salts of these polyurethanes as aids in cosmetic and pharmaceutical compositions, and of polyurethanes which are soluble or dispersible in water and which contain (a) at least 5 mol % of a polycondensate of lactic acid and of a polyol of the formula where Y is a radical derived from a dihydric to tetrahydric alcohol n is 1-50 and m is 1-4 as copolymerized units.
摘要翻译：使用在水中可溶或可分散的聚氨酯，其由以下组成：a）至少一种每分子含有两个或多个活性氢的化合物，b）至少一种含有酸基团或盐基团的二元醇，和c）至少一种二异氰酸酯与至少15℃的玻璃化转变温度和12至150的酸值或这些聚氨酯的盐作为化妆品和药物组合物中的辅助剂，以及可溶于或可分散在水中的聚氨酯，其含有（a）至少5摩尔％的缩水甘油酸和式I的多羟基化合物是衍生自二元至四元醇的基团为1-50且m为1〜4的共聚单元。

87. 发明授权

US06310171B1 Resin composition with biodegradability and foamability 失效
标题翻译：具有生物降解性和发泡性的树脂组合物
公开(公告)号：US06310171B1
公开(公告)日：2001-10-30
申请号：US09530480
申请日：2000-04-28
申请人： Hiroshi Naito , Masahiro Yama , Takahiro Kubo , Katsumi Onishi , Tsunahiro Nakae
发明人： Hiroshi Naito , Masahiro Yama , Takahiro Kubo , Katsumi Onishi , Tsunahiro Nakae
IPC分类号： C08G1808
CPC分类号： C08G63/912 , C08G18/4266 , C08G18/4283 , C08G2101/00 , C08G2230/00
摘要： The present invention relates to a resin composition for foam, which is used as a packing cushioning material, and an object thereof is to provide said composition which has biodegradability and is made from a principal raw material, lactic acid capable of contributing to the protection of global environment. The object can be attained by a resin composition having biodegradability and expandability, comprising a high-molecular weight polylactic acid having a melt viscosity of 0.01 to 50 in terms of a melt index value (MI), characterized in that said resin composition is prepared by compounding 0.1 to 5% by weight of at least one compound, which is selected from a polyisocyanate having an isocyanate group of not less than 2.0 equivalents/mol, an epoxy compound having an epoxy group of more than 2.0 equivalents/mol and an acid anhydride having an anhydrous carboxyl group of more than 2.0 equivalents/mol, with a prepolymer made of lactic acid wherein a molar ratio of a L-isomer to a D-isomer is within arange from 95:5 to 60:40 or from 40:60 to 5:95, and reacting the resulting mixture.
摘要翻译：本发明涉及一种泡沫塑料用树脂组合物，其用作填料缓冲材料，其目的在于提供具有生物降解性的组合物，其由主要原料制成，能够有助于保护的乳酸全球环境。该目的可以通过具有生物可降解性和可扩展性的树脂组合物来实现，其包含以熔体指数值（MI）计算的熔体粘度为0.01至50的高分子量聚乳酸，其特征在于所述树脂组合物由配合0.1〜5重量％的至少一种化合物，其选自异氰酸酯基不大于2.0当量/摩尔的多异氰酸酯，环氧基大于2.0当量/摩尔的环氧化合物和酸酐具有大于2.0当量/摩尔的无水羧基与由乳酸制备的预聚物，其中L-异构体与D-异构体的摩尔比在95:5至60:40或40:60之间的范围内至5:95，并使所得混合物反应。

88. 发明授权

US06258917B1 Extrudable thermoplastic elastomeric urea-extended polyurethane 有权
标题翻译：可挤压热塑性弹性体尿素延伸聚氨酯
公开(公告)号：US06258917B1
公开(公告)日：2001-07-10
申请号：US09157588
申请日：1998-09-21
申请人： Edwin C. Slagel
发明人： Edwin C. Slagel
IPC分类号： C08G1832
CPC分类号： C08G18/758 , C08G18/0895 , C08G18/10 , C08G18/12 , C08G18/4266 , C08G18/4277 , C08G18/4854 , C08G18/3237 , C08G18/324
摘要： An extrudable urea-extended thermoplastic polyurethane elastomer is formed from at least one aliphatic diisocyanate, at least one polyester glycol or polyether glycol, and at least one diamine curing agent. At least one second diamine curing agent and/or at least one extrusion processing aid may be included. The polyurethane has high-temperature-resistance and is thus extrudable at high temperatures. The polyurethane is also strong and durable. The polyurethane can be liquid-cast, transfer-molded, sprayed, and extruded without changing either the chemistry or stoichiometry of the polyurethane. The polyurethane may be used for making vehicle air bags or other any application for thermoplastic urethanes which requires increased thermal stability.
摘要翻译：可挤出的尿素延伸的热塑性聚氨酯弹性体由至少一种脂族二异氰酸酯，至少一种聚酯二醇或聚醚二醇和至少一种二胺固化剂形成。可以包括至少一种第二种二胺固化剂和/或至少一种挤出加工助剂。聚氨酯具有耐高温性，因此可在高温下挤出。聚氨酯也坚固耐用。聚氨酯可以液态铸塑，转移模塑，喷涂和挤出，而不改变聚氨酯的化学成分或化学计量。聚氨酯可用于制造车辆气囊或其它任何需要增加热稳定性的热塑性聚氨酯的应用。

89. 发明授权

US6090886A Finely dispersed polyurethane polyurea crosslinked particles and process for producing the same 失效
标题翻译：细分散聚氨酯聚脲交联颗粒及其制备方法
公开(公告)号：US6090886A
公开(公告)日：2000-07-18
申请号：US599976
申请日：1996-02-14
申请人： Hidetoshi Konno , Mitsuo Kase , Ichiro Muramatsu , Noboru Okoshi
发明人： Hidetoshi Konno , Mitsuo Kase , Ichiro Muramatsu , Noboru Okoshi
IPC分类号： C08G18/00 , C08G18/08 , C08G18/10 , C08G18/42 , C08G18/62 , C08G18/65 , C08G18/80 , C08G18/34
CPC分类号： C08G18/8048 , C08G18/0823 , C08G18/0866 , C08G18/10 , C08G18/4266 , C08G18/6254
摘要： Finely dispersed polyurethane polyurea crosslinked particles having an average particle diameter of not greater than 1 .mu.m and essentially comprising (A) an ion-forming polyol, (B) a polyisocyanate, and (C) a polyamine; and a process for producing the same are disclosed. The present invention provides finely dispersed polyurethane polyurea crosslinked particles and a process for producing the same; the dispersed particles being firmly crosslinked and having an average particle diameter of not greater than 1 .mu.m, and the particle dispersion having high preservation stability, preventing the core substance, if encapsulated therein, from undergoing denaturation, and exhibiting per se film-forming properties to provide a film excellent in water resistance, solvent resistance and chemical resistance.
摘要翻译：基本上包含（A）离子形成多元醇，（B）多异氰酸酯和（C）多胺的平均粒径不大于1μm的细分散的聚氨酯聚脲交联颗粒; 并公开了其制造方法。本发明提供精细分散的聚氨酯聚脲交联颗粒及其制备方法。分散颗粒牢固交联并且平均粒径不大于1μm，并且具有高保存稳定性的颗粒分散体，防止核心物质（如果包封在其中）经历变性，并且显示出成膜性以提供耐水性，耐溶剂性和耐化学性优异的膜。

90. 发明授权

US5614564A Degradable foam and the method for its production 失效
标题翻译：可降解泡沫及其生产方法
公开(公告)号：US5614564A
公开(公告)日：1997-03-25
申请号：US279790
申请日：1994-07-25
申请人： Jin-Taek Hwang , Seung-Ho Jeon , Won-Bum Jung , Sung-Ju Seo
发明人： Jin-Taek Hwang , Seung-Ho Jeon , Won-Bum Jung , Sung-Ju Seo
IPC分类号： C08J9/04 , C08G18/40 , C08G18/42 , C08G18/64 , C08H8/00 , C08J3/09 , C08J9/00 , C08L67/00 , C08L67/02 , C08L67/04 , C08L97/00 , C08L97/02 , C08G18/00
CPC分类号： C08H8/00 , C08G18/4081 , C08G18/4238 , C08G18/4266 , C08G18/6484 , C08G18/6492 , C08J3/095 , C08J9/0061 , C08L67/02 , C08L67/04 , C08L97/02 , C08G2101/005 , C08G2101/0083 , C08G2230/00 , C08J2375/04 , C08J2397/02 , C08J2497/00 , C08L2201/06
摘要： The present invention relates to a lignocellulose solution and its production method, further to a degradable foam and its production method. The degradable foam of the present invention is produced by foaming and hardening with an ordinary foaming agent and hardening agent the lignocellulose solution which is obtained by dissolving lignocellulose and/or its derivatives in aliphatic polyester polyol, or else such solution with photodegradation promoters added thereto; and is also produced by foaming and hardening with an ordinary foaming agent and an ordinary hardening agent the lignocellulose solution which is obtained by dissolving lignocellulose and/or its derivatives in the bio-/photo-degradable aliphatic polyester polyol which is obtained by a polycondensation of the dicarboxylic acid composed of aliphatic dicarboxylic acid and keto containing dicarboxylic acid or its ester and aliphatic diol.The degradable foam of the present invention excells in its degradability, mechanical properties and economic efficiency.
摘要翻译：本发明涉及一种木质素纤维素溶液及其制备方法，进一步涉及可降解泡沫及其制备方法。本发明的可降解泡沫体通过使用普通发泡剂和硬化剂将木质纤维素和/或其衍生物溶解在脂肪族聚酯多元醇中而获得的木质纤维素溶液发泡和硬化，或者添加了光降解促进剂的溶液; 并且还通过使用普通发泡剂和普通硬化剂将木质纤维素和/或其衍生物溶解在通过将木质纤维素和/或其衍生物溶解在生物/光可降解脂肪族聚酯多元醇中获得的木质纤维素溶液进行发泡和硬化来制备，所述生物/光可降解脂肪族聚酯多元醇是通过由脂肪族二羧酸和含有二羧酸的酮或其酯和二元醇组成的二羧酸。本发明的可降解泡沫的降解性，机械性能和经济性优异。

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