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81. 发明申请

US20060034762A1 Method for measuring skin absorbability 审中-公开
标题翻译：皮肤吸收性测定方法
公开(公告)号：US20060034762A1
公开(公告)日：2006-02-16
申请号：US11259882
申请日：2005-10-27
申请人： Eriko Takeoka , Ryuichi Takamoto , Toshio Yanaki
发明人： Eriko Takeoka , Ryuichi Takamoto , Toshio Yanaki
IPC分类号： A61K49/00 , C12Q1/00
CPC分类号： A61K8/342 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q9/00 , G01N33/5088
摘要： A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.
摘要翻译：用于测量物质的皮肤吸收性的方法，其包括测量渗入毛囊中的物质的量; 并使用所得数据作为表示通过皮肤孔吸收的物质的量的指标，从而确定通过皮肤孔吸收的物质的量和测量物质的皮肤吸收性的方法，其包括使物质进入与模拟皮肤表面层的薄膜的第一表面接触，膜的第二表面与人造皮脂接触; 并且通过使用物质转移到人造皮脂的程度作为指标来评估物质的皮脂转移性。还公开了用于执行本发明的测量方法的套件。

82. 发明授权

US06685927B2 Topical application of chromophores for hair removal 失效
标题翻译：用于脱毛的发色团的局部应用
公开(公告)号：US06685927B2
公开(公告)日：2004-02-03
申请号：US09965354
申请日：2001-09-27
申请人： Chryslain Sumian , Wolfgang Neuberger , Serge Mordon
发明人： Chryslain Sumian , Wolfgang Neuberger , Serge Mordon
IPC分类号： A61K715
CPC分类号： A61Q9/04 , A61K8/0241 , A61K8/49 , A61K2800/412 , A61K2800/438 , A61K2800/56 , A61K2800/81 , A61K2800/82 , A61K2800/83 , A61Q9/00
摘要： A device and method is disclosed for permanent or semi-permanent removal of hair through the activation of microparticles introduced into hair follicles. Microparticles are incorporated into a composition that is topically applied to the skin. These microparticles containing or consisting of chromophores or chemically activated molecules are of a variety of shapes and sizes. Microparticles are within a size range of 1 micron to 70 microns, and preferably between 10 and 50 microns. Microparticles of this size and variety of shapes enter hair follicles on all areas of the skin without entering other areas of the skin, such as the stratum corneum or sweat gland channels. Treatment of the skin with electromagnetic radiation, ultrasonic radiation or chemical means activates the chromophore or chemically activated compounds, thus destroying the hair follicle without damaging other areas of the skin. In another embodiment, microparticles further contain nanoparticles released further into the hair follicle by use of a solvent or other method, allowing chromophores or chemically activated molecules to penetrate deeper into the follicle and avoid structures such as the sebaceous gland.
摘要翻译：公开了通过引入毛囊的微粒的活化来永久或半永久性去除毛发的装置和方法。将微粒掺入局部施用于皮肤的组合物中。含有或由发色团或化学活化分子组成的这些微粒具有各种形状和尺寸。微粒的尺寸范围为1微米至70微米，优选为10至50微米。这种尺寸和各种形状的微粒在皮肤的所有区域都进入毛囊，而不会进入皮肤的其他区域，例如角质层或汗腺通道。用电磁辐射，超声辐射或化学方法治疗皮肤会激活发色团或化学活化的化合物，从而破坏毛囊而不损害皮肤的其他部位。在另一个实施方案中，微粒还包含通过使用溶剂或其它方法进一步释放到毛囊中的纳米颗粒，使得发色团或化学活化分子能够更深地渗入毛囊并避免诸如皮脂腺的结构。

83. 发明申请

US20030165577A1 Novel compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use 有权
标题翻译：含有抗微生物剂和尿素用于治疗皮肤病的新型组合及其使用方法
公开(公告)号：US20030165577A1
公开(公告)日：2003-09-04
申请号：US10365321
申请日：2003-02-11
申请人： Bradley Pharmaceuticals, Inc.
发明人： Dileep Bhagwat , Bradley P. Glassman , Daniel Glassman
IPC分类号： A61K033/04 , A61K031/63 , A61K031/4162 , A61K031/355 , A61K031/17
CPC分类号： A61Q17/005 , A61K8/466 , A61Q5/00 , A61Q9/00 , A61Q19/00 , A61Q19/02 , Y10S514/859
摘要： Topical compositions which include urea and an antimicrobial agent, particularly sulfacetamide or metronidazole, are described. Sulfacetamide compositions further including sulfur are also described. Methods for treating dermatological disorders using the compositions are also described.
摘要翻译：描述了包括尿素和抗微生物剂，特别是磺胺乙酰胺或甲硝唑的局部组合物。还描述了进一步包含硫的硫代乙酰胺组合物。还描述了使用该组合物治疗皮肤病的方法。

84. 发明申请

US20030165429A1 Method for measuring skin absorbability of a substance 审中-公开
标题翻译：测量物质皮肤吸收性的方法
公开(公告)号：US20030165429A1
公开(公告)日：2003-09-04
申请号：US10238520
申请日：2002-09-09
申请人： Shiseido Co., Ltd.
发明人： Eriko Takeoka , Ryuichi Takamoto , Toshio Yanaki
IPC分类号： C12Q001/00 , A61K049/00 , A61K007/06
CPC分类号： A61K8/342 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q9/00 , G01N33/5088
摘要： A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.
摘要翻译：用于测量物质的皮肤吸收性的方法，其包括测量渗入毛囊中的物质的量; 并使用所得数据作为表示通过皮肤孔吸收的物质的量的指标，从而确定通过皮肤孔吸收的物质的量和测量物质的皮肤吸收性的方法，其包括使物质进入与模拟皮肤表面层的薄膜的第一表面接触，膜的第二表面与人造皮脂接触; 并且通过使用物质转移到人造皮脂的程度作为指标来评估物质的皮脂转移性。还公开了用于执行本发明的测量方法的套件。

85. 发明授权

US5980873A Additive for cosmetics and other topically applied materials 失效
标题翻译：化妆品和其他局部应用材料的添加剂
公开(公告)号：US5980873A
公开(公告)日：1999-11-09
申请号：US888948
申请日：1997-07-07
申请人： Ales M. Kapral
发明人： Ales M. Kapral
IPC分类号： A61K8/02 , A61K8/20 , A61K8/21 , A61Q3/00 , A61Q9/00 , A61Q9/02 , A61Q9/04 , C11D7/08 , C11D7/12 , C11D11/00 , A61K7/043 , A61K7/00
CPC分类号： C11D11/0017 , A61K8/02 , A61K8/20 , A61K8/21 , A61Q3/00 , A61Q9/00 , A61Q9/02 , A61Q9/04 , C11D7/08 , A61K2800/28
摘要： A keratin composition which incorporates a metallic salt of fluoric acid increases the permeability of the user's skin allowing greater affect by the active agent. The affect of the salt of hydrofluoric acid is increased through the use of either water or alcohol mixed therewith. The composition so formed is useful for pharmaceutical treatments, topical cleansers, soaps, creams, and as additives to a variety of cosmetics.
摘要翻译：含有氟酸金属盐的角蛋白组合物增加了使用者皮肤的渗透性，从而允许活性剂的较大影响。通过使用与其混合的水或醇来增加氢氟酸盐的影响。如此形成的组合物可用于药物治疗，局部清洁剂，肥皂，霜剂和作为各种化妆品的添加剂。

86. 发明授权

US5902573A Keratin softening technique and apparatus 失效
标题翻译：角蛋白软化技术及装置
公开(公告)号：US5902573A
公开(公告)日：1999-05-11
申请号：US954134
申请日：1997-10-20
申请人： Ales M. Kapral
发明人： Ales M. Kapral
IPC分类号： A61K8/02 , A61K8/20 , A61K8/21 , A61Q3/00 , A61Q9/00 , A61Q9/02 , A61Q9/04 , C11D7/08 , C11D7/12 , C11D11/00 , A61K7/06 , A61K7/00
CPC分类号： A61Q9/04 , A61K8/02 , A61K8/20 , A61K8/21 , A61Q3/00 , A61Q9/00 , A61Q9/02 , C11D11/0017 , C11D7/08 , A61K2800/28
摘要： A treatment mechanism for keratin, including hair and epidermis, in which a chemical is applied in a substantially dry state. The chemical is adapted to release sulfur from said keratin, thereby softening it. The keratin is then rinsed with water, preparing the keratin to be exfoliated from the skin or, in the case of hair, cut or shaved. The preferred chemical is a salt of fluoric acid being either tin or sodium based.
摘要翻译：用于角蛋白的治疗机制，包括头发和表皮，其中以基本干燥的状态施用化学品。该化学物质适于从所述角蛋白释放硫，从而使其软化。然后用水冲洗角蛋白，制备角质层从皮肤脱落，或者在头发的情况下切割或剃刮。优选的化学物质是以锡或钠为基础的氟酸盐。

87. 发明申请

WO2014093507A2 PVOH COPOLYMERS FOR PERSONAL CARE APPLICATIONS 审中-公开
标题翻译：用于个人护理应用的PVOH共聚物
公开(公告)号：WO2014093507A2
公开(公告)日：2014-06-19
申请号：PCT/US2013/074429
申请日：2013-12-11
申请人： SEKISUI SPECIALTY CHEMICALS AMERICA, LLC
发明人： WURM, David , GRISSOM, Christa , VICARI, Richard
IPC分类号： A61K8/34 , A61Q19/00 , A61K8/81 , A61Q19/04 , A61K8/86 , A61K8/02
CPC分类号： A61K8/8129 , A61K8/0212 , A61K8/345 , A61K8/8158 , A61K8/817 , A61K8/8182 , A61K2800/28 , A61K2800/594 , A61Q1/10 , A61Q9/00 , A61Q19/00 , G06Q30/0621
摘要： Various cosmetic compositions are disclosed that may be useful in face masks, epilatories, and pore strips. Also disclosed is a method of designing a cosmetic composition that may include: receiving a request to tailor a cosmetic composition to have a selected property or a selected property set. The method may be used to design and manufacture cosmetic compositions, such as epilatory compositions, face or skin care mask compositions used for cleansing and/or exfoliating the skin, and eyeliners, among others, having advantageous properties.
摘要翻译：公开了各种化妆品组合物，其可用于面罩，表皮和孔带。还公开了一种设计化妆品组合物的方法，其可以包括：接收定制化妆品组合物以具有所选择的性质或选定的性质组的请求。该方法可用于设计和制造化妆品组合物，例如用于清洁和/或去角质皮肤的脱毛组合物，面部或护肤面膜组合物，以及具有有利性质的眼线。

88. 发明申请

WO2012147042A3 SOLID COSMETIC MAKEUP AND/OR CARE COMPOSITION 审中-公开
标题翻译：固体化妆品和/或护理组合物
公开(公告)号：WO2012147042A3
公开(公告)日：2012-12-27
申请号：PCT/IB2012052087
申请日：2012-04-26
申请人： OREAL , REMAUT GEOFFROY , RAVAUD MAGALI
发明人： REMAUT GEOFFROY , RAVAUD MAGALI
IPC分类号： A61K8/34 , A61K8/06 , A61K8/37 , A61K8/81 , A61Q9/00 , A61Q19/00
CPC分类号： A61K8/062 , A61K8/06 , A61K8/342 , A61K8/37 , A61K8/375 , A61K8/8147 , A61K2800/10 , A61Q1/02 , A61Q9/00 , A61Q17/04 , A61Q19/00 , A61Q19/005 , A61Q19/007 , A61Q19/08
摘要： The present invention relates to a cosmetic composition for making up and/or caring for keratin materials, in the form of an oil-in-water solid emulsion, comprising, in a physiologically acceptable medium: - from 4.0% to 8.0% by weight, relative to the total weight of the composition, of at least one fatty alcohol, - from 1.0% to 3.0% by weight, relative to the total weight of the composition, of at least one solid linear ester, - from 2.5% to 6.0% by weight, relative to the total weight of the composition, of at least one non-ethoxylated glyceryl stearate, and - from 0.25% to 0.50% by weight, relative to the total weight of the composition, of sodium polyacrylate.
摘要翻译：本发明涉及一种化妆品组合物，其用于以水包油型固体乳液的形式制备和/或照顾角蛋白材料，该组合物在生理学上可接受的介质中包含： - 4.0重量％〜8.0重量％相对于组合物的总重量，至少一种脂肪醇，相对于组合物的总重量为1.0重量％至3.0重量％的至少一种固体直链酯，为2.5至6.0重量％相对于组合物的总重量，至少一种非乙氧基化甘油硬脂酸酯，和相对于组合物总重量的0.25重量％至0.50重量％的聚丙烯酸钠。

89. 发明申请

WO2009077960A1 NOVEL COMPOUNDS USEFUL IN THERAPEUTIC AND COSMETIC METHODS 审中-公开
标题翻译：新的化合物在治疗和化妆方法中有用
公开(公告)号：WO2009077960A1
公开(公告)日：2009-06-25
申请号：PCT/IB2008/055272
申请日：2008-12-12
申请人： PHOTODERMA SA , GLANZMANN, Thomas , BARGE, Jérôme , WAGNIERES, Georges
发明人： GLANZMANN, Thomas , BARGE, Jérôme , WAGNIERES, Georges
IPC分类号： A61K8/37 , A61K8/44 , A61K8/49 , A61K8/60 , A61K8/63 , A61K8/67 , A61K31/221 , A61K31/222 , A61K31/223 , A61K8/35 , A61K8/41 , A61Q19/00
CPC分类号： A61K31/221 , A61K8/44 , A61K8/442 , A61K31/222 , A61K31/223 , A61K2800/81 , A61Q5/006 , A61Q9/00 , A61Q17/005 , A61Q19/008
摘要： The present invention relates to photosensitizer compounds for use in cosmetic and therapeutic applications of photodynamic therapy. The compounds of the present invention are designed for topical application and are characterized by a low permeability to the stratum corneum (the outer skin layer of an individual) and/or a low allergenic potential. Surprisingly, such compounds have beneficial properties in the treatment of certain diseases and lack the undesired damages to healthy skin entailed by prior art compounds. ALA(5-aminolevulinic acid) -esters of body- owned, natural compound such as aminoacids, steroids, carbohydrades, alcohols are preferred examples of photosensitizers of the present invention. The compounds of the present invention are used in the treatment of skin diseases such as psoriasis, sebaceous glands related conditions including acne, seborrhoic dermatitis, rosacea, skin cancer and precancer, as well as in cosmetic hair removal.
摘要翻译：本发明涉及用于光动力疗法的化妆品和治疗应用的光敏剂化合物。本发明的化合物被设计用于局部施用，其特征在于对角质层（个体的外皮层）的低渗透性和/或低变应原性。令人惊讶的是，这些化合物在某些疾病的治疗中具有有益的性质，并且对现有技术化合物所必需的健康皮肤缺乏不期望的损伤。氨基酸，类固醇，碳水化合物，醇类的人体所有的天然化合物的ALA（5-氨基乙酰丙酸）酯是本发明的光敏剂的优选实例。本发明的化合物用于治疗皮肤疾病如牛皮癣，皮脂腺相关病症，包括痤疮，脂溢性皮肤炎，酒渣鼻，皮肤癌和癌前病变，以及化妆品脱毛。

90. 发明申请

WO2008106966A1 A METHOD FOR NON-THERAPEUTIC OR THERAPEUTIC PHOTODYNAMIC SKIN TREATMENT 审中-公开
标题翻译：一种非治疗性或治疗性光敏性皮肤治疗方法
公开(公告)号：WO2008106966A1
公开(公告)日：2008-09-12
申请号：PCT/DK2007/050029
申请日：2007-03-06
申请人： CHRISTIANSEN, Kåre , BJERRING, Peter , VAN DER BEEK, Klaas
发明人： CHRISTIANSEN, Kåre , BJERRING, Peter , VAN DER BEEK, Klaas
IPC分类号： A61K41/00 , A61P17/00 , A61P17/10 , A61K31/195 , A61K8/44 , A61Q19/08 , A61Q9/00
CPC分类号： A61K8/44 , A61K41/0057 , A61K41/0061 , A61K41/0066 , A61K2800/81 , A61Q9/00 , A61Q19/08
摘要： In a method for non-therapeutic or therapeutic photodynamic treatment of a skin target area, a photosensitizer fluid incorporating a photosensitizing agent or a precursor for a photosensitizing agent is delivered to the target area, the photosensitizing agent having at least one absorption wavelength in a wavelength range higher than 400 nm. The target area is then exposed to light energy in a range of wavelengths comprising at least one absorption wavelength of the photosensitizing agent, the light energy being supplied to the target area in the form of at least one light pulse producing in the target area an accumulated energy density sufficient for photodynamic activation of the photosensitizing agent. The photosensitizing agent or precursor is incorporated in the photosensitizer fluid with a concentration in the range from 0.1 to 2.0 % preferably from 05 to 1.0 %, and the photosensitizer fluid is delivered to the target area in the form of a number of repeated spray doses during an overall delivery time ranging from 0.25 to 8 hours. The method can be applied to cosmetic treatments for skin rejuvenation, reduction of wrinkles, treatment of telangiectasia or removal of hair as wells a medical treatment of dermatologic diseases such as acne vulgaris, acne scars, rosacea, psorieasis, actinic keratoses, basal cell carcinoma, Bowen's disease or eczema.
摘要翻译：在用于非治疗或治疗光动力治疗皮肤靶区的方法中，将含有光敏剂或光敏剂的前体的光敏剂流体输送到目标区域，所述光敏剂具有至少一种波长的吸收波长范围高于400 nm。然后将目标区域暴露于包括光敏剂的至少一个吸收波长的波长范围内的光能，光能以在目标区域中产生的至少一个光脉冲的形式被提供给目标区域，累积能量密度足以使光敏剂的光动力激活。将光敏剂或前体掺入光敏剂流体中，浓度范围为0.1至2.0％，优选为05至1.0％，并且将光敏剂流体以多次重复喷雾剂量的形式递送至目标区域整体交货时间为0.25至8小时。该方法可应用于皮肤复原，减少皱纹，治疗毛细血管扩张或去除毛发的美容治疗，例如寻常痤疮，痤疮疤痕，红斑痤疮，银屑病，光化性角化病，基底细胞癌等皮肤科疾病的治疗，鲍文氏病或湿疹。

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